(Q38044988)

27 August 2017

title

New insights into the control of neurotrophic growth factor receptor signaling: implications for nervous system development and repair (English)

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27 August 2017

Fernando C Alsina

1

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27 August 2017

Fernanda Ledda

series ordinal

2

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27 August 2017

Gustavo Paratcha

series ordinal

3

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27 August 2017

language of work or name

English

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publication date

10 October 2012

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Journal of Neurochemistry

27 August 2017

published in

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27 August 2017

volume

123

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27 August 2017

issue

5

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27 August 2017

page(s)

652-661

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Changes in Sef levels influence auditory brainstem development and function.

27 August 2017

cites work

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The GDNF family: signalling, biological functions and therapeutic value

21 January 2018

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Sprouty4 is an endogenous negative modulator of TrkA signaling and neuronal differentiation induced by NGF

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Identification and characterization of Slitrk, a novel neuronal transmembrane protein family controlling neurite outgrowth

21 January 2018

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Endocytic trafficking of neurotrophins in neural development

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Early striatal dendrite deficits followed by neuron loss with advanced age in the absence of anterograde cortical brain-derived neurotrophic factor.

21 January 2018

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Sprouty proteins, masterminds of receptor tyrosine kinase signaling

21 January 2018

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AMIGO and friends: an emerging family of brain-enriched, neuronal growth modulating, type I transmembrane proteins with leucine-rich repeats (LRR) and cell adhesion molecule motifs

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Neurotrophins and neurodegeneration.

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Spred1 is required for synaptic plasticity and hippocampus-dependent learning

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Negative receptor signalling

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The bimodal regulation of epidermal growth factor signaling by human Sprouty proteins

21 January 2018

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Proneurotrophins, seizures, and neuronal apoptosis

21 January 2018

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Sef is a feedback-induced antagonist of Ras/MAPK-mediated FGF signalling.

21 January 2018

1 reference

Negative regulation of HER2 signaling by the PEST-type protein-tyrosine phosphatase BDP1.

21 January 2018

1 reference

The transmembrane molecule kekkon 1 acts in a feedback loop to negatively regulate the activity of the Drosophila EGF receptor during oogenesis.

21 January 2018

1 reference

Mechanism of inhibition of the Drosophila and mammalian EGF receptors by the transmembrane protein Kekkon 1.

21 January 2018

1 reference

Retrograde neurotrophin signaling: Trk-ing along the axon

21 January 2018

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The role of neurotrophic factors in nerve regeneration

21 January 2018

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Sprouty2 inhibits BDNF-induced signaling and modulates neuronal differentiation and survival.

21 January 2018

1 reference

LRIG1 restricts growth factor signaling by enhancing receptor ubiquitylation and degradation

21 January 2018

1 reference

Mig-6 is a negative regulator of the epidermal growth factor receptor signal

21 January 2018

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sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways

21 January 2018

1 reference

Sprouty2 acts at the Cbl/CIN85 interface to inhibit epidermal growth factor receptor downregulation

21 January 2018

1 reference

Is LRIG1 a tumour suppressor gene at chromosome 3p14.3?

21 January 2018

1 reference

Induction of corticospinal regeneration by lentiviral trkB-induced Erk activation

21 January 2018

1 reference

Cytoplasmic LRIG2 expression is associated with poor oligodendroglioma patient survival

21 January 2018

1 reference

Mammalian sprouty-1 and -2 are membrane-anchored phosphoprotein inhibitors of growth factor signaling in endothelial cells

21 January 2018

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Inhibition of the leucine-rich repeat protein LINGO-1 enhances survival, structure, and function of dopaminergic neurons in Parkinson's disease models

21 January 2018

1 reference

Sprouty2 regulates growth and differentiation of human neuroblastoma cells through RET tyrosine kinase

21 January 2018

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Disorganized innervation and neuronal loss in the inner ear of Slitrk6-deficient mice

21 January 2018

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PTEN modulates GDNF/RET mediated chemotaxis and branching morphogenesis in the developing kidney

21 January 2018

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Sef inhibits fibroblast growth factor signaling by inhibiting FGFR1 tyrosine phosphorylation and subsequent ERK activation

21 January 2018

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Cooperation between GDNF/Ret and ephrinA/EphA4 signals for motor-axon pathway selection in the limb

21 January 2018

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Absence of Ret signaling in mice causes progressive and late degeneration of the nigrostriatal system

21 January 2018

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Lrig1 is an estrogen-regulated growth suppressor and correlates with longer relapse-free survival in ERα-positive breast cancer

21 January 2018

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The leucine-rich repeat protein LRIG1 is a negative regulator of ErbB family receptor tyrosine kinases

21 January 2018

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Lrig1 is an endogenous inhibitor of Ret receptor tyrosine kinase activation, downstream signaling, and biological responses to GDNF.

