(Q38106675)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23671130%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

title

Metastasis suppressor, NDRG1, mediates its activity through signaling pathways and molecular motors (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23671130%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

0 references

11

1 reference

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1 March 2020

Dong-Hun Bae

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23671130%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Sumit Sahni

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23671130%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

author name string

Jing Sun

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23671130%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Daohai Zhang

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23671130%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Patric Jansson

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23671130%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Ying Zheng

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23671130%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Qian Zhao

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23671130%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Fei Yue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23671130%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Minhua Zheng

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23671130%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Zaklina Kovacevic

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23671130%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

language of work or name

English

0 references

publication date

13 May 2013

1 reference

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1 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23671130%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

volume

34

1 reference

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1 March 2020

issue

9

1 reference

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1 March 2020

page(s)

1943-1954

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23671130%20AND%20SRC:MED&resulttype=core&format=json

The metastasis suppressor, Ndrg-1: a new ally in the fight against cancer

1 March 2020

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Drg1 expression in 131 colorectal liver metastases: correlation with clinical variables and patient outcomes

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Hypoxia induces the expression of a 43-kDa protein (PROXY-1) in normal and malignant cells

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NDRG1, a growth and cancer related gene: regulation of gene expression and function in normal and disease states

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Identification of NDRG1-regulated genes associated with invasive potential in cervical and ovarian cancer cells

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Role of the putative tumor metastasis suppressor gene Drg-1 in breast cancer progression.

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N-myc downstream-regulated gene 1 (NDRG1) a differentiation marker of human breast cancer

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NDRG1/2 expression is inhibited in primary acute myeloid leukemia

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Characterization of the human NDRG gene family: a newly identified member, NDRG4, is specifically expressed in brain and heart

21 January 2018

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Tumor growth suppression in pancreatic cancer by a putative metastasis suppressor gene Cap43/NDRG1/Drg-1 through modulation of angiogenesis

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Cellular differentiation determines the expression of the hypoxia-inducible protein NDRG1 in pancreatic cancer.

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Transcriptional silencing of N-Myc downstream-regulated gene 1 (NDRG1) in metastatic colon cancer cell line SW620.

21 January 2018

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The growth-inhibitory Ndrg1 gene is a Myc negative target in human neuroblastomas and other cell types with overexpressed N- or c-myc

21 January 2018

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Downregulation of Cap43 gene by von Hippel-Lindau tumor suppressor protein in human renal cancer cells

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NDRG1 and CRK-I/II are regulators of endothelial cell migration under Intermittent Hypoxia

21 January 2018

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Hypoxia upregulates the expression of the NDRG1 gene leading to its overexpression in various human cancers

21 January 2018

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Nitric oxide suppresses tumor cell migration through N-Myc downstream-regulated gene-1 (NDRG1) expression: role of chelatable iron

21 January 2018

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NDRG1 is down-regulated in the early apoptotic event induced by camptothecin analogs: the potential role in proteolytic activation of PKC delta and apoptosis

21 January 2018

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NDRG1 is necessary for p53-dependent apoptosis

21 January 2018

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p53-dependent NDRG1 expression induces inhibition of intestinal epithelial cell proliferation but not apoptosis after polyamine depletion

21 January 2018

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The tumor metastasis suppressor gene Drg-1 down-regulates the expression of activating transcription factor 3 in prostate cancer.

21 January 2018

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NF-kappaB represses E-cadherin expression and enhances epithelial to mesenchymal transition of mammary epithelial cells: potential involvement of ZEB-1 and ZEB-2.

21 January 2018

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Phosphorylation of NDRG1 is temporally and spatially controlled during the cell cycle.

21 January 2018

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Expression of NDRG1, a differentiation-related gene, in human tissues

21 January 2018

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NDRG1 contributes to retinoic acid-induced differentiation of leukemic cells

21 January 2018

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Prognostic value of NDRG1 and SPARC protein expression in breast cancer patients.

21 January 2018

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Cap43/NDRG1/Drg-1 is a molecular target for angiogenesis and a prognostic indicator in cervical adenocarcinoma.

21 January 2018

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N-myc downregulated gene 1 is a phosphorylated protein in mast cells

21 January 2018

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The effect of potent iron chelators on the regulation of p53: examination of the expression, localization and DNA-binding activity of p53 and the transactivation of WAF1.

21 January 2018

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Potent iron chelators increase the mRNA levels of the universal cyclin-dependent kinase inhibitor p21(CIP1/WAF1), but paradoxically inhibit its translation: a potential mechanism of cell cycle dysregulation

21 January 2018

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The iron chelators Dp44mT and DFO inhibit TGF-β-induced epithelial-mesenchymal transition via up-regulation of N-Myc downstream-regulated gene 1 (NDRG1).

