(Q38061429)

English

Instruction of myeloid cells by the tumor microenvironment: Open questions on the dynamics and plasticity of different tumor-associated myeloid cell populations.

scientific article published on October 2012

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23170260%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

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Europe PubMed Central

Instruction of myeloid cells by the tumor microenvironment: Open questions on the dynamics and plasticity of different tumor-associated myeloid cell populations (English)

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Europe PubMed Central

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18 February 2020

Jo A Van Ginderachter

3

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18 February 2020

Adelaida Sarukhan

4

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18 February 2020

author name string

Elio Schouppe

1

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18 February 2020

Patrick De Baetselier

2

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18 February 2020

publication date

1 October 2012

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18 February 2020

1 reference

Europe PubMed Central

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18 February 2020

1

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18 February 2020

7

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18 February 2020

1135-1145

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18 February 2020

Imaging tumor-stroma interactions during chemotherapy reveals contributions of the microenvironment to resistance

1 reference

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Marginating dendritic cells of the tumor microenvironment cross-present tumor antigens and stably engage tumor-specific T cells

1 reference

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Coordinated regulation of myeloid cells by tumours

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6 September 2017

Tumor microenvironment complexity: emerging roles in cancer therapy.

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Origins of tumor-associated macrophages and neutrophils.

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Dissecting the autocrine and paracrine roles of the CCR2-CCL2 axis in tumor survival and angiogenesis

1 reference

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Intratumoral injection of CpG oligonucleotides induces the differentiation and reduces the immunosuppressive activity of myeloid-derived suppressor cells

1 reference

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Regulation of immune responses by prostaglandin E2

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6 September 2017

Monocytic CCR2(+) myeloid-derived suppressor cells promote immune escape by limiting activated CD8 T-cell infiltration into the tumor microenvironment

1 reference

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1 reference

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Phenotype, function and clinical implications of myeloid-derived suppressor cells in cancer patients

1 reference

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Regulatory dendritic cells in the tumor immunoenvironment

1 reference

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PGE(2)-induced CXCL12 production and CXCR4 expression controls the accumulation of human MDSCs in ovarian cancer environment

1 reference

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6 September 2017

Tumor stress inside out: cell-extrinsic effects of the unfolded protein response in tumor cells modulate the immunological landscape of the tumor microenvironment

1 reference

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6 September 2017

Protective and pathogenic functions of macrophage subsets

1 reference

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6 September 2017

Chemokine nitration prevents intratumoral infiltration of antigen-specific T cells.

1 reference

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6 September 2017

Prognostic and predictive impact of intra- and peritumoral immune infiltrates

1 reference

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6 September 2017

Transition of tumor-associated macrophages from MHC class II(hi) to MHC class II(low) mediates tumor progression in mice

1 reference

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Mononuclear phagocyte heterogeneity in cancer: different subsets and activation states reaching out at the tumor site

1 reference

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6 September 2017

Exosomes/microvesicles: mediators of cancer-associated immunosuppressive microenvironments

1 reference

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6 September 2017

CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis

1 reference

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6 September 2017

Local macrophage proliferation, rather than recruitment from the blood, is a signature of TH2 inflammation

1 reference

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Dendritic cell-specific intercellular adhesion molecule 3-grabbing non-integrin (DC-SIGN) recognizes a novel ligand, Mac-2-binding protein, characteristically expressed on human colorectal carcinomas

1 reference

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6 September 2017

Rgs2 mediates pro-angiogenic function of myeloid derived suppressor cells in the tumor microenvironment via upregulation of MCP-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494626

6 September 2017

Antigen specificity of immune suppression by myeloid-derived suppressor cells

1 reference

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6 September 2017

Stat3 and MMP7 contribute to pancreatic ductal adenocarcinoma initiation and progression.

1 reference

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6 September 2017

Transmission of endoplasmic reticulum stress and pro-inflammation from tumor cells to myeloid cells

1 reference

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6 September 2017

Tumor-associated neutrophils: new targets for cancer therapy

1 reference

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6 September 2017

Carcinoma-derived interleukin-8 disorients dendritic cell migration without impairing T-cell stimulation

1 reference

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6 September 2017

Myeloid cell population dynamics in healthy and tumor-bearing mice

1 reference

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6 September 2017

The secreted factors responsible for pre-metastatic niche formation: old sayings and new thoughts.

