(Q38080147)

28 August 2017

Methotrexate pharmacogenetics in rheumatoid arthritis: a status report (English)

1 reference

28 August 2017

1 reference

1 reference

Fardina Malik

1

1 reference

PubMed ID

23394392

28 August 2017

Prabha Ranganathan

series ordinal

2

1 reference

28 August 2017

1 February 2013

1 reference

28 August 2017

1 reference

28 August 2017

14

1 reference

28 August 2017

305-314

1 reference

28 August 2017

3

1 reference

The comparative efficacy and toxicity of second-line drugs in rheumatoid arthritis results of two metaanalyses

28 August 2017

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

Long-term prospective study of the use of methotrexate in the treatment of rheumatoid arthritis. Update after a mean of 90 months

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

Adalimumab, a fully human anti-tumor necrosis factor alpha monoclonal antibody, for the treatment of rheumatoid arthritis in patients taking concomitant methotrexate: the ARMADA trial

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

Long-term impact of early treatment on radiographic progression in rheumatoid arthritis: A meta-analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

Methotrexate pharmacogenetics: the first step toward individualized therapy in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

Methotrexate in rheumatoid arthritis: an update with focus on mechanisms involved in toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

Molecular action of methotrexate in inflammatory diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

Pharmacogenomic and metabolic biomarkers in the folate pathway and their association with methotrexate effects during dosage escalation in rheumatoid arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

677C>T and 1298A>C MTHFR polymorphisms affect methotrexate treatment outcome in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

Efficacy and toxicity of methotrexate in early rheumatoid arthritis are associated with single-nucleotide polymorphisms in genes coding for folate pathway enzymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

Polymorphisms in the methylenetetrahydrofolate reductase gene were associated with both the efficacy and the toxicity of methotrexate used for the treatment of rheumatoid arthritis, as evidenced by single locus and haplotype analyses

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

The C677T mutation in the methylenetetrahydrofolate reductase gene: a genetic risk factor for methotrexate-related elevation of liver enzymes in rheumatoid arthritis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

Risk genotypes in folate-dependent enzymes and their association with methotrexate-related side effects in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

A second common mutation in the methylenetetrahydrofolate reductase gene: an additional risk factor for neural-tube defects?

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

Genetic polymorphisms in metabolic and cellular transport pathway of methotrexate impact clinical outcome of methotrexate monotherapy in Japanese patients with rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

Racial or ethnic differences in allele frequencies of single-nucleotide polymorphisms in the methylenetetrahydrofolate reductase gene and their influence on response to methotrexate in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

Genetic determinants of methotrexate toxicity in rheumatoid arthritis patients: a study of polymorphisms affecting methotrexate transport and folate metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

Polymorphisms C677T and A1298C in the MTHFR gene in Mexican patients with rheumatoid arthritis treated with methotrexate: implication with elevation of transaminases.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

Contribution of common polymorphisms in reduced folate carrier and gamma-glutamylhydrolase to methotrexate polyglutamate levels in patients with rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

Genetic polymorphisms in folate pathway enzymes as a possible marker for predicting the outcome of methotrexate therapy in Japanese patients with rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

Genetic determinants of methotrexate treatment in rheumatoid arthritis patients: a study of polymorphisms in the adenosine pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

Metaanalysis of methylenetetrahydrofolate reductase (MTHFR) polymorphisms affecting methotrexate toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

Gene-gene interactions in folate and adenosine biosynthesis pathways affect methotrexate efficacy and tolerability in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

Candidate-gene approaches for studying complex genetic traits: practical considerations

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

A comprehensive review of genetic association studies

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

Pharmacogenomics: the inherited basis for interindividual differences in drug response

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

Investigation of candidate polymorphisms and disease activity in rheumatoid arthritis patients on methotrexate

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

Functional polymorphisms and methotrexate treatment outcome in recent-onset rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

667C>T and 1298A>C polymorphisms of MTHFR do not predict response to methotrexate in patients with gestational trophoblastic neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

Effect of the methylenetetrahydrofolate reductase C677T polymorphism on chemosensitivity of colon and breast cancer cells to 5-fluorouracil and methotrexate

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

C677T and A1298C MTHFR polymorphisms, a challenge for antifolate and fluoropyrimidine-based therapy personalisation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

An update on methotrexate pharmacogenetics in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

Are Thymidylate synthase and Methylene tetrahydrofolate reductase genes linked with methotrexate response (efficacy, toxicity) in Indian (Asian) rheumatoid arthritis patients?

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

Preliminary study to identify the predictive factors for the response to methotrexate therapy in patients with rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

Associations between methotrexate treatment and methylenetetrahydrofolate reductase gene polymorphisms with incident fractures in Japanese female rheumatoid arthritis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

Polymorphisms within the folate pathway predict folate concentrations but are not associated with disease activity in rheumatoid arthritis patients on methotrexate

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

Purine biosynthetic pathway genes and methotrexate response in rheumatoid arthritis patients among north Indians

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

Patterns of interaction between genetic and nongenetic attributes and methotrexate efficacy in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

A clinical pharmacogenetic model to predict the efficacy of methotrexate monotherapy in recent-onset rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

The C677T polymorphism in theMTHFRgene is associated with the toxicity of methotrexate in a Spanish rheumatoid arthritis population

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.12.214

21 January 2018

Identifiers

DOI

10.2217/PGS.12.214

1 reference

28 August 2017

1 reference

PubMed ID

23394392