21 January 2018

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N-myc downstream regulated gene 1 modulates Wnt-β-catenin signalling and pleiotropically suppresses metastasis

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N-Myc down-regulated gene 1 mediates proliferation, invasion, and apoptosis of hepatocellular carcinoma cells

21 January 2018

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KAI1 gene is engaged in NDRG1 gene-mediated metastasis suppression through the ATF3-NFkappaB complex in human prostate cancer

21 January 2018

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N-myc downstream regulated gene 1/Cap43 suppresses tumor growth and angiogenesis of pancreatic cancer through attenuation of inhibitor of kappaB kinase beta expression

21 January 2018

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PTEN up-regulates the tumor metastasis suppressor gene Drg-1 in prostate and breast cancer.

21 January 2018

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The p85beta regulatory subunit of PI3K serves as a substrate for PTEN protein phosphatase activity during insulin mediated signaling

21 January 2018

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Protor-1 is required for efficient mTORC2-mediated activation of SGK1 in the kidney

21 January 2018

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The iron-regulated metastasis suppressor NDRG1 targets NEDD4L, PTEN, and SMAD4 and inhibits the PI3K and Ras signaling pathways

21 January 2018

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21 January 2018

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21 January 2018

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Enhanced TLR-induced NF-κB signaling and type I interferon responses in NLRC5 deficient mice

21 January 2018

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TNF-alpha/NF-kappaB/Snail pathway in cancer cell migration and invasion

21 January 2018

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Upregulation of Twist-1 by NF-kappaB blocks cytotoxicity induced by chemotherapeutic drugs

21 January 2018

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β-Catenin and NF-κB cooperate to regulate the uPA/uPAR system in cancer cells

21 January 2018

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Thioredoxin stimulates MMP-9 expression, de-regulates the MMP-9/TIMP-1 equilibrium and promotes MMP-9 dependent invasion in human MDA-MB-231 breast cancer cells

21 January 2018

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Apelin-APJ induces ICAM-1, VCAM-1 and MCP-1 expression via NF-κB/JNK signal pathway in human umbilical vein endothelial cells.

21 January 2018

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The p65 subunit of NF-κB and PARP1 assist Snail1 in activating fibronectin transcription

21 January 2018

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TNF induces caspase-dependent inflammation in renal endothelial cells through a Rho- and myosin light chain kinase-dependent mechanism.

21 January 2018

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Induction of caspase mediated apoptosis and down-regulation of nuclear factor-κB and Akt signaling are involved in the synergistic antitumor effect of gemcitabine and the histone deacetylase inhibitor trichostatin A in human bladder cancer cells.

21 January 2018

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Vimentin and PSF act in concert to regulate IbeA+ E. coli K1 induced activation and nuclear translocation of NF-κB in human brain endothelial cells

21 January 2018

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Chemotherapy-induced CXC-chemokine/CXC-chemokine receptor signaling in metastatic prostate cancer cells confers resistance to oxaliplatin through potentiation of nuclear factor-kappaB transcription and evasion of apoptosis.

21 January 2018

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Identification of sites subjected to serine/threonine phosphorylation by SGK1 affecting N-myc downstream-regulated gene 1 (NDRG1)/Cap43-dependent suppression of angiogenic CXC chemokine expression in human pancreatic cancer cells

21 January 2018

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The PTEN/PI3K/AKT signalling pathway in cancer, therapeutic implications

21 January 2018

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Targeting PI3K signalling in cancer: opportunities, challenges and limitations

21 January 2018

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Cellular function of phosphoinositide 3-kinases: implications for development, homeostasis, and cancer.

21 January 2018

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The phosphoinositide 3-kinase pathway

21 January 2018

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Rictor and integrin-linked kinase interact and regulate Akt phosphorylation and cancer cell survival

21 January 2018

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Redox regulates mammalian target of rapamycin complex 1 (mTORC1) activity by modulating the TSC1/TSC2-Rheb GTPase pathway

21 January 2018

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Dp44mT targets the AKT, TGF-β and ERK pathways via the metastasis suppressor NDRG1 in normal prostate epithelial cells and prostate cancer cells.

21 January 2018

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Roles of the Ras/Raf/MEK/ERK pathway in leukemia therapy.

21 January 2018

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Homologies between signal transducing G proteins and ras gene products

21 January 2018

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Targeting survival cascades induced by activation of Ras/Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways for effective leukemia therapy.

