(Q46024086)

18 December 2017

title

Inhibition of c-Jun NH2-terminal kinase switches Smad3 signaling from oncogenesis to tumor- suppression in rat hepatocellular carcinoma. (English)

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18 December 2017

13

Shinji Uemoto

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18 December 2017

Etsuro Hatano

2

object named as

Etsuro Hatano

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18 December 2017

author name string

Hiromitsu Nagata

1

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18 December 2017

Masaharu Tada

3

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18 December 2017

Miki Murata

4

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18 December 2017

Koji Kitamura

5

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18 December 2017

Hiroyuki Asechi

6

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18 December 2017

Masato Narita

7

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18 December 2017

Atsuko Yanagida

8

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18 December 2017

Nobuyuki Tamaki

9

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18 December 2017

Shintaro Yagi

10

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18 December 2017

Iwao Ikai

11

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18 December 2017

Koichi Matsuzaki

12

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18 December 2017

language of work or name

English

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publication date

1 June 2009

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18 December 2017

published in

Hepatology

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18 December 2017

volume

49

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18 December 2017

issue

6

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18 December 2017

page(s)

1944-1953

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18 December 2017

Global cancer statistics, 2002

cites work

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Systematic review: evidence-based management of hepatocellular carcinoma--an updated analysis of randomized controlled trials.

21 January 2018

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A randomized phase III study of doxorubicin versus cisplatin/interferon alpha-2b/doxorubicin/fluorouracil (PIAF) combination chemotherapy for unresectable hepatocellular carcinoma.

21 January 2018

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Locoregional therapies for hepatocellular carcinoma: a critical review from the surgeon's perspective

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Sorafenib in advanced hepatocellular carcinoma

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Autocrine IL-6 signaling: a key event in tumorigenesis?

21 January 2018

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Tumour necrosis factor alpha: a potential target for the therapy of solid tumours.

21 January 2018

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IL-1 is required for tumor invasiveness and angiogenesis

21 January 2018

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Signal transduction by the c-Jun N-terminal kinase (JNK)--from inflammation to development

21 January 2018

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The regulation of AP-1 activity by mitogen-activated protein kinases

21 January 2018

1 reference

Signal transduction by the JNK group of MAP kinases

21 January 2018

1 reference

Liver tumor development. c-Jun antagonizes the proapoptotic activity of p53

21 January 2018

1 reference

IKKbeta couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis

21 January 2018

1 reference

Loss of hepatic NF-kappa B activity enhances chemical hepatocarcinogenesis through sustained c-Jun N-terminal kinase 1 activation

21 January 2018

1 reference

Inhibition of c-Jun-N-terminal-kinase sensitizes tumor cells to CD95-induced apoptosis and induces G2/M cell cycle arrest

21 January 2018

1 reference

c-Jun NH2-terminal kinase pathway is involved in constitutive matrix metalloproteinase-1 expression in a hepatocellular carcinoma-derived cell line.

21 January 2018

1 reference

TGF-beta signaling: positive and negative effects on tumorigenesis

21 January 2018

1 reference

Tumour microenvironment: TGFbeta: the molecular Jekyll and Hyde of cancer

21 January 2018

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TGF-beta signaling in tumor suppression and cancer progression

21 January 2018

1 reference

Reversible Smad-dependent signaling between tumor suppression and oncogenesis

21 January 2018

1 reference

Chronic inflammation associated with hepatitis C virus infection perturbs hepatic transforming growth factor beta signaling, promoting cirrhosis and hepatocellular carcinoma

21 January 2018

1 reference

High volume hydrodynamic injection of plasmid DNA via the hepatic artery results in a high level of gene expression in rat hepatocellular carcinoma induced by diethylnitrosamine

21 January 2018

1 reference

Gefitinib, an EGFR inhibitor, prevents hepatocellular carcinoma development in the rat liver with cirrhosis

21 January 2018

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Doxorubicin coupled to lactosaminated albumin inhibits the growth of hepatocellular carcinomas induced in rats by diethylnitrosamine.

21 January 2018

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CHOP deficiency attenuates cholestasis-induced liver fibrosis by reduction of hepatocyte injury

21 January 2018

1 reference

TGF-beta and HGF transmit the signals through JNK-dependent Smad2/3 phosphorylation at the linker regions

21 January 2018

1 reference

Two-dimensional differential gel electrophoresis/analysis of diethylnitrosamine induced rat hepatocellular carcinoma

21 January 2018

1 reference

Hepatocyte necrosis induced by oxidative stress and IL-1 alpha release mediate carcinogen-induced compensatory proliferation and liver tumorigenesis

21 January 2018

1 reference

Inhibition of Jun NH2-terminal kinases suppresses the growth of experimental head and neck squamous cell carcinoma

21 January 2018

1 reference

c-Jun-N-terminal kinase drives cyclin D1 expression and proliferation during liver regeneration

21 January 2018

1 reference

Regression of abdominal aortic aneurysm by inhibition of c-Jun N-terminal kinase

21 January 2018

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Smoldering and polarized inflammation in the initiation and promotion of malignant disease

21 January 2018

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21 January 2018

Inflammation and cancer

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Cancer-related inflammation

21 January 2018

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High rates of hepatocellular carcinoma in cirrhotic patients with high liver cell proliferative activity.

21 January 2018

1 reference

AP-1 in cell proliferation and survival

21 January 2018

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The selectivity of protein kinase inhibitors: a further update

21 January 2018

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Proliferation of human HCC cells and chemically induced mouse liver cancers requires JNK1-dependent p21 downregulation

21 January 2018

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Novel advancements in the management of hepatocellular carcinoma in 2008.

21 January 2018

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Hepatocellular carcinoma: epidemiology and molecular carcinogenesis

21 January 2018

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Implication of frequent local ablation therapy for intrahepatic recurrence in prolonged survival of patients with hepatocellular carcinoma undergoing hepatic resection: an analysis of 610 patients over 16 years old.

21 January 2018

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Improving survival results after resection of hepatocellular carcinoma: a prospective study of 377 patients over 10 years

21 January 2018

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7 January 2021

Obesity and steatosis influence serum and hepatic inflammatory markers in chronic hepatitis C

1 reference

7 January 2021

Pravastatin reduces lung metastasis of rat hepatocellular carcinoma via a coordinated decrease of MMP expression and activity

1 reference

7 January 2021

A simple micromethod for collagen and total protein determination in formalin-fixed paraffin-embedded sections

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7 January 2021

Cytokine gene expression in liver following minor or major hepatectomy in rat

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7 January 2021

The JNK signal transduction pathway

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7 January 2021

Increased risk of hepatocellular carcinoma development in patients with cirrhosis and with high hepatocellular proliferation

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7 January 2021

Aurora kinase B is a predictive factor for the aggressive recurrence of hepatocellular carcinoma after curative hepatectomy

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7 January 2021

Uracil-tegafur as an adjuvant for hepatocellular carcinoma: a randomized trial

1 reference

7 January 2021

Identifiers

DOI

10.1002/HEP.22860

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18 December 2017

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18 December 2017