(Q35762816)

English

Epithelial-mesenchymal transition: general principles and pathological relevance with special emphasis on the role of matrix metalloproteinases

scientific article published on February 2012

In more languages

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

Epithelial-mesenchymal transition: general principles and pathological relevance with special emphasis on the role of matrix metalloproteinases (English)

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

1

object named as

Paola Nisticò

0 references

2

object named as

Mina J Bissell

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

Derek C Radisky

3

object named as

Derek C Radisky

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

publication date

1 February 2012

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

Cold Spring Harbor Perspectives in Biology

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

The ins and outs of the epithelial to mesenchymal transition in health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281569

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TGFbeta/TNF(alpha)-mediated epithelial-mesenchymal transition generates breast cancer stem cells with a claudin-low phenotype

1 reference

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CD44 splice isoform switching in human and mouse epithelium is essential for epithelial-mesenchymal transition and breast cancer progression

1 reference

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Epithelial-mesenchymal transition (EMT) in kidney fibrosis: fact or fantasy?

1 reference

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Self-organization is a dynamic and lineage-intrinsic property of mammary epithelial cells

1 reference

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TGF-β regulates isoform switching of FGF receptors and epithelial-mesenchymal transition

1 reference

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Metastasis: tumor cells becoming MENAcing

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Snail1 suppresses TGF-beta-induced apoptosis and is sufficient to trigger EMT in hepatocytes

1 reference

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A splicing mastermind for EMT

1 reference

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An ESRP-regulated splicing programme is abrogated during the epithelial-mesenchymal transition

1 reference

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TGF-beta and immune cells: an important regulatory axis in the tumor microenvironment and progression

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Transcriptional crosstalk between TGF-β and stem cell pathways in tumor cell invasion: role of EMT promoting Smad complexes

1 reference

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Snail family regulation and epithelial mesenchymal transitions in breast cancer progression

1 reference

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Matrix metalloproteinase-induced epithelial-mesenchymal transition in breast cancer

1 reference

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2 October 2017

Immune promotion of epithelial-mesenchymal transition and generation of breast cancer stem cells.

1 reference

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Macrophage matrix metalloproteinase-9 mediates epithelial-mesenchymal transition in vitro in murine renal tubular cells

1 reference

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Inflammation and EMT: an alliance towards organ fibrosis and cancer progression

1 reference

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Human mammary progenitor cell fate decisions are products of interactions with combinatorial microenvironments

1 reference

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Epithelial-mesenchymal transition in cancer development and its clinical significance

1 reference

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Epithelial-mesenchymal transitions in development and disease

1 reference

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Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features

1 reference

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Disruption of E-cadherin by matrix metalloproteinase directly mediates epithelial-mesenchymal transition downstream of transforming growth factor-beta1 in renal tubular epithelial cells.

1 reference

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Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease.

1 reference

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Anti-inflammatory and pro-inflammatory roles of TGF-beta, IL-10, and IL-22 in immunity and autoimmunity

1 reference

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Immune-induced epithelial to mesenchymal transition in vivo generates breast cancer stem cells

1 reference

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The epithelial-to-mesenchymal transition and cancer stem cells: a coalition against cancer therapies

1 reference

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Single proteins might have dual but related functions in intracellular and extracellular microenvironments

1 reference

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Mesenchymal cells reactivate Snail1 expression to drive three-dimensional invasion programs

1 reference

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Homology with vesicle fusion mediator syntaxin-1a predicts determinants of epimorphin/syntaxin-2 function in mammary epithelial morphogenesis

1 reference

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Matrix Metalloproteinases as Mediators of Primary and Secondary Cataracts

1 reference

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Generation of breast cancer stem cells through epithelial-mesenchymal transition

1 reference

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Human Mena+11a isoform serves as a marker of epithelial phenotype and sensitivity to epidermal growth factor receptor inhibition in human pancreatic cancer cell lines

1 reference

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TGFbeta in Cancer

1 reference

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Cancer-related inflammation

1 reference

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Matrix metalloproteinase 9 is a mediator of epidermal growth factor-dependent e-cadherin loss in ovarian carcinoma cells

