(Q38110734)

29 August 2017

title

Keratin 17: a critical player in the pathogenesis of psoriasis (English)

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29 August 2017

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Liang Jin

1

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29 August 2017

Gang Wang

series ordinal

2

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29 August 2017

publication date

30 May 2013

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Medicinal Research Reviews

29 August 2017

published in

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29 August 2017

volume

34

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29 August 2017

issue

2

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29 August 2017

page(s)

438-454

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Contrasting pathogenesis of atopic dermatitis and psoriasis--part I: clinical and pathologic concepts

29 August 2017

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Psoriasis--epidemiology and clinical spectrum

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Psoriasis genetics: breaking the barrier

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Contrasting pathogenesis of atopic dermatitis and psoriasis--part II: immune cell subsets and therapeutic concepts

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HLA DR B1*04, *07-restricted epitopes on Keratin 17 for autoreactive T cells in psoriasis

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Keratin function in skin epithelia: a broadening palette with surprising shades

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Onset of keratin 17 expression coincides with the definition of major epithelial lineages during skin development

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Structure and functions of keratin proteins in simple, stratified, keratinized and cornified epithelia

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A novel mouse type I intermediate filament gene, keratin 17n (K17n), exhibits preferred expression in nail tissue

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Keratin 16 and keratin 17 mutations cause pachyonychia congenita

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Keratin 17 modulates hair follicle cycling in a TNFalpha-dependent fashion

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A keratin cytoskeletal protein regulates protein synthesis and epithelial cell growth

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Keratin 17 promotes epithelial proliferation and tumor growth by polarizing the immune response in skin

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Type I keratin 17 protein is phosphorylated on serine 44 by p90 ribosomal protein S6 kinase 1 (RSK1) in a growth- and stress-dependent fashion

21 January 2018

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Keratin 17 expression correlates with tumor progression and poor prognosis in gastric adenocarcinoma

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Keratins (Kl6 and Kl7) as markers of keratinocyte hyperproliferation in psoriasis in vivo and in vitro

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21 January 2018

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IL-17A upregulates keratin 17 expression in keratinocytes through STAT1- and STAT3-dependent mechanisms

21 January 2018

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The pro-inflammatory cytokine IL-22 up-regulates keratin 17 expression in keratinocytes via STAT3 and ERK1/2

21 January 2018

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Getting under the skin: the immunogenetics of psoriasis

21 January 2018

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Cytokine-based therapy in psoriasis

21 January 2018

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A single intradermal injection of IFN-γ induces an inflammatory state in both non-lesional psoriatic and healthy skin

21 January 2018

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Interferon-gamma regulates expression of a novel keratin class I gene

21 January 2018

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21 January 2018

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Transcriptional activation of psoriasis-associated cytokeratin K17 by interferon-gamma. Analysis of gamma-interferon activation sites.

21 January 2018

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IL-1 beta and IFN-gamma induce the regenerative epidermal phenotype of psoriasis in the transwell skin organ culture system. IFN-gamma up-regulates the expression of keratin 17 and keratinocyte transglutaminase via endogenous IL-1 production

21 January 2018

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Is an epitope on keratin 17 a major target for autoreactive T lymphocytes in psoriasis?

21 January 2018

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Evidence for a streptococcal superantigen-driven process in acute guttate psoriasis.

21 January 2018

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21 January 2018

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Antigen presentation by keratinocytes directs autoimmune skin disease

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21 January 2018

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Inflammatory skin diseases, T cells, and immune surveillance

21 January 2018

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Cathelicidin antimicrobial peptide LL-37 in psoriasis enables keratinocyte reactivity against TLR9 ligands.

21 January 2018

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Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide

21 January 2018

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Self-RNA-antimicrobial peptide complexes activate human dendritic cells through TLR7 and TLR8.

21 January 2018

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Psoriasis is characterized by accumulation of immunostimulatory and Th1/Th17 cell-polarizing myeloid dendritic cells

21 January 2018

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Th1, Th2, Th17 and regulatory T cell pattern in psoriatic patients: modulation of cytokines and gene targets induced by etanercept treatment and correlation with clinical response.

21 January 2018

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Role of IL-17 in psoriasis and psoriatic arthritis

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21 January 2018

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Overrepresentation of IL-17A and IL-22 producing CD8 T cells in lesional skin suggests their involvement in the pathogenesis of psoriasis

21 January 2018

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Circulating Th17, Th22, and Th1 cells are increased in psoriasis

21 January 2018

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IL-17A is essential for cell activation and inflammatory gene circuits in subjects with psoriasis

21 January 2018

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Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis

21 January 2018

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Distinct roles of IL-22 in human psoriasis and inflammatory bowel disease.

21 January 2018

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Cutting edge: IFN-gamma enables APC to promote memory Th17 and abate Th1 cell development.

21 January 2018

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Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β.

21 January 2018

1 reference

The IL-23/Th17 axis in the immunopathogenesis of psoriasis

21 January 2018

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21 January 2018

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Guidelines of care for the management of psoriasis and psoriatic arthritis: Section 5. Guidelines of care for the treatment of psoriasis with phototherapy and photochemotherapy

21 January 2018

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Guidelines of care for the management of psoriasis and psoriatic arthritis: Section 1. Overview of psoriasis and guidelines of care for the treatment of psoriasis with biologics

21 January 2018

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Novel mechanism of steroid action in skin through glucocorticoid receptor monomers.

21 January 2018

1 reference

Endocrine controls of keratin expression

21 January 2018

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Dithranol and dimethylfumarate suppress the interferon-gamma-induced up-regulation of cytokeratin 17 as a putative psoriasis autoantigen in vitro

21 January 2018

1 reference

Inhibition of keratin 17 expression with antisense and RNAi strategies: exploring novel therapy for psoriasis

21 January 2018

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Characterization of nuclear protein binding sites in the promoter of keratin K17 gene

21 January 2018

1 reference

21 January 2018

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Anti–Interleukin-17 Monoclonal Antibody Ixekizumab in Chronic Plaque Psoriasis

21 January 2018

1 reference

Brodalumab, an Anti–Interleukin-17–Receptor Antibody for Psoriasis

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/MED.21291

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29 August 2017

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