(Q38086773)

28 August 2017

DNA methylation dynamics in health and disease (English)

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28 August 2017

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Yehudit Bergman

1

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PubMed ID

23463312

28 August 2017

Howard Cedar

series ordinal

2

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28 August 2017

1 March 2013

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Nature Structural & Molecular Biology

28 August 2017

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28 August 2017

20

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28 August 2017

3

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28 August 2017

274-281

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https://scigraph.springernature.com/pub.10.1038/nsmb.2518

28 August 2017

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cites work

Developmental pattern of gene-specific DNA methylation in the mouse embryo and germ line

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A unique regulatory phase of DNA methylation in the early mammalian embryo

21 January 2018

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Active demethylation of the paternal genome in the mouse zygote

21 January 2018

1 reference

Replication-dependent loss of 5-hydroxymethylcytosine in mouse preimplantation embryos

21 January 2018

1 reference

Linking DNA methylation and histone modification: patterns and paradigms

21 January 2018

1 reference

Dnmt3L and the establishment of maternal genomic imprints.

21 January 2018

1 reference

A maternal-zygotic effect gene, Zfp57, maintains both maternal and paternal imprints

21 January 2018

1 reference

Hypomethylation of multiple imprinted loci in individuals with transient neonatal diabetes is associated with mutations in ZFP57

21 January 2018

1 reference

5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming

21 January 2018

1 reference

PGC7/Stella protects against DNA demethylation in early embryogenesis

21 January 2018

1 reference

Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes

21 January 2018

1 reference

Epigenetic restriction of embryonic cell lineage fate by methylation of Elf5.

21 January 2018

1 reference

Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells

21 January 2018

1 reference

Widespread and tissue specific age-related DNA methylation changes in mice.

21 January 2018

1 reference

Maternal ethanol consumption alters the epigenotype and the phenotype of offspring in a mouse model

21 January 2018

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Transgenerational epigenetic inheritance: more questions than answers.

21 January 2018

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DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

21 January 2018

1 reference

Sp1 elements protect a CpG island from de novo methylation

21 January 2018

1 reference

Developmental programming of CpG island methylation profiles in the human genome

21 January 2018

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Dynamic changes in the human methylome during differentiation

21 January 2018

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DNA methylation screening identifies driver epigenetic events of cancer cell survival

21 January 2018

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Programming of DNA methylation patterns

21 January 2018

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Identification of genetic elements that autonomously determine DNA methylation states.

21 January 2018

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Sp1 sites in the mouse aprt gene promoter are required to prevent methylation of the CpG island

21 January 2018

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DNA methylation represses transcription in vivo.

21 January 2018

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Fine tuning of globin gene expression by DNA methylation

21 January 2018

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Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome

21 January 2018

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DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA

21 January 2018

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Structural basis for recognition of H3K4 methylation status by the DNA methyltransferase 3A ATRX-DNMT3-DNMT3L domain

21 January 2018

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Cfp1 integrates both CpG content and gene activity for accurate H3K4me3 deposition in embryonic stem cells

21 January 2018

1 reference

Methylation of foreign DNA sequences in eukaryotic cells

21 January 2018

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Somatic mutations in the neurofibromatosis 1 gene in human tumors

21 January 2018

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A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei

21 January 2018

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UHRF1 plays a role in maintaining DNA methylation in mammalian cells

21 January 2018

1 reference

The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA

21 January 2018

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Recruitment of Dnmt1 roles of the SRA protein Np95 (Uhrf1) and other factors

21 January 2018

1 reference

The interaction of the SRA domain of ICBP90 with a novel domain of DNMT1 is involved in the regulation of VEGF gene expression

21 January 2018

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A high-resolution map of transcription in the yeast genome

21 January 2018

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TrxG and PcG proteins but not methylated histones remain associated with DNA through replication

21 January 2018

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Extinction of Oct-3/4 gene expression in embryonal carcinoma x fibroblast somatic cell hybrids is accompanied by changes in the methylation status, chromatin structure, and transcriptional activity of the Oct-3/4 upstream region

21 January 2018

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A unique developmental pattern of Oct-3/4 DNA methylation is controlled by a cis-demodification element

21 January 2018

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G9a-mediated irreversible epigenetic inactivation of Oct-3/4 during early embryogenesis.

