(Q38056367)

27 August 2017

title

TGF-β signaling in onset and progression of hepatocellular carcinoma (English)

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27 August 2017

author name string

Nadja M Meindl-Beinker

series ordinal

1

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27 August 2017

Koichi Matsuzaki

series ordinal

2

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27 August 2017

Steven Dooley

series ordinal

3

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27 August 2017

language of work or name

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24 October 2012

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27 August 2017

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27 August 2017

volume

30

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27 August 2017

issue

5

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27 August 2017

page(s)

514-523

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Non-Smad TGF-beta signals

27 August 2017

cites work

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Modern pathogenetic concepts of liver fibrosis suggest stellate cells and TGF-beta as major players and therapeutic targets

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Transforming growth factor-β adaptor, β2-spectrin, modulates cyclin dependent kinase 4 to reduce development of hepatocellular cancer

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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RING finger-dependent ubiquitination by PRAJA is dependent on TGF-beta and potentially defines the functional status of the tumor suppressor ELF.

21 January 2018

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Progenitor/stem cells give rise to liver cancer due to aberrant TGF-beta and IL-6 signaling

21 January 2018

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Toll-like receptor 4 mediates synergism between alcohol and HCV in hepatic oncogenesis involving stem cell marker Nanog

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Yes-associated protein (YAP65) interacts with Smad7 and potentiates its inhibitory activity against TGF-beta/Smad signaling

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Inhibition of c-Jun NH2-terminal kinase switches Smad3 signaling from oncogenesis to tumor- suppression in rat hepatocellular carcinoma.

21 January 2018

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Hepatitis B virus X protein shifts human hepatic transforming growth factor (TGF)-beta signaling from tumor suppression to oncogenesis in early chronic hepatitis B.

21 January 2018

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Chronic inflammation associated with hepatitis C virus infection perturbs hepatic transforming growth factor beta signaling, promoting cirrhosis and hepatocellular carcinoma

21 January 2018

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21 January 2018

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The proto-oncoprotein c-Fos negatively regulates hepatocellular tumorigenesis.

21 January 2018

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21 January 2018

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21 January 2018

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ILEI requires oncogenic Ras for the epithelial to mesenchymal transition of hepatocytes and liver carcinoma progression

21 January 2018

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Activated hepatic stellate cells induce tumor progression of neoplastic hepatocytes in a TGF-beta dependent fashion

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Down-regulation of connective tissue growth factor by inhibition of transforming growth factor beta blocks the tumor-stroma cross-talk and tumor progression in hepatocellular carcinoma.

21 January 2018

1 reference

Transforming growth factor-beta gene expression signature in mouse hepatocytes predicts clinical outcome in human cancer

21 January 2018

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Extracellular matrix modulates sensitivity of hepatocytes to fibroblastoid dedifferentiation and transforming growth factor beta-induced apoptosis.

21 January 2018

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21 January 2018

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Distinct role of endocytosis for Smad and non-Smad TGF-β signaling regulation in hepatocytes.

21 January 2018

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Hepatocyte-specific Smad7 expression attenuates TGF-beta-mediated fibrogenesis and protects against liver damage

21 January 2018

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21 January 2018

Identifiers

DOI

10.1159/000341704

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27 August 2017

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