(Q38055065)

27 August 2017

title

Epigenomics and interindividual differences in drug response (English)

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27 August 2017

M Ivanov

1

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27 August 2017

M Kacevska

series ordinal

2

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27 August 2017

M Ingelman-Sundberg

series ordinal

3

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27 August 2017

language of work or name

English

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publication date

24 October 2012

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Clinical Pharmacology & Therapeutics

27 August 2017

published in

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27 August 2017

volume

92

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27 August 2017

issue

6

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27 August 2017

page(s)

727-736

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Pharmacogenomic biomarkers: new tools in current and future drug therapy

27 August 2017

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7 January 2021

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7 January 2021

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7 January 2021

Long noncoding RNA as modular scaffold of histone modification complexes

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7 January 2021

Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

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7 January 2021

Long noncoding RNA, polycomb, and the ghosts haunting INK4b-ARF-INK4a expression

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7 January 2021

ANRIL, a long, noncoding RNA, is an unexpected major hotspot in GWAS.

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7 January 2021

Xist regulation and function explored

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7 January 2021

DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes

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7 January 2021

Promoter targeted small RNAs induce long-term transcriptional gene silencing in human cells

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7 January 2021

Perspectives on epigenetics and its relevance to adverse drug reactions

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7 January 2021

DNA methylation in cancer: too much, but also too little

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7 January 2021

DNA methylation patterns of ulcer-healing genes associated with the normal gastric mucosa of gastric cancers

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7 January 2021

DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific

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7 January 2021

Epigenetic changes to the MDR1 locus in response to chemotherapeutic drugs

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7 January 2021

DNA methylation of the CYP1A1 enhancer is associated with smoking-induced genetic alterations in human lung.

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7 January 2021

Genome-scale methylation analysis of Parkinson's disease patients' brains reveals DNA hypomethylation and increased mRNA expression of cytochrome P450 2E1.

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7 January 2021

Histone deacetylase 1 is required for Carbamazepine-induced CYP3A4 expression.

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7 January 2021

Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer

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7 January 2021

MicroRNA pharmacogenomics: post-transcriptional regulation of drug response

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7 January 2021

Down-regulation of micro-RNA-1 (miR-1) in lung cancer. Suppression of tumorigenic property of lung cancer cells and their sensitization to doxorubicin-induced apoptosis by miR-1

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7 January 2021

MicroRNA-21 in pancreatic cancer: correlation with clinical outcome and pharmacologic aspects underlying its role in the modulation of gemcitabine activity.

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7 January 2021

Identification of microRNA-21 as a biomarker for chemoresistance and clinical outcome following adjuvant therapy in resectable pancreatic cancer

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7 January 2021

Detection of circulating fetal nucleic acids: a review of methods and applications

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7 January 2021

Prospective Study of Quantitation of Plasma DNA Levels in the Diagnosis of Malignant versus Benign Prostate Disease

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7 January 2021

Circulating nucleic acids as a new diagnostic tool

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7 January 2021

Detection of Slit2 promoter hypermethylation in tissue and serum samples from breast cancer patients

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https://api.crossref.org/works/10.1038%2FCLPT.2012.152

7 January 2021

An epigenetic marker panel for detection of lung cancer using cell-free serum DNA.

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https://api.crossref.org/works/10.1038%2FCLPT.2012.152

7 January 2021

Epigenetic markers of prostate cancer in plasma circulating DNA.

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https://api.crossref.org/works/10.1038%2FCLPT.2012.152

7 January 2021

Clinical significance of CDH13 promoter methylation in serum samples from patients with bladder transitional cell carcinoma

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https://api.crossref.org/works/10.1038%2FCLPT.2012.152

7 January 2021

Detection of TFPI2 methylation in the serum of colorectal cancer patients.

