(Q38052316)

27 August 2017

title

Myocardial substrate metabolism in obesity (English)

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27 August 2017

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O J Rider

1

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27 August 2017

P Cox

2

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27 August 2017

D Tyler

3

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27 August 2017

K Clarke

4

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27 August 2017

S Neubauer

5

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27 August 2017

language of work or name

English

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publication date

16 October 2012

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International Journal of Obesity

27 August 2017

published in

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27 August 2017

volume

37

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27 August 2017

issue

7

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27 August 2017

page(s)

972-979

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https://scigraph.springernature.com/pub.10.1038/ijo.2012.170

27 August 2017

exact match

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cites work

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Energy metabolism in the normal and failing heart: potential for therapeutic interventions

21 January 2018

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The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus

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Measuring mitochondrial function in intact cardiac myocytes

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Metabolic mechanisms in heart failure

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Substrate utilization and glycolysis in the heart

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Obesity and the risk of heart failure

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Comparison of right and left ventricular function in obese and nonobese men.

21 January 2018

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https://api.crossref.org/works/10.1038%2FIJO.2012.170

Beneficial cardiovascular effects of bariatric surgical and dietary weight loss in obesity

21 January 2018

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https://api.crossref.org/works/10.1038%2FIJO.2012.170

Outcome of heart failure with preserved ejection fraction in a population-based study

21 January 2018

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https://api.crossref.org/works/10.1038%2FIJO.2012.170

Role of changes in cardiac metabolism in development of diabetic cardiomyopathy

21 January 2018

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https://api.crossref.org/works/10.1038%2FIJO.2012.170

Overweight, obesity, and mortality in a large prospective cohort of persons 50 to 71 years old.

21 January 2018

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https://api.crossref.org/works/10.1038%2FIJO.2012.170

Regulation of myocardial carbohydrate metabolism under normal and ischaemic conditions. Potential for pharmacological interventions

21 January 2018

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Myocardial substrate metabolism in the normal and failing heart

21 January 2018

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https://api.crossref.org/works/10.1038%2FIJO.2012.170

Effects of acute hyperglycemia on myocardial glycolytic activity in humans

21 January 2018

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https://api.crossref.org/works/10.1038%2FIJO.2012.170

Linking gene expression to function: metabolic flexibility in the normal and diseased heart

21 January 2018

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https://api.crossref.org/works/10.1038%2FIJO.2012.170

Regional myocardial free fatty acid extraction in normal and ischemic myocardium.

21 January 2018

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https://api.crossref.org/works/10.1038%2FIJO.2012.170

Plasma fatty acid levels in infants and adults after myocardial ischemia.

21 January 2018

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https://api.crossref.org/works/10.1038%2FIJO.2012.170

Cardiac fatty acid uptake and transport in health and disease

21 January 2018

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https://api.crossref.org/works/10.1038%2FIJO.2012.170

Regulation of hepatic fatty acid oxidation and ketone body production

21 January 2018

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https://api.crossref.org/works/10.1038%2FIJO.2012.170

Thematic review series: patient-oriented research. Free fatty acid metabolism in human obesity

21 January 2018

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https://api.crossref.org/works/10.1038%2FIJO.2012.170

Effect of obesity and insulin resistance on myocardial substrate metabolism and efficiency in young women

21 January 2018

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https://api.crossref.org/works/10.1038%2FIJO.2012.170

Reduced mitochondrial oxidative capacity and increased mitochondrial uncoupling impair myocardial energetics in obesity

21 January 2018

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https://api.crossref.org/works/10.1038%2FIJO.2012.170

Control of the redox state of the nicotinamide-adenine dinucleotide couple in rat liver cytoplasm

21 January 2018

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https://api.crossref.org/works/10.1038%2FIJO.2012.170

Equilibrium relations between the cytoplasmic adenine nucleotide system and nicotinamide-adenine nucleotide system in rat liver

21 January 2018

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https://api.crossref.org/works/10.1038%2FIJO.2012.170

The redox state of free nicotinamide-adenine dinucleotide phosphate in the cytoplasm of rat liver

21 January 2018

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https://api.crossref.org/works/10.1038%2FIJO.2012.170

The energetics of ion distribution: the origin of the resting electric potential of cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FIJO.2012.170

Equilibrium relations between the oxidation-reduction reactions and the adenosine triphosphate synthesis in suspensions of isolated liver cells

21 January 2018

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The therapeutic implications of ketone bodies: the effects of ketone bodies in pathological conditions: ketosis, ketogenic diet, redox states, insulin resistance, and mitochondrial metabolism

21 January 2018

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https://api.crossref.org/works/10.1038%2FIJO.2012.170

Ketone bodies, potential therapeutic uses

21 January 2018

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https://api.crossref.org/works/10.1038%2FIJO.2012.170

The Randle cycle revisited: a new head for an old hat.

