(Q38065938)

28 August 2017

1 reference

title

Themes and variations in ER/SR calcium release channels: structure and function (English)

1 reference

28 August 2017

Peter B Stathopulos

1

1 reference

28 August 2017

Min-duk Seo

2

1 reference

28 August 2017

Masahiro Enomoto

3

1 reference

28 August 2017

Fernando J Amador

4

1 reference

28 August 2017

Noboru Ishiyama

5

1 reference

28 August 2017

Mitsuhiko Ikura

6

1 reference

28 August 2017

publication date

1 December 2012

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28 August 2017

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28 August 2017

volume

27

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28 August 2017

issue

6

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28 August 2017

page(s)

331-342

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Crystal structure of type I ryanodine receptor amino-terminal -trefoil domain reveals a disease-associated mutation"hot spot"loop

28 August 2017

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21 January 2018

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21 January 2018

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21 January 2018

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Ancestral Ca2+ signaling machinery in early animal and fungal evolution

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The relationship between exertional heat illness, exertional rhabdomyolysis, and malignant hyperthermia

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Cloning and expression of human brain type I inositol 1,4,5-trisphosphate 5-phosphatase. High levels of mRNA in cerebellar Purkinje cells

21 January 2018

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Isoform diversity of the inositol trisphosphate receptor in cell types of mouse origin

21 January 2018

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21 January 2018

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21 January 2018

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RyR1 S-nitrosylation underlies environmental heat stroke and sudden death in Y522S RyR1 knockin mice

21 January 2018

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A Missense Mutation in the CASQ2 Gene Is Associated with Autosomal-Recessive Catecholamine-Induced Polymorphic Ventricular Tachycardia

21 January 2018

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Calcium-induced release of calcium from the cardiac sarcoplasmic reticulum

21 January 2018

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Calcium as a coagonist of inositol 1,4,5-trisphosphate-induced calcium release.

21 January 2018

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Inositol trisphosphate receptor Ca2+ release channels.

21 January 2018

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Primary structure and functional expression of the inositol 1,4,5-trisphosphate-binding protein P400.

21 January 2018

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Expression of a ryanodine receptor-Ca2+ channel that is regulated by TGF-beta

21 January 2018

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The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.

21 January 2018

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The role of calsequestrin, triadin, and junctin in conferring cardiac ryanodine receptor responsiveness to luminal calcium

21 January 2018

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Primary structure and distribution of a novel ryanodine receptor/calcium release channel from rabbit brain.

21 January 2018

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Two-state conformational changes in inositol 1,4,5-trisphosphate receptor regulated by calcium

21 January 2018

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Three-dimensional Rearrangements within Inositol 1,4,5-Trisphosphate Receptor by Calcium

21 January 2018

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High prevalence of exercise-induced arrhythmias in catecholaminergic polymorphic ventricular tachycardia mutation-positive family members diagnosed by cascade genetic screening

21 January 2018

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Incidence and risk factors of arrhythmic events in catecholaminergic polymorphic ventricular tachycardia

21 January 2018

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21 January 2018

1 reference

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Inhibition of cardiac Ca2+ release channels (RyR2) determines efficacy of class I antiarrhythmic drugs in catecholaminergic polymorphic ventricular tachycardia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00013.2012

Purified ryanodine receptor of skeletal muscle sarcoplasmic reticulum forms Ca2+-activated oligomeric Ca2+ channels in planar bilayers

21 January 2018

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Molecular basis of the isoform-specific ligand-binding affinity of inositol 1,4,5-trisphosphate receptors

21 January 2018

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Molecular cloning of mouse type 2 and type 3 inositol 1,4,5-trisphosphate receptors and identification of a novel type 2 receptor splice variant.

21 January 2018

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Three-dimensional structure of the type 1 inositol 1,4,5-trisphosphate receptor at 24 A resolution

21 January 2018

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21 January 2018

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21 January 2018

Multi-minicore Disease

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Autosomal recessive inheritance of RYR1 mutations in a congenital myopathy with cores.

21 January 2018

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Genetics and pathogenesis of malignant hyperthermia

21 January 2018

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Parallelization of the MAFFT multiple sequence alignment program

21 January 2018

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Dantrolene, a therapeutic agent for malignant hyperthermia, markedly improves the function of failing cardiomyocytes by stabilizing interdomain interactions within the ryanodine receptor.

