(Q38054048)

English

Recognition of viruses in the cytoplasm by RLRs and other helicases--how conformational changes, mitochondrial dynamics and ubiquitination control innate immune responses

scientific article published on 19 October 2012

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

27 August 2017

Recognition of viruses in the cytoplasm by RLRs and other helicases--how conformational changes, mitochondrial dynamics and ubiquitination control innate immune responses (English)

1 reference

Europe PubMed Central

PubMed publication ID

27 August 2017

protein ubiquitination

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Chen Seng Ng

1

1 reference

Europe PubMed Central

PubMed publication ID

27 August 2017

Hiroki Kato

2

1 reference

Europe PubMed Central

PubMed publication ID

27 August 2017

Takashi Fujita

3

1 reference

Europe PubMed Central

PubMed publication ID

27 August 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

19 October 2012

1 reference

Europe PubMed Central

PubMed publication ID

27 August 2017

International Immunology

1 reference

Europe PubMed Central

PubMed publication ID

27 August 2017

24

1 reference

Europe PubMed Central

PubMed publication ID

27 August 2017

12

1 reference

Europe PubMed Central

PubMed publication ID

27 August 2017

739-749

1 reference

Europe PubMed Central

PubMed publication ID

27 August 2017

Approaching the asymptote? Evolution and revolution in immunology

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

Myeloid C-type lectins in innate immunity

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

Pathogen recognition and innate immunity

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

NLR functions in plant and animal immune systems: so far and yet so close

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

TLR-signaling networks: an integration of adaptor molecules, kinases, and cross-talk.

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

Regulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

Control of antiviral defenses through hepatitis C virus disruption of retinoic acid-inducible gene-I signaling

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

Distinct RIG-I and MDA5 Signaling by RNA Viruses in Innate Immunity

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

RIG-I detects viral genomic RNA during negative-strand RNA virus infection

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

Small self-RNA generated by RNase L amplifies antiviral innate immunity

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

Activation of IFN-β expression by a viral mRNA through RNase L and MDA5

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

The C-terminal regulatory domain is the RNA 5'-triphosphate sensor of RIG-I

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

Structural and functional insights into 5′-ppp RNA pattern recognition by the innate immune receptor RIG-I

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

Solution structures of cytosolic RNA sensor MDA5 and LGP2 C-terminal domains: identification of the RNA recognition loop in RIG-I-like receptors

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

Nonself RNA-sensing mechanism of RIG-I helicase and activation of antiviral immune responses

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

Structural Insights into RNA Recognition by RIG-I

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

Structural basis for the activation of innate immune pattern-recognition receptor RIG-I by viral RNA

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

The mitochondrial targeting chaperone 14-3-3ε regulates a RIG-I translocon that mediates membrane association and innate antiviral immunity.

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

RIG-I-like receptors: cytoplasmic sensors for non-self RNA.

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

TRAF6 and MEKK1 play a pivotal role in the RIG-I-like helicase antiviral pathway

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

Regulation of antiviral responses by a direct and specific interaction between TRAF3 and Cardif

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

A FADD-dependent innate immune mechanism in mammalian cells

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

Roles of caspase-8 and caspase-10 in innate immune responses to double-stranded RNA

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

RIG-I RNA helicase activation of IRF3 transcription factor is negatively regulated by caspase-8-mediated cleavage of the RIP1 protein

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

Loss of DExD/H box RNA helicase LGP2 manifests disparate antiviral responses

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

Structure and function of LGP2, a DEX(D/H) helicase that regulates the innate immunity response

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

Regulation of signal transduction by enzymatically inactive antiviral RNA helicase proteins MDA5, RIG-I, and LGP2

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

The complement C1qA enhances retinoic acid-inducible gene-I-mediated immune signalling.

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

Focal adhesion kinase is a component of antiviral RIG-I-like receptor signaling

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

Tom70 mediates activation of interferon regulatory factor 3 on mitochondria

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

Translocase of outer mitochondrial membrane 70 induces interferon response and is impaired by hepatitis C virus NS3.

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

Mitochondrial dynamics regulate the RIG-I-like receptor antiviral pathway

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

Peroxisomes are signaling platforms for antiviral innate immunity

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

Organelle dynamics and dysfunction: A closer link between peroxisomes and mitochondria

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

Mitochondrial-associated endoplasmic reticulum membranes (MAM) form innate immune synapses and are targeted by hepatitis C virus

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

Mitofusin 2 inhibits mitochondrial antiviral signaling

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

Polo-like kinase 1 (PLK1) regulates interferon (IFN) induction by MAVS.

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

PCBP2 mediates degradation of the adaptor MAVS via the HECT ubiquitin ligase AIP4

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

NLRX1 is a regulator of mitochondrial antiviral immunity

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

Inhibition of RIG-I and MDA5-dependent antiviral response by gC1qR at mitochondria

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

Riplet/RNF135, a RING finger protein, ubiquitinates RIG-I to promote interferon-beta induction during the early phase of viral infection

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

The ubiquitin ligase Riplet is essential for RIG-I-dependent innate immune responses to RNA virus infection.

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

REUL is a novel E3 ubiquitin ligase and stimulator of retinoic-acid-inducible gene-I

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

Virus-triggered ubiquitination of TRAF3/6 by cIAP1/2 is essential for induction of interferon-beta (IFN-beta) and cellular antiviral response

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

A functional C-terminal TRAF3-binding site in MAVS participates in positive and negative regulation of the IFN antiviral response

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

TRAF5 is a downstream target of MAVS in antiviral innate immune signaling

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

The tumour suppressor CYLD is a negative regulator of RIG-I-mediated antiviral response

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

Linear ubiquitin assembly complex negatively regulates RIG-I- and TRIM25-mediated type I interferon induction

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

The E3 ubiquitin ligase Triad3A negatively regulates the RIG-I/MAVS signaling pathway by targeting TRAF3 for degradation

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

The ubiquitin ligase RNF5 regulates antiviral responses by mediating degradation of the adaptor protein MITA

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

DEAD/H BOX 3 (DDX3) helicase binds the RIG-I adaptor IPS-1 to up-regulate IFN-beta-inducing potential

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

DDX60, a DEXD/H box helicase, is a novel antiviral factor promoting RIG-I-like receptor-mediated signaling

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

DDX1, DDX21, and DHX36 helicases form a complex with the adaptor molecule TRIF to sense dsRNA in dendritic cells

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

DHX9 pairs with IPS-1 to sense double-stranded RNA in myeloid dendritic cells

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

Aspartate-glutamate-alanine-histidine box motif (DEAH)/RNA helicase A helicases sense microbial DNA in human plasmacytoid dendritic cells

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

Herpes simplex virus type-1 induces IFN-alpha production via Toll-like receptor 9-dependent and -independent pathways

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

DExD/H box RNA helicases: from generic motors to specific dissociation functions

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

Klotho suppresses RIG-I-mediated senescence-associated inflammation.

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

Mutation of the mouse klotho gene leads to a syndrome resembling ageing

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

TRADD Protein Is an Essential Component of the RIG-like Helicase Antiviral Pathway

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXS099

21 January 2018

Identifiers

10.1093/INTIMM/DXS099

1 reference

Europe PubMed Central

PubMed publication ID

27 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

27 August 2017

ResearchGate publication ID

0 references

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