21 January 2018

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De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes

21 January 2018

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Histone acetylation and X inactivation

21 January 2018

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Role of histone H3 lysine 27 methylation in X inactivation

21 January 2018

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Establishment of histone h3 methylation on the inactive X chromosome requires transient recruitment of Eed-Enx1 polycomb group complexes

21 January 2018

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Smchd1-dependent and -independent pathways determine developmental dynamics of CpG island methylation on the inactive X chromosome.

21 January 2018

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DNA methylation stabilizes X chromosome inactivation in eutherians but not in marsupials: evidence for multistep maintenance of mammalian X dosage compensation

21 January 2018

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Cooperativity between DNA methyltransferases in the maintenance methylation of repetitive elements

21 January 2018

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Rethinking how DNA methylation patterns are maintained

21 January 2018

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A novel CpG island set identifies tissue-specific methylation at developmental gene loci

21 January 2018

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The Polycomb group protein EZH2 directly controls DNA methylation

21 January 2018

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Oxidative damage targets complexes containing DNA methyltransferases, SIRT1, and polycomb members to promoter CpG Islands

21 January 2018

1 reference

TGF-β-dependent active demethylation and expression of the p15ink4b tumor suppressor are impaired by the ZNF217/CoREST complex

21 January 2018

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B cell-specific demethylation: a novel role for the intronic kappa chain enhancer sequence

21 January 2018

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Multiple elements influence transcriptional regulation from the human testis-specific PGK2 promoter in transgenic mice.

21 January 2018

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A role for nuclear NF-kappaB in B-cell-specific demethylation of the Igkappa locus

21 January 2018

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Epigenetic ontogeny of the Igk locus during B cell development

21 January 2018

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An integrated encyclopedia of DNA elements in the human genome

21 January 2018

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Delta-crystallin genes become hypomethylated in postmitotic lens cells during chicken development

21 January 2018

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A mammalian protein with specific demethylase activity for mCpG DNA.

21 January 2018

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MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex

21 January 2018

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Nuclear extracts of chicken embryos promote an active demethylation of DNA by excision repair of 5-methyldeoxycytidine

21 January 2018

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DNA demethylation in vitro: involvement of RNA.

21 January 2018

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Replacement of 5-methylcytosine by cytosine: a possible mechanism for transient DNA demethylation during differentiation

21 January 2018

1 reference

Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells.

21 January 2018

1 reference

Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine

21 January 2018

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The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes

21 January 2018

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Mechanisms and functions of Tet protein-mediated 5-methylcytosine oxidation

21 January 2018

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Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA

21 January 2018

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Endogenous cytosine damage products alter the site selectivity of human DNA maintenance methyltransferase DNMT1.

21 January 2018

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Recognition and potential mechanisms for replication and erasure of cytosine hydroxymethylation

21 January 2018

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Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency.

21 January 2018

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Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain

21 January 2018

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Cytidine deaminases: AIDing DNA demethylation?

21 January 2018

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An unexpectedly high excision capacity for mispaired 5-hydroxymethyluracil in human cell extracts

21 January 2018

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AID/APOBEC deaminases disfavor modified cytosines implicated in DNA demethylation.

21 January 2018

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Developmental regulation of immune system gene rearrangement

21 January 2018

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An estrogen-dependent demethylation at the 5′ end of the chicken vitellogenin gene is independent of DNA synthesis

21 January 2018

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Sequential changes in DNA methylation patterns of the rat phosphoenolpyruvate carboxykinase gene during development

21 January 2018

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Methylation changes in the apolipoprotein AI gene during embryonic development of the mouse

21 January 2018

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DNA methylation: a molecular lock

21 January 2018

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A histone acetyltransferase regulates active DNA demethylation in Arabidopsis

21 January 2018

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The fundamental role of epigenetic events in cancer

21 January 2018

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The epigenomics of cancer

21 January 2018

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Altered methylation patterns in cancer cell genomes: cause or consequence?

