(Q38084202)

28 August 2017

Role of the Toll Like receptor (TLR) radical cycle in chronic inflammation: possible treatments targeting the TLR4 pathway (English)

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28 August 2017

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2

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28 August 2017

Kurt Lucas

1

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28 August 2017

26 February 2013

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28 August 2017

Molecular Neurobiology

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28 August 2017

48

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28 August 2017

1

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28 August 2017

190-204

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https://scigraph.springernature.com/pub.10.1007/s12035-013-8425-7

28 August 2017

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cites work

In vitro activation of murine peritoneal macrophages by ultraviolet B radiation: upregulation of CD18, production of NO, proinflammatory cytokines and a signal transduction pathway.

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12 December 2020

Novel interactions of a microbial superantigen with TLR2 and TLR4 differentially regulate IL-17 and Th17-associated cytokines.

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12 December 2020

Cinnamon extract protects against acute alcohol-induced liver steatosis in mice

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12 December 2020

Chronic fine particulate matter exposure induces systemic vascular dysfunction via NADPH oxidase and TLR4 pathways

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12 December 2020

Toll-like receptor (TLR2 and TLR4) polymorphisms and chronic obstructive pulmonary disease

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12 December 2020

The innate and adaptive immune response induced by alveolar macrophages exposed to ambient particulate matter

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12 December 2020

TBK1-targeted suppression of TRIF-dependent signaling pathway of Toll-like receptors by 6-shogaol, an active component of ginger

1 reference

12 December 2020

Hyaluronic acid is radioprotective in the intestine through a TLR4 and COX-2-mediated mechanism

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12 December 2020

Signaling pathway of inflammatory responses in the mouse liver caused by TiO2 nanoparticles.

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12 December 2020

Effect of baicalin on toll-like receptor 4-mediated ischemia/reperfusion inflammatory responses in alcoholic fatty liver condition.

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12 December 2020

Increased expression of toll-like receptor 4 and inflammatory cytokines, interleukin-6 in particular, in islets from a mouse model of obesity and type 2 diabetes

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12 December 2020

Identification of oxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injury

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12 December 2020

Extra domain A of fibronectin primes leukotriene biosynthesis and stimulates neutrophil migration through activation of Toll-like receptor 4

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12 December 2020

Suppression of MyD88- and TRIF-dependent signaling pathways of Toll-like receptor by (-)-epigallocatechin-3-gallate, a polyphenol component of green tea.

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12 December 2020

α-Lipoic acid prevents mild portal endotoxaemia-induced hepatic inflammation and β cell dysfunction.

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12 December 2020

Hyaluronan signaling during ozone-induced lung injury requires TLR4, MyD88, and TIRAP.

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12 December 2020

Ozone enhances pulmonary innate immune response to a Toll-like receptor-2 agonist

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12 December 2020

Gut, bugs, and brain: role of commensal bacteria in the control of central nervous system disease.

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12 December 2020

Substance P primes lipoteichoic acid- and Pam3CysSerLys4-mediated activation of human mast cells by up-regulating Toll-like receptor 2.

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12 December 2020

IL-1beta, TNFalpha and IL-6 induction in the rat brain after partial-body irradiation: role of vagal afferents.

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12 December 2020

Therapeutic inhibition of pro-inflammatory signaling and toxicity to staphylococcal enterotoxin B by a synthetic dimeric BB-loop mimetic of MyD88

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12 December 2020

Toll-like receptors modulate adult hippocampal neurogenesis

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12 December 2020

Therapeutic targeting of innate immunity with Toll-like receptor 4 (TLR4) antagonists

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12 December 2020

Aluminum as an adjuvant in Crohn's disease induction

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12 December 2020

Nitration enhances the allergenic potential of proteins.

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12 December 2020

Development of sensor cells using NF-κB pathway activation for detection of nanoparticle-induced inflammation

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12 December 2020

Intrinsic and extrinsic regulation of innate immune receptors

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12 December 2020

Intestinal permeability and function in patients infected with human immunodeficiency virus. A comparison with coeliac disease

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12 December 2020

Molecular mechanisms of hypertension--reactive oxygen species and antioxidants: a basic science update for the clinician

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12 December 2020

Prevalence of Small Intestinal Bacterial Overgrowth in Parkinson's Disease

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12 December 2020

Role of TLR2, TLR4, and MyD88 in murine ozone-induced airway hyperresponsiveness and neutrophilia

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12 December 2020

AS04, an aluminum salt- and TLR4 agonist-based adjuvant system, induces a transient localized innate immune response leading to enhanced adaptive immunity

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12 December 2020

Molecular hydrogen as an emerging therapeutic medical gas for neurodegenerative and other diseases

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12 December 2020

Recombinant factor C competes against LBP to bind lipopolysaccharide and neutralizes the endotoxicity

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12 December 2020

Protective effects of hydrogen-rich saline in a rat model of permanent focal cerebral ischemia via reducing oxidative stress and inflammatory cytokines.

