(Q38047052)

27 August 2017

title

PGE(2)-driven induction and maintenance of cancer-associated myeloid-derived suppressor cells (English)

1 reference

27 August 2017

4

Kunle Odunsi

0 references

Nataša Obermajer

series ordinal

1

object named as

Nataša Obermajer

1 reference

27 August 2017

5

Kirsten Moysich

1 reference

27 August 2017

Jeffrey L Wong

2

1 reference

27 August 2017

Robert P Edwards

series ordinal

3

1 reference

27 August 2017

Pawel Kalinski

series ordinal

6

1 reference

27 August 2017

publication date

1 January 2012

1 reference

Immunological Investigations

27 August 2017

published in

1 reference

27 August 2017

volume

41

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27 August 2017

issue

6-7

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27 August 2017

page(s)

635-657

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Prostaglandin E2 induces FOXP3 gene expression and T regulatory cell function in human CD4+ T cells

27 August 2017

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A two-step induction of indoleamine 2,3 dioxygenase (IDO) activity during dendritic-cell maturation

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Macrophages programmed by apoptotic cells promote angiogenesis via prostaglandin E2.

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IL-4-induced arginase 1 suppresses alloreactive T cells in tumor-bearing mice

21 January 2018

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Regulation of immune responses by L-arginine metabolism

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Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

21 January 2018

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The interplay between indoleamine 2,3-dioxygenase 1 (IDO1) and cyclooxygenase (COX)-2 in chronic inflammation and cancer

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IL-6 switches the differentiation of monocytes from dendritic cells to macrophages

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21 January 2018

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HIF-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment

21 January 2018

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Mechanism regulating reactive oxygen species in tumor-induced myeloid-derived suppressor cells

21 January 2018

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Thioredoxin-1 modulates transcription of cyclooxygenase-2 via hypoxia-inducible factor-1alpha in non-small cell lung cancer

21 January 2018

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Blockade of B7-H1 improves myeloid dendritic cell–mediated antitumor immunity

21 January 2018

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Role of prostaglandin E2 in peptidoglycan mediated iNOS expression in mouse peritoneal macrophages in vitro

21 January 2018

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MyD88-dependent expansion of an immature GR-1(+)CD11b(+) population induces T cell suppression and Th2 polarization in sepsis

21 January 2018

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Mammary tumor heterogeneity in the expansion of myeloid-derived suppressor cells.

21 January 2018

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EP2 prostanoid receptor promotes squamous cell carcinoma growth through epidermal growth factor receptor transactivation and iNOS and ERK1/2 pathways

21 January 2018

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Nitric oxide and thiol redox regulation of Janus kinase activity

21 January 2018

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Induction of COX-2 by LPS in macrophages is regulated by Tpl2-dependent CREB activation signals.

21 January 2018

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IL-1β regulates a novel myeloid-derived suppressor cell subset that impairs NK cell development and function.

21 January 2018

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Pivotal Advance: Tumor-mediated induction of myeloid-derived suppressor cells and M2-polarized macrophages by altering intracellular PGE₂ catabolism in myeloid cells.

21 January 2018

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https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Aberrant PGE2 metabolism in bladder tumor microenvironment promotes immunosuppressive phenotype of tumor-infiltrating myeloid cells

21 January 2018

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https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Altered expression of 15-hydroxyprostaglandin dehydrogenase in tumor-infiltrated CD11b myeloid cells: a mechanism for immune evasion in cancer.

21 January 2018

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https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Prostaglandin E(2) regulates the level and stability of cyclooxygenase-2 mRNA through activation of p38 mitogen-activated protein kinase in interleukin-1 beta-treated human synovial fibroblasts.

21 January 2018

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Phosphorylation of glycogen synthase kinase-3 and stimulation of T-cell factor signaling following activation of EP2 and EP4 prostanoid receptors by prostaglandin E2.