21 January 2018

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Frequent switching of Polycomb repressive marks and DNA hypermethylation in the PC3 prostate cancer cell line

21 January 2018

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Evidence for an instructive mechanism of de novo methylation in cancer cells.

21 January 2018

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Integrated genomic and epigenomic analyses pinpoint biallelic gene inactivation in tumors

21 January 2018

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A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing

21 January 2018

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Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer

21 January 2018

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Epigenetic stem cell signature in cancer

21 January 2018

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Human aging-associated DNA hypermethylation occurs preferentially at bivalent chromatin domains

21 January 2018

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Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer.

21 January 2018

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Characteristic methylation profile in CpG island methylator phenotype-negative distal colorectal cancers.

21 January 2018

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Patterns of DNA methylation in individual colonic crypts reveal aging and cancer-related field defects in the morphologically normal mucosa.

21 January 2018

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IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics

21 January 2018

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Cancer genetics and epigenetics: two sides of the same coin?

21 January 2018

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Hypomethylation distinguishes genes of some human cancers from their normal counterparts

21 January 2018

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Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina-associated domains

21 January 2018

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Global DNA hypomethylation coupled to repressive chromatin domain formation and gene silencing in breast cancer

21 January 2018

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Suppression of intestinal neoplasia by DNA hypomethylation.

21 January 2018

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Inhibition of DNA methyltransferase activity prevents tumorigenesis in a mouse model of prostate cancer

21 January 2018

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Transient low doses of DNA-demethylating agents exert durable antitumor effects on hematological and epithelial tumor cells

21 January 2018

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DNA methyltransferase inhibitor, zebularine, delays tumor growth and induces apoptosis in a genetically engineered mouse model of breast cancer

21 January 2018

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Induction of Tumors in Mice by Genomic Hypomethylation

21 January 2018

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Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis

21 January 2018

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CpG islands influence chromatin structure via the CpG-binding protein Cfp1.

21 January 2018

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Demethylation of the zygotic paternal genome

21 January 2018

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Substrate and sequence specificity of a eukaryotic DNA methylase

21 January 2018

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21 January 2018

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Differences in DNA methylation during oogenesis and spermatogenesis and their persistence during early embryogenesis in the mouse

21 January 2018

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The ontogeny of allele-specific methylation associated with imprinted genes in the mouse.

31 March 2020

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PGC7 binds histone H3K9me2 to protect against conversion of 5mC to 5hmC in early embryos

31 March 2020

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Genome-scale DNA methylation maps of pluripotent and differentiated cells

31 March 2020

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Muscle-specific activation of a methylated chimeric actin gene

31 March 2020

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Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

31 March 2020

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Methylation of the Hprt gene on the inactive X occurs after chromosome inactivation

31 March 2020

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Role of DNA Methylation in Stable Gene Repression

31 March 2020

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Dynamics of demethylation and activation of the alpha-actin gene in myoblasts

31 March 2020

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DNA-binding factors shape the mouse methylome at distal regulatory regions

31 March 2020

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Hypomethylation is necessary but not sufficient for V(D)J recombination within a transgenic substrate

31 March 2020

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Developmental changes in the methylation of the rat albumin and alpha-fetoprotein genes.

31 March 2020

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DNA methylation and the regulation of globin gene expression

31 March 2020

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Worms gang up on bacteria

31 March 2020

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12 December 2020

Inhibition of DNA methylation and histone deacetylation prevents murine lung cancer

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12 December 2020

Inhibition of DNA methylation by 5-aza-2'-deoxycytidine suppresses the growth of human tumor cell lines

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12 December 2020

Mitochondria and the death of oocytes

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12 December 2020

Temporal and regional changes in DNA methylation in the embryonic, extraembryonic and germ cell lineages during mouse embryo development

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12 December 2020

Identifiers

DOI

10.1038/NSMB.2518

1 reference

28 August 2017

1 reference

PubMed ID

23463312