21 January 2018

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https://api.crossref.org/works/10.1038%2FIJO.2012.170

F1-ATPase is a highly efficient molecular motor that rotates with discrete 120 degree steps

21 January 2018

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https://api.crossref.org/works/10.1038%2FIJO.2012.170

A high fat diet increases mitochondrial fatty acid oxidation and uncoupling to decrease efficiency in rat heart

21 January 2018

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https://api.crossref.org/works/10.1038%2FIJO.2012.170

Myocardial fatty acid metabolism in health and disease

21 January 2018

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https://api.crossref.org/works/10.1038%2FIJO.2012.170

Impact of gender on the myocardial metabolic response to obesity.

21 January 2018

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Western diet, but not high fat diet, causes derangements of fatty acid metabolism and contractile dysfunction in the heart of Wistar rats

21 January 2018

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Uncoupling proteins in human heart

21 January 2018

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https://api.crossref.org/works/10.1038%2FIJO.2012.170

Mitochondrial energetics in the heart in obesity-related diabetes: direct evidence for increased uncoupled respiration and activation of uncoupling proteins.

21 January 2018

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https://api.crossref.org/works/10.1038%2FIJO.2012.170

Determining the in vivo regulation of cardiac pyruvate dehydrogenase based on label flux from hyperpolarised [1-13C]pyruvate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

In vivo assessment of pyruvate dehydrogenase flux in the heart using hyperpolarized carbon-13 magnetic resonance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

Validation of the in vivo assessment of pyruvate dehydrogenase activity using hyperpolarised 13C MRS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

Surgical caloric restriction ameliorates mitochondrial electron transport dysfunction in obese females.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

Deficiency of subsarcolemmal mitochondria in obesity and type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

Altered skeletal muscle insulin signaling and mitochondrial complex II-III linked activity in adult offspring of obese mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

Muscle mitochondrial oxidative phosphorylation activity, but not content, is altered with abdominal obesity in sedentary men: synergism with changes in insulin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

Metabolic modulation with perhexiline in chronic heart failure: a randomized, controlled trial of short-term use of a novel treatment

21 January 2018

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https://api.crossref.org/works/10.1038%2FIJO.2012.170

A novel partial fatty acid oxidation inhibitor decreases myocardial oxygen consumption and improves cardiac efficiency in demand-induced ischemic heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

Effects of trimetazidine, a partial inhibitor of fatty acid oxidation, on ventricular function and survival after myocardial infarction and reperfusion in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

Proton magnetic resonance spectroscopy can detect creatine depletion associated with the progression of heart failure in cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

Energetic correlates of cardiac failure: changes in the creatine kinase system in the failing myocardium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

The mechanisms of action of PPARs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

Nuclear receptor signaling and cardiac energetics

21 January 2018

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https://api.crossref.org/works/10.1038%2FIJO.2012.170

Adiponectin: more than just another fat cell hormone?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

PPAR signaling in the control of cardiac energy metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

Expression of putative fatty acid transporter genes are regulated by peroxisome proliferator-activated receptor alpha and gamma activators in a tissue- and inducer-specific manner

21 January 2018

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https://api.crossref.org/works/10.1038%2FIJO.2012.170

Long-term effects of fatty acids on cell viability and gene expression of neonatal cardiac myocytes

21 January 2018

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https://api.crossref.org/works/10.1038%2FIJO.2012.170

Heart lipid accumulation in obese non-diabetic rats: effect of weight loss.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

Cardiac expression of microsomal triglyceride transfer protein is increased in obesity and serves to attenuate cardiac triglyceride accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

A novel mouse model of lipotoxic cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

Adaptation and maladaptation of the heart in diabetes: Part II: potential mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

Adaptation and maladaptation of the heart in diabetes: Part I: general concepts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

