(Q38061858)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23175229%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

review article

1 reference

title

NLRC5: a key regulator of MHC class I-dependent immune responses (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23175229%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

author

Peter J Van den Elsen

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23175229%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

1

Koichi S Kobayashi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23175229%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

publication date

1 December 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23175229%20AND%20SRC:MED&resulttype=core&format=json

Nature Reviews Immunology

18 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23175229%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

volume

12

1 reference

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18 February 2020

issue

12

1 reference

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18 February 2020

page(s)

813-820

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Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome)

18 February 2020

cites work

1 reference

Genetic control of MHC class II expression

21 January 2018

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The RFX complex is crucial for the constitutive and CIITA-mediated transactivation of MHC class I and beta2-microglobulin genes

21 January 2018

1 reference

Induction of MHC class I expression by the MHC class II transactivator CIITA.

21 January 2018

1 reference

Regulation of class I major histocompatibility complex (MHC) by nucleotide-binding domain, leucine-rich repeat-containing (NLR) proteins

21 January 2018

1 reference

NLR family member NLRC5 is a transcriptional regulator of MHC class I genes

21 January 2018

1 reference

NLRC5 cooperates with the RFX transcription factor complex to induce MHC class I gene expression.

21 January 2018

1 reference

NLRC5 deficiency selectively impairs MHC class I- dependent lymphocyte killing by cytotoxic T cells

21 January 2018

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NLRC5 controls basal MHC class I gene expression in an MHC enhanceosome-dependent manner

21 January 2018

1 reference

Cutting edge: impaired MHC class I expression in mice deficient for Nlrc5/class I transactivator

21 January 2018

1 reference

Enhanced TLR-induced NF-κB signaling and type I interferon responses in NLRC5 deficient mice

21 January 2018

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NLRC5 regulates MHC class I antigen presentation in host defense against intracellular pathogens

21 January 2018

1 reference

Regulation of major histocompatibility complex class II genes

21 January 2018

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Expression regulation of major histocompatibility complex class I and class II encoding genes

21 January 2018

1 reference

Congenital immunodeficiency with a regulatory defect in MHC class II gene expression lacks a specific HLA-DR promoter binding protein, RF-X.

21 January 2018

1 reference

A novel DNA-binding regulatory factor is mutated in primary MHC class II deficiency (bare lymphocyte syndrome)

21 January 2018

1 reference

A gene encoding a novel RFX-associated transactivator is mutated in the majority of MHC class II deficiency patients

21 January 2018

1 reference

RFX-B is the gene responsible for the most common cause of the bare lymphocyte syndrome, an MHC class II immunodeficiency

21 January 2018

1 reference

RFXAP, a novel subunit of the RFX DNA binding complex is mutated in MHC class II deficiency

21 January 2018

1 reference

MHC class II enhanceosome: how is the class II transactivator recruited to DNA-bound activators?

21 January 2018

1 reference

Residual MHC class II expression on mature dendritic cells and activated B cells in RFX5-deficient mice.

21 January 2018

1 reference

Identification of CIITA regulated genetic module dedicated for antigen presentation.

21 January 2018

1 reference

Class II transactivator and class II MHC gene expression in microglia: modulation by the cytokines TGF-beta, IL-4, IL-13 and IL-10.

21 January 2018

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Expression of MHC class II molecules in different cellular and functional compartments is controlled by differential usage of multiple promoters of the transactivator CIITA.

21 January 2018

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The nucleotide-binding oligomerization domain-like receptor NLRC5 is involved in IFN-dependent antiviral immune responses

21 January 2018

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A role for the human nucleotide-binding domain, leucine-rich repeat-containing family member NLRC5 in antiviral responses

21 January 2018

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NLRC5 limits the activation of inflammatory pathways

21 January 2018

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NLRs join TLRs as innate sensors of pathogens

21 January 2018

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Acetylation by PCAF enhances CIITA nuclear accumulation and transactivation of major histocompatibility complex class II genes

21 January 2018

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Mechanisms of nuclear import and export that control the subcellular localization of class II transactivator

21 January 2018

1 reference

The nucleotide-binding domain of NLRC5 is critical for nuclear import and transactivation activity

21 January 2018

1 reference

The S box of major histocompatibility complex class II promoters is a key determinant for recruitment of the transcriptional co-activator CIITA.

21 January 2018

1 reference

Transcriptional scaffold: CIITA interacts with NF-Y, RFX, and CREB to cause stereospecific regulation of the class II major histocompatibility complex promoter

21 January 2018

1 reference

NLRC5 negatively regulates the NF-kappaB and type I interferon signaling pathways

21 January 2018

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Cutting edge: NLRC5-dependent activation of the inflammasome

21 January 2018

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NLRC5 deficiency does not influence cytokine induction by virus and bacteria infections.

21 January 2018

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NLRC5: a newly discovered MHC class I transactivator (CITA)

21 January 2018

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Dendritic cell-specific MHC class II transactivator contains a caspase recruitment domain that confers potent transactivation activity

21 January 2018

1 reference

Regulation of MHC class II expression by interferon-gamma mediated by the transactivator gene CIITA.

21 January 2018

1 reference

Class II transactivator (CIITA) is sufficient for the inducible expression of major histocompatibility complex class II genes.

21 January 2018

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CIITA stimulation of transcription factor binding to major histocompatibility complex class II and associated promoters in vivo

21 January 2018

1 reference

GTP-dependent recruitment of CIITA to the class II major histocompatibility complex promoter.

21 January 2018

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Mice lacking the MHC class II transactivator (CIITA) show tissue-specific impairment of MHC class II expression

21 January 2018

1 reference

Site alpha is crucial for two routes of IFN gamma-induced MHC class I transactivation: the ISRE-mediated route and a novel pathway involving CIITA

31 March 2020

1 reference

The MHC-specific enhanceosome and its role in MHC class I and beta(2)-microglobulin gene transactivation

31 March 2020

1 reference

Mice lacking the transcription factor CIITA--a second look

31 March 2020

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A defect in the nuclear translocation of CIITA causes a form of type II bare lymphocyte syndrome

31 March 2020

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Activation of the MHC class II transactivator CIITA by interferon-gamma requires cooperative interaction between Stat1 and USF-1

31 March 2020

1 reference

Purified X2 binding protein (X2BP) cooperatively binds the class II MHC X box region in the presence of purified RFX, the X box factor deficient in the bare lymphocyte syndrome

31 March 2020

1 reference

12 December 2020

Reduced IL-4-, lipopolysaccharide-, and IFN-gamma-induced MHC class II expression in mice lacking class II transactivator due to targeted deletion of the GTP-binding domain

1 reference

12 December 2020

CIITA is a transcriptional coactivator that is recruited to MHC class II promoters by multiple synergistic interactions with an enhanceosome complex

1 reference

12 December 2020

Identification of distinct regions of 5' flanking DNA that mediate constitutive, IFN-gamma, STAT1, and TGF-beta-regulated expression of the class II transactivator gene.

1 reference

12 December 2020

Discoordinate expression of invariant chain and MHC class II genes in class II transactivator-transfected fibroblasts defective for RFX5

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRI3339

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23175229%20AND%20SRC:MED&resulttype=core&format=json

18 February 2020

1 reference