(Q38104416)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23647299%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

title

Molecular networks in melanoma invasion and metastasis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23647299%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23647299%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

author name string

Ewa Aladowicz

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23647299%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Leda Ferro

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23647299%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Giulio Cesare Vitali

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23647299%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Elisabetta Venditti

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23647299%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Lorenzo Fornasari

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23647299%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

language of work or name

English

0 references

publication date

1 May 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23647299%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23647299%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

volume

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23647299%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23647299%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

page(s)

713-726

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23647299%20AND%20SRC:MED&resulttype=core&format=json

Estimates of cancer incidence and mortality in Europe in 2008.

29 February 2020

cites work

1 reference

Annual report to the nation on the status of cancer (1973 through 1998), featuring cancers with recent increasing trends

21 January 2018

1 reference

Final version of 2009 AJCC melanoma staging and classification

21 January 2018

1 reference

Re-evaluating the role of dacarbazine in metastatic melanoma: what have we learned in 30 years?

21 January 2018

1 reference

L-tyrosine and L-dihydroxyphenylalanine as hormone-like regulators of melanocyte functions

21 January 2018

1 reference

How to make a melanoma: what do we know of the primary clonal events?

21 January 2018

1 reference

β-catenin signaling controls metastasis in Braf-activated Pten-deficient melanomas

21 January 2018

1 reference

NRAS and BRAF mutations in melanoma tumours in relation to clinical characteristics: a study based on mutation screening by pyrosequencing.

21 January 2018

1 reference

BRAF/NRAS mutation frequencies among primary tumors and metastases in patients with melanoma.

21 January 2018

1 reference

A landscape of driver mutations in melanoma

21 January 2018

1 reference

Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma.

21 January 2018

1 reference

Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing

21 January 2018

1 reference

Frequencies of NRAS and BRAF mutations increase from the radial to the vertical growth phase in cutaneous melanoma

21 January 2018

1 reference

Deletion at chromosome arm 9p in relation to BRAF/NRAS mutations and prognostic significance for primary melanoma

21 January 2018

1 reference

A comprehensive catalogue of somatic mutations from a human cancer genome

21 January 2018

1 reference

Intratumoral molecular heterogeneity in a BRAF-mutant, BRAF inhibitor-resistant melanoma: a case illustrating the challenges for personalized medicine.

21 January 2018

1 reference

The melanocyte differentiation program predisposes to metastasis after neoplastic transformation

21 January 2018

1 reference

Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma

21 January 2018

1 reference

Cadherin switch from E- to N-cadherin in melanoma progression is regulated by the PI3K/PTEN pathway through Twist and Snail

21 January 2018

1 reference

Transcriptional activation of ZEB1 by Slug leads to cooperative regulation of the epithelial-mesenchymal transition-like phenotype in melanoma

21 January 2018

1 reference

MITF: master regulator of melanocyte development and melanoma oncogene

21 January 2018

1 reference

Intravital imaging reveals transient changes in pigment production and Brn2 expression during metastatic melanoma dissemination

21 January 2018

1 reference

The metastasis gene NEDD9 product acts through integrin β3 and Src to promote mesenchymal motility and inhibit amoeboid motility

21 January 2018

1 reference

Rac activation and inactivation control plasticity of tumor cell movement

21 January 2018

1 reference

Phenotypic heterogeneity among tumorigenic melanoma cells from patients that is reversible and not hierarchically organized

21 January 2018

1 reference

Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature

21 January 2018

1 reference

In vivo switching of human melanoma cells between proliferative and invasive states

21 January 2018

1 reference

Mitf regulation of Dia1 controls melanoma proliferation and invasiveness

21 January 2018

1 reference

Melanoma and the tumor microenvironment

21 January 2018

1 reference

Transcriptional control of melanoma metastasis: the importance of the tumor microenvironment

21 January 2018

1 reference

21 January 2018

1 reference

The role of altered cell-cell communication in melanoma progression

21 January 2018

1 reference

Adherens junctions: from molecules to morphogenesis

21 January 2018

1 reference

GSK3β inhibition blocks melanoma cell/host interactions by downregulating N-cadherin expression and decreasing FAK phosphorylation

21 January 2018

1 reference

MicroRNA-9 up-regulates E-cadherin through inhibition of NF-κB1-Snail1 pathway in melanoma