21 January 2018

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High-throughput sequencing screen reveals novel, transforming RAS mutations in myeloid leukemia patients

21 January 2018

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Blockade of Smad4 in transformed keratinocytes containing a Ras oncogene leads to hyperactivation of the Ras-dependent Erk signalling pathway associated with progression to undifferentiated carcinomas

21 January 2018

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The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation

21 January 2018

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Phosphorylation of Grb2-associated binder 2 on serine 623 by ERK MAPK regulates its association with the phosphatase SHP-2 and decreases STAT5 activation

21 January 2018

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c-Met-Akt pathway-mediated enhancement of inhibitory c-Raf phosphorylation is involved in vitamin K1 and sorafenib synergy on HCC growth inhibition.

21 January 2018

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mTOR: from growth signal integration to cancer, diabetes and ageing

21 January 2018

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Interleukin-18 stimulates fibronectin expression in primary human cardiac fibroblasts via PI3K-Akt-dependent NF-kappaB activation

21 January 2018

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Epithelial-mesenchymal transition: general principles and pathological relevance with special emphasis on the role of matrix metalloproteinases

21 January 2018

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Cortactin is involved in transforming growth factor-beta1-induced epithelial-mesenchymal transition in AML-12 cells

21 January 2018

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Actin stress fibers--assembly, dynamics and biological roles

21 January 2018

1 reference

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The basics of epithelial-mesenchymal transition

21 January 2018

1 reference

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Noncanonical TGF-β signaling during mammary tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGT163

Latency, activation, and binding proteins of TGF-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGT163

TGF-β signalling is mediated by two autonomously functioning TβRI:TβRII pairs

21 January 2018

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Alterations in the Smad pathway in human cancers

21 January 2018

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Smad2 and Smad3 phosphorylated at both linker and COOH-terminal regions transmit malignant TGF-beta signal in later stages of human colorectal cancer.

21 January 2018

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Signaling networks guiding epithelial-mesenchymal transitions during embryogenesis and cancer progression

21 January 2018

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TGF-beta-induced epithelial to mesenchymal transition

21 January 2018

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Modulation of epithelial tight junctions by TGF-beta 3 in cultured oral epithelial cells

21 January 2018

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Non-Smad pathways in TGF-beta signaling

21 January 2018

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In vivo role of lipid adducts on Wingless

21 January 2018

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Wnt/beta-catenin/tcf signaling: a critical pathway in gastrointestinal tumorigenesis

21 January 2018

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Proximal events in Wnt signal transduction

21 January 2018

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Wnt/β-catenin signaling and disease

21 January 2018

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DNAJB6 chaperones PP2A mediated dephosphorylation of GSK3β to downregulate β-catenin transcription target, osteopontin

21 January 2018

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KCl cotransporter-3 down-regulates E-cadherin/beta-catenin complex to promote epithelial-mesenchymal transition

21 January 2018

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Reduced expression of E-cadherin/catenin complex in hepatocellular carcinomas

21 January 2018

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Exploitation of KESTREL to identify NDRG family members as physiological substrates for SGK1 and GSK3

21 January 2018

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Cell Migration: An Overview

21 January 2018

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Actin structure and function.

21 January 2018

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Capping protein and the Arp2/3 complex regulate nonbundle actin filament assembly to indirectly control actin bundle positioning during Drosophila melanogaster bristle development

21 January 2018

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Rho GTPase signaling in Dictyostelium discoideum: insights from the genome

21 January 2018

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A novel role for an APC2-Diaphanous complex in regulating actin organization in Drosophila

21 January 2018

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The WASP-WAVE protein network: connecting the membrane to the cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGT163

Dynamics of capping protein and actin assembly in vitro: uncapping barbed ends by polyphosphoinositides

21 January 2018

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Preparation and characterization of pig plasma and platelet gelsolins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGT163

JunB contributes to Id2 repression and the epithelial-mesenchymal transition in response to transforming growth factor-β.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGT163

Functions of nonmuscle myosin II in assembly of the cellular contractile system

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGT163

Rho-associated kinase-dependent contraction of stress fibres and the organization of focal adhesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGT163

Phosphatidylinositol 3'-kinase signaling pathway is essential for Rac1-induced hypoxia-inducible factor-1(alpha) and vascular endothelial growth factor expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGT163

Signaling through Rho GTPase pathway as viable drug target

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGT163

Role of Rho GTPases and their regulators in cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGT163

Evolution of the Rho family of ras-like GTPases in eukaryotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGT163

Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase)

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGT163

Cdc42/Rac1-dependent activation of the p21-activated kinase (PAK) regulates human platelet lamellipodia spreading: implication of the cortical-actin binding protein cortactin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGT163

Inhibition of Contraction and Myosin Light Chain Phosphorylation in Guinea‐Pig Smooth Muscle by p21‐Activated Kinase 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGT163