(Q38109390)

29 August 2017

Targeting the viral Achilles' heel: recognition of 5'-triphosphate RNA in innate anti-viral defence (English)

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29 August 2017

2

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29 August 2017

1

Jan Rehwinkel

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29 August 2017

23 May 2013

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Current Opinion in Microbiology

29 August 2017

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29 August 2017

16

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29 August 2017

4

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29 August 2017

485-492

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A diverse range of gene products are effectors of the type I interferon antiviral response

29 August 2017

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12 December 2020

Crystal structure of RIG-I C-terminal domain bound to blunt-ended double-strand RNA without 5' triphosphate

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12 December 2020

Interferons, interferon-like cytokines, and their receptors

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12 December 2020

2'-O methylation of the viral mRNA cap evades host restriction by IFIT family members

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12 December 2020

2'-O methylation of the viral mRNA cap by West Nile virus evades ifit1-dependent and -independent mechanisms of host restriction in vivo

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12 December 2020

Nonself RNA-sensing mechanism of RIG-I helicase and activation of antiviral immune responses

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12 December 2020

Molecular mechanism of signal perception and integration by the innate immune sensor retinoic acid-inducible gene-I (RIG-I).

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12 December 2020

Processing of Genome 5′ Termini as a Strategy of Negative-Strand RNA Viruses to Avoid RIG-I-Dependent Interferon Induction

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12 December 2020

Structural insights into the activation of RIG-I, a nanosensor for viral RNAs

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12 December 2020

Structural basis for viral 5'-PPP-RNA recognition by human IFIT proteins

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12 December 2020

Structural basis of double-stranded RNA recognition by the RIG-I like receptor MDA5

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12 December 2020

RIGorous detection: exposing virus through RNA sensing.

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12 December 2020

TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity

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12 December 2020

tRNA binding, structure, and localization of the human interferon-induced protein IFIT5

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12 December 2020

Structural Insights into RNA Recognition by RIG-I

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12 December 2020

Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5

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12 December 2020

Structure and Dynamics of the Second CARD of Human RIG-I Provide Mechanistic Insights into Regulation of RIG-I Activation

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12 December 2020

A structural basis for discriminating between self and nonself double-stranded RNAs in mammalian cells.

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12 December 2020

IFIT1 is an antiviral protein that recognizes 5'-triphosphate RNA

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12 December 2020

Viral tricks to grid-lock the type I interferon system

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12 December 2020

Defining the subcellular sites of innate immune signal transduction

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12 December 2020

Ubiquitin-induced oligomerization of the RNA sensors RIG-I and MDA5 activates antiviral innate immune response

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12 December 2020

The RIG-I ATPase domain structure reveals insights into ATP-dependent antiviral signalling

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12 December 2020

Incoming RNA virus nucleocapsids containing a 5'-triphosphorylated genome activate RIG-I and antiviral signaling

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12 December 2020

Ribose 2'-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5.

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12 December 2020

Mitochondrial antiviral signaling protein (MAVS) monitors commensal bacteria and induces an immune response that prevents experimental colitis

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12 December 2020

RIG-I detects viral genomic RNA during negative-strand RNA virus infection

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12 December 2020

The Structural Basis of 5′ Triphosphate Double-Stranded RNA Recognition by RIG-I C-Terminal Domain

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12 December 2020

Peroxisomes are signaling platforms for antiviral innate immunity

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12 December 2020

Crystal structure of ISG54 reveals a novel RNA binding structure and potential functional mechanisms

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12 December 2020

Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity

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12 December 2020

Visualizing the Determinants of Viral RNA Recognition by Innate Immune Sensor RIG-I

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12 December 2020

RIG-I detects infection with live Listeria by sensing secreted bacterial nucleic acids

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12 December 2020

Structural basis for dsRNA recognition, filament formation, and antiviral signal activation by MDA5

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12 December 2020

Solution structures of cytosolic RNA sensor MDA5 and LGP2 C-terminal domains: identification of the RNA recognition loop in RIG-I-like receptors

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12 December 2020

ISG56/IFIT1 is primarily responsible for interferon-induced changes to patterns of parainfluenza virus type 5 transcription and protein synthesis

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12 December 2020

Structural basis of RNA recognition and activation by innate immune receptor RIG-I

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12 December 2020

A structure-based model of RIG-I activation

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12 December 2020

Mitochondrial-associated endoplasmic reticulum membranes (MAM) form innate immune synapses and are targeted by hepatitis C virus

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12 December 2020

The C-terminal regulatory domain is the RNA 5'-triphosphate sensor of RIG-I

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12 December 2020

Interferon-induced Ifit2/ISG54 protects mice from lethal VSV neuropathogenesis

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12 December 2020

The ISG56/IFIT1 gene family

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12 December 2020

Exposing viruses: RNA patterns sensed by RIG-I-like receptors

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12 December 2020

Innate recognition of viruses

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12 December 2020

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

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12 December 2020

Type I interferonopathies: a novel set of inborn errors of immunity

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12 December 2020

Structural and functional insights into 5′-ppp RNA pattern recognition by the innate immune receptor RIG-I

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12 December 2020

Structural basis for the activation of innate immune pattern-recognition receptor RIG-I by viral RNA

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12 December 2020

The broad-spectrum antiviral functions of IFIT and IFITM proteins

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12 December 2020

Preference of RIG-I for short viral RNA molecules in infected cells revealed by next-generation sequencing

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12 December 2020

Virus interference. I. The interferon

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12 December 2020

MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response

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12 December 2020

The chase for the RIG-I ligand--recent advances

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12 December 2020

10.1016/J.MIB.2013.04.009

Identifiers

DOI

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29 August 2017

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PubMed ID

23707340