(Q38081986)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23414473%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

title

MITF, the Janus transcription factor of melanoma (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23414473%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23414473%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Irwin Davidson

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23414473%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

author name string

Dana Koludrovic

series ordinal

1

1 reference

28 August 2017

Irwin Davidson

series ordinal

2

1 reference

28 August 2017

language of work or name

English

0 references

publication date

1 February 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23414473%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23414473%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

volume

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23414473%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23414473%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

page(s)

235-244

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23414473%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

How to make a melanoma: what do we know of the primary clonal events?

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Fifteen-year quest for microphthalmia-associated transcription factor target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

In vivo switching of human melanoma cells between proliferative and invasive states

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Systematic classification of melanoma cells by phenotype-specific gene expression mapping.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Transcriptional and signaling regulation in neural crest stem cell-derived melanocyte development: do all roads lead to Mitf?

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

MITF: master regulator of melanocyte development and melanoma oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

"Lineage addiction" in human cancer: lessons from integrated genomics

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Cancer stem cells versus phenotype-switching in melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Advances in melanoma senescence and potential clinical application.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Melanocytes and the microphthalmia transcription factor network

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Mutations at the mouse microphthalmia locus are associated with defects in a gene encoding a novel basic-helix-loop-helix-zipper protein

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Isoforms of mi transcription factor preferentially expressed in cultured mast cells of mice

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Mitf-D, a newly identified isoform, expressed in the retinal pigment epithelium and monocyte-lineage cells affected by Mitf mutations.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

The identification and functional characterization of a novel mast cell isoform of the microphthalmia-associated transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Microphthalmia gene product as a signal transducer in cAMP-induced differentiation of melanocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Mutations of the BRAF gene in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

V599EB-RAF is an oncogene in melanocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Mutant V599EB-Raf regulates growth and vascular development of malignant melanoma tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Targeting mutant (V600E) B-Raf in melanoma interrupts immunoediting of leukocyte functions and melanoma extravasation.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Targeting mitogen-activated protein kinase/extracellular signal-regulated kinase kinase in the mutant (V600E) B-Raf signaling cascade effectively inhibits melanoma lung metastases

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Oncogenic Braf induces melanocyte senescence and melanoma in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Simultaneous knockdown of BRAF and expression of INK4A in melanoma cells leads to potent growth inhibition and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Braf(V600E) cooperates with Pten loss to induce metastatic melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Elevated expression of MITF counteracts B-RAF-stimulated melanocyte and melanoma cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Oncogenic BRAF regulates melanoma proliferation through the lineage specific factor MITF.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

The Brn-2 transcription factor links activated BRAF to melanoma proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Intravital imaging reveals transient changes in pigment production and Brn2 expression during metastatic melanoma dissemination

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Inverse expression states of the BRN2 and MITF transcription factors in melanoma spheres and tumour xenografts regulate the NOTCH pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Genome-wide analysis of POU3F2/BRN2 promoter occupancy in human melanoma cells reveals Kitl as a novel regulated target gene

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Melanoma cell invasiveness is regulated by miR-211 suppression of the BRN2 transcription factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Phosphorylation of BRN2 modulates its interaction with the Pax3 promoter to control melanocyte migration and proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Beta-catenin: a key mediator of Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Brn-2 expression controls melanoma proliferation and is directly regulated by beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Microphthalmia-associated transcription factor interacts with LEF-1, a mediator of Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

The microphthalmia-associated transcription factor Mitf interacts with beta-catenin to determine target gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Beta-catenin induces immortalization of melanocytes by suppressing p16INK4a expression and cooperates with N-Ras in melanoma development

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Activation of beta-catenin by hypoxia in hepatocellular carcinoma contributes to enhanced metastatic potential and poor prognosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Activated Wnt/beta-catenin signaling in melanoma is associated with decreased proliferation in patient tumors and a murine melanoma model

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

In melanoma, beta-catenin is a suppressor of invasion.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

