(Q34374013)

1 August 2017

title

ProNGF induces PTEN via p75NTR to suppress Trk-mediated survival signaling in brain neurons (English)

1 reference

1 August 2017

Wenyu Song

1

1 reference

1 August 2017

Marta Volosin

2

1 reference

1 August 2017

Andrea B Cragnolini

3

1 reference

1 August 2017

Barbara L Hempstead

4

1 reference

1 August 2017

Wilma J Friedman

5

1 reference

1 August 2017

language of work or name

English

0 references

publication date

1 November 2010

1 reference

1 August 2017

published in

Journal of Neuroscience

1 reference

1 August 2017

volume

30

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1 August 2017

issue

46

1 reference

1 August 2017

page(s)

15608-15615

1 reference

EGF-induced ERK activation promotes CK2-mediated disassociation of alpha-Catenin from beta-Catenin and transactivation of beta-Catenin.

1 August 2017

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The Parkinson disease protein leucine-rich repeat kinase 2 transduces death signals via Fas-associated protein with death domain and caspase-8 in a cellular model of neurodegeneration

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Induction of proneurotrophins and activation of p75NTR-mediated apoptosis via neurotrophin receptor-interacting factor in hippocampal neurons after seizures

6 July 2018

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The roles of PTEN in development, physiology and tumorigenesis in mouse models: a tissue-by-tissue survey

6 July 2018

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The p75 neurotrophin receptor is a central regulator of glioma invasion

6 July 2018

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6 July 2018

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PTEN is destabilized by phosphorylation on Thr366.

6 July 2018

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Pro-NGF secreted by astrocytes promotes motor neuron cell death

6 July 2018

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Neurotrophin-regulated signalling pathways

6 July 2018

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Interaction of survival and death signaling in basal forebrain neurons: roles of neurotrophins and proneurotrophins.

6 July 2018

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PCAF modulates PTEN activity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996105

Pro-NGF from Alzheimer's disease and normal human brain displays distinctive abilities to induce processing and nuclear translocation of intracellular domain of p75NTR and apoptosis

6 July 2018

1 reference

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Neurotrophin signaling: many exciting surprises!

6 July 2018

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Pten regulates neuronal arborization and social interaction in mice

6 July 2018

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ProBDNF induces neuronal apoptosis via activation of a receptor complex of p75NTR and sortilin.

6 July 2018

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Subset of individuals with autism spectrum disorders and extreme macrocephaly associated with germline PTEN tumour suppressor gene mutations

6 July 2018

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Pro-NGF isolated from the human brain affected by Alzheimer's disease induces neuronal apoptosis mediated by p75NTR.

6 July 2018

1 reference

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Bisperoxovanadium compounds are potent PTEN inhibitors.

6 July 2018

1 reference

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Secreted proNGF is a pathophysiological death-inducing ligand after adult CNS injury

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996105

Sortilin is essential for proNGF-induced neuronal cell death

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996105

Lesions of the Basal forebrain cholinergic system impair task acquisition and abolish cortical plasticity associated with motor skill learning

6 July 2018

1 reference

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Ethanol impairs insulin-stimulated neuronal survival in the developing brain: role of PTEN phosphatase

6 July 2018

1 reference

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ProNGF induces p75-mediated death of oligodendrocytes following spinal cord injury

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996105

Neurotrophin signaling through the p75 neurotrophin receptor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996105

Mechanisms of p75-mediated death of hippocampal neurons. Role of caspases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996105

Negative feedback regulation of the tumor suppressor PTEN by phosphoinositide-induced serine phosphorylation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996105

Reversible inactivation of the tumor suppressor PTEN by H2O2

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996105

Regulation of cell survival by secreted proneurotrophins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996105

Phosphorylation of the PTEN tail acts as an inhibitory switch by preventing its recruitment into a protein complex

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996105

Neurotrophins: roles in neuronal development and function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996105

The precursor pro-nerve growth factor is the predominant form of nerve growth factor in brain and is increased in Alzheimer's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996105

Characterization of a p75(NTR) apoptotic signaling pathway using a novel cellular model

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996105

Trk receptors: mediators of neurotrophin action

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996105

Neurotrophins: key regulators of cell fate and cell shape in the vertebrate nervous system

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996105

Phosphorylation of the PTEN tail regulates protein stability and function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996105

A role for nuclear PTEN in neuronal differentiation.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996105

Neurotrophin signaling via Trks and p75.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996105

Neuroprotective actions of dipyridamole on cultured CNS neurons.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996105

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996105

Physiology of the neurotrophins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996105

Differential actions of neurotrophins in the locus coeruleus and basal forebrain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996105

Activation of a tumor-associated protein kinase (p40TAK) and casein kinase 2 in human squamous cell carcinomas and adenocarcinomas of the lung

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996105

Alzheimer's disease and senile dementia: loss of neurons in the basal forebrain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996105

Specific retrograde transport of nerve growth factor (NGF) from neocortex to nucleus basalis in the rat.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996105

Brain-derived neurotrophic factor increases survival and differentiated functions of rat septal cholinergic neurons in culture

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996105

Highly efficient small interfering RNA delivery to primary mammalian neurons induces MicroRNA-like effects before mRNA degradation.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996105

Correlation between synaptogenesis and the PTEN phosphatase expression in dendrites during postnatal brain development

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996105

Increased proNGF levels in subjects with mild cognitive impairment and mild Alzheimer disease

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996105

Differential regulation of neurotrophin expression in basal forebrain astrocytes by neuronal signals

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996105

PTEN regulates Akt kinase activity in hippocampal neurons and increases their sensitivity to glutamate and apoptosis

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996105

PTEN in neural precursor cells: regulation of migration, apoptosis, and proliferation

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996105

Pten regulates neuronal soma size: a mouse model of Lhermitte-Duclos disease

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996105

Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996105

CEP-1347 (KT7515), an inhibitor of JNK activation, rescues sympathetic neurons and neuronally differentiated PC12 cells from death evoked by three distinct insults

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21084616

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Neurotrophins induce death of hippocampal neurons via the p75 receptor

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21084616

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1523/JNEUROSCI.2581-10.2010

1 reference

1 August 2017

1 reference

1 August 2017

1 reference