(Q38097534)

28 August 2017

title

Pharmacogenomics of bipolar disorder (English)

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28 August 2017

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7

Maria Del Zompo

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Mirko Manchia

8

Mirko Manchia

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Claudia Pisanu

Claudia Pisanu

4

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Alessio Squassina

Alessio Squassina

2

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Stefano Calza

Stefano Calza

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author name string

Giovanni Severino

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28 August 2017

Marta Costa

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28 August 2017

Martin Alda

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28 August 2017

publication date

1 April 2013

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28 August 2017

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28 August 2017

volume

14

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28 August 2017

issue

6

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28 August 2017

page(s)

655-674

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Lifetime and 12-month prevalence of bipolar spectrum disorder in the National Comorbidity Survey replication

28 August 2017

cites work

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Prevalence and correlates of bipolar spectrum disorder in the world mental health survey initiative

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Association of mental disorders in early adulthood and later psychiatric hospital admissions and mortality in a cohort study of more than 1 million men.

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Excess mortality in bipolar and unipolar disorder in Sweden

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The lifetime cost of bipolar disorder in the US: an estimate for new cases in 1998.

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Treatment of bipolar disorder: a systematic review of available data and clinical perspectives

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Efficacy of pharmacotherapy in bipolar disorder: a report by the WPA section on pharmacopsychiatry

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Balanced efficacy, safety, and tolerability recommendations for the clinical management of bipolar disorder

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Maintenance therapies in bipolar disorders

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Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) collaborative update of CANMAT guidelines for the management of patients with bipolar disorder: update 2013.

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Comparative efficacy and acceptability of antimanic drugs in acute mania: a multiple-treatments meta-analysis

21 January 2018

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Treatment options for acute depression in bipolar disorder

21 January 2018

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Which clinical factors predict response to prophylactic lithium? A systematic review for bipolar disorders

21 January 2018

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Investigating responders to lithium prophylaxis as a strategy for mapping susceptibility genes for bipolar disorder

21 January 2018

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A consecutive series of treated affected offspring of parents with bipolar disorder: is response associated with the clinical profile?

21 January 2018

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Genetic factors and treatment of mood disorders

21 January 2018

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Factors Associated with Poor Response to Lithium Carbonate: A Clinical Study

21 January 2018

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Phenotypic spectra of bipolar disorder in responders to lithium versus lamotrigine

21 January 2018

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Neurobiology of bipolar disorder

21 January 2018

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Factors affecting fluvoxamine antidepressant activity: influence of pindolol and 5-HTTLPR in delusional and nondelusional depression

21 January 2018

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Further evidence of a combined effect of SERTPR and TPH on SSRIs response in mood disorders

21 January 2018

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The C(-1019)G polymorphism of the 5-HT1A gene promoter and antidepressant response in mood disorders: preliminary findings

21 January 2018

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HTR2A gene variation is involved in antidepressant treatment response

21 January 2018

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SSRIs antidepressant activity is influenced by G beta 3 variants

21 January 2018

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Increased temporal cortex CREB concentrations and antidepressant treatment in major depression.

21 January 2018

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Selective DNA methylation of BDNF promoter in bipolar disorder: differences among patients with BDI and BDII.

21 January 2018

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Vesicular glutamate transporter mRNA expression in the medial temporal lobe in major depressive disorder, bipolar disorder, and schizophrenia

21 January 2018

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Risk factors associated with metabolic syndrome in bipolar and schizophrenia subjects treated with antipsychotics: the role of folate pharmacogenetics

21 January 2018

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Decreased expression of Sprouty2 in the dorsolateral prefrontal cortex in schizophrenia and bipolar disorder: a correlation with BDNF expression

21 January 2018

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Proteomic analysis of human hippocampus shows differential protein expression in the different hippocampal subfields.

21 January 2018

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The DRD2/ANKK1 gene is associated with response to add-on dextromethorphan treatment in bipolar disorder.

21 January 2018

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Preliminary evidence on the association between XBP1-116C/G polymorphism and response to prophylactic treatment with valproate in bipolar disorders.