1 reference

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Implications of the cancer stem-cell hypothesis for breast cancer prevention and therapy

1 reference

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Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis

1 reference

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Change in cell shape is required for matrix metalloproteinase-induced epithelial-mesenchymal transition of mammary epithelial cells

1 reference

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2 October 2017

The epithelial-mesenchymal transition generates cells with properties of stem cells

1 reference

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Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways

1 reference

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Membrane type 1 matrix metalloproteinase induces epithelial-to-mesenchymal transition in prostate cancer

1 reference

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Molecular targets in pulmonary fibrosis: the myofibroblast in focus.

1 reference

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Epithelial--mesenchymal and mesenchymal--epithelial transitions in carcinoma progression.

1 reference

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Tumor immunoediting and immunosculpting pathways to cancer progression.

1 reference

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Nuclear factor-kappaB and the hepatic inflammation-fibrosis-cancer axis

1 reference

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2 October 2017

Matrix metalloproteinase-induced epithelial-mesenchymal transition: tumor progression at Snail's pace

1 reference

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Molecular cloning of hMena (ENAH) and its splice variant hMena+11a: epidermal growth factor increases their expression and stimulates hMena+11a phosphorylation in breast cancer cell lines.

1 reference

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2 October 2017

Matrix metalloproteinases and the regulation of tissue remodelling

1 reference

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HER-2/neu antigen loss and relapse of mammary carcinoma are actively induced by T cell-mediated anti-tumor immune responses

1 reference

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Humoral immunity, inflammation and cancer

1 reference

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Catenins: keeping cells from getting their signals crossed

1 reference

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1 reference

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Candidate regulators of mammary branching morphogenesis identified by genome-wide transcript analysis

1 reference

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Hormonal and local control of mammary branching morphogenesis

1 reference

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2 October 2017

Immunoediting of cancers may lead to epithelial to mesenchymal transition.

1 reference

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Pleiotropic effects of FGFR1 on cell proliferation, survival, and migration in a 3D mammary epithelial cell model

1 reference

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Mammographic breast density as an intermediate phenotype for breast cancer

1 reference

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Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability

1 reference

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2 October 2017

The Snail genes as inducers of cell movement and survival: implications in development and cancer.

1 reference

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Regulation of the polarity protein Par6 by TGFbeta receptors controls epithelial cell plasticity

1 reference

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Rac1b, a tumor associated, constitutively active Rac1 splice variant, promotes cellular transformation

1 reference

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The immunobiology of cancer immunosurveillance and immunoediting

1 reference

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2 October 2017

Socializing with the neighbors: stem cells and their niche

1 reference

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2 October 2017

The role of epithelial-to-mesenchymal transition in renal fibrosis

1 reference

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2 October 2017

Mechanisms of pulmonary fibrosis

1 reference

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2 October 2017

Regulation of mammary gland branching morphogenesis by the extracellular matrix and its remodeling enzymes

1 reference

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Alternative splicing of Rac1 generates Rac1b, a self-activating GTPase

1 reference

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2 October 2017

Mechanisms, mechanics and function of epithelial-mesenchymal transitions in early development

1 reference

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Mechanisms of force generation and transmission by myofibroblasts

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Tumor-related alternatively spliced Rac1b is not regulated by Rho-GDP dissociation inhibitors and exhibits selective downstream signaling

1 reference

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2 October 2017

Site-specific inductive and inhibitory activities of MMP-2 and MMP-3 orchestrate mammary gland branching morphogenesis.

