(Q38036102)

27 August 2017

Pre-rheumatoid arthritis: predisposition and transition to clinical synovitis (English)

1 reference

27 August 2017

1 reference

William P Arend

1

1 reference

27 August 2017

Gary S Firestein

series ordinal

2

1 reference

27 August 2017

language of work or name

English

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publication date

21 August 2012

1 reference

Nature Reviews Rheumatology

27 August 2017

1 reference

27 August 2017

8

1 reference

27 August 2017

10

1 reference

27 August 2017

573-586

1 reference

https://scigraph.springernature.com/pub.10.1038/nrrheum.2012.134

27 August 2017

0 references

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Immunity to citrullinated proteins in rheumatoid arthritis

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Preclinical rheumatoid arthritis: identification, evaluation, and future directions for investigation

21 January 2018

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Recent advances in the genetics of rheumatoid arthritis

21 January 2018

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Learning about the natural history of rheumatoid arthritis development through prospective study of subjects at high risk of rheumatoid arthritis-related autoimmunity

21 January 2018

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Characterizing the quantitative genetic contribution to rheumatoid arthritis using data from twins

21 January 2018

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Quantitative heritability of anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis.

21 January 2018

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Association of the B-cell alloantigen DRw4 with rheumatoid arthritis

21 January 2018

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Protection against anti-citrullinated protein antibody-positive rheumatoid arthritis is predominantly associated with HLA-DRB1*1301: a meta-analysis of HLA-DRB1 associations with anti-citrullinated protein antibody-positive and anti-citrullinated pr

21 January 2018

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The shared epitope hypothesis. An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis

21 January 2018

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Refining the complex rheumatoid arthritis phenotype based on specificity of the HLA-DRB1 shared epitope for antibodies to citrullinated proteins

21 January 2018

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Cutting edge: the conversion of arginine to citrulline allows for a high-affinity peptide interaction with the rheumatoid arthritis-associated HLA-DRB1*0401 MHC class II molecule

21 January 2018

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Immune dysregulation by the rheumatoid arthritis shared epitope

21 January 2018

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Hologram and 3D-quantitative structure toxicity relationship studies of azo dyes

21 January 2018

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Different patterns of associations with anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis in the extended major histocompatibility complex region

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Genetic association of the major histocompatibility complex with rheumatoid arthritis implicates two non-DRB1 loci

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Cumulative association of 22 genetic variants with seropositive rheumatoid arthritis risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Unraveling the functional implications of GWAS: how T cell protein tyrosine phosphatase drives autoimmune disease.

21 January 2018

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Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant

21 January 2018

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T cell protein tyrosine phosphatase attenuates T cell signaling to maintain tolerance in mice

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Association of HLA-DR3 with anti-cyclic citrullinated peptide antibody-negative rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Association of a haplotype in the promoter region of the interferon regulatory factor 5 gene with rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Primer: epigenetics of autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

DNA methylation and human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Modification of nuclear PML protein by SUMO-1 regulates Fas-induced apoptosis in rheumatoid arthritis synovial fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Epigenetic mechanisms in mammals

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Epigenetics in rheumatoid arthritis.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Inflammatory memories: is epigenetics the missing link to persistent stromal cell activation in rheumatoid arthritis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Invasive fibroblast-like synoviocytes in rheumatoid arthritis. Passive responders or transformed aggressors?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Expression and function of histone deacetylases in rheumatoid arthritis synovial fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Animal models to study environmental epigenetics

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Altered expression of microRNA-203 in rheumatoid arthritis synovial fibroblasts and its role in fibroblast activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Altered expression of MicroRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

What do microRNAs mean for rheumatoid arthritis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Roles for microRNAs in conferring robustness to biological processes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

MicroRNAs in stress signaling and human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Interactions between commensal intestinal bacteria and the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