21 January 2018

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Catechol-O-methyltransferase Val158Met polymorphism affects therapeutic response to mood stabilizer in symptomatic manic patients

21 January 2018

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C825T polymorphism of the GNB3 gene on valproate-related metabolic abnormalities in bipolar disorder patients

21 January 2018

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Chromatin remodeling: a novel mechanism of psychotropic drug action

21 January 2018

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The mood stabilizers lithium and valproate selectively activate the promoter IV of brain-derived neurotrophic factor in neurons.

21 January 2018

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Histone deacetylase inhibitors and candidate gene expression: An in vivo and in vitro approach to studying chromatin remodeling in a clinical population

21 January 2018

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Regulation of glycogen synthase kinase-3 during bipolar mania treatment

21 January 2018

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Autosomal recessive inheritance of affective disorders in families of responders to lithium prophylaxis?

21 January 2018

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Further evidence for a possible association between serotonin transporter gene and lithium prophylaxis in mood disorders.

21 January 2018

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Response to lithium prophylaxis: interaction between serotonin transporter and BDNF genes.

21 January 2018

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Clinical and pathogenic aspects of candidate genes for lithium prophylactic efficacy.

21 January 2018

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Association study of the INPP1, 5HTT, BDNF, AP-2beta and GSK-3beta GENE variants and restrospectively scored response to lithium prophylaxis in bipolar disorder

21 January 2018

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No association between lithium full responders and the DRD1, DRD2, DRD3, DAT1, 5-HTTLPR and HTR2A genes in a Sardinian sample

21 January 2018

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Dopamine D1 receptor gene polymorphism is associated with prophylactic lithium response in bipolar disorder

21 January 2018

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Dopamine receptor D2 and D4 genes, GABA(A) alpha-1 subunit genes and response to lithium prophylaxis in mood disorders.

21 January 2018

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Pharmacogenetics of lithium prophylaxis in mood disorders: analysis of COMT, MAO-A, and Gbeta3 variants

21 January 2018

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No association of three GRIN2B polymorphisms with lithium response in bipolar patients.

21 January 2018

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Influence of GRIA1, GRIA2 and GRIA4 polymorphisms on diagnosis and response to treatment in patients with major depressive disorder

21 January 2018

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Stargazin modulates AMPA receptor gating and trafficking by distinct domains

21 January 2018

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The association study of three FYN polymorphisms with prophylactic lithium response in bipolar patients

21 January 2018

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Regulation of NMDA receptors by the tyrosine kinase Fyn

21 January 2018

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Family-based association study of 76 candidate genes in bipolar disorder: BDNF is a potential risk locus. Brain-derived neutrophic factor

21 January 2018

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The brain-derived neurotrophic factor gene confers susceptibility to bipolar disorder: evidence from a family-based association study.

21 January 2018

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Non-replication of the brain-derived neurotrophic factor (BDNF) association in bipolar affective disorder: a Belgian patient-control study

21 January 2018

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Meta-analysis reveals no association of the Val66Met polymorphism of brain-derived neurotrophic factor with either schizophrenia or bipolar disorder

21 January 2018

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Prophylactic lithium response and polymorphism of the brain-derived neurotrophic factor gene.

21 January 2018

1 reference

Association studies of the BDNF and the NTRK2 gene polymorphisms with prophylactic lithium response in bipolar patients

21 January 2018

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Association of BDNF gene polymorphism with bipolar disorders in Han Chinese population.

21 January 2018

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Influence of BDNF variants on diagnosis and response to treatment in patients with major depression, bipolar disorder and schizophrenia.

21 January 2018

1 reference

The pharmacogenetics of lithium response depends upon clinical co-morbidity.

21 January 2018

1 reference

Advances in myeloma genetics and prospects for pharmacogenomic testing in multiple myeloma

21 January 2018

1 reference

Identification of three polymorphisms in the translated region of PLC-gamma1 and their investigation in lithium responsive bipolar disorder.

21 January 2018

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A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder

21 January 2018

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A high-density genome scan detects evidence for a bipolar-disorder susceptibility locus on 13q32 and other potential loci on 1q32 and 18p11.2.

