(Q38105988)

28 August 2017

title

Review: the role of microRNAs in osteoarthritis and chondrogenesis (English)

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28 August 2017

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cartilage development

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Linh T T Le

1

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28 August 2017

Tracey E Swingler

series ordinal

2

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28 August 2017

Ian M Clark

series ordinal

3

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28 August 2017

language of work or name

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1 August 2013

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28 August 2017

published in

Arthritis & Rheumatology

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28 August 2017

volume

65

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28 August 2017

issue

8

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28 August 2017

page(s)

1963-1974

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Cartilage biology, pathology, and repair.

28 August 2017

cites work

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The control of chondrogenesis

21 January 2018

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The combination of SOX5, SOX6, and SOX9 (the SOX trio) provides signals sufficient for induction of permanent cartilage

21 January 2018

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Epigenetic mechanisms in cartilage and osteoarthritis: DNA methylation, histone modifications and microRNAs.

21 January 2018

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Osteoarthritis: a disease of the joint as an organ

21 January 2018

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Macro view of microRNA function in osteoarthritis

21 January 2018

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Assessment of the profiling microRNA expression of differentiated and dedifferentiated human adult articular chondrocytes

21 January 2018

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MicroRNA-140 is expressed in differentiated human articular chondrocytes and modulates interleukin-1 responses

21 January 2018

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The cartilage specific microRNA-140 targets histone deacetylase 4 in mouse cells

21 January 2018

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MicroRNA-140 plays dual roles in both cartilage development and homeostasis

21 January 2018

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Chondrocyte-specific microRNA-140 regulates endochondral bone development and targets Dnpep to modulate bone morphogenetic protein signaling.

21 January 2018

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The expression and function of microRNAs in chondrogenesis and osteoarthritis.

21 January 2018

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Epigenomic and microRNA-mediated regulation in cartilage development, homeostasis, and osteoarthritis

21 January 2018

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Mutations that lead to reiterations in the cell lineages of C. elegans

21 January 2018

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The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

21 January 2018

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Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

21 January 2018

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The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans

21 January 2018

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Identification of novel genes coding for small expressed RNAs

21 January 2018

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An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans

21 January 2018

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An extensive class of small RNAs in Caenorhabditis elegans

21 January 2018

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MicroRNAs: genomics, biogenesis, mechanism, and function

21 January 2018

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miRBase: integrating microRNA annotation and deep-sequencing data

21 January 2018

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Most mammalian mRNAs are conserved targets of microRNAs

21 January 2018

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Real-time quantification of microRNAs by stem-loop RT-PCR

21 January 2018

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MicroRNA control of signal transduction

21 January 2018

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Identification of mammalian microRNA host genes and transcription units

21 January 2018

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MicroRNA maturation: stepwise processing and subcellular localization

21 January 2018

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MicroRNA genes are transcribed by RNA polymerase II

21 January 2018

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Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs

21 January 2018

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The Drosha-DGCR8 complex in primary microRNA processing

21 January 2018

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Nuclear export of microRNA precursors

21 January 2018

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TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing

21 January 2018

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Argonaute proteins: key players in RNA silencing

21 January 2018

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Functional siRNAs and miRNAs Exhibit Strand Bias

21 January 2018

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Tissue-dependent paired expression of miRNAs

21 January 2018

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Micro RNAs are complementary to 3' UTR sequence motifs that mediate negative post-transcriptional regulation

21 January 2018

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The biogenesis and characterization of mammalian microRNAs of mirtron origin.

21 January 2018

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The molecular machines that mediate microRNA maturation

21 January 2018

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Target mRNAs are repressed as efficiently by microRNA-binding sites in the 5' UTR as in the 3' UTR

21 January 2018

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Principles of microRNA-target recognition

21 January 2018

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Regulation of mRNA translation and stability by microRNAs

21 January 2018

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Switching from repression to activation: microRNAs can up-regulate translation

21 January 2018

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AU-rich-element-mediated upregulation of translation by FXR1 and Argonaute 2.

21 January 2018

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The RNaseIII enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb

21 January 2018

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Dicer-dependent pathways regulate chondrocyte proliferation and differentiation

21 January 2018

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The microRNA-producing enzyme Dicer1 is essential for zebrafish development

21 January 2018

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Isolation and characterization of CD146+ multipotent mesenchymal stromal cells.

21 January 2018

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miR-199a, a bone morphogenic protein 2-responsive MicroRNA, regulates chondrogenesis via direct targeting to Smad1

21 January 2018

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MicroRNA regulation associated chondrogenesis of mouse MSCs grown on polyhydroxyalkanoates

21 January 2018

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MicroRNA-145 regulates chondrogenic differentiation of mesenchymal stem cells by targeting Sox9.

21 January 2018

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Regulation of human chondrocyte function through direct inhibition of cartilage master regulator SOX9 by microRNA-145 (miRNA-145)

21 January 2018

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Type II collagen expression is regulated by tissue-specific miR-675 in human articular chondrocytes.

21 January 2018

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Experimental identification of microRNA-140 targets by silencing and overexpressing miR-140.

