(Q38089151)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23488998%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

title

How to design multi-target drugs (English)

1 reference

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25 February 2020

4

1 reference

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25 February 2020

author name string

Tamás Korcsmáros

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23488998%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

Máté S Szalay

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23488998%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

Csaba Böde

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23488998%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

Péter Csermely

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23488998%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

language of work or name

English

0 references

publication date

1 June 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23488998%20AND%20SRC:MED&resulttype=core&format=json

Expert Opinion on Drug Discovery

25 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23488998%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

volume

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23488998%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

page(s)

799-808

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23488998%20AND%20SRC:MED&resulttype=core&format=json

25 February 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23488998%20AND%20SRC:MED&resulttype=core&format=json

Rediscovering the sweet spot in drug discovery.

25 February 2020

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Systematic discovery of multicomponent therapeutics

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Multicomponent therapeutics for networked systems

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Deconvolution of a complex target using DNA aptamers.

21 January 2018

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Strategies for efficient lead structure discovery from natural products.

21 January 2018

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Pseudomonas aeruginosa type III-secreted toxin ExoT inhibits host-cell division by targeting cytokinesis at multiple steps

21 January 2018

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Metabolic network analysis of the causes and evolution of enzyme dispensability in yeast.

21 January 2018

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Chance and necessity in the evolution of minimal metabolic networks

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A robustness-based approach to systems-oriented drug design.

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From large networks to small molecules

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Drug discovery: playing dirty

21 January 2018

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Rational drug discovery: what can we learn from regulatory networks?

21 January 2018

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From magic bullets to designed multiple ligands

21 January 2018

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Low affinity channel blocking (uncompetitive) NMDA receptor antagonists as therapeutic agents--toward an understanding of their favorable tolerability

21 January 2018

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Malignant glioma drug discovery - targeting protein kinases

21 January 2018

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Heat shock proteins as emerging therapeutic targets

21 January 2018

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Inhibition of Hsp90: a new strategy for inhibiting protein kinases

21 January 2018

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Multi-functional drugs for various CNS targets in the treatment of neurodegenerative disorders

21 January 2018

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Recombinant polyclonal antibodies for cancer therapy

21 January 2018

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Design and application of diabodies, triabodies and tetrabodies for cancer targeting

21 January 2018

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Network biology: understanding the cell's functional organization

21 January 2018

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Emergence of Scaling in Random Networks

21 January 2018

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Uncovering the overlapping community structure of complex networks in nature and society

21 January 2018

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Collective dynamics of 'small-world' networks

21 January 2018

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The metabolic world of Escherichia coli is not small

21 January 2018

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Some protein interaction data do not exhibit power law statistics

21 January 2018

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Protein-interaction mapping in search of effective drug targets

21 January 2018

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Critical nodes in signalling pathways: insights into insulin action

21 January 2018

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Methods to reveal domain networks

21 January 2018

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The SUPERFAMILY database in 2007: families and functions

21 January 2018

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Systems biology, metabolic modelling and metabolomics in drug discovery and development

21 January 2018

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Cytoskeletal integrity as a drug target

21 January 2018

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Predicting protein-protein interactions based only on sequences information

21 January 2018

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Relating three-dimensional structures to protein networks provides evolutionary insights

21 January 2018

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Turning down, but not off.

21 January 2018

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Rational drug design via intrinsically disordered protein.

21 January 2018

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Strong links are important, but weak links stabilize them

21 January 2018

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Low micronutrient intake may accelerate the degenerative diseases of aging through allocation of scarce micronutrients by triage

21 January 2018

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Mathematical modeling suggests cooperative interactions between a disordered polyvalent ligand and a single receptor site

21 January 2018

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Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication

21 January 2018

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21 January 2018

Network theory of aging

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Error and attack tolerance of complex networks

21 January 2018

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Resilience of the Internet to Random Breakdowns

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Protein-protein interactions as a target for drugs in proteomics

21 January 2018

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Neural networks applied to quantitative structure-activity relationship analysis

21 January 2018

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The efficiency of multi-target drugs: the network approach might help drug design

21 January 2018

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Cancer: a Systems Biology disease

21 January 2018

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A network dysfunction perspective on neurodegenerative diseases

21 January 2018

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Aging cellular networks: chaperones as major participants

21 January 2018

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Inferring genetic networks and identifying compound mode of action via expression profiling

21 January 2018

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Chemogenomic profiling: identifying the functional interactions of small molecules in yeast

21 January 2018

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Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes

21 January 2018

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The fall and rise of in vivo pharmacology.

21 January 2018

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Fractal dynamics in physiology: Alterations with disease and aging

21 January 2018

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Detection of compound mode of action by computational integration of whole-genome measurements and genetic perturbations

21 January 2018

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Untangling the wires: a strategy to trace functional interactions in signaling and gene networks

21 January 2018

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Reverse engineering gene networks: Integrating genetic perturbations with dynamical modeling

21 January 2018

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A Set of Measures of Centrality Based on Betweenness

21 January 2018

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Complex networks: Structure and dynamics

21 January 2018

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Exploring the Mode-of-Action of Bioactive Compounds by Chemical-Genetic Profiling in Yeast

21 January 2018

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