21 January 2018

1 reference

Interacting genes in lithium prophylaxis: preliminary results of an exploratory analysis on the role of DGKH and NR1D1 gene polymorphisms in 199 Sardinian bipolar patients.

21 January 2018

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Pleckstrin homology domains and the cytoskeleton

21 January 2018

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Expression of glycogen synthase kinase-3 isoforms in mouse tissues and their transcription in the brain.

21 January 2018

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The glamour and gloom of glycogen synthase kinase-3

21 January 2018

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GSK-3: tricks of the trade for a multi-tasking kinase

21 January 2018

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GSK3 signalling in neural development

21 January 2018

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Glycogen synthase kinase-3 (GSK3) in psychiatric diseases and therapeutic interventions

21 January 2018

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Is Glycogen Synthase Kinase-3 a Central Modulator in Mood Regulation?

21 January 2018

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A molecular mechanism for the effect of lithium on development

21 January 2018

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Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells

21 January 2018

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Glycogen synthase kinase-3beta, mood stabilizers, and neuroprotection

21 January 2018

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Nuclear receptor Rev-erbalpha is a critical lithium-sensitive component of the circadian clock

21 January 2018

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Long-term response to lithium salts in bipolar illness is influenced by the glycogen synthase kinase 3-beta -50 T/C SNP.

21 January 2018

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Response to lithium augmentation in depression is associated with the glycogen synthase kinase 3-beta -50T/C single nucleotide polymorphism.

21 January 2018

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Association study of the glycogen synthase kinase-3beta gene polymorphism with prophylactic lithium response in bipolar patients.

21 January 2018

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Functional genetic variation in the Rev-Erbα pathway and lithium response in the treatment of bipolar disorder.

21 January 2018

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Circadian genes, rhythms and the biology of mood disorders

21 January 2018

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Rapid and sustained antidepressant response with sleep deprivation and chronotherapy in bipolar disorder

21 January 2018

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Molecular components of the mammalian circadian clock

21 January 2018

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Nuclear receptor rev-erb-{alpha} circadian gene variants and lithium carbonate prophylaxis in bipolar affective disorder

21 January 2018

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A survey of genomic studies supports association of circadian clock genes with bipolar disorder spectrum illnesses and lithium response

21 January 2018

1 reference

Ziskind-Somerfeld Research Award. Protein kinase C signaling in the brain: molecular transduction of mood stabilization in the treatment of manic-depressive illness

21 January 2018

1 reference

A possible association between the -116C/G single nucleotide polymorphism of the XBP1 gene and lithium prophylaxis in bipolar disorder

21 January 2018

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Chronic pharmacological treatment with certain antidepressants alters the expression and DNA-binding activity of transcription factor AP-2

21 January 2018

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Lithium response and genetic variation in the CREB family of genes

21 January 2018

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Lithium: a key to the genetics of bipolar disorder

21 January 2018

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Implication of synapse-related genes in bipolar disorder by linkage and gene expression analyses

21 January 2018

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A genomewide association study of response to lithium for prevention of recurrence in bipolar disorder.

21 January 2018

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Identification of lithium-regulated genes in cultured lymphoblasts of lithium responsive subjects with bipolar disorder

21 January 2018

1 reference

Gene expression and association analyses of LIM (PDLIM5) in bipolar disorder and schizophrenia

21 January 2018

1 reference

PDLIM5 and susceptibility to bipolar disorder: a family-based association study and meta-analysis

21 January 2018

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Expression of HSPF1 and LIM in the lymphoblastoid cells derived from patients with bipolar disorder and schizophrenia

21 January 2018

1 reference

Molecular characterization of bipolar disorder by comparing gene expression profiles of postmortem brains of major mental disorders

21 January 2018

1 reference

Brain-derived neurotrophic factor gene expression in pediatric bipolar disorder: effects of treatment and clinical response.