21 January 2018

1 reference

The epithelial-mesenchymal transition (EMT) regulatory factor SLUG (SNAI2) is a downstream target of SPARC and AKT in promoting melanoma cell invasion

21 January 2018

1 reference

Adhesion, migration and communication in melanocytes and melanoma

21 January 2018

1 reference

Cell adhesion and signalling by cadherins and Ig-CAMs in cancer

21 January 2018

1 reference

Expression of Id-1 is regulated by MCAM/MUC18: a missing link in melanoma progression

21 January 2018

1 reference

Ectodomain shedding of L1 adhesion molecule promotes cell migration by autocrine binding to integrins

21 January 2018

1 reference

The adhesion molecule L1 (CD171) promotes melanoma progression

21 January 2018

1 reference

Adhesion molecule signalling: not always a sticky business.

21 January 2018

1 reference

Integrins: versatile receptors controlling melanocyte adhesion, migration and proliferation

21 January 2018

1 reference

The ins and outs of leukocyte integrin signaling

21 January 2018

1 reference

Integrins in cancer: biological implications and therapeutic opportunities

21 January 2018

1 reference

Phosphorylation of ectopically expressed L-plastin enhances invasiveness of human melanoma cells

21 January 2018

1 reference

Tumour progression and metastatic behaviour in vivo correlates with integrin expression on melanocytic tumours.

21 January 2018

1 reference

Proteomic analysis of α4β1 integrin adhesion complexes reveals α-subunit-dependent protein recruitment

21 January 2018

1 reference

Processing of MIA protein during melanoma cell migration.

21 January 2018

1 reference

Multimodality tumor imaging targeting integrin alphavbeta3.

21 January 2018

1 reference

Matrix metalloproteinase-2 promotes αvβ3 integrin-mediated adhesion and migration of human melanoma cells by cleaving fibronectin

21 January 2018

1 reference

A randomized phase II study of cilengitide (EMD 121974) in patients with metastatic melanoma.

21 January 2018

1 reference

MMP-1: the elder of the family

21 January 2018

1 reference

Suppression of basement membrane type IV collagen degradation and cell invasion in human melanoma cells expressing an antisense RNA for MMP-1.

21 January 2018

1 reference

Galectin-3 increases the motility of mouse melanoma cells by regulating matrix metalloproteinase-1 expression.

21 January 2018

1 reference

Induction of secreted matrix metalloproteinase-9 activity in human melanoma cells by extracellular matrix proteins and cytokines.

21 January 2018

1 reference

Phase II study of marimastat (BB-2516) in malignant melanoma: a clinical and tumor biopsy study of the National Cancer Institute of Canada Clinical Trials Group

21 January 2018

1 reference

Phase I and pharmacokinetic study of continuous twice weekly intravenous administration of Cilengitide (EMD 121974), a novel inhibitor of the integrins αvβ3 and αvβ5 in patients with advanced solid tumours

21 January 2018

1 reference

CNTO 95, a fully human monoclonal antibody that inhibits alphav integrins, has antitumor and antiangiogenic activity in vivo

21 January 2018

1 reference

Clinical and pharmacologic evaluation of two dose levels of intetumumab (CNTO 95) in patients with melanoma or angiosarcoma.

21 January 2018

1 reference

Rho protein crosstalk: another social network?

21 January 2018

1 reference

Rho GTPases and their effector proteins

21 January 2018

1 reference

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

21 January 2018

1 reference

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

21 January 2018

1 reference

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

21 January 2018

1 reference

The molecular mechanisms of transition between mesenchymal and amoeboid invasiveness in tumor cells.

21 January 2018

1 reference

Compensation mechanism in tumor cell migration: mesenchymal-amoeboid transition after blocking of pericellular proteolysis

21 January 2018

1 reference

Differing modes of tumour cell invasion have distinct requirements for Rho/ROCK signalling and extracellular proteolysis

21 January 2018

1 reference

DOCK10-mediated Cdc42 activation is necessary for amoeboid invasion of melanoma cells

21 January 2018

1 reference

Cellular heterogeneity during embryonic stem cell differentiation to epiblast stem cells is revealed by the ShcD/RaLP adaptor protein

21 January 2018

1 reference

Expression patterns of ShcD and Shc family adaptor proteins during mouse embryonic development.