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12 December 2020

Neural injury following stroke: are Toll-like receptors the link between the immune system and the CNS?

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12 December 2020

Ketamine inhibits lipopolysaccharide-induced astrocytes activation by suppressing TLR4/NF-ĸB pathway.

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12 December 2020

Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey

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12 December 2020

Crucial role for human Toll-like receptor 4 in the development of contact allergy to nickel

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12 December 2020

Diazinon immunotoxicity in mice: modulation of cytokines level and their gene expression.

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12 December 2020

Metal allergens nickel and cobalt facilitate TLR4 homodimerization independently of MD2.

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12 December 2020

Differential expression of Toll-like receptor 4 and human monocyte subsets in acute myocardial infarction

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12 December 2020

Propofol inhibits lipoteichoic acid-induced iNOS gene expression in macrophages possibly through downregulation of toll-like receptor 2-mediated activation of Raf-MEK1/2-ERK1/2-IKK-NFkappaB.

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12 December 2020

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

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12 December 2020

Ozone and pulmonary innate immunity

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12 December 2020

Open-label trial and randomized, double-blind, placebo-controlled, crossover trial of hydrogen-enriched water for mitochondrial and inflammatory myopathies

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12 December 2020

Differential monocyte responses to TLR ligands in children with autism spectrum disorders

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12 December 2020

Advances in carcinogenic metal toxicity and potential molecular markers

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12 December 2020

Pulmonary responses of mice, rats, and hamsters to subchronic inhalation of ultrafine titanium dioxide particles

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12 December 2020

Potential neurological lesion after nasal instillation of TiO(2) nanoparticles in the anatase and rutile crystal phases

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12 December 2020

A neuro-immune model of Myalgic Encephalomyelitis/Chronic fatigue syndrome

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12 December 2020

Effects of nano-scale TiO2, ZnO and their bulk counterparts on zebrafish: acute toxicity, oxidative stress and oxidative damage

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12 December 2020

C-reactive protein-induced in vitro endothelial cell activation is an artefact caused by azide and lipopolysaccharide

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12 December 2020

Effects of possible endocrine disruptors on MyD88-independent TLR4 signaling

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12 December 2020

Biophysical mechanisms of endotoxin neutralization by cationic amphiphilic peptides

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12 December 2020

Lipopolysaccharides impair insulin gene expression in isolated islets of Langerhans via Toll-Like Receptor-4 and NF-κB signalling

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12 December 2020

Anesthetic propofol reduces endotoxic inflammation by inhibiting reactive oxygen species-regulated Akt/IKKβ/NF-κB signaling

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12 December 2020

Baicalin inhibits TLR2/4 signaling pathway in rat brain following permanent cerebral ischemia

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12 December 2020

Hydroxyl radicals (*OH) are associated with titanium dioxide (TiO(2)) nanoparticle-induced cytotoxicity and oxidative DNA damage in fish cells

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12 December 2020

Neurotoxic effects of lipopolysaccharide on nigral dopaminergic neurons are mediated by microglial activation, interleukin-1beta, and expression of caspase-11 in mice

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12 December 2020

Stress mediators regulate brain prostaglandin synthesis and peroxisome proliferator-activated receptor-gamma activation after stress in rats

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12 December 2020

α-lipoic acid prevents non-alcoholic fatty liver disease in OLETF rats.

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12 December 2020

Increased serum IgA and IgM against LPS of enterobacteria in chronic fatigue syndrome (CFS): indication for the involvement of gram-negative enterobacteria in the etiology of CFS and for the presence of an increased gut-intestinal permeability.

