(Q38105645)

28 August 2017

The hallmarks of Parkinson's disease (English)

1 reference

28 August 2017

1 reference

4

Rudi Balling

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28 August 2017

3

Rejko Krüger

1 reference

28 August 2017

Paul M A Antony

1

1 reference

PubMed ID

23663200

28 August 2017

Nico J Diederich

series ordinal

2

1 reference

PubMed ID

23663200

28 August 2017

language of work or name

English

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publication date

10 June 2013

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28 August 2017

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28 August 2017

280

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28 August 2017

23

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28 August 2017

5981-5993

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Hypokinesia without decrement distinguishes progressive supranuclear palsy from Parkinson's disease

28 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

What are the most important nonmotor symptoms in patients with Parkinson's disease and are we missing them?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Non-motor symptoms in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Identifying prodromal Parkinson's disease: pre-motor disorders in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

21 January 2018

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Hallmarks of Cancer: The Next Generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Epidemiology of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Alzheimer's disease and Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Parkinson disease: insights in clinical, genetic and pathological features of monogenic disease subtypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Ageing, neurodegeneration and Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Genetics of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

The genetics of Parkinson's disease: progress and therapeutic implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

LRRK2 G2019S as a cause of Parkinson's disease in Ashkenazi Jews.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Inhibition of mitochondrial respiration by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in mouse brain in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Environmental risk factors and Parkinson's disease: a metaanalysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Neurotoxicant-induced animal models of Parkinson's disease: understanding the role of rotenone, maneb and paraquat in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Parkinson's disease: evidence for environmental risk factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Trichloroethylene: Parkinsonism and complex 1 mitochondrial neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Solvent exposures and Parkinson disease risk in twins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Epidemiology and etiology of Parkinson's disease: a review of the evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Genome-wide association study reveals genetic risk underlying Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Gaucher disease glucocerebrosidase and α-synuclein form a bidirectional pathogenic loop in synucleinopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Staging of brain pathology related to sporadic Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Parkinson's disease: the dual hit theory revisited

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Is Parkinson's disease a prion disorder?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Pathological α-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Exogenous α-synuclein fibrils induce Lewy body pathology leading to synaptic dysfunction and neuron death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Environmental toxins trigger PD-like progression via increased alpha-synuclein release from enteric neurons in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Progression of Parkinson's disease pathology is reproduced by intragastric administration of rotenone in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Mechanisms of cross-talk between the ubiquitin-proteasome and autophagy-lysosome systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Alterations in lysosomal and proteasomal markers in Parkinson's disease: relationship to alpha-synuclein inclusions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Lysosomal dysfunction in Parkinson disease: ATP13A2 gets into the groove

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Silencing of PINK1 expression affects mitochondrial DNA and oxidative phosphorylation in dopaminergic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Bioenergetic consequences of PINK1 mutations in Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Oxidative insults induce DJ-1 upregulation and redistribution: implications for neuroprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Oxidative stress induction of DJ-1 protein in reactive astrocytes scavenges free radicals and reduces cell injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Mitochondrial biology and Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Monogenic mitochondrial disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Mitochondrial dysfunction in Parkinson's disease: molecular mechanisms and pathophysiological consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Single nigrostriatal dopaminergic neurons form widely spread and highly dense axonal arborizations in the neostriatum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Living on the edge with too many mouths to feed: why dopamine neurons die.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Mitochondria mass is low in mouse substantia nigra dopamine neurons: implications for Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Neuronal vulnerability, pathogenesis, and Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

The pathology roadmap in Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Cell metabolism affects selective vulnerability in PINK1-associated Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

A molecular basis for the increased vulnerability of substantia nigra dopamine neurons in aging and Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Evaluation of a multi-parameter biomarker set for oxidative damage in man: increased urinary excretion of lipid, protein and DNA oxidation products after one hour of exercise.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Mitochondrial formation of reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Mitochondrial complex I deficiency in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Oxidative stress in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Phosphorus and proton magnetic resonance spectroscopy demonstrates mitochondrial dysfunction in early and advanced Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Structure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Keap1/Nrf2 system regulates neuronal survival as revealed through study of keap1 gene-knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

The Nrf2-Keap1-ARE signaling pathway: The regulation and dual function of Nrf2 in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Somatic mitochondrial DNA mutations in early Parkinson and incidental Lewy body disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Genetics and iron in the systems biology of Parkinson's disease and some related disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

The Haber-Weiss reaction and mechanisms of toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

The effect of age on the non-haemin iron in the human brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Distribution of iron in different brain regions and subcellular compartments in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Iron-melanin interaction and lipid peroxidation: implications for Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Transcranial ultrasound in different monogenetic subtypes of Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Increased iron levels correlate with the selective nigral dopaminergic neuron degeneration in Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Iron dysregulation in movement disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

ATP13A2 mutations (PARK9) cause neurodegeneration with brain iron accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

PLA2G6 mutations and other rare causes of neurodegeneration with brain iron accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examples

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Metals, oxidative stress and neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Chelating agents for neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Multiple hit hypotheses for dopamine neuron loss in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Ubiquitin, the proteasome and protein degradation in neuronal function and dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Neural activity controls the synaptic accumulation of alpha-synuclein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Increased expression of alpha-synuclein reduces neurotransmitter release by inhibiting synaptic vesicle reclustering after endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

From α-synuclein to synaptic dysfunctions: new insights into the pathophysiology of Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Immune activation in brain aging and neurodegeneration: too much or too little?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Neuronal regulation of immune responses in the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Parkinson's disease mouse models in translational research

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Aggregated alpha-synuclein activates microglia: a process leading to disease progression in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Alpha-synuclein release by neurons activates the inflammatory response in a microglial cell line.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Mechanisms underlying inflammation in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Astrocyte-derived GDNF is a potent inhibitor of microglial activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Regulation of astrocyte inflammatory responses by the Parkinson's disease-associated gene DJ-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Glial cells as players in parkinsonism: the "good," the "bad," and the "mysterious" glia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Human neuromelanin induces neuroinflammation and neurodegeneration in the rat substantia nigra: implications for Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Regulatory T cells attenuate Th17 cell-mediated nigrostriatal dopaminergic neurodegeneration in a model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Neuroinflammation in Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

From systems biology to systems biomedicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Introduction to network analysis in systems biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

The control systems structures of energy metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

An energy systems approach to Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Bidirectional coupling between astrocytes and neurons mediates learning and dynamic coordination in the brain: a multiple modeling approach.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Brain lactate kinetics: Modeling evidence for neuronal lactate uptake upon activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Tripartite synapses: astrocytes process and control synaptic information

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Light microscopy applications in systems biology: opportunities and challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Induced pluripotent stem cell research: a revolutionary approach to face the challenges in drug screening.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

Mitochondrial dysfunction in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12335

21 January 2018

Identifiers

DOI

10.1111/FEBS.12335

1 reference

28 August 2017

1 reference

PubMed ID

23663200