(Q38112504)

6 March 2018

title

Understanding the correlation between in vitro and in vivo immunotoxicity tests for nanomedicines (English)

1 reference

6 March 2018

1 reference

Marina A Dobrovolskaia

series ordinal

1

1 reference

6 March 2018

Scott E McNeil

series ordinal

2

1 reference

6 March 2018

language of work or name

English

0 references

publication date

3 June 2013

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6 March 2018

Journal of Controlled Release

published in

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6 March 2018

volume

172

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6 March 2018

issue

2

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6 March 2018

page(s)

456-466

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6 March 2018

Immune system targeting by biodegradable nanoparticles for cancer vaccines

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Cationic PAMAM dendrimers disrupt key platelet functions.

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Nanoparticle hydrophobicity dictates immune response

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Safety assessment of nanomaterials: implications for nanomedicine.

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23 June 2018

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Immunotoxicant screening and prioritization in the twenty-first century

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Nanoparticle size and surface charge determine effects of PAMAM dendrimers on human platelets in vitro

23 June 2018

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Activation of complement by therapeutic liposomes and other lipid excipient-based therapeutic products: prediction and prevention

23 June 2018

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Alternative in vitro assays in nanomaterial toxicology

23 June 2018

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Macrophage scavenger receptor A mediates the uptake of gold colloids by macrophages in vitro

23 June 2018

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Nanoparticles and modulation of immune responses.

23 June 2018

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Progress in understanding adjuvant immunotoxicity mechanisms

23 June 2018

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Immunotoxicity of nanoparticles

23 June 2018

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An increase in mouse tumor growth by an in vivo immunomodulating effect of titanium dioxide nanoparticles

23 June 2018

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Physical-chemical aspects of protein corona: relevance to in vitro and in vivo biological impacts of nanoparticles

23 June 2018

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Considerations when submitting nanotherapeutics to FDA/CDER for regulatory review

23 June 2018

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Variable antibody-dependent activation of complement by functionalized phospholipid nanoparticle surfaces.

23 June 2018

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Safety and immunotoxicity assessment of immunomodulatory monoclonal antibodies

23 June 2018

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Development, validation and applications of the monocyte activation test for pyrogens based on human whole blood.

23 June 2018

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Update on macrophage clearance of inhaled micro- and nanoparticles

23 June 2018

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Nanomaterial standards for efficacy and toxicity assessment

23 June 2018

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Nanoparticles and the immune system

23 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831149

In vitro comparison of O4-benzylfolate modulated, BCNU-induced toxicity in human bone marrow using CFU-GM and tumor cell lines

23 June 2018

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Contact activation of kallikrein-kinin system by superparamagnetic iron oxide nanoparticles in vitro and in vivo

23 June 2018

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Toxicity of antimony trioxide nanoparticles on human hematopoietic progenitor cells and comparison to cell lines

23 June 2018

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Efficacy of simple short-term in vitro assays for predicting the potential of metal oxide nanoparticles to cause pulmonary inflammation

23 June 2018

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Acute toxicity and prothrombotic effects of quantum dots: impact of surface charge

23 June 2018

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Meeting report: moving upstream-evaluating adverse upstream end points for improved risk assessment and decision-making

23 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831149

Immunological properties of engineered nanomaterials

23 June 2018

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Origin and physiological roles of inflammation

23 June 2018

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Method for analysis of nanoparticle hemolytic properties in vitro

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831149

Preparation of chitosan-polyaspartic acid-5-fluorouracil nanoparticles and its anti-carcinoma effect on tumor growth in nude mice

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831149

High sensitivity pyrogen testing in water and dialysis solutions

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831149

Identifying genetic risk factors for serious adverse drug reactions: current progress and challenges

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831149

Cytokines and other immunological biomarkers in children's environmental health studies

23 June 2018

1 reference

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Animal models of complement-mediated hypersensitivity reactions to liposomes and other lipid-based nanoparticles

23 June 2018

1 reference

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Glycoconjugated peptide dendrimers-based nanoparticulate system for the delivery of chloroquine phosphate.

23 June 2018

1 reference

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Investigations on the toxicological profile of functionalized fifth-generation poly (propylene imine) dendrimer

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831149

Drug withdrawals and the lessons within.

23 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831149

Poly(amidoamine) (PAMAM) dendritic nanostructures for controlled site-specific delivery of acidic anti-inflammatory active ingredient

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831149

Principles for characterizing the potential human health effects from exposure to nanomaterials: elements of a screening strategy

23 June 2018

1 reference

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Nanoparticle-induced platelet aggregation and vascular thrombosis

23 June 2018

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Adverse drug event surveillance and drug withdrawals in the United States, 1969-2002: the importance of reporting suspected reactions

23 June 2018

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Non-CpG-containing antisense 2'-methoxyethyl oligonucleotides activate a proinflammatory response independent of Toll-like receptor 9 or myeloid differentiation factor 88.

23 June 2018

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Analyzing prescription drugs as causes of death on death certificates..

23 June 2018

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The accuracy of extended histopathology to detect immunotoxic chemicals

23 June 2018

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Preparation of magnetic polybutylcyanoacrylate nanospheres encapsulated with aclacinomycin A and its effect on gastric tumor

23 June 2018

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A brief history of immunotoxicology and a review of the pharmaceutical guidelines

23 June 2018

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Extended histopathology in immunotoxicity testing: interlaboratory validation studies

23 June 2018

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Use of CFU-GM assay for prediction of human maximum tolerated dose of a new antitumoral drug: Yondelis (ET-743).

23 June 2018

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From clinical to human toxicology: linking animal research and risk assessment in man.