1 reference

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6 September 2017

Exosomes and cancer: a newly described pathway of immune suppression

1 reference

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6 September 2017

Imaging cycling tumor hypoxia.

1 reference

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6 September 2017

The dendritic cell-tumor cross-talk in cancer

1 reference

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6 September 2017

HIF-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494626

6 September 2017

Hypoxia-inducible factor 2alpha regulates macrophage function in mouse models of acute and tumor inflammation

1 reference

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6 September 2017

Neutrophil kinetics in health and disease.

1 reference

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6 September 2017

The polarization of immune cells in the tumour environment by TGFbeta

1 reference

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6 September 2017

Direct and differential suppression of myeloid-derived suppressor cell subsets by sunitinib is compartmentally constrained

1 reference

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6 September 2017

Differential activation and antagonistic function of HIF-{alpha} isoforms in macrophages are essential for NO homeostasis

1 reference

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6 September 2017

Eicosanoids and cancer

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6 September 2017

Macrophages, innate immunity and cancer: balance, tolerance, and diversity

1 reference

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6 September 2017

Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells

1 reference

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6 September 2017

IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion

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Gene expression analysis of macrophages that facilitate tumor invasion supports a role for Wnt-signaling in mediating their activity in primary mammary tumors

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Targeting distinct tumor-infiltrating myeloid cells by inhibiting CSF-1 receptor: combating tumor evasion of antiangiogenic therapy.

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MafB/c-Maf deficiency enables self-renewal of differentiated functional macrophages.

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Polarization of tumor-associated neutrophil phenotype by TGF-beta: "N1" versus "N2" TAN

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6 September 2017

Unwelcome complement

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CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages

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Hypoxia-inducible factors 1 and 2 are important transcriptional effectors in primary macrophages experiencing hypoxia

1 reference

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Myeloid-derived suppressor cells: linking inflammation and cancer

1 reference

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6 September 2017

Induction of myeloid-derived suppressor cells by tumor exosomes

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6 September 2017

Myeloid-derived suppressor cells as regulators of the immune system

1 reference

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Inflammatory signals in dendritic cell activation and the induction of adaptive immunity

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1 reference

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6 September 2017

Subsets of myeloid-derived suppressor cells in tumor-bearing mice

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The role of myeloid cells in the promotion of tumour angiogenesis

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Plasticity in tumor-promoting inflammation: impairment of macrophage recruitment evokes a compensatory neutrophil response

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Altered macrophage differentiation and immune dysfunction in tumor development

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6 September 2017

S100A8 and S100A9 in inflammation and cancer

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6 September 2017

Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response

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6 September 2017

Distinct role of macrophages in different tumor microenvironments

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6 September 2017

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6 September 2017

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6 September 2017

The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages

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6 September 2017

Inhibition of tumor progression by suppression of stress protein GRP78/BiP induction in fibrosarcoma B/C10ME.

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6 September 2017

Vascular endothelial growth factor-induced skin carcinogenesis depends on recruitment and alternative activation of macrophages

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6 September 2017

Angiopoietin 2 stimulates TIE2-expressing monocytes to suppress T cell activation and to promote regulatory T cell expansion.

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14 September 2017

Heat shock protein 27 differentiates tolerogenic macrophages that may support human breast cancer progression.

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14 September 2017

Tumor Cell-Released TLR4 Ligands Stimulate Gr-1+CD11b+F4/80+ Cells to Induce Apoptosis of Activated T Cells

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14 September 2017

Hierarchy of immunosuppressive strength among myeloid-derived suppressor cell subsets is determined by GM-CSF.

