(Q38107395)

29 August 2017

title

Protein kinases of Toxoplasma gondii: functions and drug targets (English)

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29 August 2017

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Feng Wei

1

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29 August 2017

Wei Wang

series ordinal

2

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29 August 2017

Quan Liu

series ordinal

3

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29 August 2017

publication date

17 May 2013

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29 August 2017

published in

Parasitology Research

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29 August 2017

volume

112

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29 August 2017

issue

6

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29 August 2017

page(s)

2121-2129

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Virulence differences in Toxoplasma mediated by amplification of a family of polymorphic pseudokinases

29 August 2017

cites work

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Identification of a novel mitogen-activated protein kinase in Toxoplasma gondii.

21 January 2018

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Toxoplasma gondii rhoptry kinase ROP16 activates STAT3 and STAT6 resulting in cytokine inhibition and arginase-1-dependent growth control

21 January 2018

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The Toxoplasma gondii rhoptry protein ROP4 is secreted into the parasitophorous vacuole and becomes phosphorylated in infected cells.

21 January 2018

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Role of mitogen-activated protein kinase kinase kinases in signal integration

21 January 2018

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An inside job: hacking into Janus kinase/signal transducer and activator of transcription signaling cascades by the intracellular protozoan Toxoplasma gondii

21 January 2018

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Toxoplasma gondii cyclic GMP-dependent kinase: chemotherapeutic targeting of an essential parasite protein kinase

21 January 2018

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Molecular characterization of a coccidian parasite cGMP dependent protein kinase

21 January 2018

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Characterization of two T. gondii CK1 isoforms

21 January 2018

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Anticoccidial kinase inhibitors: identification of protein kinase targets secondary to cGMP-dependent protein kinase

21 January 2018

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The ROP2 family of Toxoplasma gondii rhoptry proteins: proteomic and genomic characterization and molecular modeling

21 January 2018

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ROP18 is a rhoptry kinase controlling the intracellular proliferation of Toxoplasma gondii

21 January 2018

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The secreted kinase ROP18 defends Toxoplasma's border

21 January 2018

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The arginine-rich N-terminal domain of ROP18 is necessary for vacuole targeting and virulence of Toxoplasma gondii

21 January 2018

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A Toxoplasma gondii pseudokinase inhibits host IRG resistance proteins

21 January 2018

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Behavioral changes in mice caused by Toxoplasma gondii invasion of brain

21 January 2018

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Characterization, biosynthesis and fate of ROP7, a ROP2 related rhoptry protein of Toxoplasma gondii

21 January 2018

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Plants, symbiosis and parasites: a calcium signalling connection

21 January 2018

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Immunopathogenesis of toxoplasmosis

21 January 2018

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Toxoplasma gondii: transmission, diagnosis and prevention

21 January 2018

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Biology and epidemiology of Toxoplasma gondii in man and animals

21 January 2018

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Molecular cloning and characterization of mitogen-activated protein kinase 2 in Toxoplasma gondii

21 January 2018

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Development of Toxoplasma gondii calcium-dependent protein kinase 1 (TgCDPK1) inhibitors with potent anti-toxoplasma activity

21 January 2018

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Toxoplasma gondii attachment to host cells is regulated by a calmodulin-like domain protein kinase

21 January 2018

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Intracellular targets of cyclin-dependent kinase inhibitors: identification by affinity chromatography using immobilised inhibitors.

21 January 2018

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Identification of Toxoplasma gondii cAMP dependent protein kinase and its role in the tachyzoite growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3451-Y

ROP2 from Toxoplasma gondii: a virulence factor with a protein-kinase fold and no enzymatic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3451-Y

Toxoplasma gondii expresses two mitogen-activated protein kinase genes that represent distinct protozoan subfamilies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3451-Y

Multiple Determinants for Selective Inhibition of Apicomplexan Calcium-Dependent Protein Kinase CDPK1

21 January 2018

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Seroprevalence of Toxoplasma gondii infection in female sterility patients in China.

21 January 2018

1 reference

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rROP2(186-533): a novel peptide antigen for detection of IgM antibodies against Toxoplasma gondii

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3451-Y

Calcium-dependent protein kinase 1 is an essential regulator of exocytosis in Toxoplasma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3451-Y

The protein kinase complement of the human genome

21 January 2018

1 reference

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TgSUB2 is a Toxoplasma gondii rhoptry organelle processing proteinase

21 January 2018

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21 January 2018

1 reference

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Calcium storage and function in apicomplexan parasites

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00436-013-3451-Y

Evaluation of a cyclic GMP-dependent protein kinase inhibitor in treatment of murine toxoplasmosis: gamma interferon is required for efficacy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3451-Y