21 January 2018

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Synapsin II is involved in the molecular pathway of lithium treatment in bipolar disorder

21 January 2018

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Increased ratio of anti-apoptotic to pro-apoptotic Bcl2 gene-family members in lithium-responders one month after treatment initiation

21 January 2018

1 reference

The International Consortium on Lithium Genetics (ConLiGen): an initiative by the NIMH and IGSLI to study the genetic basis of response to lithium treatment

21 January 2018

1 reference

G Protein-coupled cyclic AMP signaling in postmortem brain of subjects with mood disorders: effects of diagnosis, suicide, and treatment at the time of death.

21 January 2018

1 reference

Critical factors in gene expression in postmortem human brain: Focus on studies in schizophrenia.

21 January 2018

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Increased lactate levels and reduced pH in postmortem brains of schizophrenics: medication confounds

21 January 2018

1 reference

EBNA2 and Notch signalling in Epstein-Barr virus mediated immortalization of B lymphocytes

21 January 2018

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Epstein-Barr virus-encoded LMP1 induces a hyperproliferative and inflammatory gene expression programme in cultured keratinocytes

21 January 2018

1 reference

Realities and expectations of pharmacogenomics and personalized medicine: impact of translating genetic knowledge into clinical practice

21 January 2018

1 reference

Genetic architectures of psychiatric disorders: the emerging picture and its implications

21 January 2018

1 reference

Finding the missing heritability of complex diseases

21 January 2018

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An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people

21 January 2018

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Challenges in medical applications of whole exome/genome sequencing discoveries

21 January 2018

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Clinical application of exome sequencing in undiagnosed genetic conditions

21 January 2018

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Priorities and standards in pharmacogenetic research

21 January 2018

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Pharmacogenetics and drug development: the path to safer and more effective drugs

21 January 2018

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Lithium toxicity profile: a systematic review and meta-analysis

21 January 2018

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Duration of lithium treatment is a risk factor for reduced glomerular function: a cross-sectional study

21 January 2018

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Tryptophan hydroxylase gene associated with paroxetine antidepressant activity.

21 January 2018

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Influence of tryptophan hydroxylase and serotonin transporter genes on fluvoxamine antidepressant activity.

21 January 2018

1 reference

Influence of TPH2 variants on diagnosis and response to treatment in patients with major depression, bipolar disorder and schizophrenia.

21 January 2018

1 reference

Association analysis of group II metabotropic glutamate receptor genes (GRM2 and GRM3) with mood disorders and fluvoxamine response in a Japanese population

21 January 2018

1 reference

No association between dopamine D(2) and D(4) receptor gene variants and antidepressant activity of two selective serotonin reuptake inhibitors

21 January 2018

1 reference

DAOA variants on diagnosis and response to treatment in patients with major depressive disorder and bipolar disorder.

21 January 2018

1 reference

Association analysis of a functional G protein beta3 subunit gene polymorphism (C825T) in mood disorders

21 January 2018

1 reference

Genetic association study of treatment response with olanzapine/fluoxetine combination or lamotrigine in bipolar I depression

21 January 2018

1 reference

Harm avoidance moderates the influence of serotonin transporter gene variants on treatment outcome in bipolar patients

21 January 2018

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Role of COMT, 5-HT(1A) , and SERT genetic polymorphisms on antidepressant response to Transcranial Magnetic Stimulation

21 January 2018

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Serotonin transporter gene associated with lithium prophylaxis in mood disorders.

21 January 2018

1 reference

Genetic mapping using haplotype, association and linkage methods suggests a locus for severe bipolar disorder (BPI) at 18q22-q23.

21 January 2018

1 reference

Functional impairment in patients with mania: baseline results of the EMBLEM study

21 January 2018

1 reference

Analysis of microsatellite markers and single nucleotide polymorphisms in candidate genes for susceptibility to bipolar affective disorder in the chromosome 12Q24.31 region

21 January 2018

1 reference

The diacylglycerol kinase eta gene and bipolar disorder: a replication study in a Sardinian sample

21 January 2018

1 reference

The PDLIM5 gene and lithium prophylaxis: An association and gene expression analysis in Sardinian patients with bipolar disorder

21 January 2018

1 reference

Evidence for association of anACCN1gene variant with response to lithium treatment in Sardinian patients with bipolar disorder

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.2217/PGS.13.51

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28 August 2017

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