21 January 2018

1 reference

Transcriptomic analysis of mouse embryonic skin cells reveals previously unreported genes expressed in melanoblasts

21 January 2018

1 reference

Analysis of a Shc family adaptor protein, ShcD/Shc4, that associates with muscle-specific kinase

21 January 2018

1 reference

RaLP, a new member of the Src homology and collagen family, regulates cell migration and tumor growth of metastatic melanomas

21 January 2018

1 reference

The migratory pathway of neural crest cells into the skin of mouse embryos

21 January 2018

1 reference

Neural crest delamination and migration: from epithelium-to-mesenchyme transition to collective cell migration

21 January 2018

1 reference

Melanoma revives an embryonic migration program to promote plasticity and invasion

21 January 2018

1 reference

Inverse expression states of the BRN2 and MITF transcription factors in melanoma spheres and tumour xenografts regulate the NOTCH pathway

21 January 2018

1 reference

The Brn-2 transcription factor links activated BRAF to melanoma proliferation

21 January 2018

1 reference

Brn-2 expression controls melanoma proliferation and is directly regulated by beta-catenin

21 January 2018

1 reference

GLI2 and M-MITF transcription factors control exclusive gene expression programs and inversely regulate invasion in human melanoma cells

21 January 2018

1 reference

Expression of microphthalmia-associated transcription factor (MITF), which is critical for melanoma progression, is inhibited by both transcription factor GLI2 and transforming growth factor-β.

21 January 2018

1 reference

GLI2-mediated melanoma invasion and metastasis

21 January 2018

1 reference

Whole-genome expression profiling of the melanoma progression pathway reveals marked molecular differences between nevi/melanoma in situ and advanced-stage melanomas

21 January 2018

1 reference

Gene expression profiling-based identification of molecular subtypes in stage IV melanomas with different clinical outcome.

21 January 2018

1 reference

Immune profile and mitotic index of metastatic melanoma lesions enhance clinical staging in predicting patient survival

21 January 2018

1 reference

Molecular profiling reveals low- and high-grade forms of primary melanoma

21 January 2018

1 reference

Inhibitors of melanogenesis increase toxicity of cyclophosphamide and lymphocytes against melanoma cells

21 January 2018

1 reference

Role of the endothelin axis and its antagonists in the treatment of cancer

21 January 2018

1 reference

Piebald lethal (sl) acts early to disrupt the development of neural crest-derived melanocytes

21 January 2018

1 reference

Interaction of endothelin-3 with endothelin-B receptor is essential for development of epidermal melanocytes and enteric neurons

21 January 2018

1 reference

The endothelin receptor-B is required for the migration of neural crest-derived melanocyte and enteric neuron precursors.

21 January 2018

1 reference

The temporal requirement for endothelin receptor-B signalling during neural crest development

21 January 2018

1 reference

An endothelin receptor B antagonist inhibits growth and induces cell death in human melanoma cells in vitro and in vivo

21 January 2018

1 reference

UV-induction of keratinocyte endothelin-1 downregulates E-cadherin in melanocytes and melanoma cells

21 January 2018

1 reference

Endothelin B receptor blockade inhibits dynamics of cell interactions and communications in melanoma cell progression.

21 January 2018

1 reference

Endothelin-1 inhibits prolyl hydroxylase domain 2 to activate hypoxia-inducible factor-1alpha in melanoma cells

21 January 2018

1 reference

A phase II study of bosentan, a dual endothelin receptor antagonist, as monotherapy in patients with stage IV metastatic melanoma

21 January 2018

1 reference

A randomized, double-blind, placebo-controlled study of high-dose bosentan in patients with stage IV metastatic melanoma receiving first-line dacarbazine chemotherapy

21 January 2018

1 reference

Roles for endothelin receptor B and BCL2A1 in spontaneous CNS metastasis of melanoma

21 January 2018

1 reference

Targeted Therapy Database (TTD): a model to match patient's molecular profile with current knowledge on cancer biology

21 January 2018

1 reference

21 January 2018

1 reference

Brn-2 Represses Microphthalmia-Associated Transcription Factor Expression and Marks a Distinct Subpopulation of Microphthalmia-Associated Transcription Factor-Negative Melanoma Cells

21 January 2018

1 reference

Comparative Oncogenomics Identifies NEDD9 as a Melanoma Metastasis Gene

21 January 2018

1 reference

Melanoma: targeting signaling pathways and RaLP

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.2217/FON.13.9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23647299%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference