(Q38049970)

27 August 2017

title

Xenograft models of chronic lymphocytic leukemia: problems, pitfalls and future directions (English)

1 reference

chronic lymphocytic leukemia

27 August 2017

0 references

1 reference

1 reference

2

C Scielzo

1 reference

27 August 2017

P Ghia

6

0 references

author name string

M T S Bertilaccio

1

1 reference

27 August 2017

G Simonetti

3

1 reference

27 August 2017

E Ten Hacken

4

1 reference

27 August 2017

B Apollonio

5

1 reference

27 August 2017

F Caligaris-Cappio

7

1 reference

27 August 2017

publication date

13 September 2012

1 reference

27 August 2017

1 reference

27 August 2017

volume

27

1 reference

27 August 2017

issue

3

1 reference

27 August 2017

page(s)

534-540

1 reference

Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expression

27 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

The DLEU2/miR-15a/16-1 cluster controls B cell proliferation and its deletion leads to chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

A severe combined immunodeficiency mutation in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

Modelling human leukemia and lymphoma in severe combined immunodeficient (SCID) mice: practical applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

Immunodeficient mouse models of lymphoid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

RAG-1-deficient mice have no mature B and T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

NOD/SCID/gamma(c)(null) mouse: an excellent recipient mouse model for engraftment of human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

Myelodysplastic syndromes: the complexity of stem-cell diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

A novel adoptive transfer model of chronic lymphocytic leukemia suggests a key role for T lymphocytes in the disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

Chronic B cell malignancies and bone marrow microenvironment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

Association of an increased frequency of CD14+ HLA-DR lo/neg monocytes with decreased time to progression in chronic lymphocytic leukaemia (CLL).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

Self-renewing hematopoietic stem cell is the primary target in pathogenesis of human chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

DNA profiling and cytogenetic analysis of cell line WSU-CLL reveal cross-contamination with cell line REH (pre B-ALL)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

Antitumour effects of single or combined monoclonal antibodies directed against membrane antigens expressed by human B cells leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

Tumorigenicity of human lymphoblastoid cell lines, acquired during in vitro culture and associated with chromosome gains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

Inhibition of human B-cell chronic lymphocytic leukemia by a monoclonal antibody in xenograft models

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

Establishment and characterization of the tumors of chronic lymphocytic leukemia cell line in nude and SCID mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

MEC1 and MEC2: two new cell lines derived from B-chronic lymphocytic leukaemia in prolymphocytoid transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

Establishment of a novel human B-CLL-like xenograft model in nude mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

A novel Rag2-/-gammac-/--xenograft model of human CLL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

HS1 has a central role in the trafficking and homing of leukemic B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

In vitro and in vivo model of a novel immunotherapy approach for chronic lymphocytic leukemia by anti-CD23 chimeric antigen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

miR-15 and miR-16 induce apoptosis by targeting BCL2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

The microenvironment in mature B-cell malignancies: a target for new treatment strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

Chronic lymphocytic leukemia B cells are endowed with the capacity to attract CD4+, CD40L+ T cells by producing CCL22

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

Adhesion to bone marrow stroma inhibits apoptosis of chronic lymphocytic leukemia cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

Gene expression profiling of B cell chronic lymphocytic leukemia reveals a homogeneous phenotype related to memory B cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

B cell chronic lymphocytic leukemia: lessons learned from studies of the B cell antigen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

Multiple distinct sets of stereotyped antigen receptors indicate a role for antigen in promoting chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

Chronic lymphocytic leukemias utilizing the VH3-21 gene display highly restricted Vlambda2-14 gene use and homologous CDR3s: implicating recognition of a common antigen epitope.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

V(H)3-21 gene usage in chronic lymphocytic leukemia--characterization of a new subgroup with distinct molecular features and poor survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

Over 20% of patients with chronic lymphocytic leukemia carry stereotyped receptors: Pathogenetic implications and clinical correlations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

B-cell receptor signaling in chronic lymphocytic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

The B-cell receptor signaling pathway as a therapeutic target in CLL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

Chronic lymphocytic leukemia: an update on biology and treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

New insights into the pathogenesis of chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

A different ontogenesis for chronic lymphocytic leukemia cases carrying stereotyped antigen receptors: molecular and computational evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

Enhanced human cell engraftment in mice deficient in RAG2 and the common cytokine receptor gamma chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

Absence of Thymus in a Mouse Mutant

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

One Hundred and Twenty-Seven Cultured Human Tumor Cell Lines Producing Tumors in Nude Mice23

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

7 January 2021

‘Nude’, a new hairless gene with pleiotropic effects in the mouse

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

7 January 2021

Xenotransplantation of human lymphoid malignancies is optimized in mice with multiple immunologic defects

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

7 January 2021

A novel nonobese diabetic/severe combined immunodeficient xenograft model for chronic lymphocytic leukemia reflects important clinical characteristics of the disease

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

7 January 2021

Investigating the role of CD38 and functionally related molecular risk factors in the CLL NOD/SCID xenograft model

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

7 January 2021

The emergence and establishment of a clonal subline with partial duplication of chromosome 1q from a tumorigenic human chronic lymphocytic leukemic B-cell line

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

7 January 2021

Pharmacokinetics, biodistribution and tumor localization of two anti-human B-cell chronic lymphocytic leukemia monoclonal antibodies and their F(ab)'2 fragments in a xenograft model

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

7 January 2021

CD38 expression in chronic lymphocytic leukemia is regulated by the tumor microenvironment

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2012.268

7 January 2021

Identifiers

DOI

10.1038/LEU.2012.268

1 reference

Dimensions Publication ID

27 August 2017

1025388220

0 references

1 reference