21 January 2018

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Prostaglandin E2 induced functional expression of early growth response factor-1 by EP4, but not EP2, prostanoid receptors via the phosphatidylinositol 3-kinase and extracellular signal-regulated kinases

21 January 2018

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https://api.crossref.org/works/10.3109%2F08820139.2012.695417

COX-2 Blockade Suppresses Gliomagenesis by Inhibiting Myeloid-Derived Suppressor Cells

21 January 2018

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https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Mechanisms and functional significance of tumour-induced dendritic-cell defects

21 January 2018

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https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Myeloid-derived suppressor cells as regulators of the immune system

21 January 2018

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https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Mechanism of prostaglandin (PG)E2-induced prolactin expression in human T cells: cooperation of two PGE2 receptor subtypes, E-prostanoid (EP) 3 and EP4, via calcium- and cyclic adenosine 5'-monophosphate-mediated signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Regulation of the immune response by prostaglandins

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Cycloxygenase-2 inhibition augments the efficacy of a cancer vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Short-term dietary administration of celecoxib enhances the efficacy of tumor lysate-pulsed dendritic cell vaccines in treating murine breast cancer

21 January 2018

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https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Hypoxia--a key regulatory factor in tumour growth

21 January 2018

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https://api.crossref.org/works/10.3109%2F08820139.2012.695417

A new population of myeloid-derived suppressor cells in hepatocellular carcinoma patients induces CD4(+)CD25(+)Foxp3(+) T cells

21 January 2018

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https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Myeloid derived suppressor cells inhibit natural killer cells in patients with hepatocellular carcinoma via the NKp30 receptor.

21 January 2018

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https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Prostaglandin E2 (PGE2) suppresses natural killer cell function primarily through the PGE2 receptor EP4

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Gr-1+CD115+ Immature Myeloid Suppressor Cells Mediate the Development of Tumor-Induced T Regulatory Cells and T-Cell Anergy in Tumor-Bearing Host

21 January 2018

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https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Regulation of immune responses by prostaglandin E2

21 January 2018

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https://api.crossref.org/works/10.3109%2F08820139.2012.695417

T-cell priming by type-1 and type-2 polarized dendritic cells: the concept of a third signal

21 January 2018

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Indoleamine 2,3-dioxygenase in T-cell tolerance and tumoral immune escape.

21 January 2018

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https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity

21 January 2018

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https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Tumor-associated CD8+ T cell tolerance induced by bone marrow-derived immature myeloid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

The immune tolerance of cancer is mediated by IDO that is inhibited by COX-2 inhibitors through regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Cancer-expanded myeloid-derived suppressor cells induce anergy of NK cells through membrane-bound TGF-beta 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

B7-H1 on myeloid-derived suppressor cells in immune suppression by a mouse model of ovarian cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Fas-induced caspase denitrosylation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Myeloid suppressor lines inhibit T cell responses by an NO-dependent mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

IDO expression by dendritic cells: tolerance and tryptophan catabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

HGF/Met signalling promotes PGE(2) biogenesis via regulation of COX-2 and 15-PGDH expression in colorectal cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Targeting the mechanisms of tumoral immune tolerance with small-molecule inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Distinct myeloid suppressor cell subsets correlate with plasma IL-6 and IL-10 and reduced interferon-alpha signaling in CD4+ T cells from patients with GI malignancy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Indoleamine 2,3-dioxygenase and tumor-induced tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Inhibition of T cell proliferation by macrophage tryptophan catabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

The role of myeloid cells in the promotion of tumour angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Hyperactivation of STAT3 is involved in abnormal differentiation of dendritic cells in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Regulation of dendritic cell differentiation and antitumor immune response in cancer by pharmacologic-selective inhibition of the janus-activated kinase 2/signal transducers and activators of transcription 3 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Positive feedback between PGE2 and COX2 redirects the differentiation of human dendritic cells toward stable myeloid-derived suppressor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

PGE(2)-induced CXCL12 production and CXCR4 expression controls the accumulation of human MDSCs in ovarian cancer environment

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Arginase, prostaglandins, and myeloid-derived suppressor cells in renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

