(Q38066622)

28 August 2017

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title

A practical guide to metabolomic profiling as a discovery tool for human heart disease (English)

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28 August 2017

metabolomic profiling

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4

Julian L Griffin

1 reference

28 August 2017

Lisa C Heather

1

1 reference

PubMed ID

23231771

28 August 2017

Xinzhu Wang

series ordinal

2

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PubMed ID

23231771

28 August 2017

James A West

series ordinal

3

1 reference

28 August 2017

8 December 2012

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Journal of Molecular and Cellular Cardiology

28 August 2017

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28 August 2017

55

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28 August 2017

2-11

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Myocardial utilization of carbohydrate and lipids

28 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Metabolism of the human heart. II. Studies on fat, ketone and amino acid metabolism

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Fatty acid homeostasis in the normoxic and ischemic heart

7 January 2021

1 reference

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Linking gene expression to function: metabolic flexibility in the normal and diseased heart

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Impaired myocardial metabolic reserve and substrate selection flexibility during stress in patients with idiopathic dilated cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Altered myocardial fatty acid and glucose metabolism in idiopathic dilated cardiomyopathy.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Myocardial fatty acid metabolism: independent predictor of left ventricular mass in hypertensive heart disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Changes in cardiac substrate transporters and metabolic proteins mirror the metabolic shift in patients with aortic stenosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Intramyocardial lipid accumulation in the failing human heart resembles the lipotoxic rat heart.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Metabolic gene expression in fetal and failing human heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Uncoupling proteins in human heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Abnormal mitochondrial respiration in failed human myocardium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Dysfunction of mitochondrial respiratory chain complex I in human failing myocardium is not due to disturbed mitochondrial gene expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Detection of low phosphocreatine to ATP ratio in failing hypertrophied human myocardium by 31P magnetic resonance spectroscopy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Myocardial phosphocreatine-to-ATP ratio is a predictor of mortality in patients with dilated cardiomyopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Influence of aging or left ventricular hypertrophy on the human heart: contents of phosphorus metabolites measured by 31P MRS

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Abnormal cardiac and skeletal muscle energy metabolism in patients with type 2 diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Use of metabolomic profiling in the study of arachidonic acid metabolism in cardiovascular disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Metabolomics and cardiovascular biomarker discovery

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Metabolomics as a tool for cardiac research

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

The -omics era: proteomics and lipidomics in vascular research

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Systems level studies of mammalian metabolomes: the roles of mass spectrometry and nuclear magnetic resonance spectroscopy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Metabolic fingerprinting as a diagnostic tool.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

A comprehensive classification system for lipids

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Update of the LIPID MAPS comprehensive classification system for lipids

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

The human serum metabolome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

A comparison of cell and tissue extraction techniques using high-resolution 1H-NMR spectroscopy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Design of experiments: an efficient strategy to identify factors influencing extraction and derivatization of Arabidopsis thaliana samples in metabolomic studies with gas chromatography/mass spectrometry

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

An introduction to biological nuclear magnetic resonance spectroscopy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabonomics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Application of chemometrics to 1H NMR spectroscopic data to investigate a relationship between human serum metabolic profiles and hypertension

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Human metabolic phenotype diversity and its association with diet and blood pressure.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Abnormal lipid profile of dystrophic cardiac tissue as demonstrated by one- and two-dimensional magic-angle spinning (1)H NMR spectroscopy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Characterization of systemic metabolic phenotypes associated with subclinical atherosclerosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Metabolic signatures of insulin resistance in 7,098 young adults

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Metabolic profiling using direct infusion electrospray ionisation mass spectrometry for the characterisation of olive oils

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Metabolic footprinting as a tool for discriminating between brewing yeasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

A combined 1H-NMR spectroscopy- and mass spectrometry-based metabolomic study of the PPAR-alpha null mutant mouse defines profound systemic changes in metabolism linked to the metabolic syndrome.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Closed-loop, multiobjective optimization of two-dimensional gas chromatography/mass spectrometry for serum metabolomics.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

GMD@CSB.DB: the Golm Metabolome Database

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

An NMR-based metabonomic approach to investigate the biochemical consequences of genetic strain differences: application to the C57BL10J and Alpk:ApfCD mouse

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Metabolite profiling for plant functional genomics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

High-throughput classification of yeast mutants for functional genomics using metabolic footprinting.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

The importance of experimental design and QC samples in large-scale and MS-driven untargeted metabolomic studies of humans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Bias as a threat to the validity of cancer molecular-marker research

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Proton NMR analysis of plasma is a weak predictor of coronary artery disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

NMR-based prediction of cardiovascular risk in diabetes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

1H NMR metabonomics approach to the disease continuum of diabetic complications and premature death

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Nuclear magnetic resonance-based metabolomics predicts exercise-induced ischemia in patients with suspected coronary artery disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Improving metabolite knowledge in stable atherosclerosis patients by association and correlation of GC-MS and 1H NMR fingerprints

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Association of a peripheral blood metabolic profile with coronary artery disease and risk of subsequent cardiovascular events

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Metabolomic profiling reveals distinct patterns of myocardial substrate use in humans with coronary artery disease or left ventricular dysfunction during surgical ischemia/reperfusion.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

¹H nuclear magnetic resonance based metabolic urinary profiling of patients with ischemic heart failure.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Proteomic and metabolomic analysis of atrial profibrillatory remodelling in congestive heart failure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Recent highlights of metabolomics in cardiovascular research

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Dietary precursors of trimethylamine in man: a pilot study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Human metabolic individuality in biomedical and pharmaceutical research

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Serum metabolomics reveals many novel metabolic markers of heart failure, including pseudouridine and 2-oxoglutarate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Metabolomic identification of novel biomarkers of myocardial ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Silent myocardial ischemia is associated with altered plasma phospholipids

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Metabolite profiling of blood from individuals undergoing planned myocardial infarction reveals early markers of myocardial injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Combined metabolomic and proteomic analysis of human atrial fibrillation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

Proteomics, metabolomics, and immunomics on microparticles derived from human atherosclerotic plaques

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YJMCC.2012.12.001

10.1016/J.YJMCC.2012.12.001

7 January 2021

Identifiers

DOI

1 reference

28 August 2017

1 reference

PubMed ID

23231771