(Q38068543)

28 August 2017

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title

Patterning and cell fate in the inner ear: a case for Notch in the chicken embryo (English)

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28 August 2017

Joana Neves

1

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28 August 2017

Gina Abelló

series ordinal

2

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28 August 2017

Jelena Petrovic

series ordinal

3

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28 August 2017

Fernando Giraldez

series ordinal

4

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28 August 2017

language of work or name

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17 December 2012

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Development, Growth and Differentiation

28 August 2017

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28 August 2017

55

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28 August 2017

96-112

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28 August 2017

1

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Establishment of a proneural field in the inner ear.

28 August 2017

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Early regionalization of the otic placode and its regulation by the Notch signaling pathway.

21 January 2018

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Independent regulation of Sox3 and Lmx1b by FGF and BMP signaling influences the neurogenic and non-neurogenic domains in the chick otic placode.

21 January 2018

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Eya1-Six1 interaction is sufficient to induce hair cell fate in the cochlea by activating Atoh1 expression in cooperation with Sox2.

21 January 2018

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FGF signaling is required for determination of otic neuroblasts in the chick embryo.

21 January 2018

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Patterning and cell fate in ear development

21 January 2018

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Structural and mechanistic insights into cooperative assembly of dimeric Notch transcription complexes

21 January 2018

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Notch signaling: cell fate control and signal integration in development

21 January 2018

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Proneural function of neurogenic genes in the developing Drosophila eye.

21 January 2018

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Canonical Notch signaling is not necessary for prosensory induction in the mouse cochlea: insights from a conditional mutant of RBPjkappa.

21 January 2018

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Spatial and temporal segregation of auditory and vestibular neurons in the otic placode.

21 January 2018

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The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis

21 January 2018

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Math1: an essential gene for the generation of inner ear hair cells

21 January 2018

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Proneural genes and the specification of neural cell types

21 January 2018

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Standard atlas of the gross anatomy of the developing inner ear of the chicken.

21 January 2018

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Patterning and morphogenesis of the vertebrate inner ear.

21 January 2018

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Transient retinoic acid signaling confers anterior-posterior polarity to the inner ear.

21 January 2018

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The Notch signaling pathway: transcriptional regulation at Notch target genes

21 January 2018

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Notch signalling in Drosophila: three ways to use a pathway

21 January 2018

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Notch signalling: a simple pathway becomes complex

21 January 2018

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21 January 2018

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Notch ligands with contrasting functions: Jagged1 and Delta1 in the mouse inner ear

21 January 2018

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Glycosyltransferase activity of Fringe modulates Notch-Delta interactions.

21 January 2018

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Atoh1 expression defines activated progenitors and differentiating hair cells during avian hair cell regeneration

21 January 2018

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Lateral inhibition in proneural clusters: cis-regulatory logic and default repression by Suppressor of Hairless

21 January 2018

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Notch in the pathway: the roles of Notch signaling in neural crest development.

21 January 2018

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Regeneration of sensory hair cells after acoustic trauma.

21 January 2018

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Hair cell fate decisions in cochlear development and regeneration

21 January 2018

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Bmp4 is essential for the formation of the vestibular apparatus that detects angular head movements

21 January 2018

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Delta-like 1 and lateral inhibition during hair cell formation in the chicken inner ear: evidence against cis-inhibition.

21 January 2018

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The many facets of Notch ligands

21 January 2018

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Sox2 signaling in prosensory domain specification and subsequent hair cell differentiation in the developing cochlea

21 January 2018

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Notch regulation of progenitor cell behavior in quiescent and regenerating auditory epithelium of mature birds.

21 January 2018

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Two contrasting roles for Notch activity in chick inner ear development: specification of prosensory patches and lateral inhibition of hair-cell differentiation.

21 January 2018

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Hey2 regulation by FGF provides a Notch-independent mechanism for maintaining pillar cell fate in the organ of Corti

21 January 2018

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Notch signaling in the development of the inner ear: lessons from Drosophila

21 January 2018

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DNER acts as a neuron-specific Notch ligand during Bergmann glial development

21 January 2018

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"Notch-Off": a perspective on the termination of Notch signalling

21 January 2018

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Delta-Notch--and then? Protein interactions and proposed modes of repression by Hes and Hey bHLH factors

21 January 2018

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Structural conservation of Notch receptors and ligands

21 January 2018

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Notch signaling: the core pathway and its posttranslational regulation

21 January 2018

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The role of bHLH genes in ear development and evolution: revisiting a 10-year-old hypothesis

21 January 2018

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Role of conserved intracellular motifs in Serrate signalling, cis-inhibition and endocytosis

21 January 2018

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Jagged1 is a competitive inhibitor of Notch signaling in the embryonic pancreas

21 January 2018

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Half a century of neural prepatterning: the story of a few bristles and many genes.