1 reference

12 December 2020

Thinner inhalation effects on oxidative stress and DNA repair in a rat model of abuse

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12 December 2020

TLR4 is necessary for hyaluronan-mediated airway hyperresponsiveness after ozone inhalation

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12 December 2020

Alzheimer's disease and peripheral infections: the possible contribution from periodontal infections, model and hypothesis

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12 December 2020

Pathways of cholesterol oxidation via non-enzymatic mechanisms

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12 December 2020

The gut-brain barrier in major depression: intestinal mucosal dysfunction with an increased translocation of LPS from gram negative enterobacteria (leaky gut) plays a role in the inflammatory pathophysiology of depression

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12 December 2020

Evaluation of systemic markers of inflammation in atomic-bomb survivors with special reference to radiation and age effects

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12 December 2020

A resveratrol and polyphenol preparation suppresses oxidative and inflammatory stress response to a high-fat, high-carbohydrate meal

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12 December 2020

Mucin secretion induced by titanium dioxide nanoparticles

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12 December 2020

Ionizing radiation stimulates secretion of pro-inflammatory cytokines: dose-response relationship, mechanisms and implications

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12 December 2020

Altered intestinal function in patients with chronic heart failure

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12 December 2020

Neurotoxins: free radical mechanisms and melatonin protection

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12 December 2020

Impact of emerging pollutants on pulmonary inflammation in asthmatic rats: ethanol vapors and agglomerated TiO2 nanoparticles.

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12 December 2020

Current concepts of the pathogenesis of inflammatory bowel disease

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12 December 2020

The Emerging Role of TLR and Innate Immunity in Cardiovascular Disease

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12 December 2020

Pathophysiology of psoriasis: coping endotoxins with bile acid therapy

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12 December 2020

The emerging role of the gut in chronic heart failure

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12 December 2020

Neuroimaging in drug and substance abuse part II: opioids and solvents

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12 December 2020

Toll-like receptor 4 is involved in subacute stress-induced neuroinflammation and in the worsening of experimental stroke

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12 December 2020

Newspapers and newspaper ink contain agonists for the ah receptor

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12 December 2020

Nickel allergy-promoting effects of microbial or inflammatory substances at the sensitization step in mice

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12 December 2020

Characteristic cytokine generation patterns in cancer cells and infiltrating lymphocytes in oral squamous cell carcinomas and the influence of chemoradiation combined with immunotherapy on these patterns

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12 December 2020

TLR4 antagonist reduces early-stage atherosclerosis in diabetic apolipoprotein E-deficient mice.

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12 December 2020

Reactive oxygen species and the pathogenesis of radiocontrast-induced nephropathy

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12 December 2020

Silver nanoparticles induce apoptosis through the toll-like receptor 2 pathway

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12 December 2020

Inflammasome formation and IL-1β release by human blood monocytes in response to silver nanoparticles.

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12 December 2020

Glycyrrhizin and isoliquiritigenin suppress the LPS sensor toll-like receptor 4/MD-2 complex signaling in a different manner

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12 December 2020

Salvianolic acid B inhibits hydrogen peroxide-induced endothelial cell apoptosis through regulating PI3K/Akt signaling

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12 December 2020

Enhanced peripheral toll-like receptor responses in psychosis: further evidence of a pro-inflammatory phenotype.

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12 December 2020

Role of reactive oxygen metabolites in organophosphate-bidrin-induced renal tubular cytotoxicity.

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12 December 2020

Ozone-induced lung injury and sterile inflammation. Role of toll-like receptor 4.

1 reference

12 December 2020

Baicalin suppresses expression of TLR2/4 and NF-κB in chlamydia trachomatis-infected mice

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12 December 2020

The importance of the gastrointestinal system in the pathogenesis of heart failure

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12 December 2020

Lipoic acid attenuates innate immune infiltration and activation in the visceral adipose tissue of obese insulin resistant mice

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12 December 2020

Toll-like receptor 2 and 4 genes influence susceptibility to adverse effects of traffic-related air pollution on childhood asthma

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12 December 2020

Gold nanoparticle-initiated free radical oxidations and halogen abstractions

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12 December 2020

Role of bacterial endotoxin in chronic heart failure: the gut of the matter.

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12 December 2020

Influence of fasting on intestinal permeability and disease activity in patients with rheumatoid arthritis.

