(Q38063400)

28 August 2017

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title

Oestrogen-related receptors in breast cancer: control of cellular metabolism and beyond (English)

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28 August 2017

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2

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28 August 2017

Geneviève Deblois

1

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PubMed ID

23192231

28 August 2017

language of work or name

English

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publication date

29 November 2012

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28 August 2017

Nature Reviews Cancer

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28 August 2017

13

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28 August 2017

1

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28 August 2017

27-36

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https://scigraph.springernature.com/pub.10.1038/nrc3396

28 August 2017

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Identification of a new class of steroid hormone receptors

31 March 2020

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The NR3B subgroup: an ovERRview

31 March 2020

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To ERR in the estrogen pathway

31 March 2020

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Transcriptional control of energy homeostasis by the estrogen-related receptors

31 March 2020

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ERRalpha: a metabolic function for the oldest orphan

31 March 2020

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Hormone-independent transcriptional activation and coactivator binding by novel orphan nuclear receptor ERR3

31 March 2020

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31 March 2020

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Constitutive activation of transcription and binding of coactivator by estrogen-related receptors 1 and 2

31 March 2020

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Estrogen receptor-related receptor alpha 1 interacts with coactivator and constitutively activates the estrogen response elements of the human lactoferrin gene.

31 March 2020

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Ncoa3 functions as an essential Esrrb coactivator to sustain embryonic stem cell self-renewal and reprogramming

31 March 2020

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Definition of the molecular basis for estrogen receptor-related receptor-alpha-cofactor interactions

31 March 2020

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Peroxisome proliferator-activated receptor coactivator-1alpha (PGC-1alpha) coactivates the cardiac-enriched nuclear receptors estrogen-related receptor-alpha and -gamma. Identification of novel leucine-rich interaction motif within PGC-1alpha

31 March 2020

1 reference

PPARgamma coactivator 1beta/ERR ligand 1 is an ERR protein ligand, whose expression induces a high-energy expenditure and antagonizes obesity

31 March 2020

1 reference

A polymorphic autoregulatory hormone response element in the human estrogen-related receptor alpha (ERRalpha) promoter dictates peroxisome proliferator-activated receptor gamma coactivator-1alpha control of ERRalpha expression.

31 March 2020

1 reference

The transcriptional coactivator PGC-1 regulates the expression and activity of the orphan nuclear receptor estrogen-related receptor alpha (ERRalpha).

31 March 2020

1 reference

31 March 2020

1 reference

Epidermal growth factor-induced signaling in breast cancer cells results in selective target gene activation by orphan nuclear receptor estrogen-related receptor alpha

31 March 2020

1 reference

Physiological genomics identifies estrogen-related receptor alpha as a regulator of renal sodium and potassium homeostasis and the renin-angiotensin pathway

31 March 2020

1 reference

Phosphorylation-dependent sumoylation regulates estrogen-related receptor-alpha and -gamma transcriptional activity through a synergy control motif

31 March 2020

1 reference

An acetylation switch modulates the transcriptional activity of estrogen-related receptor alpha

31 March 2020

1 reference

Erralpha and Gabpa/b specify PGC-1alpha-dependent oxidative phosphorylation gene expression that is altered in diabetic muscle

31 March 2020

1 reference

The homeobox protein Prox1 is a negative modulator of ERR{alpha}/PGC-1{alpha} bioenergetic functions

31 March 2020

1 reference

Genomic convergence among ERRα, PROX1, and BMAL1 in the control of metabolic clock outputs

31 March 2020

1 reference

Genome-wide orchestration of cardiac functions by the orphan nuclear receptors ERRalpha and gamma.

31 March 2020

1 reference

ERRgamma directs and maintains the transition to oxidative metabolism in the postnatal heart.