A critical role for PPARalpha-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: modulation by dietary fat content.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

Enhanced Sarcolemmal FAT/CD36 Content and Triacylglycerol Storage in Cardiac Myocytes From Obese Zucker Rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

Lipotoxic heart disease in obese rats: implications for human obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

Serum immunoreactive-leptin concentrations in normal-weight and obese humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

Cardiac energy metabolism in obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

Regulation of fatty acid homeostasis in cells: novel role of leptin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

Effect of caloric restriction on myocardial fatty acid uptake, left ventricular mass, and cardiac work in obese adults.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

Myocardial oxygen consumption change predicts left ventricular relaxation improvement in obese humans after weight loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

Bariatric surgery to unload the stressed heart: a metabolic hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

Effects of Catecholamine Stress on Diastolic Function and Myocardial Energetics in Obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

Increased diastolic chamber stiffness during demand ischemia: response to quick length change differentiates rigor-activated from calcium-activated tension

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

7 January 2021

Alterations in left ventricular structure and function in young healthy obese women: assessment by echocardiography and tissue Doppler imaging

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

7 January 2021

Glucose oxidation rates in fatty acid-perfused isolated working hearts from diabetic rats

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

7 January 2021

Clostridium difficile colitis

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

7 January 2021

Effects of moderate hypertension on cardiac function and metabolism in the rabbit

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

7 January 2021

Unloaded heart in vivo replicates fetal gene expression of cardiac hypertrophy

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

7 January 2021

Metabolism of the human heart. II. Studies on fat, ketone and amino acid metabolism

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

7 January 2021

High rates of fatty acid oxidation during reperfusion of ischemic hearts are associated with a decrease in malonyl-CoA levels due to an increase in 5'-AMP-activated protein kinase inhibition of acetyl-CoA carboxylase

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

7 January 2021

Myocardial function and energy substrate metabolism in the insulin-resistant JCR:LA corpulent rat

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

7 January 2021

The determination of the redox states and phosphorylation potential in living tissues and their relationship to metabolic control of disease phenotypes

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

7 January 2021

Equilibrium relations between pyridine nucleotides and adenine nucleotides and their roles in the regulation of metabolic processes

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

7 January 2021

Substrate signaling by insulin: a ketone bodies ratio mimics insulin action in heart

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

7 January 2021

Distribution control of metabolic flux

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

7 January 2021

Myocardial substrate metabolism influences left ventricular energetics in vivo

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

7 January 2021

Mechanisms decreasing glucose oxidation in diabetes and starvation: role of lipid fuels and hormones.

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

7 January 2021

Inhibition of pyruvate kinase by free fatty acids in rat heart muscle

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

7 January 2021

Pyruvate inhibition of pyruvate dehydrogenase kinase. Effects of progressive starvation and hyperthyroidism in vivo, and of dibutyryl cyclic AMP and fatty acids in cultured cardiac myocytes

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

7 January 2021

Effect of chronic CPT-1 inhibition on myocardial ischemia-reperfusion injury (I/R) in a model of diet-induced obesity

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

7 January 2021

Abnormal left ventricular energy metabolism in obese men with preserved systolic and diastolic functions is associated with insulin resistance

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

7 January 2021

The role of the peroxisome proliferator-activated receptor alpha (PPAR alpha) in the control of cardiac lipid metabolism

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

7 January 2021

Fatty acid homeostasis in the normoxic and ischemic heart

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

7 January 2021

Increased rates of fatty acid uptake and plasmalemmal fatty acid transporters in obese Zucker rats

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

7 January 2021

Shedding light on the enigma of myocardial lipotoxicity: the involvement of known and putative regulators of fatty acid storage and mobilization.

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

7 January 2021

Adipose tissue as an endocrine organ

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

7 January 2021

Adiponectin modulates carnitine palmitoyltransferase-1 through AMPK signaling cascade in rat cardiomyocytes

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

7 January 2021

Globular and full-length forms of adiponectin mediate specific changes in glucose and fatty acid uptake and metabolism in cardiomyocytes

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

7 January 2021

Moderate dietary weight loss reduces myocardial steatosis in obese and overweight women

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2012.170

7 January 2021

Identifiers

DOI

10.1038/IJO.2012.170

1 reference

Dimensions Publication ID

27 August 2017

1022396298

0 references

1 reference