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12 December 2020

Lipopolysaccharide (LPS) induced activation of the immune system in control rats and rats chronically exposed to a low level of the organothiophosphate insecticide, acephate

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12 December 2020

Potential mechanism for pentachlorophenol-induced carcinogenicity: a novel mechanism for metal-independent production of hydroxyl radicals

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12 December 2020

The role of long-lived reactive oxygen intermediates in the reaction of ozone with aerosol particles

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12 December 2020

Aluminum hydroxide adjuvants activate caspase-1 and induce IL-1beta and IL-18 release

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12 December 2020

Repeated social defeat increases the bactericidal activity of splenic macrophages through a Toll-like receptor-dependent pathway

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12 December 2020

Spinal TLR4 mediates the transition to a persistent mechanical hypersensitivity after the resolution of inflammation in serum-transferred arthritis

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12 December 2020

Molecular hydrogen ameliorates lipopolysaccharide-induced acute lung injury in mice through reducing inflammation and apoptosis

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12 December 2020

Neurotoxicological effects and the impairment of spatial recognition memory in mice caused by exposure to TiO2 nanoparticles

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12 December 2020

Effects of intrathecal epigallocatechin gallate, an inhibitor of Toll-like receptor 4, on chronic neuropathic pain in rats

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12 December 2020

Differential cardioprotective effects of salvianolic acid and tanshinone on acute myocardial infarction are mediated by unique signaling pathways

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12 December 2020

Enhanced autoimmunity, arthritis, and encephalomyelitis in mice with a reduced oxidative burst due to a mutation in the Ncf1 gene

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12 December 2020

The role of free radicals in the toxic and inflammatory effects of four different ultrafine particle types

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12 December 2020

Increased toll-like receptor activity in patients with metabolic syndrome

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12 December 2020

Toll-like receptor priming sensitizes macrophages to proinflammatory cytokine gene induction by deoxynivalenol and other toxicants

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12 December 2020

In depression, bacterial translocation may drive inflammatory responses, oxidative and nitrosative stress (O&NS), and autoimmune responses directed against O&NS-damaged neoepitopes

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12 December 2020

Determination of cell surface expression of Toll-like receptor 4 by cellular enzyme-linked immunosorbent assay and radiolabeling.

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12 December 2020

Silver nanoparticles modify VEGF signaling pathway and mucus hypersecretion in allergic airway inflammation

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12 December 2020

Oxidized phospholipid-induced inflammation is mediated by Toll-like receptor 2.

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12 December 2020

Aryl hydrocarbon receptor negatively regulates LPS-induced IL-6 production through suppression of histamine production in macrophages

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12 December 2020

A cyanobacterial LPS antagonist prevents endotoxin shock and blocks sustained TLR4 stimulation required for cytokine expression

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12 December 2020

Functional polymorphisms of Toll-like receptors 2 and 4 alter the risk for colorectal carcinoma in Europeans

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12 December 2020

Phase 2 trial of eritoran tetrasodium (E5564), a toll-like receptor 4 antagonist, in patients with severe sepsis

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12 December 2020

Titanium dioxide (P25) produces reactive oxygen species in immortalized brain microglia (BV2): implications for nanoparticle neurotoxicity.

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12 December 2020

Insight into the mechanisms regulating immune homeostasis in health and disease.

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12 December 2020

Top-down and bottom-up mechanisms in mind-body medicine: development of an integrative framework for psychophysiological research

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12 December 2020

N-acetylcysteine for major depressive episodes in bipolar disorder

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12 December 2020

Inhibition of homodimerization of Toll-like receptor 4 by curcumin

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12 December 2020

N-acetyl cysteine for depressive symptoms in bipolar disorder--a double-blind randomized placebo-controlled trial

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12 December 2020

The Role of TLR2 in Infection and Immunity

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12 December 2020

Role of hippocampal TLR4 in neurotoxicity in mice following toluene exposure.

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12 December 2020

Prevention and mitigation of acute radiation syndrome in mice by synthetic lipopeptide agonists of Toll-like receptor 2 (TLR2)

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12 December 2020

N-acetylcysteine reduces inflammation in the small intestine by regulating redox, EGF and TLR4 signaling.

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12 December 2020

N-acetylcysteine possesses antidepressant-like activity through reduction of oxidative stress: behavioral and biochemical analyses in rats.

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12 December 2020

Psychosocial interventions for reducing fatigue during cancer treatment in adults

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12 December 2020

10.1007/S12035-013-8425-7

Identifiers

DOI

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PubMed ID

23436141

Dimensions Publication ID

28 August 2017

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1 reference

PubMed ID

23436141