The gut microbiota shapes intestinal immune responses during health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Influence of microbial environment on autoimmunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Normal intestinal microbiota in the aetiopathogenesis of rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Development of chronic inflammatory arthropathy resembling rheumatoid arthritis in interleukin 1 receptor antagonist-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Gut-residing segmented filamentous bacteria drive autoimmune arthritis via T helper 17 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Predicting a human gut microbiota's response to diet in gnotobiotic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Incomplete recovery and individualized responses of the human distal gut microbiota to repeated antibiotic perturbation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Toll-like receptors in rheumatic diseases: are we paying a high price for our defense against bugs?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Toll-like receptors in systemic autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Intrinsic danger: activation of Toll-like receptors in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Interleukin 1 receptor dependence of serum transferred arthritis can be circumvented by toll-like receptor 4 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Peptidylarginine deiminase 2, 3 and 4 have distinct specificities against cellular substrates: novel insights into autoantigen selection in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Association of autoimmunity to peptidyl arginine deiminase type 4 with genotype and disease severity in rheumatoid arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Autoimmunity to peptidyl arginine deiminase type 4 precedes clinical onset of rheumatoid arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Coordination of PAD4 and HDAC2 in the regulation of p53-target gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Smoking, citrullination and genetic variability in the immunopathogenesis of rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Periodontitis in systemic rheumatic diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

The association between rheumatoid arthritis and periodontal disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Periodontitis in RA-the citrullinated enolase connection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Peptidylarginine deiminase from Porphyromonas gingivalis citrullinates human fibrinogen and α-enolase: implications for autoimmunity in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Quantification of the influence of cigarette smoking on rheumatoid arthritis: results from a population based case-control study, using incident cases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Cigarette smoking increases the risk of rheumatoid arthritis. Results from a nationwide study of disease-discordant twins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

A gene-environment interaction between smoking and shared epitope genes in HLA-DR provides a high risk of seropositive rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Smoking is a risk factor for anti-CCP antibodies only in rheumatoid arthritis patients who carry HLA-DRB1 shared epitope alleles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

A new model for an etiology of rheumatoid arthritis: smoking may trigger HLA-DR (shared epitope)-restricted immune reactions to autoantigens modified by citrullination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Smoking increases peptidylarginine deiminase 2 enzyme expression in human lungs and increases citrullination in BAL cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Smoking as a trigger for inflammatory rheumatic diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Association of smoking with the constitution of the anti-cyclic citrullinated peptide response in the absence of HLA-DRB1 shared epitope alleles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Genetic polymorphisms in PTPN22, PADI-4, and CTLA-4 and risk for rheumatoid arthritis in two longitudinal cohort studies: evidence of gene-environment interactions with heavy cigarette smoking

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Gene-gene and gene-environment interactions involving HLA-DRB1, PTPN22, and smoking in two subsets of rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Reevaluation of the interaction between HLA-DRB1 shared epitope alleles, PTPN22, and smoking in determining susceptibility to autoantibody-positive and autoantibody-negative rheumatoid arthritis in a large UK Caucasian population

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Smoking is a major preventable risk factor for rheumatoid arthritis: estimations of risks after various exposures to cigarette smoke

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

The interaction between HLA shared epitope alleles and smoking and its contribution to autoimmunity against several citrullinated antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Effect of interactions of glutathione S-transferase T1, M1, and P1 and HMOX1 gene promoter polymorphisms with heavy smoking on the risk of rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Associations of cigarette smoking with rheumatoid arthritis in African Americans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Impact of interactions of cigarette smoking with NAT2 polymorphisms on rheumatoid arthritis risk in African Americans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Silica exposure among male current smokers is associated with a high risk of developing ACPA-positive rheumatoid arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

The influence of early life factors on the risk of developing rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Is birthweight associated with risk of rheumatoid arthritis? Data from a large cohort study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Do breast-feeding and other reproductive factors influence future risk of rheumatoid arthritis? Results from the Nurses' Health Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Exposure to traffic pollution and increased risk of rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

The preclinical stages of RA: lessons from human studies and animal models

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Autoimmunity to specific citrullinated proteins gives the first clues to the etiology of rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

The influence of ACPA status and characteristics on the course of RA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

The presence of citrullinated proteins is not specific for rheumatoid synovial tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Citrullination is an inflammation-dependent process

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Antibodies to several citrullinated antigens are enriched in the joints of rheumatoid arthritis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Brief report: airways abnormalities and rheumatoid arthritis-related autoantibodies in subjects without arthritis: early injury or initiating site of autoimmunity?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