31 March 2020

1 reference

Nuclear receptor ERR alpha and coactivator PGC-1 beta are effectors of IFN-gamma-induced host defense

31 March 2020

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31 March 2020

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Reduced fat mass in mice lacking orphan nuclear receptor estrogen-related receptor alpha

31 March 2020

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31 March 2020

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Orphan nuclear receptor estrogen-related receptor alpha is essential for adaptive thermogenesis

31 March 2020

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The nuclear receptor ERRalpha is required for the bioenergetic and functional adaptation to cardiac pressure overload.

31 March 2020

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31 March 2020

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A role for estrogen-related receptor alpha in the control of mitochondrial fatty acid beta-oxidation during brown adipocyte differentiation

31 March 2020

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Human fetal mesenchymal stem cells differentiate into brown and white adipocytes: a role for ERRalpha in human UCP1 expression

31 March 2020

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31 March 2020

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Peroxisome proliferator-activated receptor-gamma coactivator 1-alpha (PGC1alpha) is a metabolic regulator of intestinal epithelial cell fate

31 March 2020

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Placental abnormalities in mouse embryos lacking the orphan nuclear receptor ERR-beta

31 March 2020

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Diethylstilbestrol regulates trophoblast stem cell differentiation as a ligand of orphan nuclear receptor ERR beta

31 March 2020

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31 March 2020

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Dissecting self-renewal in stem cells with RNA interference

31 March 2020

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Reprogramming of fibroblasts into induced pluripotent stem cells with orphan nuclear receptor Esrrb.

31 March 2020

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Integration of external signaling pathways with the core transcriptional network in embryonic stem cells

31 March 2020

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31 March 2020

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Modulation of adipogenesis-related gene expression by estrogen-related receptor gamma during adipocytic differentiation.

31 March 2020

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31 March 2020

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The orphan nuclear receptor estrogen-related receptor alpha is a transcriptional regulator of the human medium-chain acyl coenzyme A dehydrogenase gene.

31 March 2020

1 reference

Genome-wide identification of direct target genes implicates estrogen-related receptor alpha as a determinant of breast cancer heterogeneity.

31 March 2020

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31 March 2020

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31 March 2020

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The significance of the expression of ERRalpha as a potential biomarker in breast cancer

31 March 2020

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31 March 2020

1 reference

The metabolic regulator ERRα, a downstream target of HER2/IGF-1R, as a therapeutic target in breast cancer

31 March 2020

1 reference

31 March 2020

1 reference

ERRgamma mediates tamoxifen resistance in novel models of invasive lobular breast cancer

31 March 2020

1 reference

Modulating estrogen receptor-related receptor-alpha activity inhibits cell proliferation

31 March 2020

1 reference

Transcriptional control of the ERBB2 amplicon by ERRalpha and PGC-1beta promotes mammary gland tumorigenesis

31 March 2020

1 reference

Dual function of ERRα in breast cancer and bone metastasis formation: implication of VEGF and osteoprotegerin

31 March 2020

1 reference

WNT11 expression is induced by estrogen-related receptor alpha and beta-catenin and acts in an autocrine manner to increase cancer cell migration

31 March 2020

1 reference

31 March 2020

1 reference

MiR-137 targets estrogen-related receptor alpha and impairs the proliferative and migratory capacity of breast cancer cells

31 March 2020

1 reference

miR-378(∗) mediates metabolic shift in breast cancer cells via the PGC-1β/ERRγ transcriptional pathway

31 March 2020

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31 March 2020

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Regulation of cancer cell metabolism

31 March 2020

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Otto Warburg's contributions to current concepts of cancer metabolism

31 March 2020

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The Drosophila estrogen-related receptor directs a metabolic switch that supports developmental growth.

31 March 2020

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Metabolic positron emission tomography imaging in cancer detection and therapy response

31 March 2020

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Mitochondrial biogenesis in epithelial cancer cells promotes breast cancer tumor growth and confers autophagy resistance

31 March 2020

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31 March 2020

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Adaptation of energy metabolism in breast cancer brain metastases.