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSIOL.00013.2012

Dantrolene--a review of its pharmacology, therapeutic use and new developments

21 January 2018

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Expression of a cardiac Ca(2+)-release channel isoform in mammalian brain

21 January 2018

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Molecular genetics of exercise-induced polymorphic ventricular tachycardia: identification of three novel cardiac ryanodine receptor mutations and two common calsequestrin 2 amino-acid polymorphisms

21 January 2018

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Ryanodine receptor physiology and its role in disease

21 January 2018

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Ryanodine receptors: structure, expression, molecular details, and function in calcium release.

21 January 2018

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Apo and InsP3-bound crystal structures of the ligand-binding domain of an InsP3 receptor

21 January 2018

1 reference

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Calmodulin kinase II inhibition prevents arrhythmias in RyR2(R4496C+/-) mice with catecholaminergic polymorphic ventricular tachycardia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00013.2012

Crystal structures of the N-terminal domains of cardiac and skeletal muscle ryanodine receptors: insights into disease mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00013.2012

The pore structure of the closed RyR1 channel

21 January 2018

1 reference

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Flexible architecture of IP3R1 by Cryo-EM

21 January 2018

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Ryanodine receptor calcium release channels: an evolutionary perspective.

21 January 2018

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Involvement of the cardiac ryanodine receptor/calcium release channel in catecholaminergic polymorphic ventricular tachycardia

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00013.2012

Molecular cloning and characterization of the ryanodine receptor/junctional channel complex cDNA from skeletal muscle sarcoplasmic reticulum

21 January 2018

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unc-68 encodes a ryanodine receptor involved in regulating C. elegans body-wall muscle contraction

21 January 2018

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Cytosolic inositol 1,4,5-trisphosphate dynamics during intracellular calcium oscillations in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00013.2012

The RYR2-encoded ryanodine receptor/calcium release channel in patients diagnosed previously with either catecholaminergic polymorphic ventricular tachycardia or genotype negative, exercise-induced long QT syndrome: a comprehensive open reading [...]

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00013.2012

Putative receptor for inositol 1,4,5-trisphosphate similar to ryanodine receptor

21 January 2018

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The sarcoplasmic Ca2+-ATPase: design of a perfect chemi-osmotic pump

21 January 2018

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Differential Localization of Alternative Spliced Transcripts Encoding Inositol 1,4,5-Trisphosphate Receptors in Mouse Cerebellum and Hippocampus: In Situ Hybridization Study

21 January 2018

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Primary structure and functional expression from cDNA of the cardiac ryanodine receptor/calcium release channel.

21 January 2018

1 reference

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Immunohistochemical localization of ryanodine receptors in mouse central nervous system

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSIOL.00013.2012

Diagnosis and treatment of catecholaminergic polymorphic ventricular tachycardia

21 January 2018

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Malignant hyperthermia: a pharmacogenetic disease of Ca++ regulating proteins

21 January 2018

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Alpha and beta isoforms of ryanodine receptor from chicken skeletal muscle are the homologues of mammalian RyR1 and RyR3.

21 January 2018

1 reference

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[3H]Azidodantrolene: synthesis and use in identification of a putative skeletal muscle dantrolene binding site in sarcoplasmic reticulum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00013.2012

Identification of Dantrolene Binding Sites in Porcine Skeletal Muscle Sarcoplasmic Reticulum

21 January 2018

1 reference

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Mutations in the cardiac ryanodine receptor gene (hRyR2) underlie catecholaminergic polymorphic ventricular tachycardia

21 January 2018

1 reference

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Identification of intracellular and plasma membrane calcium channel homologues in pathogenic parasites

21 January 2018

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Mutations in the ryanodine receptor gene in central core disease and malignant hyperthermia

21 January 2018

1 reference

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Cryo-electron microscopy and three-dimensional reconstruction of the calcium release channel/ryanodine receptor from skeletal muscle

21 January 2018

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Mutations in RYR1 in malignant hyperthermia and central core disease

21 January 2018

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RYR1 mutations causing central core disease are associated with more severe malignant hyperthermia in vitro contracture test phenotypes

21 January 2018

1 reference

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21 January 2018

Malignant hyperthermia

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00013.2012

Three additional inositol 1,4,5-trisphosphate receptors: molecular cloning and differential localization in brain and peripheral tissues

21 January 2018

1 reference

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Synthetic partial agonists reveal key steps in IP3 receptor activation

21 January 2018

1 reference

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Sudden unexplained death in a patient with a family history of malignant hyperthermia

21 January 2018

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Coordinated movement of cytoplasmic and transmembrane domains of RyR1 upon gating

21 January 2018

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Internal structure and visualization of transmembrane domains of the RyR1 calcium release channel by cryo-EM.