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.152

7 January 2021

Methylation patterns in cell-free plasma DNA reflect removal of the primary tumor and drug treatment of breast cancer patients

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.152

7 January 2021

Serum DNA methylation for monitoring response to neoadjuvant chemotherapy in breast cancer patients

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https://api.crossref.org/works/10.1038%2FCLPT.2012.152

7 January 2021

MicroRNAs in body fluids--the mix of hormones and biomarkers

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https://api.crossref.org/works/10.1038%2FCLPT.2012.152

7 January 2021

Multiple paths to a drug resistance phenotype: mutations, translocations, deletions and amplification of coding genes or promoter regions, epigenetic changes and microRNAs

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https://api.crossref.org/works/10.1038%2FCLPT.2012.152

7 January 2021

Epigenetics as a mechanism driving polygenic clinical drug resistance

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7 January 2021

Mechanisms of chemotherapeutic drug resistance in cancer therapy--a quick review

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7 January 2021

Chemotherapeutic drug-induced ABCG2 promoter demethylation as a novel mechanism of acquired multidrug resistance

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7 January 2021

Histone deacetylase inhibitors induce a very broad, pleiotropic anticancer drug resistance phenotype in acute myeloid leukemia cells by modulation of multiple ABC transporter genes

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https://api.crossref.org/works/10.1038%2FCLPT.2012.152

7 January 2021

The histone deacetylase inhibitor trichostatin A downregulates human MDR1 (ABCB1) gene expression by a transcription-dependent mechanism in a drug-resistant small cell lung carcinoma cell line model.

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https://api.crossref.org/works/10.1038%2FCLPT.2012.152

7 January 2021

Role of ERCC1 promoter hypermethylation in drug resistance to cisplatin in human gliomas

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https://api.crossref.org/works/10.1038%2FCLPT.2012.152

7 January 2021

Alterations of microRNAs in cisplatin-resistant human non-small cell lung cancer cells (A549/DDP).

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https://api.crossref.org/works/10.1038%2FCLPT.2012.152

7 January 2021

miR-497 modulates multidrug resistance of human cancer cell lines by targeting BCL2.

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https://api.crossref.org/works/10.1038%2FCLPT.2012.152

7 January 2021

Epigenetic regulation in estrogen receptor positive breast cancer--role in treatment response

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https://api.crossref.org/works/10.1038%2FCLPT.2012.152

7 January 2021

Association of breast cancer DNA methylation profiles with hormone receptor status and response to tamoxifen.

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https://api.crossref.org/works/10.1038%2FCLPT.2012.152

7 January 2021

Circulating tumor-specific DNA: a marker for monitoring efficacy of adjuvant therapy in cancer patients

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.152

7 January 2021

Identification of CDK10 as an important determinant of resistance to endocrine therapy for breast cancer

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.152

7 January 2021

Identification of hypermethylated genes associated with cisplatin resistance in human cancers

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.152

7 January 2021

Global analysis of DNA methylation by Methyl-Capture sequencing reveals epigenetic control of cisplatin resistance in ovarian cancer cell

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.152

7 January 2021

An integrative genomic analysis revealed the relevance of microRNA and gene expression for drug-resistance in human breast cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.152

7 January 2021

A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.152

7 January 2021

Histone modifying enzymes: structures, mechanisms, and specificities

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.152

7 January 2021

Epigenetic-based therapies in cancer: progress to date

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.152

7 January 2021

Adding a Lysine Mimic in the Design of Potent Inhibitors of Histone Lysine Methyltransferases

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.152

7 January 2021

Selective killing of mixed lineage leukemia cells by a potent small-molecule DOT1L inhibitor.

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.152

7 January 2021

Inhibitors of histone demethylases

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.152

7 January 2021

Histone acetyl transferases as emerging drug targets.

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.152

7 January 2021

Drug discovery targeting epigenetic codes: the great potential of UHRF1, which links DNA methylation and histone modifications, as a drug target in cancers and toxoplasmosis.

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.152

7 January 2021

Suppression of inflammation by a synthetic histone mimic

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.152

7 January 2021

Selective inhibition of BET bromodomains

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.152

7 January 2021

Targeting MYC dependence in cancer by inhibiting BET bromodomains

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.152

7 January 2021

Identification of preferential target sites for human DNA methyltransferases

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.152

7 January 2021

Inhibition of DNA methylation by antisense oligonucleotide MG98 as cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FCLPT.2012.152

7 January 2021

Identifiers

DOI

10.1038/CLPT.2012.152

1 reference

Dimensions Publication ID

27 August 2017

1016553570

0 references

1 reference