21 January 2018

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Analyzing mRNA expression identifies Smad3 as a microRNA-140 target regulated only at protein level.

21 January 2018

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L-Sox5 and Sox6 proteins enhance chondrogenic miR-140 microRNA expression by strengthening dimeric Sox9 activity

21 January 2018

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MiR-140 is co-expressed with Wwp2-C transcript and activated by Sox9 to target Sp1 in maintaining the chondrocyte proliferation.

21 January 2018

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MiR-194 regulates chondrogenic differentiation of human adipose-derived stem cells by targeting Sox5

21 January 2018

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MicroRNA-337 is associated with chondrogenesis through regulating TGFBR2 expression.

21 January 2018

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MicroRNA-34a regulates migration of chondroblast and IL-1β-induced degeneration of chondrocytes by targeting EphA5.

21 January 2018

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MicroRNA-221 regulates chondrogenic differentiation through promoting proteosomal degradation of slug by targeting Mdm2

21 January 2018

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MicroRNA-34a modulates cytoskeletal dynamics through regulating RhoA/Rac1 cross-talk in chondroblasts

21 January 2018

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MicroRNA-488 suppresses cell migration through modulation of the focal adhesion activity during chondrogenic differentiation of chick limb mesenchymal cells.

21 January 2018

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MicroRNA-142-3p regulates TGF-β3-mediated region-dependent chondrogenesis by regulating ADAM9.

21 January 2018

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Integrative microRNA and proteomic approaches identify novel osteoarthritis genes and their collaborative metabolic and inflammatory networks

21 January 2018

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The identification of differentially expressed microRNA in osteoarthritic tissue that modulate the production of TNF-alpha and MMP13.

21 January 2018

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Characterization of microRNA expression profiles in normal and osteoarthritic human chondrocytes.

21 January 2018

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Regulation of the IGFBP-5 and MMP-13 genes by the microRNAs miR-140 and miR-27a in human osteoarthritic chondrocytes

21 January 2018

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MiRNA-140 is a negative feedback regulator of MMP-13 in IL-1β-stimulated human articular chondrocyte C28/I2 cells

21 January 2018

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miR-27a is a negative regulator of adipocyte differentiation via suppressing PPARgamma expression

21 January 2018

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MicroRNA-27b regulates the expression of matrix metalloproteinase 13 in human osteoarthritis chondrocytes.

21 January 2018

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Expression of MicroRNA-146a in osteoarthritis cartilage

21 January 2018

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miR-146a, an IL-1β responsive miRNA, induces vascular endothelial growth factor and chondrocyte apoptosis by targeting Smad4.

21 January 2018

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MicroRNA-146a is linked to pain-related pathophysiology of osteoarthritis

21 January 2018

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Mechanotransduction of bovine articular cartilage superficial zone protein by transforming growth factor beta signaling

21 January 2018

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MiR-365: a mechanosensitive microRNA stimulates chondrocyte differentiation through targeting histone deacetylase 4.

21 January 2018

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Profiling microRNA expression in bovine articular cartilage and implications for mechanotransduction

21 January 2018

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Osteoarthritis as an inflammatory disease (osteoarthritis is not osteoarthrosis!).

21 January 2018

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What do microRNAs mean for rheumatoid arthritis?

21 January 2018

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MicroRNA-155 as a proinflammatory regulator in clinical and experimental arthritis

21 January 2018

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Innate immune system activation in osteoarthritis: is osteoarthritis a chronic wound?

21 January 2018

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Analysing the role of endogenous matrix molecules in the development of osteoarthritis.

21 January 2018

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NF-kappaB signaling: multiple angles to target OA.

21 January 2018

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Molecular network of cartilage homeostasis and osteoarthritis

21 January 2018

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MicroRNA-155 modulates the interleukin-1 signaling pathway in activated human monocyte-derived dendritic cells

21 January 2018

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NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses

21 January 2018

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Changes in microRNA expression in peripheral mononuclear cells according to the progression of osteoarthritis.

21 January 2018

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Serum microRNAs are promising novel biomarkers

21 January 2018

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Circulating microRNA in body fluid: a new potential biomarker for cancer diagnosis and prognosis

21 January 2018

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Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma

21 January 2018

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Detection of elevated levels of tumour-associated microRNAs in serum of patients with diffuse large B-cell lymphoma

21 January 2018

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Plasma and synovial fluid microRNAs as potential biomarkers of rheumatoid arthritis and osteoarthritis

21 January 2018

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Osteoarthritis - an untreatable disease?

21 January 2018

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LNA-mediated microRNA silencing in non-human primates

21 January 2018

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The effect of microRNA-21 on proliferation and matrix synthesis of chondrocytes embedded in atelocollagen gel.

21 January 2018

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Genome-wide miRNA signatures of human longevity.

21 January 2018

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microRNA expression patterns reveal differential expression of target genes with age.

21 January 2018

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21 January 2018

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Synergistic collagenase expression and cartilage collagenolysis are phosphatidylinositol 3-kinase/Akt signaling-dependent.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/ART.37990

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28 August 2017

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