31 March 2020

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Links between metabolism and cancer

31 March 2020

1 reference

The Skp2-SCF E3 ligase regulates Akt ubiquitination, glycolysis, herceptin sensitivity, and tumorigenesis

31 March 2020

1 reference

Upregulation of lactate dehydrogenase A by ErbB2 through heat shock factor 1 promotes breast cancer cell glycolysis and growth.

31 March 2020

1 reference

Fine-tuning the lipogenic/lipolytic balance to optimize the metabolic requirements of cancer cell growth: molecular mechanisms and therapeutic perspectives.

31 March 2020

1 reference

The tyrosine kinase receptor HER2 (erbB-2): from oncogenesis to adipogenesis

31 March 2020

1 reference

PGC-1α promotes the growth of ErbB2/Neu-induced mammary tumors by regulating nutrient supply

31 March 2020

1 reference

Transcriptional amplification in tumor cells with elevated c-Myc.

31 March 2020

1 reference

c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells

31 March 2020

1 reference

METabolic adaptations in the tumor MYCroenvironment

31 March 2020

1 reference

The interplay between MYC and HIF in cancer.

31 March 2020

1 reference

Role of the estrogen receptor coactivator AIB1 (SRC-3) and HER-2/neu in tamoxifen resistance in breast cancer

31 March 2020

1 reference

Regulation of ERBB2 by oestrogen receptor-PAX2 determines response to tamoxifen

31 March 2020

1 reference

Structural basis for the deactivation of the estrogen-related receptor gamma by diethylstilbestrol or 4-hydroxytamoxifen and determinants of selectivity

31 March 2020

1 reference

Crystal structure of human estrogen-related receptor alpha in complex with a synthetic inverse agonist reveals its novel molecular mechanism

31 March 2020

1 reference

X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation

31 March 2020

1 reference

4-Hydroxytamoxifen binds to and deactivates the estrogen-related receptor gamma

31 March 2020

1 reference

Endocrine disruptor bisphenol A strongly binds to human estrogen-related receptor gamma (ERRgamma) with high constitutive activity

31 March 2020

1 reference

Identification of a selective inverse agonist for the orphan nuclear receptor estrogen-related receptor alpha

31 March 2020

1 reference

Structure-guided synthesis of tamoxifen analogs with improved selectivity for the orphan ERRgamma

31 March 2020

1 reference

Identification of an agonist ligand for estrogen-related receptors ERRbeta/gamma.

31 March 2020

1 reference

Identification and structure-activity relationship of phenolic acyl hydrazones as selective agonists for the estrogen-related orphan nuclear receptors ERRbeta and ERRgamma

31 March 2020

1 reference

Identification of diaryl ether-based ligands for estrogen-related receptor α as potential antidiabetic agents

31 March 2020

1 reference

Targeting cancer metabolism: a therapeutic window opens

31 March 2020

1 reference

Recent advance in the design of small molecular modulators of estrogen-related receptors.

31 March 2020

1 reference

Exercise and PGC-1α-independent synchronization of type I muscle metabolism and vasculature by ERRγ.

31 March 2020

1 reference

On respiratory impairment in cancer cells

31 March 2020

1 reference

12 December 2020

4-Hydroxytamoxifen is an isoform-specific inhibitor of orphan estrogen-receptor-related (ERR) nuclear receptors beta and gamma

1 reference

12 December 2020

Transcriptional regulation of the estrogen-inducible pS2 breast cancer marker gene by the ERR family of orphan nuclear receptors

1 reference

12 December 2020

Activation of the osteopontin promoter by the orphan nuclear receptor estrogen receptor related alpha

1 reference

12 December 2020

Regulation of glycolysis and the Warburg effect by estrogen-related receptors

1 reference

12 December 2020

Modulation of aromatase expression in the breast tissue by ERR alpha-1 orphan receptor

1 reference

12 December 2020

1 reference

12 December 2020

Constitutive Activation of Transcription and Binding of Coactivator by Estrogen-Related Receptors 1 and 2

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRC3396

1 reference

PubMed ID

23192231

Dimensions Publication ID

28 August 2017

0 references

1 reference

PubMed ID

23192231