(Q38044441)

27 August 2017

title

LRRK2 and vesicle trafficking (English)

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27 August 2017

Giovanna Sanna

1

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27 August 2017

Maria Grazia Del Giudice

series ordinal

2

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27 August 2017

Claudia Crosio

series ordinal

3

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27 August 2017

Ciro Iaccarino

series ordinal

4

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27 August 2017

publication date

1 October 2012

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Biochemical Society Transactions

27 August 2017

published in

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27 August 2017

volume

40

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27 August 2017

issue

5

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27 August 2017

page(s)

1117-1122

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Parkinson's disease: mechanisms and models

27 August 2017

cites work

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Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity

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Kinase activity of mutant LRRK2 mediates neuronal toxicity

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Pathogenic LRRK2 negatively regulates microRNA-mediated translational repression

21 January 2018

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Phosphorylation of 4E-BP by LRRK2 affects the maintenance of dopaminergic neurons in Drosophila

21 January 2018

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Phosphorylation of ezrin/radixin/moesin proteins by LRRK2 promotes the rearrangement of actin cytoskeleton in neuronal morphogenesis

21 January 2018

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Leucine-rich repeat kinase 2 phosphorylates brain tubulin-beta isoforms and modulates microtubule stability--a point of convergence in parkinsonian neurodegeneration?

21 January 2018

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Impaired dopaminergic neurotransmission and microtubule-associated protein tau alterations in human LRRK2 transgenic mice

21 January 2018

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Dopaminergic neuronal loss, reduced neurite complexity and autophagic abnormalities in transgenic mice expressing G2019S mutant LRRK2.

21 January 2018

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Loss of leucine-rich repeat kinase 2 causes impairment of protein degradation pathways, accumulation of alpha-synuclein, and apoptotic cell death in aged mice

21 January 2018

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The kinase LRRK2 is a regulator of the transcription factor NFAT that modulates the severity of inflammatory bowel disease

21 January 2018

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Localization of Parkinson's disease-associated LRRK2 in normal and pathological human brain

21 January 2018

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LRRK2 is expressed in areas affected by Parkinson's disease in the adult mouse brain.

21 January 2018

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Distribution of PINK1 and LRRK2 in rat and mouse brain

21 January 2018

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LRRK2 expression linked to dopamine-innervated areas

21 January 2018

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Anatomical localization of leucine-rich repeat kinase 2 in mouse brain

21 January 2018

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Lrrk2 localization in the primate basal ganglia and thalamus: a light and electron microscopic analysis in monkeys

21 January 2018

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A comparative analysis of leucine-rich repeat kinase 2 (Lrrk2) expression in mouse brain and Lewy body disease

21 January 2018

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Localization of LRRK2 to membranous and vesicular structures in mammalian brain

21 January 2018

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Parkinson's disease-linked leucine-rich repeat kinase 2(R1441G) mutation increases proinflammatory cytokine release from activated primary microglial cells and resultant neurotoxicity.

21 January 2018

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Apoptotic mechanisms in mutant LRRK2-mediated cell death

21 January 2018

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Non-cell autonomous toxicity in neurodegenerative disorders: ALS and beyond

21 January 2018

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Leucine-rich repeat kinase 2 associates with lipid rafts

21 January 2018

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Functions of lipid rafts in biological membranes

21 January 2018

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Cholesterol binds to synaptophysin and is required for biogenesis of synaptic vesicles

21 January 2018

1 reference

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Synaptic proteins and SNARE complexes are localized in lipid rafts from rat brain synaptosomes

21 January 2018

1 reference

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Membrane localization of LRRK2 is associated with increased formation of the highly active LRRK2 dimer and changes in its phosphorylation

21 January 2018

1 reference

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Dependence of leucine-rich repeat kinase 2 (LRRK2) kinase activity on dimerization

21 January 2018

1 reference

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Re-examination of the dimerization state of leucine-rich repeat kinase 2: predominance of the monomeric form

21 January 2018

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Mitochondrial dysfunction in genetic animal models of Parkinson's disease

21 January 2018

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Mitochondrial impairment in patients with Parkinson disease with the G2019S mutation in LRRK2.

21 January 2018

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LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool

21 January 2018

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LRK-1, a C. elegans PARK8-related kinase, regulates axonal-dendritic polarity of SV proteins

21 January 2018

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LRRK2-mediated neurodegeneration and dysfunction of dopaminergic neurons in a Caenorhabditis elegans model of Parkinson's disease

21 January 2018

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Mutant LRRK2(R1441G) BAC transgenic mice recapitulate cardinal features of Parkinson's disease

21 January 2018

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Enhanced striatal dopamine transmission and motor performance with LRRK2 overexpression in mice is eliminated by familial Parkinson's disease mutation G2019S

21 January 2018

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Temporal expression of mutant LRRK2 in adult rats impairs dopamine reuptake

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120117

LRRK2 regulates synaptic vesicle endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120117

GTPase activity and neuronal toxicity of Parkinson's disease-associated LRRK2 is regulated by ArfGAP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120117

ArfGAP1 is a GTPase activating protein for LRRK2: reciprocal regulation of ArfGAP1 by LRRK2

21 January 2018

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ARF family G proteins and their regulators: roles in membrane transport, development and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120117

Regulating cytoskeleton-based vesicle motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120117

Mobility and cycling of synaptic protein–containing vesicles in axonal growth cone filopodia

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120117

The Roc domain of leucine-rich repeat kinase 2 is sufficient for interaction with microtubules

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120117

LRRK2 phosphorylates tubulin-associated tau but not the free molecule: LRRK2-mediated regulation of the tau-tubulin association and neurite outgrowth

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBST20120117

21 January 2018

Identifiers

DOI

10.1042/BST20120117

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27 August 2017

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