SOCS3 drives proteasomal degradation of indoleamine 2,3-dioxygenase (IDO) and antagonizes IDO-dependent tolerogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Myeloid-derived suppressor cells: more mechanisms for inhibiting antitumor immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Induction of indoleamine 2,3-dioxygenase: a mechanism of the antitumor activity of interferon gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Immune stimulatory receptor CD40 is required for T-cell suppression and T regulatory cell activation mediated by myeloid-derived suppressor cells in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Reversion of immune tolerance in advanced malignancy: modulation of myeloid-derived suppressor cell development by blockade of stem-cell factor function

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Myeloid-derived suppressor cell heterogeneity and subset definition.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Immune escape as a fundamental trait of cancer: focus on IDO.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Towards a genetic definition of cancer-associated inflammation: role of the IDO pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Myeloid-derived suppressor cell accumulation and function in patients with newly diagnosed glioblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Arginase I-producing myeloid-derived suppressor cells in renal cell carcinoma are a subpopulation of activated granulocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Arginase I in myeloid suppressor cells is induced by COX-2 in lung carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Arginine regulation by myeloid derived suppressor cells and tolerance in cancer: mechanisms and therapeutic perspectives

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Arginase I production in the tumor microenvironment by mature myeloid cells inhibits T-cell receptor expression and antigen-specific T-cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

L-arginine consumption by macrophages modulates the expression of CD3 zeta chain in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

COX-2 is induced by HGF stimulation in Met-positive thyroid papillary carcinoma cells and is involved in tumour invasiveness.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Hypoxia induces cyclooxygenase-2 via the NF-kappaB p65 transcription factor in human vascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Targeting HIF-1 for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Editorial: PGE2-producing MDSC: a role in tumor progression?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Phosphodiesterase-5 inhibition augments endogenous antitumor immunity by reducing myeloid-derived suppressor cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Myeloid-derived suppressor cells promote cross-tolerance in B-cell lymphoma by expanding regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Tumor cyclooxygenase-2/prostaglandin E2-dependent promotion of FOXP3 expression and CD4+ CD25+ T regulatory cell activities in lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Cyclooxygenase 2 inhibition promotes IFN-gamma-dependent enhancement of antitumor responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Signaling pathways involved in cyclooxygenase-2 induction by hepatocyte growth factor in non small-cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Reduction of myeloid-derived suppressor cells and induction of M1 macrophages facilitate the rejection of established metastatic disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Prostaglandins, but not tumor-derived IL-10, shut down concomitant tumor-specific CTL responses during murine plasmacytoma progression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Specific inhibition of cyclooxygenase 2 restores antitumor reactivity by altering the balance of IL-10 and IL-12 synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Receptor desensitization and blockade of the suppressive effects of prostaglandin E2 and adenosine on the cytotoxic activity of human melanoma-infiltrating T lymphocytes

21 January 2018

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https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Cyclooxygenase 2: a molecular target for cancer prevention and treatment

21 January 2018

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https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Prostaglandin catabolizing enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

PGE2-mediated upregulation of iNOS in murine breast cancer cells through the activation of EP4 receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Combined spatial and enzymatic regulation of Csk by cAMP and protein kinase a inhibits T cell receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

COX-2 inhibition improves immunotherapy and is associated with decreased numbers of myeloid-derived suppressor cells in mesothelioma. Celecoxib influences MDSC function

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

CD25 and indoleamine 2,3-dioxygenase are up-regulated by prostaglandin E2 and expressed by tumor-associated dendritic cells in vivo: additional mechanisms of T-cell inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Immunosuppressive CD14+HLA-DRlow/- monocytes in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Superoxide and peroxynitrite generation from inducible nitric oxide synthase in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Indoleamine 2,3-dioxygenase in lung dendritic cells promotes Th2 responses and allergic inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

IDO: a double-edged sword for T(H)1/T(H)2 regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Prostaglandin E2 Suppresses NK Activity In Vivo and Promotes Postoperative Tumor Metastasis in Rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

CD80 in immune suppression by mouse ovarian carcinoma-associated Gr-1+CD11b+ myeloid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Subsets of myeloid-derived suppressor cells in tumor-bearing mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08820139.2012.695417

10.3109/08820139.2012.695417

21 January 2018

Identifiers

DOI

1 reference

27 August 2017

1 reference