21 January 2018

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The cell adhesion molecule BEN defines a prosensory patch in the developing avian otocyst.

21 January 2018

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Shaping sound in space: the regulation of inner ear patterning

21 January 2018

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Hair cells without supporting cells: further studies in the ear of the zebrafish mind bomb mutant

21 January 2018

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Notch signaling specifies prosensory domains via lateral induction in the developing mammalian inner ear

21 January 2018

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Hesr1 and Hesr2 may act as early effectors of Notch signaling in the developing cochlea

21 January 2018

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Ganglion formation from the otic placode and the otic crest in the chick embryo: mitosis, migration, and the basal lamina

21 January 2018

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Expression of a Delta homologue in prospective neurons in the chick

21 January 2018

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Fringe differentially modulates Jagged1 and Delta1 signalling through Notch1 and Notch2.

21 January 2018

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Expression of LHX3 and SOX2 during mouse inner ear development

21 January 2018

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Dorsal-ventral signaling in limb development

21 January 2018

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HES and HERP families: multiple effectors of the Notch signaling pathway

21 January 2018

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HERP, a novel heterodimer partner of HES/E(spl) in Notch signaling

21 January 2018

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Mind bomb is a ubiquitin ligase that is essential for efficient activation of Notch signaling by Delta

21 January 2018

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Notch signaling augments the canonical Wnt pathway to specify the size of the otic placode

21 January 2018

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Notch signalling and the synchronization of the somite segmentation clock

21 January 2018

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Dynamic Notch signaling in neural progenitor cells and a revised view of lateral inhibition

21 January 2018

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Id gene regulation and function in the prosensory domains of the chicken inner ear: a link between Bmp signaling and Atoh1.

21 January 2018

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Hair cell development: commitment through differentiation

21 January 2018

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The Notch ligand Jagged1 is required for inner ear sensory development.

21 January 2018

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The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear.

21 January 2018

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Sox2 is required for sensory organ development in the mammalian inner ear

21 January 2018

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The Notch ligand JAG1 is required for sensory progenitor development in the mammalian inner ear

21 January 2018

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Mind bomb 1 is essential for generating functional Notch ligands to activate Notch

21 January 2018

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Direct response to Notch activation: signaling crosstalk and incoherent logic.

21 January 2018

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From shared lineage to distinct functions: the development of the inner ear and epibranchial placodes.

21 January 2018

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Notch signalling pathway mediates hair cell development in mammalian cochlea

21 January 2018

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Jagged 1 is necessary for normal mouse lens formation

21 January 2018

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An O-fucose site in the ligand binding domain inhibits Notch activation

21 January 2018

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Oscillating expression of c-Hey2 in the presomitic mesoderm suggests that the segmentation clock may use combinatorial signaling through multiple interacting bHLH factors

21 January 2018

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Distinct expression patterns of notch family receptors and ligands during development of the mammalian inner ear

21 January 2018

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Notch signalling and the control of cell fate choices in vertebrates.

21 January 2018

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Atoh1 expression and function during auditory hair cell regeneration in post-hatch chickens

21 January 2018

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Hey2 functions in parallel with Hes1 and Hes5 for mammalian auditory sensory organ development

21 January 2018

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Proneural enhancement by Notch overcomes Suppressor-of-Hairless repressor function in the developing Drosophila eye.

21 January 2018

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Expression patterns of Jagged, Delta1, Notch1, Notch2, and Notch3 genes identify ligand-receptor pairs that may function in neural development

21 January 2018

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Overactivation of Notch1 signaling induces ectopic hair cells in the mouse inner ear in an age-dependent manner

21 January 2018

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neurogenin1 is essential for the determination of neuronal precursors for proximal cranial sensory ganglia

21 January 2018

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CSL-independent Notch signalling: a checkpoint in cell fate decisions during development?

21 January 2018

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Synthetic signal propagation through direct cell-cell interaction.

21 January 2018

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Zebrafish atoh1 genes: classic proneural activity in the inner ear and regulation by Fgf and Notch

21 January 2018

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Mammalian Notch1 is modified with two unusual forms of O-linked glycosylation found on epidermal growth factor-like modules

21 January 2018

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Expression of Delta1 and Serrate1 (Jagged1) in the mouse inner ear

21 January 2018

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Atoh1, an essential transcription factor in neurogenesis and intestinal and inner ear development: function, regulation, and context dependency.

21 January 2018

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Notch signaling: from the outside in

21 January 2018

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The notch signalling regulator fringe acts in the Golgi apparatus and requires the glycosyltransferase signature motif DXD.

