(Q38108353)

29 August 2017

title

Immune checkpoint blockade immunotherapy to activate anti-tumour T-cell immunity (English)

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29 August 2017

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Alan G Ramsay

1

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29 August 2017

language of work or name

English

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publication date

21 May 2013

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British Journal of Haematology

29 August 2017

published in

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29 August 2017

volume

162

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29 August 2017

issue

3

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29 August 2017

page(s)

313-325

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Programmed death ligand 1 is expressed by non-hodgkin lymphomas and inhibits the activity of tumor-associated T cells

29 August 2017

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Regulation of arginase I activity and expression by both PD-1 and CTLA-4 on the myeloid-derived suppressor cells

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Lenalidomide enhances anti-myeloma cellular immunity

21 January 2018

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Protein kinase c-β-dependent activation of NF-κB in stromal cells is indispensable for the survival of chronic lymphocytic leukemia B cells in vivo.

21 January 2018

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Oncogenic kinase NPM/ALK induces through STAT3 expression of immunosuppressive protein CD274 (PD-L1, B7-H1).

21 January 2018

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Cancer immunotherapy comes of age

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Programmed death 1 signaling on chronic myeloid leukemia-specific T cells results in T-cell exhaustion and disease progression

21 January 2018

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High PD-1 expression and suppressed cytokine signaling distinguish T cells infiltrating follicular lymphoma tumors from peripheral T cells.

21 January 2018

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Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor

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Immunotherapy earns its spot in the ranks of cancer therapy

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Loss of tumor suppressor PTEN function increases B7-H1 expression and immunoresistance in glioma

21 January 2018

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Putting the brakes on BTLA in T cell-mediated cancer immunotherapy

21 January 2018

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Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti-CTLA-4 antibodies

21 January 2018

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BCR-ABL kinase is dead; long live the CML stem cell

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Blockade of programmed death ligand 1 enhances the therapeutic efficacy of combination immunotherapy against melanoma

21 January 2018

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Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia

21 January 2018

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Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4

21 January 2018

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Follicular lymphoma cells induce T-cell immunologic synapse dysfunction that can be repaired with lenalidomide: implications for the tumor microenvironment and immunotherapy

21 January 2018

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Multiple inhibitory ligands induce impaired T-cell immunologic synapse function in chronic lymphocytic leukemia that can be blocked with lenalidomide: establishing a reversible immune evasion mechanism in human cancer

21 January 2018

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Chronic lymphocytic leukemia cells induce defective LFA-1-directed T-cell motility by altering Rho GTPase signaling that is reversible with lenalidomide

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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T cells from CLL patients exhibit features of T-cell exhaustion but retain capacity for cytokine production.

21 January 2018

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21 January 2018

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21 January 2018

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CD28 and CTLA-4 coreceptor expression and signal transduction

21 January 2018

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In a model of tumor dormancy, long-term persistent leukemic cells have increased B7-H1 and B7.1 expression and resist CTL-mediated lysis.

21 January 2018

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Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion

21 January 2018

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Cytotoxic T cells induce proliferation of chronic myeloid leukemia stem cells by secreting interferon-γ.

21 January 2018

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B and T lymphocyte attenuator regulates T cell activation through interaction with herpesvirus entry mediator

21 January 2018

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Long-term repair of T-cell synapse activity in a phase II trial of chemoimmunotherapy followed by lenalidomide consolidation in previously untreated chronic lymphocytic leukemia (CLL).

21 January 2018

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21 January 2018

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Colocalization of inflammatory response with B7-h1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape

21 January 2018

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Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

21 January 2018

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21 January 2018

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21 January 2018

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Cutting edge: cell-extrinsic immune regulation by CTLA-4 expressed on conventional T cells

21 January 2018

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BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1

21 January 2018

1 reference

21 January 2018

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B7-H1 (PD-L1, CD274) suppresses host immunity in T-cell lymphoproliferative disorders.

21 January 2018

1 reference

The B7 homologues and their receptors in hematologic malignancies.

21 January 2018

1 reference

Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors.

21 January 2018

1 reference

The role of CD200 in immunity to B cell lymphoma

21 January 2018

1 reference

Immune inhibitory molecules LAG-3 and PD-1 synergistically regulate T-cell function to promote tumoral immune escape

21 January 2018

1 reference

PD-1-PD-1 ligand interaction contributes to immunosuppressive microenvironment of Hodgkin lymphoma.

21 January 2018

1 reference

Fine tuning the immune response through B7-H3 and B7-H4

21 January 2018

1 reference

Programmed cell death 1 forms negative costimulatory microclusters that directly inhibit T cell receptor signaling by recruiting phosphatase SHP2.

21 January 2018

1 reference

PD-1/PD-L1 interactions inhibit antitumor immune responses in a murine acute myeloid leukemia model

21 January 2018

1 reference

Program death-1 signaling and regulatory T cells collaborate to resist the function of adoptively transferred cytotoxic T lymphocytes in advanced acute myeloid leukemia.

21 January 2018

1 reference

Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia

21 January 2018

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Inhibitory B7-family molecules in the tumour microenvironment

21 January 2018

1 reference

A pilot study of CTLA-4 blockade after cancer vaccine failure in patients with advanced malignancy

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/BJH.12380

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29 August 2017

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