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14 September 2017

Tumor-educated tolerogenic dendritic cells induce CD3epsilon down-regulation and apoptosis of T cells through oxygen-dependent pathways

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14 September 2017

Chemokine-mediated rapid turnover of myeloid-derived suppressor cells in tumor-bearing mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494626

14 September 2017

Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494626

14 September 2017

Tumor exosomes inhibit differentiation of bone marrow dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494626

14 September 2017

Tumor-derived hyaluronan induces formation of immunosuppressive macrophages through transient early activation of monocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494626

14 September 2017

Human tumor-released microvesicles promote the differentiation of myeloid cells with transforming growth factor-beta-mediated suppressive activity on T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494626

14 September 2017

Proteomic analysis of dendritic cell-derived exosomes: a secreted subcellular compartment distinct from apoptotic vesicles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494626

28 September 2017

Origin and Functions of Tumor-Associated Myeloid Cells (TAMCs).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494626

23 June 2018

Non-small cell lung cancer cyclooxygenase-2-dependent regulation of cytokine balance in lymphocytes and macrophages: up-regulation of interleukin 10 and down-regulation of interleukin 12 production.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494626

23 June 2018

Nanobody-based targeting of the macrophage mannose receptor for effective in vivo imaging of tumor-associated macrophages.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494626

31 August 2018

Immunostimulatory conventional dendritic cells evolve into regulatory macrophage-like cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494626

31 August 2018

Targeting the ANG2/TIE2 axis inhibits tumor growth and metastasis by impairing angiogenesis and disabling rebounds of proangiogenic myeloid cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494626

31 August 2018

CXCL17 and ICAM2 are associated with a potential anti-tumor immune response in early intraepithelial stages of human pancreatic carcinogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494626

31 August 2018

From skin dendritic cells to a simplified classification of human and mouse dendritic cell subsets.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494626

31 August 2018

Angiopoietin-2 regulates gene expression in TIE2-expressing monocytes and augments their inherent proangiogenic functions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494626

31 August 2018

Tumor-educated CD11bhighIalow regulatory dendritic cells suppress T cell response through arginase I.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494626

31 August 2018

A distinguishing gene signature shared by tumor-infiltrating Tie2-expressing monocytes, blood "resident" monocytes, and embryonic macrophages suggests common functions and developmental relationships

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494626

31 August 2018

Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494626

31 August 2018

Inhibition of the differentiation of dendritic cells from CD34(+) progenitors by tumor cells: role of interleukin-6 and macrophage colony-stimulating factor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3494626

31 August 2018

Divergent effects of hypoxia on dendritic cell functions

1 reference

https://api.crossref.org/works/10.4161%2FONCI.21566

21 January 2018

Targeting Tumor Antigens to Secreted Membrane Vesicles In vivo Induces Efficient Antitumor Immune Responses

1 reference

https://api.crossref.org/works/10.4161%2FONCI.21566

21 January 2018

Hypoxia prolongs neutrophil survival in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/23170260

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Different tumor microenvironments contain functionally distinct subsets of macrophages derived from Ly6C(high) monocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/23170260

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD99 plays a major role in the migration of monocytes through endothelial junctions

1 reference

https://pubmed.ncbi.nlm.nih.gov/23170260

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxisome proliferator-activated receptor gamma (PPARgamma) ligands reverse CTL suppression by alternatively activated (M2) macrophages in cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/23170260

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-10 prevents the differentiation of monocytes to dendritic cells but promotes their maturation to macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/23170260

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Significance of M2-polarized tumor-associated macrophage in pancreatic cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/23170260

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitric Oxide-Independent CTL Suppression during Tumor Progression: Association with Arginase-Producing (M2) Myeloid Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23170260

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane vesicles shed by murine melanoma cells selectively inhibit the expression of Ia antigen by macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/23170260

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The parallel lives of angiogenesis and immunosuppression: cancer and other tales

1 reference

https://pubmed.ncbi.nlm.nih.gov/23170260

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of the cell-binding domain of fibronectin with VLA-5 integrin induces monokine production in cultured human monocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/23170260

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Significance of macrophage chemoattractant protein-1 in macrophage recruitment, angiogenesis, and survival in human breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/23170260

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of the macrophage content of neoplasms by chemoattractants

1 reference

https://pubmed.ncbi.nlm.nih.gov/23170260

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4161/ONCI.21566

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23170260%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23170260%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23170260%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

ResearchGate publication ID

0 references

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