SOX10 Maintains Multipotency and Inhibits Neuronal Differentiation of Neural Crest Stem Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

The importance of having your SOX on: role of SOX10 in the development of neural crest-derived melanocytes and glia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Analysis of SOX10 function in neural crest-derived melanocyte development: SOX10-dependent transcriptional control of dopachrome tautomerase

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Interspecies difference in the regulation of melanocyte development by SOX10 and MITF.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Pax3 functions at a nodal point in melanocyte stem cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

splotch (Sp2H), a mutation affecting development of the mouse neural tube, shows a deletion within the paired homeodomain of Pax-3

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Endothelin signalling in the development of neural crest-derived melanocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Epistatic connections between microphthalmia-associated transcription factor and endothelin signaling in Waardenburg syndrome and other pigmentary disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Physiological factors that regulate skin pigmentation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Cloning of the human GLI2 Promoter: transcriptional activation by transforming growth factor-beta via SMAD3/beta-catenin cooperation

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

GLI2-mediated melanoma invasion and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

GLI2 and M-MITF transcription factors control exclusive gene expression programs and inversely regulate invasion in human melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Expression of microphthalmia-associated transcription factor (MITF), which is critical for melanoma progression, is inhibited by both transcription factor GLI2 and transforming growth factor-β.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

The microphthalmia-associated transcription factor requires SWI/SNF enzymes to activate melanocyte-specific genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Heterogeneous SWI/SNF chromatin remodeling complexes promote expression of microphthalmia-associated transcription factor target genes in melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

SWI/SNF chromatin remodeling complex is critical for the expression of microphthalmia-associated transcription factor in melanoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Melanocyte-specific expression of the human tyrosinase promoter: activation by the microphthalmia gene product and role of the initiator.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Mitf cooperates with Rb1 and activates p21Cip1 expression to regulate cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

MITF links differentiation with cell cycle arrest in melanocytes by transcriptional activation of INK4A

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Critical role of CDK2 for melanoma growth linked to its melanocyte-specific transcriptional regulation by MITF

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Hypoxia-inducible factor 1{alpha} is a new target of microphthalmia-associated transcription factor (MITF) in melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Bcl2 regulation by the melanocyte master regulator Mitf modulates lineage survival and melanoma cell viability

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

The gene encoding the T-box factor Tbx2 is a target for the microphthalmia-associated transcription factor in melanocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Mitf expression is sufficient to direct differentiation of medaka blastula derived stem cells to melanocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19(ARF)) and is amplified in a subset of human breast cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Tbx2 directly represses the expression of the p21(WAF1) cyclin-dependent kinase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Tbx2 is overexpressed and plays an important role in maintaining proliferation and suppression of senescence in melanomas

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Mitf regulation of Dia1 controls melanoma proliferation and invasiveness

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Senescent cells develop a PARP-1 and nuclear factor-{kappa}B-associated secretome (PNAS)

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Structure and function of mammalian DNA ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Emergence of a DNA-damage response network consisting of Fanconi anaemia and BRCA proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Mice without telomerase: what can they teach us about human cancer?

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Telomeres and telomerase in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Specific association of human telomerase activity with immortal cells and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

RaLP, a new member of the Src homology and collagen family, regulates cell migration and tumor growth of metastatic melanomas

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Sumoylation modulates transcriptional activity of MITF in a promoter-specific manner

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

A novel recurrent mutation in MITF predisposes to familial and sporadic melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

YY1 regulates melanocyte development and function by cooperating with MITF.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

Brn-2 Represses Microphthalmia-Associated Transcription Factor Expression and Marks a Distinct Subpopulation of Microphthalmia-Associated Transcription Factor-Negative Melanoma Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

MAP kinase links the transcription factor Microphthalmia to c-Kit signalling in melanocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FFON.12.177

21 January 2018

Identifiers

DOI

10.2217/FON.12.177

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23414473%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

1 reference