(Q38089698)

28 August 2017

Vinculin, cell mechanics and tumour cell invasion (English)

1 reference

28 August 2017

Ben Fabry

4

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author name string

Wolfgang H Goldmann

series ordinal

1

1 reference

PubMed ID

23494917

28 August 2017

Vera Auernheimer

series ordinal

2

1 reference

PubMed ID

23494917

28 August 2017

Ingo Thievessen

series ordinal

3

1 reference

28 August 2017

13 March 2013

1 reference

Cell Biology International

28 August 2017

1 reference

28 August 2017

37

1 reference

28 August 2017

5

1 reference

28 August 2017

397-405

1 reference

Structural basis for vinculin activation at sites of cell adhesion.

28 August 2017

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Force and focal adhesion assembly: a close relationship studied using elastic micropatterned substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Adhesion-mediated mechanosensitivity: a time to experiment, and a time to theorize.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

The vinculin binding sites of talin and alpha-actinin are sufficient to activate vinculin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Crystal structure of human vinculin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Crk-associated substrate tyrosine phosphorylation sites are critical for invasion and metastasis of SRC-transformed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

The role of the tissue microenvironment in the regulation of cancer cell motility and invasion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Occupy tissue: the movement in cancer metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

An interaction between vinculin and talin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Vinculin, an adapter protein in control of cell adhesion signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Vinculin regulates the recruitment and release of core focal adhesion proteins in a force-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Vinculin acts as a sensor in lipid regulation of adhesion-site turnover.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Roles of Rho-associated kinase and myosin light chain kinase in morphological and migratory defects of focal adhesion kinase-null cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Coincidence of actin filaments and talin is required to activate vinculin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Extracellular matrix rigidity causes strengthening of integrin-cytoskeleton linkages

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Two distinct head-tail interfaces cooperate to suppress activation of vinculin by talin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Targeted disruption of vinculin genes in F9 and embryonic stem cells changes cell morphology, adhesion, and locomotion

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

An interaction between zyxin and alpha-actinin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Focal adhesions - the cytoskeletal connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Cytoskeletal proteins talin and vinculin in integrin-mediated adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Recruitment of the Arp2/3 complex to vinculin: coupling membrane protrusion to matrix adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Localized mechanical stress induces time-dependent actin cytoskeletal remodeling and stiffening in cultured airway smooth muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Comparing mechano-transduction in fibroblasts deficient of focal adhesion proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Anchorage of vinculin to lipid membranes influences cell mechanical properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Identification of actin-, alpha-actinin-, and vinculin-containing plaques at the lateral membrane of epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Vinculin promotes cell spreading by mechanically coupling integrins to the cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

The biology of cell locomotion within three-dimensional extracellular matrix

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Collective cell migration in morphogenesis, regeneration and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Tumour-cell invasion and migration: diversity and escape mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Plasticity of cell migration: a multiscale tuning model

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

The relationship between force and focal complex development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

The cytoplasmic domain of adherens-type junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Vinculin, an intracellular protein localized at specialized sites where microfilament bundles terminate at cell membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Talin1 is critical for force-dependent reinforcement of initial integrin-cytoskeleton bonds but not tyrosine kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Mechanical aspects of cell shape regulation and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Mechanotransduction in cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Vinculin, talin and focal adhesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Differences in elasticity of vinculin-deficient F9 cells measured by magnetometry and atomic force microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Motility of vinculin-deficient F9 embryonic carcinoma cells analyzed by video, laser confocal, and reflection interference contrast microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Phosphorylation primes vinculin for activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Dynamic molecular processes mediate cellular mechanotransduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Differential transmission of actin motion within focal adhesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Activation of vinculin induced by cholinergic stimulation regulates contraction of tracheal smooth muscle tissue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Vinculin controls focal adhesion formation by direct interactions with talin and actin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Vinculin associates with endothelial VE-cadherin junctions to control force-dependent remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Integrins: bidirectional, allosteric signaling machines