23 June 2018

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Predicting the maximum-tolerated dose of PNU-159548 (4-demethoxy-3'-deamino-3'-aziridinyl-4'-methylsulphonyl-daunorubicin) in humans using CFU-GM clonogenic assays and prospective validation

23 June 2018

1 reference

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Immunomodulating activities of soluble synthetic polymer-bound drugs

23 June 2018

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Capture of stealth nanoparticles by the body's defences.

23 June 2018

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Dendrimers: relationship between structure and biocompatibility in vitro, and preliminary studies on the biodistribution of 125I-labelled polyamidoamine dendrimers in vivo

23 June 2018

1 reference

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Surface-modified biodegradable albumin nano- and microspheres. II: effect of surface charges on in vitro phagocytosis and biodistribution in rats

23 June 2018

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What else can the immune system recognize?

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831149

Predicting hematological toxicity (myelosuppression) of cytotoxic drug therapy from in vitro tests

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831149

Issues with introducing new immunotoxicology methods into the safety assessment of pharmaceuticals

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831149

Risk assessment in immunotoxicology. II. Relationships between immune and host resistance tests

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831149

Cationic PAMAM dendrimers aggressively initiate blood clot formation.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831149

Dendrimer-induced leukocyte procoagulant activity depends on particle size and surface charge

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831149

Size and surface charge significantly influence the toxicity of silica and dendritic nanoparticles.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831149

Treatment of 9L gliosarcoma in rats by ferrociphenol-loaded lipid nanocapsules based on a passive targeting strategy via the EPR effect.

31 August 2018

1 reference

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Thrombin-inhibiting perfluorocarbon nanoparticles provide a novel strategy for the treatment and magnetic resonance imaging of acute thrombosis

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831149

Prevalidation of the rat CFU-GM assay for in vitro toxicology applications.

31 August 2018

1 reference

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Assessment of pyrogenic contaminations with validated human whole-blood assay

31 August 2018

1 reference

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Single-walled carbon nanotubes activate platelets and accelerate thrombus formation in the microcirculation

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831149

Influence of PEG chain on the complement activation suppression and longevity in vivo prolongation of the PCL biomedical nanoparticles.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831149

Evaluation of nanoparticle immunotoxicity.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831149

Glycodendrimeric nanoparticulate carriers of primaquine phosphate for liver targeting

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831149

A predictive model of human myelotoxicity using five camptothecin derivatives and the in vitro colony-forming unit granulocyte/macrophage assay

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831149

Colloidal gold: a novel nanoparticle vector for tumor directed drug delivery

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831149

Pharmacokinetics of a tumor necrosis factor-alpha phosphorothioate 2'-O-(2-methoxyethyl) modified antisense oligonucleotide: comparison across species

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831149

Complement activation following first exposure to pegylated liposomal doxorubicin (Doxil): possible role in hypersensitivity reactions

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831149

Application of the CFU-GM assay to predict acute drug-induced neutropenia: an international blind trial to validate a prediction model for the maximum tolerated dose (MTD) of myelosuppressive xenobiotics

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831149

A PEGylated dendritic nanoparticulate carrier of fluorouracil

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831149

In vitro tests for haematotoxicity: prediction of drug-induced myelosuppression by the CFU-GM assay.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831149

Prevalidation of a model for predicting acute neutropenia by colony forming unit granulocyte/macrophage (CFU-GM) assay.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831149

Whole blood cytokine response as a measure of immunotoxicity.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831149

Pegylated magnetic nanocarriers for doxorubicin delivery: A quantitative determination of stealthiness in vitro and in vivo

31 August 2018

1 reference

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Silver nanoparticles enhance thrombus formation through increased platelet aggregation and procoagulant activity

3 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5831149

Complement activation is responsible for acute toxicities in rhesus monkeys treated with a phosphorothioate oligodeoxynucleotide

3 December 2018

1 reference

12 December 2020

A murine scavenger receptor MARCO recognizes polystyrene nanoparticles

1 reference

12 December 2020

Differential toxicity of camptothecin, topotecan and 9-aminocamptothecin to human, canine, and murine myeloid progenitors (CFU-GM) in vitro

1 reference

12 December 2020

Increased bone marrow toxicity of doxorubicin bound to nanoparticles

1 reference

12 December 2020

Clinical immunotoxicity of therapeutic proteins

1 reference

12 December 2020

In vitro and in vivo complement activation and related anaphylactic effects associated with polyethylenimine and polyethylenimine-graft-poly(ethylene glycol) block copolymers

1 reference

12 December 2020

Qualitative analysis of total complement activation by nanoparticles

1 reference

12 December 2020

Effect of poly(N-vinyl-pyrrolidone)-block-poly(D,L-lactide) as coating agent on the opsonization, phagocytosis, and pharmacokinetics of biodegradable nanoparticles

1 reference

12 December 2020

Prevention of infusion reactions to PEGylated liposomal doxorubicin via tachyphylaxis induction by placebo vesicles: a porcine model

1 reference

12 December 2020

Amorphous nanosilicas induce consumptive coagulopathy after systemic exposure

1 reference

12 December 2020

Liposome-induced complement activation and related cardiopulmonary distress in pigs: factors promoting reactogenicity of Doxil and AmBisome

1 reference

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Validation of the calibrated thrombin generation test (cTGT) as the reference assay to evaluate the procoagulant activity of nanomaterials

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10.1016/J.JCONREL.2013.05.025

Identifiers

DOI

1 reference

6 March 2018

PMC publication ID

5831149

1 reference

6 March 2018

PubMed publication ID

23742883

1 reference

6 March 2018