(Q38334837)

2 September 2017

Rac1b, a tumor associated, constitutively active Rac1 splice variant, promotes cellular transformation (English)

1 reference

2 September 2017

Anurag Singh

1

0 references

John Sondek

object named as

John Sondek

5

0 references

Ernst Lengyel

object named as

Ernst Lengyel

4

0 references

author name string

Antoine E Karnoub

2

1 reference

2 September 2017

Todd R Palmby

3

1 reference

2 September 2017

Channing J Der

6

1 reference

2 September 2017

language of work or name

English

0 references

publication date

1 December 2004

1 reference

2 September 2017

1 reference

2 September 2017

23

1 reference

2 September 2017

9369-9380

1 reference

2 September 2017

58

1 reference

https://scigraph.springernature.com/pub.10.1038/sj.onc.1208182

2 September 2017

0 references

cites work

Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

Ras and Rho GTPases: a family reunion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

Rho GTPases and their effector proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

The role of Rho GTPases in disease development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

Critical but distinct roles for the pleckstrin homology and cysteine-rich domains as positive modulators of Vav2 signaling and transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

p120 GAP modulates Ras activation of Jun kinases and transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

Rac1 protects epithelial cells against anoikis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

Tiam1 mutations in human renal-cell carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

Rho GTPases in cell biology

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

Alternative splicing of Rac1 generates Rac1b, a self-activating GTPase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

Oncogenic Neu/ErbB-2 increases ets, AP-1, and NF-kappaB-dependent gene expression, and inhibiting ets activation blocks Neu-mediated cellular transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

Crystal structure of the Rac1-RhoGDI complex involved in nadph oxidase activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

Crystal structure of human RhoA in a dominantly active form complexed with a GTP analogue

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

Rho GTPases in transformation and metastasis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

Cloning of a novel human Rac1b splice variant with increased expression in colorectal tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

Integration of Rac-dependent regulation of cyclin D1 transcription through a nuclear factor-kappaB-dependent pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

Molecular basis for Rac1 recognition by guanine nucleotide exchange factors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

Established and emerging fluorescence-based assays for G-protein function: heterotrimeric G-protein alpha subunits and regulator of G-protein signaling (RGS) proteins.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

Tiam1 mediates Ras activation of Rac by a PI(3)K-independent mechanism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

Specific contributions of the small GTPases Rho, Rac, and Cdc42 to Dbl transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

Mice deficient in the Rac activator Tiam1 are resistant to Ras-induced skin tumours.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

Differential localization of Rho GTPases in live cells: regulation by hypervariable regions and RhoGDI binding

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

Rho GTPase-activating proteins in cell regulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

An essential role for Rac in Ras transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

Rho family proteins: coordinating cell responses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

The small GTPases Cdc42Hs, Rac1 and RhoG delineate Raf-independent pathways that cooperate to transform NIH3T3 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

Activation of ERK, controlled by Rac1 and Cdc42 via Akt, is required for anoikis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

RHO-GTPases and cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

Rac1 in human breast cancer: overexpression, mutation analysis, and characterization of a new isoform, Rac1b

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

The relationship of BRMS1 and RhoGDI2 gene expression to metastatic potential in lineage related human bladder cancer cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

rac1 regulates a cytokine-stimulated, redox-dependent pathway necessary for NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

A new rac target POSH is an SH3-containing scaffold protein involved in the JNK and NF-kappaB signalling pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

Cooperative transformation of NIH3T3 cells by G alpha12 and Rac1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

Rho GTPases and signaling networks

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

Role of Rho family GTPases in epithelial morphogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

The guanine nucleotide-binding switch in three dimensions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

RhoG signals in parallel with Rac1 and Cdc42

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

Guanine nucleotide binding properties of Rac2 mutant proteins and analysis of the responsiveness to guanine nucleotide dissociation stimulator

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208182

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1208182

1 reference

Dimensions Publication ID

2 September 2017

0 references

1 reference