(Q38055199)

27 August 2017

title

Evaluation of drug-induced injury and human response in precision-cut tissue slices (English)

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27 August 2017

Alison E M Vickers

1

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27 August 2017

Robyn L Fisher

series ordinal

2

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27 August 2017

language of work or name

English

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publication date

25 October 2012

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27 August 2017

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27 August 2017

volume

43

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27 August 2017

issue

1

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27 August 2017

page(s)

29-40

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Mitochondrial glutathione transferases involving a new function for membrane permeability transition pore regulation

27 August 2017

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Apoptosis-inducing factor modulates mitochondrial oxidant stress in acetaminophen hepatotoxicity

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Liver tissue engineering in the evaluation of drug safety

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Cisplatin ototoxicity: involvement of iron and enhanced formation of superoxide anion radicals

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Role of galectin-3 in acetaminophen-induced hepatotoxicity and inflammatory mediator production

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Chemical toxicology: reactive intermediates and their role in pharmacology and toxicology

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Inhibition of mitochondrial beta-oxidation as a mechanism of hepatotoxicity

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Mechanism of acetaminophen oxidation by the peroxidase-like activity of methemoglobin.

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Dapsone-induced hemolytic anemia: effect of N-hydroxy dapsone on the sulfhydryl status and membrane proteins of rat erythrocytes

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21 January 2018

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Oxidant stress, mitochondria, and cell death mechanisms in drug-induced liver injury: lessons learned from acetaminophen hepatotoxicity

21 January 2018

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Thyroid toxicants: assessing reproductive health effects

21 January 2018

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3D cell culture opens new dimensions in cell-based assays

21 January 2018

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A comprehensive listing of bioactivation pathways of organic functional groups

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Effects of thyroglobulin and pendrin on iodide flux through the thyrocyte

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Fingerprinting of cytochrome P450 and microsomal epoxide hydrolase gene expression in human blood cells

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Macrophages and inflammatory mediators in chemical toxicity: a battle of forces

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Three-dimensional culture models of normal and malignant breast epithelial cells

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Interspecies differences in susceptibility to perturbation of thyroid homeostasis: a case study with perchlorate

21 January 2018

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The acclumulation of 35 S-antithyroid drugs by the thyroid gland.

21 January 2018

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The mechanism underlying acetaminophen-induced hepatotoxicity in humans and mice involves mitochondrial damage and nuclear DNA fragmentation

21 January 2018

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Myeloperoxidase catalysed cooxidative metabolism of methimazole: oxidation of glutathione and NADH by free radical intermediates

21 January 2018

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Hepatic failure and lactic acidosis due to fialuridine (FIAU), an investigational nucleoside analogue for chronic hepatitis B.

21 January 2018

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Lipids versus proteins as major targets of pro-oxidant, direct-acting hemolytic agents

21 January 2018

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Tissue repair: an important determinant of final outcome of toxicant-induced injury

21 January 2018

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Histological organization in hepatocyte organoid cultures

21 January 2018

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Drug-induced hematologic syndromes

21 January 2018

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Effect of antithyroid agents 6-propyl-2-thiouracil and 1-mehtyl-2-mercaptoimidazole on human thyroid iodine peroxidase

21 January 2018

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Comparison of methimazole and propylthiouracil in patients with hyperthyroidism caused by Graves' disease

21 January 2018

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Mechanism of action of thioureylene antithyroid drugs: factors affecting intrathyroidal metabolism of propylthiouracil and methimazole in rats

21 January 2018

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21 January 2018

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A comparison of apoptosis and necrosis induced by hepatotoxins in HepG2 cells.

21 January 2018

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Cyclosporine A--induced oxidative stress in human renal mesangial cells: a role for ERK 1/2 MAPK signaling.

21 January 2018

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https://api.crossref.org/works/10.3109%2F00498254.2012.732714

Mitochondria, oxidative stress and cell death

21 January 2018

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https://api.crossref.org/works/10.3109%2F00498254.2012.732714

The role of metabolic activation in drug-induced hepatotoxicity

21 January 2018

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Oxidative stress caused by mitochondrial calcium overload

21 January 2018

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Hepatotoxicity due to mitochondrial dysfunction

21 January 2018

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Ryanodine receptors in liver.

21 January 2018

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Role of the Kupffer cell in mediating hepatic toxicity and carcinogenesis

21 January 2018

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Bioinorganic chemistry in thyroid gland: effect of antithyroid drugs on peroxidase-catalyzed oxidation and iodination reactions

21 January 2018

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Kinetics of cisplatin binding to cellular DNA and modulations by thiol-blocking agents and thiol drugs

21 January 2018

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The signalling pathway of CaMKII-mediated apoptosis and necrosis in the ischemia/reperfusion injury.

21 January 2018

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Modeling tissue-specific signaling and organ function in three dimensions

21 January 2018

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Mitochondria as a pharmacological target

21 January 2018

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https://api.crossref.org/works/10.3109%2F00498254.2012.732714

Peroxidases: a role in the metabolism and side effects of drugs

21 January 2018

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https://api.crossref.org/works/10.3109%2F00498254.2012.732714

Drug metabolite profiling and elucidation of drug-induced hepatotoxicity

21 January 2018

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https://api.crossref.org/works/10.3109%2F00498254.2012.732714

The importance of glutathione in human disease

21 January 2018

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https://api.crossref.org/works/10.3109%2F00498254.2012.732714

Inhibition of mitochondrial membrane bound-glutathione transferase by mitochondrial permeability transition inhibitors including cyclosporin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.732714

Tissue slices for the evaluation of metabolism-based toxicity with the example of diclofenac.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.732714

Characterization of hepatic mitochondrial injury induced by fatty acid oxidation inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.732714

Kidney slices of human and rat to characterize cisplatin-induced injury on cellular pathways and morphology

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.732714

Glutathione Modulation and Oxidative Stress in Human Liver Slices

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.732714

Blood cell oxidative stress precedes hemolysis in whole blood-liver slice co-cultures of rat, dog, and human tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.732714

Thyroid organotypic rat and human cultures used to investigate drug effects on thyroid function, hormone synthesis and release pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.732714

Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.732714

Aminotransferase elevations in healthy adults receiving 4 grams of acetaminophen daily: a randomized controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.732714

Proteomic identification of potential susceptibility factors in drug-induced liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.732714

Mitochondrial protein targets of thiol-reactive electrophiles

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.732714

Calcium and cell death mechanisms: a perspective from the cell death community

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.732714

Interaction of anti-thyroid drugs with iodine: the isolation of two unusual ionic compounds derived from Se-methimazole

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498254.2012.732714

10.3109/00498254.2012.732714

21 January 2018

Identifiers

DOI

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27 August 2017

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