21 January 2018

Rheumatoid lung disease

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Autoantibodies recognizing carbamylated proteins are present in sera of patients with rheumatoid arthritis and predict joint damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Carbamylation-dependent activation of T cells: a novel mechanism in the pathogenesis of autoimmune arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Specific autoantibodies precede the symptoms of rheumatoid arthritis: a study of serial measurements in blood donors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Antibodies against cyclic citrullinated peptide and IgA rheumatoid factor predict the development of rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

The likelihood of persistent arthritis increases with the level of anti-citrullinated peptide antibody and immunoglobulin M rheumatoid factor: a longitudinal study of 376 patients with very early undifferentiated arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Prediction models for rheumatoid arthritis during diagnostic investigation: evaluation of combinations of rheumatoid factor, anti-citrullinated protein/peptide antibodies and the human leucocyte antigen-shared epitope

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Proteomic analysis of secreted proteins in early rheumatoid arthritis: anti-citrulline autoreactivity is associated with up regulation of proinflammatory cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Up regulation of monocyte chemoattractant protein-1 expression in anti-citrulline antibody and immunoglobulin M rheumatoid factor positive subjects precedes onset of inflammatory response and development of overt rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Cytokines, autoantibodies and viral antibodies in premorbid and postdiagnostic sera from patients with rheumatoid arthritis: case-control study nested in a cohort of Norwegian blood donors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Familial clustering of the serum cytokine profile in the relatives of rheumatoid arthritis patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

The number of elevated cytokines and chemokines in preclinical seropositive rheumatoid arthritis predicts time to diagnosis in an age-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Evaluation of therapeutic targets in animal models of arthritis: how does it relate to rheumatoid arthritis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

How antibodies to a ubiquitous cytoplasmic enzyme may provoke joint-specific autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Staging the initiation of autoantibody-induced arthritis: a critical role for immune complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Particularities of the vasculature can promote the organ specificity of autoimmune attack.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Structure and pathogenicity of antibodies specific for citrullinated collagen type II in experimental arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Antibodies to citrullinated proteins: molecular interactions and arthritogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Early structural changes in cartilage and bone are required for the attachment and invasion of inflamed synovial tissue during destructive inflammatory arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

The development of clinical signs of rheumatoid synovial inflammation is associated with increased synthesis of the chemokine CXCL8 (interleukin-8)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Asymptomatic synovitis precedes clinically manifest arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Kinetic analysis of synovial signalling and gene expression in animal models of arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Circulating immune complexes contain citrullinated fibrinogen in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

High anti-collagen type-II antibody levels and induction of proinflammatory cytokines by anti-collagen antibody-containing immune complexes in vitro characterise a distinct rheumatoid arthritis phenotype associated with acute inflammation at the tim

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Anti-type II collagen antibodies are associated with early radiographic destruction in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Arthritogenic antibodies specific for a major type II collagen triple-helical epitope bind and destabilize cartilage independent of inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Multifunctional T cell reactivity with native and glycosylated type II collagen in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Expression of FcgammaRIII is required for development of collagen-induced arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Arthritis critically dependent on innate immune system players

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Dissection of the FCGR3A association with RA: increased association in men and with autoantibody positive disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Rheumatoid arthritis and the complement system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Increased frequency of complement C4B deficiency in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Cytokines in the pathogenesis of rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Synovial interleukin-1 receptor antagonist and interleukin-1 balance in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

The balance between IL-1 and IL-1Ra in disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Rheumatoid arthritis synovium contains two subsets of CD83-DC-LAMP- dendritic cells with distinct cytokine profiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

A candidate gene approach identifies the TRAF1/C5 region as a risk factor for rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Two independent alleles at 6q23 associated with risk of rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Association of single-nucleotide polymorphisms in CCR6, TAGAP, and TNFAIP3 with rheumatoid arthritis in African Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

NLRP1 gene polymorphism influences gene transcription and is a risk factor for rheumatoid arthritis in han chinese.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Common variants at CD40 and other loci confer risk of rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