21 January 2018

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Inositol 1,4,5-trisphosphate receptor contains multiple cavities and L-shaped ligand-binding domains.

21 January 2018

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Structural and functional conservation of key domains in InsP3 and ryanodine receptors

21 January 2018

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https://api.crossref.org/works/10.1152%2FPHYSIOL.00013.2012

Structure of the type 1 inositol 1,4,5-trisphosphate receptor revealed by electron cryomicroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00013.2012

Electron cryomicroscopy and angular reconstitution used to visualize the skeletal muscle calcium release channel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00013.2012

The spectrum of pathology in central core disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00013.2012

Loss of Inositol 1,4,5-trisphosphate receptors from bile duct epithelia is a common event in cholestasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00013.2012

Mechanistic basis of bell-shaped dependence of inositol 1,4,5-trisphosphate receptor gating on cytosolic calcium

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00013.2012

Mutation-linked defective interdomain interactions within ryanodine receptor cause aberrant Ca²⁺release leading to catecholaminergic polymorphic ventricular tachycardia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00013.2012

Genetic evidence for involvement of type 1, type 2 and type 3 inositol 1,4,5-trisphosphate receptors in signal transduction through the B-cell antigen receptor

21 January 2018

1 reference

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Ubiquitous SPRY domains and their role in the skeletal type ryanodine receptor.

21 January 2018

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Primary structure and expression from complementary DNA of skeletal muscle ryanodine receptor.

21 January 2018

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MEGA5: Molecular Evolutionary Genetics Analysis Using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony Methods

21 January 2018

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Promoter structure and gene expression of the mouse inositol 1,4,5-trisphosphate receptor type 3 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00013.2012

Defective domain-domain interactions within the ryanodine receptor as a critical cause of diastolic Ca2+ leak in failing hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00013.2012

Expression of inositol trisphosphate receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00013.2012

Ca(2+) signalling by IP(3) receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00013.2012

Modulation of SR Ca release by luminal Ca and calsequestrin in cardiac myocytes: effects of CASQ2 mutations linked to sudden cardiac death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00013.2012

The amino-terminal disease hotspot of ryanodine receptors forms a cytoplasmic vestibule

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00013.2012

Flecainide therapy reduces exercise-induced ventricular arrhythmias in patients with catecholaminergic polymorphic ventricular tachycardia

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00013.2012

The Ca2+ pumps of the endoplasmic reticulum and Golgi apparatus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00013.2012

Subcellular distribution of the inositol 1,4,5-trisphosphate receptors: functional relevance and molecular determinants

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00013.2012

Defective cardiac ryanodine receptor regulation during atrial fibrillation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00013.2012

Dantrolene. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in malignant hyperthermia, the neuroleptic malignant syndrome and an update of its use in muscle spasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00013.2012

Flecainide prevents catecholaminergic polymorphic ventricular tachycardia in mice and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00013.2012

Altered function and regulation of cardiac ryanodine receptors in cardiac disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00013.2012

Novel therapeutic approaches for heart failure by normalizing calcium cycling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00013.2012

Tyr-167/Trp-168 in type 1/3 inositol 1,4,5-trisphosphate receptor mediates functional coupling between ligand binding and channel opening

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00013.2012

Mutational analysis of the ligand binding site of the inositol 1,4,5-trisphosphate receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00013.2012

A mutation in the human ryanodine receptor gene associated with central core disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00013.2012

The Deletion of Exon 3 in the Cardiac Ryanodine Receptor Is Rescued by β Strand Switching

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00013.2012

Calcium Induced Release of Calcium from the Sarcoplasmic Reticulum of Skinned Skeletal Muscle Fibres

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00013.2012

10.1152/PHYSIOL.00013.2012

21 January 2018

Identifiers

DOI

1 reference

28 August 2017

1 reference