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English
PTEN is destabilized by phosphorylation on Thr366.
scientific article published on August 2007
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
2267318
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17444818%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
title
PTEN is destabilized by phosphorylation on Thr366
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
2267318
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17444818%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
main subject
phosphorylation
1 reference
based on heuristic
inferred from title
author
Nick R. Leslie
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
2267318
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17444818%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
author name string
Helene Maccario
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
2267318
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17444818%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
Nevin M Perera
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
2267318
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17444818%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
Lindsay Davidson
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
2267318
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17444818%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
C Peter Downes
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
2267318
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17444818%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
language of work or name
English
0 references
publication date
1 August 2007
1 reference
stated in
Europe PubMed Central
PMC publication ID
2267318
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17444818%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
published in
Biochemical Journal
1 reference
stated in
Europe PubMed Central
PMC publication ID
2267318
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17444818%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
volume
405
1 reference
stated in
Europe PubMed Central
PMC publication ID
2267318
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17444818%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
issue
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
2267318
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17444818%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
page(s)
439-444
1 reference
stated in
Europe PubMed Central
PMC publication ID
2267318
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17444818%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
cites work
NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267318
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22 September 2017
A novel leptin signalling pathway via PTEN inhibition in hypothalamic cell lines and pancreatic beta-cells
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PubMed Central
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22 September 2017
Tumor suppressor PTEN acts through dynamic interaction with the plasma membrane
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267318
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22 September 2017
Casein kinase Iepsilon down-regulates phospho-Akt via PTEN, following genotoxic stress-induced apoptosis in hematopoietic cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267318
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22 September 2017
Cooperative phosphorylation of the tumor suppressor phosphatase and tensin homologue (PTEN) by casein kinases and glycogen synthase kinase 3beta
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267318
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22 September 2017
Genetic analysis of Pten and Tsc2 functional interactions in the mouse reveals asymmetrical haploinsufficiency in tumor suppression
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267318
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22 September 2017
Regulation of PTEN by Rho small GTPases
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267318
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22 September 2017
Exploitation of KESTREL to identify NDRG family members as physiological substrates for SGK1 and GSK3
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PubMed Central
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22 September 2017
Regulation of PTEN phosphorylation and stability by a tumor suppressor candidate protein.
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PubMed Central
reference URL
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22 September 2017
The biology and clinical relevance of the PTEN tumor suppressor pathway
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267318
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22 September 2017
Human cancer, PTEN and the PI-3 kinase pathway
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267318
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22 September 2017
PTEN function: how normal cells control it and tumour cells lose it
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267318
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22 September 2017
Pten dose dictates cancer progression in the prostate
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267318
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22 September 2017
PTEN: from pathology to biology
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267318
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22 September 2017
Membrane-binding and activation mechanism of PTEN.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267318
retrieved
22 September 2017
Zinc-induced PTEN protein degradation through the proteasome pathway in human airway epithelial cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267318
retrieved
22 September 2017
Interfacial kinetic analysis of the tumour suppressor phosphatase, PTEN: evidence for activation by anionic phospholipids
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267318
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22 September 2017
Direct identification of PTEN phosphorylation sites
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267318
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22 September 2017
PTEN mutational spectra, expression levels, and subcellular localization in microsatellite stable and unstable colorectal cancers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267318
retrieved
22 September 2017
Phosphorylation of the PTEN tail acts as an inhibitory switch by preventing its recruitment into a protein complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267318
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22 September 2017
GSK3 takes centre stage more than 20 years after its discovery
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267318
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22 September 2017
Haploinsufficiency of the Pten tumor suppressor gene promotes prostate cancer progression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267318
retrieved
22 September 2017
Targeting mutants of PTEN reveal distinct subsets of tumour suppressor functions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267318
retrieved
22 September 2017
PTEN and myotubularin: novel phosphoinositide phosphatases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267318
retrieved
22 September 2017
The tumor suppressor PTEN is phosphorylated by the protein kinase CK2 at its C terminus. Implications for PTEN stability to proteasome-mediated degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267318
retrieved
22 September 2017
Phosphorylation of the PTEN tail regulates protein stability and function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267318
retrieved
22 September 2017
Mutational spectra of PTEN/MMAC1 gene: a tumor suppressor with lipid phosphatase activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267318
retrieved
22 September 2017
Inactivation of the tumor suppressor PTEN/MMAC1 in advanced human prostate cancer through loss of expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267318
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22 September 2017
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267318
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22 September 2017
Mechanism of activation of protein kinase B by insulin and IGF-1
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267318
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22 September 2017
Negative feedback regulation of the tumor suppressor PTEN by phosphoinositide-induced serine phosphorylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267318
retrieved
25 September 2017
Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267318
retrieved
20 August 2018
Cilostazol prevents tumor necrosis factor-alpha-induced cell death by suppression of phosphatase and tensin homolog deleted from chromosome 10 phosphorylation and activation of Akt/cyclic AMP response element-binding protein phosphorylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267318
retrieved
20 August 2018
Regulation of PTEN binding to MAGI-2 by two putative phosphorylation sites at threonine 382 and 383.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267318
retrieved
20 August 2018
PTEN promoter is methylated in a proportion of invasive breast cancers
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/17444818
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Impaired Fas response and autoimmunity in Pten+/- mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/17444818
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Significance of PTEN alterations in endometrial carcinoma: a population-based study of mutations, promoter methylation and PTEN protein expression
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/17444818
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1042/BJ20061837
1 reference
stated in
Europe PubMed Central
PMC publication ID
2267318
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17444818%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
PMC publication ID
2267318
1 reference
stated in
Europe PubMed Central
PMC publication ID
2267318
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17444818%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
PubMed publication ID
17444818
1 reference
stated in
Europe PubMed Central
PMC publication ID
2267318
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17444818%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
ResearchGate publication ID
6383615
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