1 reference

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2 October 2017

Delivering the message: epimorphin and mammary epithelial morphogenesis

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2 October 2017

Gelatinase A (MMP-2) is necessary and sufficient for renal tubular cell epithelial-mesenchymal transformation

1 reference

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2 October 2017

Stromal effects on mammary gland development and breast cancer

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2 October 2017

Myofibroblasts and mechano-regulation of connective tissue remodelling

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2 October 2017

Matrix Metalloproteinase Inhibitors and Cancer--Trials and Tribulations

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2 October 2017

Putting tumours in context

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2 October 2017

Taking cell-matrix adhesions to the third dimension

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2 October 2017

The mouse snail gene encodes a key regulator of the epithelial-mesenchymal transition

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2 October 2017

How matrix metalloproteinases regulate cell behavior

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2 October 2017

Epimorphin mediates mammary luminal morphogenesis through control of C/EBPbeta

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2 October 2017

Release of an invasion promoter E-cadherin fragment by matrilysin and stromelysin-1.

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2 October 2017

Rac1 in human breast cancer: overexpression, mutation analysis, and characterization of a new isoform, Rac1b

1 reference

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2 October 2017

Mammographic densities and the prevalence and incidence of histological types of benign breast disease. Reference Pathologists of the Canadian National Breast Screening Study

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2 October 2017

The matrix metalloproteinase stromelysin-1 acts as a natural mammary tumor promoter

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2 October 2017

Cloning of a novel human Rac1b splice variant with increased expression in colorectal tumors

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2 October 2017

The stromal proteinase MMP3/stromelysin-1 promotes mammary carcinogenesis

1 reference

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2 October 2017

Epimorphin functions as a key morphoregulator for mammary epithelial cells

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2 October 2017

Matrix metalloproteinase stromelysin-1 triggers a cascade of molecular alterations that leads to stable epithelial-to-mesenchymal conversion and a premalignant phenotype in mammary epithelial cells

1 reference

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2 October 2017

Misregulation of stromelysin-1 expression in mouse mammary tumor cells accompanies acquisition of stromelysin-1-dependent invasive properties

1 reference

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2 October 2017

Targeted expression of stromelysin-1 in mammary gland provides evidence for a role of proteinases in branching morphogenesis and the requirement for an intact basement membrane for tissue-specific gene expression

1 reference

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2 October 2017

A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

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2 October 2017

Mammary gland tumor formation in transgenic mice overexpressing stromelysin-1.

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2 October 2017

The association of histological and radiological indicators of breast cancer risk

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Evaluation of the cocarcinogenic effect of wounding in Rous sarcoma virus tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281569

12 July 2018

Mediation of wound-related Rous sarcoma virus tumorigenesis by TGF-beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281569

12 July 2018

Epilysin (MMP-28) induces TGF-beta mediated epithelial to mesenchymal transition in lung carcinoma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281569

25 September 2018

Matrix metalloproteinase 2 and basement membrane integrity: a unifying mechanism for progressive renal injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281569

25 September 2018

Retinoic acid signaling is required for proper morphogenesis of mammary gland

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281569

25 September 2018

Selected prognostic variables for mammographic parenchymal patterns

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281569

25 September 2018

Myofibroblastic stromal reaction in carcinoma of the breast: variations of collagenous matrix and structural glycoproteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/22300978

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship between mammographic and histologic features of breast tissue in women with benign biopsies

1 reference

https://pubmed.ncbi.nlm.nih.gov/22300978

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epithelial to mesenchymal transition in injury of solid organs: fact or artifact?

1 reference

https://pubmed.ncbi.nlm.nih.gov/22300978

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epithelial-to-mesenchymal transition in liver fibrosis: dead or alive?

1 reference

https://pubmed.ncbi.nlm.nih.gov/22300978

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Radiographic microcalcification and parenchymal patterns as indicators of histologic "high-risk" benign breast disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/22300978

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Smooth-muscle differentiation in stromal cells of malignant and non-malignant breast tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/22300978

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resolved: EMT produces fibroblasts in the kidney

1 reference

https://pubmed.ncbi.nlm.nih.gov/22300978

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlative studies of the histological and radiographic appearance of the breast parenchyma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22300978

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epithelial-mesenchymal transition

1 reference

https://pubmed.ncbi.nlm.nih.gov/22300978

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1101/CSHPERSPECT.A011908

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

ResearchGate publication ID

0 references

Sitelinks

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