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

How force might activate talin's vinculin binding sites: SMD reveals a structural mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Phospholipids stimulate phosphorylation of vinculin by the tyrosine-specific protein kinase of Rous sarcoma virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Two-piconewton slip bond between fibronectin and the cytoskeleton depends on talin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

F-actin binding site masked by the intramolecular association of vinculin head and tail domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

A conserved motif in the tail domain of vinculin mediates association with and insertion into acidic phospholipid bilayers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Nanoscale architecture of integrin-based cell adhesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

3D Traction forces in cancer cell invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Cellular traction stresses increase with increasing metastatic potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Tyrosine phosphorylation of vinculin at position 1065 modifies focal adhesion dynamics and cell tractions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Vinculin potentiates E-cadherin mechanosensing and is recruited to actin-anchored sites within adherens junctions in a myosin II-dependent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Mechanotransduction at cadherin-mediated adhesions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Snail1 controls epithelial-mesenchymal lineage commitment in focal adhesion kinase-null embryonic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Expression of the adherens junction protein vinculin in human basal and squamous cell tumors: relationship to invasiveness and metastatic potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Expression and function of vinculin in neuroendocrine tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Interactions of tensin with actin and identification of its three distinct actin-binding domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Mechanotransduction in vivo by repeated talin stretch-relaxation events depends upon vinculin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Mechano-coupling and regulation of contractility by the vinculin tail domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Vinculin facilitates cell invasion into three-dimensional collagen matrices

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Contractile forces in tumor cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

The Helicobacter pylori CagA protein disrupts matrix adhesion of gastric epithelial cells by dephosphorylation of vinculin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Becoming stable and strong: the interplay between vinculin exchange dynamics and adhesion strength during adhesion site maturation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Position-dependent linkages of fibronectin- integrin-cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Tensional homeostasis and the malignant phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

New insights into vinculin function and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Nonpolarized signaling reveals two distinct modes of 3D cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Overexpression of vinculin suppresses cell motility in BALB/c 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Suppression of vinculin expression by antisense transfection confers changes in cell morphology, motility, and anchorage-dependent growth of 3T3 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Suppression of tumorigenicity in transformed cells after transfection with vinculin cDNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Activated integrin alphavbeta3 cooperates with metalloproteinase MMP-9 in regulating migration of metastatic breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Tension development during contractile stimulation of smooth muscle requires recruitment of paxillin and vinculin to the membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Rac activation and inactivation control plasticity of tumor cell movement

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

A molecular trajectory of α-actinin activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Vinculin controls PTEN protein level by maintaining the interaction of the adherens junction protein beta-catenin with the scaffolding protein MAGI-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Vinculin modulation of paxillin-FAK interactions regulates ERK to control survival and motility.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Interaction of the 47-kDa talin fragment and the 32-kDa vinculin fragment with acidic phospholipids: a computer analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Transmembrane molecular assemblies in cell-extracellular matrix interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Vinculin-dependent Cadherin mechanosensing regulates efficient epithelial barrier formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Vinculin-deficient PC12 cell lines extend unstable lamellipodia and filopodia and have a reduced rate of neurite outgrowth

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Compensation mechanism in tumor cell migration: mesenchymal-amoeboid transition after blocking of pericellular proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Migration of tumor cells in 3D matrices is governed by matrix stiffness along with cell-matrix adhesion and proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Cardiac-myocyte-specific excision of the vinculin gene disrupts cellular junctions, causing sudden death or dilated cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

Heterozygous inactivation of the vinculin gene predisposes to stress-induced cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

The phosphorylation of vinculin on tyrosine residues 100 and 1065, mediated by SRC kinases, affects cell spreading.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

NEDD9 stabilizes focal adhesions, increases binding to the extra-cellular matrix and differentially effects 2D versus 3D cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

The structure and regulation of vinculin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

A lipid-regulated docking site on vinculin for protein kinase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCBIN.10064

21 January 2018

Identifiers

DOI

10.1002/CBIN.10064

1 reference

28 August 2017

1 reference

PubMed ID

23494917