21 January 2018

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Synergistic activity of Sef and Sprouty proteins in regulating the expression of Gbx2 in the mid-hindbrain region.

21 January 2018

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Encapsulated cell biodelivery of GDNF: a novel clinical strategy for neuroprotection and neuroregeneration in Parkinson's disease?

21 January 2018

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PTEN deletion enhances the regenerative ability of adult corticospinal neurons

21 January 2018

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SLAM-associated protein as a potential negative regulator in Trk signaling

21 January 2018

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The PTEN/MMAC1/TEP tumor suppressor gene decreases cell growth and induces apoptosis and anoikis in breast cancer cells

21 January 2018

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LIG family receptor tyrosine kinase-associated proteins modulate growth factor signals during neural development

21 January 2018

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Sprouty proteins: multifaceted negative-feedback regulators of receptor tyrosine kinase signaling.

21 January 2018

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Neurotrophic factors in combinatorial approaches for spinal cord regeneration

21 January 2018

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LINGO-1 negatively regulates myelination by oligodendrocytes

21 January 2018

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Promotion of central nervous system remyelination by induced differentiation of oligodendrocyte precursor cells

21 January 2018

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Cloning, characterization, and expression of human LIG1.

21 January 2018

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Characterisation of a new regulator of BDNF signalling, Sprouty3, involved in axonal morphogenesis in vivo

21 January 2018

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Mitogen-inducible gene 6 is an endogenous inhibitor of HGF/Met-induced cell migration and neurite growth

21 January 2018

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GDNF and GFRalpha: a versatile molecular complex for developing neurons

21 January 2018

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Peripheral NT3 signaling is required for ETS protein expression and central patterning of proprioceptive sensory afferents

21 January 2018

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Spred1, a negative regulator of Ras-MAPK-ERK, is enriched in CNS germinal zones, dampens NSC proliferation, and maintains ventricular zone structure

21 January 2018

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The pan-ErbB negative regulator Lrig1 is an intestinal stem cell marker that functions as a tumor suppressor

21 January 2018

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Alternative splicing generates an isoform of the human Sef gene with altered subcellular localization and specificity

21 January 2018

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Slitrks as emerging candidate genes involved in neuropsychiatric disorders

21 January 2018

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Neurotrophin-regulated signalling pathways

21 January 2018

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Sprouty fine-tunes EGF signaling through interlinked positive and negative feedback loops

21 January 2018

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Identification of a dominant negative mutant of Sprouty that potentiates fibroblast growth factor- but not epidermal growth factor-induced ERK activation

21 January 2018

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LRIG1 is a novel negative regulator of the Met receptor and opposes Met and Her2 synergy

21 January 2018

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Expression of neurotrophin mRNAs in the dorsal root ganglion after spinal nerve injury

21 January 2018

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ProNGF induces PTEN via p75NTR to suppress Trk-mediated survival signaling in brain neurons

21 January 2018

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Neuronal intrinsic barriers for axon regeneration in the adult CNS.

21 January 2018

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c-Cbl and Cbl-b ubiquitin ligases: substrate diversity and the negative regulation of signalling responses

21 January 2018

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Sef is a spatial regulator for Ras/MAP kinase signaling

21 January 2018

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Promotion and attenuation of FGF signaling through the Ras-MAPK pathway

21 January 2018

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Spred is a Sprouty-related suppressor of Ras signalling

21 January 2018

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Downregulation of LRIG2 expression by RNA interference inhibits glioblastoma cell (GL15) growth, causes cell cycle redistribution, increases cell apoptosis and enhances cell adhesion and invasion in vitro

21 January 2018

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Functional SLITRK1 var321, varCDfs and SLC6A4 G56A variants and susceptibility to obsessive-compulsive disorder.

21 January 2018

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Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neurons

21 January 2018

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Evidence for direct interaction between Sprouty and Cbl

21 January 2018

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Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling

21 January 2018

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Upregulation of LRIG1 suppresses malignant glioma cell growth by attenuating EGFR activity

21 January 2018

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Paracrine regulation of growth factor signaling by shed leucine-rich repeats and immunoglobulin-like domains 1

21 January 2018

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Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface

21 January 2018

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LINGO-1 antagonist promotes spinal cord remyelination and axonal integrity in MOG-induced experimental autoimmune encephalomyelitis

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/JNC.12021

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27 August 2017

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