(Q44352367)

2 December 2017

title

PTEN regulates Akt kinase activity in hippocampal neurons and increases their sensitivity to glutamate and apoptosis (English)

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2 December 2017

2

Mark P Mattson

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2 December 2017

Devin S Gary

1

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2 December 2017

publication date

1 January 2002

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2 December 2017

published in

NeuroMolecular Medicine

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2 December 2017

volume

2

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2 December 2017

issue

3

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2 December 2017

page(s)

261-269

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https://scigraph.springernature.com/pub.10.1385/nmm:2:3:261

2 December 2017

exact match

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cites work

Integrin signaling via the PI3-kinase-Akt pathway increases neuronal resistance to glutamate-induced apoptosis

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12 December 2020

Neuronal apoptosis after CNS injury: the roles of glutamate and calcium.

1 reference

12 December 2020

Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo.

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12 December 2020

A role for nuclear PTEN in neuronal differentiation.

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12 December 2020

Regulation of neuronal survival by the serine-threonine protein kinase Akt

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12 December 2020

The PTEN/MMAC1 tumor suppressor induces cell death that is rescued by the AKT/protein kinase B oncogene

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12 December 2020

The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus. Implications for PTEN stability to proteasome-mediated degradation

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12 December 2020

Neurotransmitters in the regulation of neuronal cytoarchitecture

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12 December 2020

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

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12 December 2020

Concentration- and cell type-specific effects of calbindin D28k on vulnerability of hippocampal neurons to seizure-induced injury

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12 December 2020

Basic FGF regulates the expression of a functional 71 kDa NMDA receptor protein that mediates calcium influx and neurotoxicity in hippocampal neurons

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12 December 2020

The multiple roles of PTEN in tumor suppression

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12 December 2020

Expression of LKB1 and PTEN tumor suppressor genes during mouse embryonic development.

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12 December 2020

Regulation of PTEN expression in neuronal apoptosis

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12 December 2020

Overexpression of GDNF induces and maintains hyperinnervation of muscle fibers and multiple end-plate formation

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12 December 2020

Pten regulates neuronal soma size: a mouse model of Lhermitte-Duclos disease

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12 December 2020

Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome

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12 December 2020

Cellular survival: a play in three Akts

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12 December 2020

The PTEN/MMAC1/TEP tumor suppressor gene decreases cell growth and induces apoptosis and anoikis in breast cancer cells

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12 December 2020

Evidence of phosphorylation of Akt and neuronal survival after transient focal cerebral ischemia in mice

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12 December 2020

Akt/protein kinase B up-regulates Bcl-2 expression through cAMP-response element-binding protein.

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12 December 2020

Excitotoxicity and neurodegeneration in amyotrophic lateral sclerosis.

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12 December 2020

NT-3 and BDNF protect CNS neurons against metabolic/excitotoxic insults

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12 December 2020

Impaired Fas response and autoimmunity in Pten+/- mice

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12 December 2020

The role of excitotoxicity in neurodegenerative disease: implications for therapy

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12 December 2020

Tumor suppressor PTEN inhibition of cell invasion, migration, and growth: differential involvement of focal adhesion kinase and p130Cas.

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12 December 2020

Apoptosis in neurodegenerative disorders

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12 December 2020

Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease

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12 December 2020

Phosphatidylinositol 3-kinase and Akt protein kinase are necessary and sufficient for the survival of nerve growth factor-dependent sympathetic neurons.

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12 December 2020

Excitotoxicity and selective neuronal loss in epilepsy

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12 December 2020

Activation of Akt/protein kinase B contributes to induction of ischemic tolerance in the CA1 subfield of gerbil hippocampus

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12 December 2020

Essential role for integrin linked kinase in Akt-mediated integrin survival signaling in hippocampal neurons

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12 December 2020

Regulation of Akt/PKB activity, cellular growth, and apoptosis in prostate carcinoma cells by MMAC/PTEN

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12 December 2020

Germline PTEN mutations in Cowden syndrome-like families.

1 reference

12 December 2020

Brain-derived neurotrophic factor mediates an excitoprotective effect of dietary restriction in mice

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12 December 2020

Akt, a target of phosphatidylinositol 3-kinase, inhibits apoptosis in a differentiating neuronal cell line

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12 December 2020

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

1 reference

12 December 2020

Interactions between entorhinal axons and target hippocampal neurons: a role for glutamate in the development of hippocampal circuitry

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12 December 2020

Germline mutations in PTEN are present in Bannayan-Zonana syndrome

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12 December 2020

Identifiers

DOI

10.1385/NMM:2:3:261

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Dimensions Publication ID

2 December 2017

1002906629

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