A therapeutic strategy uses histone deacetylase inhibitors to modulate the expression of genes involved in the pathogenesis of rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Histone deacetylase inhibitor suppression of autoantibody-mediated arthritis in mice via regulation of p16INK4a and p21(WAF1/Cip1) expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Histone deacetylase inhibitors suppress rheumatoid arthritis fibroblast-like synoviocyte and macrophage IL-6 production by accelerating mRNA decay

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Retrotransposable L1 elements expressed in rheumatoid arthritis synovial tissue: association with genomic DNA hypomethylation and influence on gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Overexpression of transcripts containing LINE-1 in the synovia of patients with rheumatoid arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

DNA hypomethylation in rheumatoid arthritis synovial fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

DNA methylation regulates the expression of CXCL12 in rheumatoid arthritis synovial fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Expression of microRNA-146 in rheumatoid arthritis synovial tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

MicroRNA-124a is a key regulator of proliferation and monocyte chemoattractant protein 1 secretion in fibroblast-like synoviocytes from patients with rheumatoid arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Down-regulation of microRNA-34a* in rheumatoid arthritis synovial fibroblasts promotes apoptosis resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

The HLA–DRB1 shared epitope alleles are primarily a risk factor for anti–cyclic citrullinated peptide antibodies and are not an independent risk factor for development of rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

PADI4 polymorphism predisposes male smokers to rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Anti-cyclic citrullinated peptide antibodies from rheumatoid arthritis patients activate complement via both the classical and alternative pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Avidity maturation of anti-citrullinated protein antibodies in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

The contribution of HLA to rheumatoid arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Several regions in the major histocompatibility complex confer risk for anti-CCP-antibody positive rheumatoid arthritis, independent of the DRB1 locus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

The impact of perinatal immune development on mucosal homeostasis and chronic inflammation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

The microbiome and rheumatoid arthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Diet and intestinal immunity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

TLR-dependent T cell activation in autoimmunity.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Expression of Toll-like receptors and their signaling pathways in rheumatoid synovitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Frequency of infections among rheumatoid arthritis patients, before and after disease onset

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Periodontal disease and the oral microbiota in new-onset rheumatoid arthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Oral contraceptives, cigarette smoking and other factors in relation to arthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

α-Enolase expressed on the surfaces of monocytes and macrophages induces robust synovial inflammation in rheumatoid arthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Different stages of rheumatoid arthritis: features of the synovium in the preclinical phase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

AP-1 and NF-kappaB regulation in rheumatoid arthritis and murine collagen-induced arthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Anti-citrullinated protein antibody response associated with synovial immune deposits in a patient with suspected early rheumatoid arthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Surface-bound anti-type II collagen-containing immune complexes induce production of tumor necrosis factor alpha, interleukin-1beta, and interleukin-8 from peripheral blood monocytes via Fc gamma receptor IIA: a potential pathophysiologic mechanism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Pathogenic complement activation in collagen antibody-induced arthritis in mice requires amplification by the alternative pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

A regulatory variant in CCR6 is associated with rheumatoid arthritis susceptibility

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Inhibition of HDAC activity by ITF2357 ameliorates joint inflammation and prevents cartilage and bone destruction in experimental arthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Evidence for impaired T cell DNA methylation in systemic lupus erythematosus and rheumatoid arthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Global DNA methylation, DNMT1, and MBD2 in patients with rheumatoid arthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

DNA methylome signature in rheumatoid arthritis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

Increased recycling of polyamines is associated with global DNA hypomethylation in rheumatoid arthritis synovial fibroblasts

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2012.134

FcγRIIIa expression on monocytes in rheumatoid arthritis: role in immune-complex stimulated TNF production and non-response to methotrexate therapy

31 March 2020

1 reference

12 December 2020

Should infection still be considered as the most likely triggering factor for rheumatoid arthritis?

1 reference

12 December 2020

Up-regulation of cytokines and chemokines predates the onset of rheumatoid arthritis

1 reference

12 December 2020

In utero supplementation with methyl donors enhances allergic airway disease in mice

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRRHEUM.2012.134

1 reference

Dimensions Publication ID

27 August 2017

0 references

1 reference