21 January 2018

Cerebral Toxoplasmosis

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3451-Y

AP-1 in Toxoplasma gondii mediates biogenesis of the rhoptry secretory organelle from a post-Golgi compartment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3451-Y

The rhoptry proteins ROP18 and ROP5 mediate Toxoplasma gondii evasion of the murine, but not the human, interferon-gamma response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3451-Y

Toxoplasma gondii calcium-dependent protein kinase 1 is a target for selective kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3451-Y

Toxoplasma rhoptry protein 16 (ROP16) subverts host function by direct tyrosine phosphorylation of STAT6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3451-Y

Integrative genomic approaches highlight a family of parasite-specific kinases that regulate host responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3451-Y

Seroprevalence of Toxoplasma gondii infection among immigrant and native pregnant women in Eastern Spain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3451-Y

Polymorphic family of injected pseudokinases is paramount in Toxoplasma virulence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3451-Y

Comparative genomics of the apicomplexan parasites Toxoplasma gondii and Neospora caninum: Coccidia differing in host range and transmission strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3451-Y

The Toxoplasma gondii protein ROP2 mediates host organelle association with the parasitophorous vacuole membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3451-Y

1NM-PP1 treatment of mice infected with Toxoplasma gondii.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3451-Y

Use of the kinase inhibitor analog 1NM-PP1 reveals a role for Toxoplasma gondii CDPK1 in the invasion step

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3451-Y

Molecular analyses of Toxoplasma gondii calmodulin-like domain protein kinase isoform 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3451-Y

cAMP-dependent protein kinase: framework for a diverse family of regulatory enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3451-Y

Toxoplasma and coxiella infection and psychiatric morbidity: a retrospective cohort analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3451-Y

A novel Toxoplasma gondii calcium-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3451-Y

Progress in recombinant vaccine development against coccidiosis. A review and prospects into the next millennium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3451-Y

Immune response induced by recombinant Mycobacterium bovis BCG expressing ROP2 gene of Toxoplasma gondii

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3451-Y

Isolation and characterisation of a genomic clone encoding a cdc2-related kinase of Toxoplasma gondii

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3451-Y

Pyridinylimidazole p38 mitogen-activated protein kinase inhibitors block intracellular Toxoplasma gondii replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3451-Y

A role for coccidian cGMP-dependent protein kinase in motility and invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3451-Y

Inhibition of ATF6β-dependent host adaptive immune response by a Toxoplasma virulence factor ROP18.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3451-Y

A single polymorphic amino acid on Toxoplasma gondii kinase ROP16 determines the direct and strain-specific activation of Stat3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3451-Y

ATF6beta is a host cellular target of the Toxoplasma gondii virulence factor ROP18.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3451-Y

Initial characterization of CST1, a Toxoplasma gondii cyst wall glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3451-Y

Benzoylbenzimidazole-based selective inhibitors targeting Cryptosporidium parvum and Toxoplasma gondii calcium-dependent protein kinase-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00436-013-3451-Y

The timing of sulfadiazine therapy impacts the reactivation of latent Toxoplasma infection in IRF-8-/- mice

21 January 2018

1 reference

12 December 2020

Epitopes recognized by human T lymphocytes in the ROP2 protein antigen of Toxoplasma gondii.

1 reference

12 December 2020

Biochemical characterization of mitogen-activated protein (MAP) kinase activity in Toxoplasma gondii

1 reference

12 December 2020

Inverted topology of the Toxoplasma gondii ROP5 rhoptry protein provides new insights into the association of the ROP2 protein family with the parasitophorous vacuole membrane

1 reference

12 December 2020

Protein kinases 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification

1 reference

12 December 2020

Antibody responses to Toxoplasma gondii in sera, intestinal secretions, and milk from orally infected mice and characterization of target antigens

1 reference

12 December 2020

Cyclin-dependent kinase TPK2 is a critical cell cycle regulator in Toxoplasma gondii

1 reference

12 December 2020

Quadruple therapy for ocular toxoplasmosis

1 reference

12 December 2020

Toxoplasma gondii antibodies in cancer patients

1 reference

12 December 2020

Pleiotropic effect due to targeted depletion of secretory rhoptry protein ROP2 in Toxoplasma gondii

1 reference

12 December 2020

Casein kinase I: spatial organization and positioning of a multifunctional protein kinase family

1 reference

12 December 2020

Cyclin-dependent kinases inhibitors as potential anticancer, antineurodegenerative, antiviral and antiparasitic agents

1 reference

12 December 2020

Human T cell clone identifies a potentially protective 54-kDa protein antigen of Toxoplasma gondii cloned and expressed in Escherichia coli

1 reference

12 December 2020

10.1007/S00436-013-3451-Y

Identifiers

DOI

1 reference

Dimensions Publication ID

29 August 2017

1014505717

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1 reference