21 January 2018

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Notch-Hes1 pathway contributes to the cochlear prosensory formation potentially through the transcriptional down-regulation of p27Kip1.

21 January 2018

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A chick homologue of Serrate and its relationship with Notch and Delta homologues during central neurogenesis

21 January 2018

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Differential expression of Sox2 and Sox3 in neuronal and sensory progenitors of the developing inner ear of the chick.

21 January 2018

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Jagged 1 regulates the restriction of Sox2 expression in the developing chicken inner ear: a mechanism for sensory organ specification.

21 January 2018

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The prosensory function of Sox2 in the chicken inner ear relies on the direct regulation of Atoh1.

21 January 2018

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Patterning embryos with oscillations: structure, function and dynamics of the vertebrate segmentation clock

21 January 2018

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Hairy function as a DNA-binding helix-loop-helix repressor of Drosophila sensory organ formation.

21 January 2018

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Modulation of notch-ligand binding by protein O-fucosyltransferase 1 and fringe.

21 January 2018

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Target selectivity of vertebrate notch proteins. Collaboration between discrete domains and CSL-binding site architecture determines activation probability

21 January 2018

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Conservation of Pax 6 function and upstream activation by Notch signaling in eye development of frogs and flies

21 January 2018

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Notch signaling is required for the generation of hair cells and supporting cells in the mammalian inner ear.

21 January 2018

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Identification of differentially expressed genes in early inner ear development

21 January 2018

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Sox2 induces neuronal formation in the developing mammalian cochlea

21 January 2018

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Basic helix-loop-helix gene Hes6 delineates the sensory hair cell lineage in the inner ear.

21 January 2018

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Her9 represses neurogenic fate downstream of Tbx1 and retinoic acid signaling in the inner ear.

21 January 2018

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Cross-regulation of Ngn1 and Math1 coordinates the production of neurons and sensory hair cells during inner ear development.

21 January 2018

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Two Notch ligands, Dll1 and Jag1, are differently restricted in their range of action to control neurogenesis in the mammalian spinal cord.

21 January 2018

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Auditory system development: primary auditory neurons and their targets

21 January 2018

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Hair cell regeneration after acoustic trauma in adult Coturnix quail.

21 January 2018

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Clonal analysis of the relationships between mechanosensory cells and the neurons that innervate them in the chicken ear

21 January 2018

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Expression and functions of FGF ligands during early otic development.

21 January 2018

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Regulation of notch signaling activity

21 January 2018

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Expression of proneural and neurogenic genes in the embryonic mammalian vestibular system.

21 January 2018

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Manic fringe and lunatic fringe modify different sites of the Notch2 extracellular region, resulting in different signaling modulation

21 January 2018

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Cis-interactions between Notch and Delta generate mutually exclusive signalling states

21 January 2018

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Human homologs of a Drosophila Enhancer of split gene product define a novel family of nuclear proteins

21 January 2018

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Hair cell regeneration in the avian auditory epithelium.

21 January 2018

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Expression of Prox1 defines regions of the avian otocyst that give rise to sensory or neural cells

21 January 2018

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The preplacodal region: an ectodermal domain with multipotential progenitors that contribute to sense organs and cranial sensory ganglia.

21 January 2018

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Cooperative functions of Hes/Hey genes in auditory hair cell and supporting cell development

21 January 2018

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The mouse slalom mutant demonstrates a role for Jagged1 in neuroepithelial patterning in the organ of Corti

21 January 2018

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Negative regulation of proneural gene activity: hairy is a direct transcriptional repressor of achaete

21 January 2018

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Analysis of mouse kreisler mutants reveals new roles of hindbrain-derived signals in the establishment of the otic neurogenic domain.

21 January 2018

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Nucleotide sequence from the neurogenic locus notch implies a gene product that shares homology with proteins containing EGF-like repeats

21 January 2018

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Complementary and combinatorial patterns of Notch gene family expression during early mouse development.

21 January 2018

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Math1 regulates development of the sensory epithelium in the mammalian cochlea

21 January 2018

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Rbpj regulates development of prosensory cells in the mammalian inner ear.

21 January 2018

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Fringe glycosyltransferases differentially modulate Notch1 proteolysis induced by Delta1 and Jagged1

21 January 2018

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The Caenorhabditis elegans lin-12 gene encodes a transmembrane protein with overall similarity to Drosophila Notch

21 January 2018

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Zebrafish Mib and Mib2 are mutual E3 ubiquitin ligases with common and specific delta substrates

21 January 2018

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Overexpression of Math1 induces robust production of extra hair cells in postnatal rat inner ears

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/DGD.12016

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28 August 2017

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