(Q28242111)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16723399%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

title

Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16723399%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

1 reference

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16723399%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Montse Sanchez-Cespedes

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16723399%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Maria-Jesus Artiga

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16723399%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Antoni Castells

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16723399%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Manel Esteller

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16723399%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

14

Vilhelm A Bohr

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16723399%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

author name string

Ruben Agrelo

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16723399%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Wen-Hsing Cheng

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16723399%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Fernando Setien

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16723399%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Santiago Ropero

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16723399%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Mario F Fraga

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16723399%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Michel Herranz

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16723399%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Maria F Paz

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16723399%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

David Guerrero

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16723399%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Cayetano von Kobbe

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16723399%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

language of work or name

English

0 references

publication date

24 May 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16723399%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

28 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16723399%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

volume

103

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16723399%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

page(s)

8822-8827

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16723399%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

issue

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16723399%20AND%20SRC:MED&resulttype=core&format=json

The Werner syndrome helicase and exonuclease cooperate to resolve telomeric D loops in a manner regulated by TRF1 and TRF2

28 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466544

Candidate tumor-suppressor genes on chromosome arm 8p in early-onset and high-grade breast cancers

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466544

LMNA mutations in atypical Werner's syndrome

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466544

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466544

Werner syndrome: genetic and molecular basis of a premature aging disorder

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466544

p53 Modulates the exonuclease activity of Werner syndrome protein

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466544

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466544

p53-mediated apoptosis is attenuated in Werner syndrome cells

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466544

The Werner syndrome protein is a DNA helicase

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466544

A deletion within the murine Werner syndrome helicase induces sensitivity to inhibitors of topoisomerase and loss of cellular proliferative capacity

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466544

Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466544

The history of cancer epigenetics

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466544

Gene silencing in cancer in association with promoter hypermethylation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466544

RecQ helicases: caretakers of the genome

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466544

Cancer epigenetics comes of age

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466544

Positional cloning of the Werner's syndrome gene

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466544

Redundancy of DNA helicases in p53-mediated apoptosis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466544

Elevated telomere-telomere recombination in WRN-deficient, telomere dysfunctional cells promotes escape from senescence and engagement of the ALT pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466544

Epigenetic loss of the familial tumor-suppressor gene exostosin-1 (EXT1) disrupts heparan sulfate synthesis in cancer cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466544

Highly penetrant hereditary cancer syndromes.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466544

Camptothecin sensitivity in Werner syndrome fibroblasts as assessed by the COMET technique

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466544

A report of two cases of Werner's syndrome and review of the literature

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466544

Werner syndrome and the function of the Werner protein; what they can teach us about the molecular aging process.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466544

p14ARF silencing by promoter hypermethylation mediates abnormal intracellular localization of MDM2.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466544

Werner's syndrome cell lines are hypersensitive to camptothecin-induced chromosomal damage

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466544

Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466544

Werner syndrome lymphoblastoid cells are sensitive to camptothecin-induced apoptosis in S-phase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466544

The premature ageing syndrome protein, WRN, is a 3'-->5' exonuclease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466544

Differential effects of cytotoxic drugs on mortal and immortalized B-lymphoblastoid cell lines from normal and Werner's syndrome patients

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466544

Aging and cancer: issues of basic and clinical science

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466544

DNA helicase activity in Werner's syndrome gene product synthesized in a baculovirus system

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466544

Mutations in the consensus helicase domains of the Werner syndrome gene. Werner's Syndrome Collaborative Group

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466544

Werner syndrome and biological ageing: a molecular genetic hypothesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466544

Werner's syndrome: a review of recent research with an analysis of connective tissue metabolism, growth control of cultured cells, and chromosomal aberrations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466544

Werner's syndrome a review of its symptomatology, natural history, pathologic features, genetics and relationship to the natural aging process

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1466544

A Review of its Symptomatology, Natural History, Pathologic Features, Genetics And Relationship to the Natural Aging Process

29 September 2017

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0600645103

Human Genome and Diseases: A new series of reviews in CMLS Werner Syndrome: genetic and molecular basis of a premature aging disorder

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0600645103

Inactivation of the lamin A/C gene by CpG island promoter hypermethylation in hematologic malignancies, and its association with poor survival in nodal diffuse large B-cell lymphoma.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0600645103

Analysis of helicase gene mutations in Japanese Werner's syndrome patients

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16723399

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Impaired nuclear localization of defective DNA helicases in Werner's syndrome

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16723399

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Two novel regions of interstitial deletion on chromosome 8p in colorectal cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16723399

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0600645103

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16723399%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

ADS bibcode

2006PNAS..103.8822A

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16723399%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

2 references