(Q38121637)

29 August 2017

title

New therapy options for amyotrophic lateral sclerosis (English)

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amyotrophic lateral sclerosis

29 August 2017

main subject

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author

Paul H. Gordon

series ordinal

1

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29 August 2017

3

Vincent Meininger

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29 August 2017

2

Philippe Corcia

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29 August 2017

language of work or name

English

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publication date

16 July 2013

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Expert Opinion on Pharmacotherapy

29 August 2017

published in

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29 August 2017

volume

14

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29 August 2017

issue

14

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29 August 2017

page(s)

1907-1917

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How can we improve clinical trials in amyotrophic lateral sclerosis?

29 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Lost in translation: treatment trials in the SOD1 mouse and in human ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Guidelines for preclinical animal research in ALS/MND: A consensus meeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

MicroRNA-206 delays ALS progression and promotes regeneration of neuromuscular synapses in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Neuromuscular junction destruction during amyotrophic lateral sclerosis: insights from transgenic models

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Nogo provides a molecular marker for diagnosis of amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

The role of Nogo-A in neuroregeneration: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Myelin-associated glycoprotein as a functional ligand for the Nogo-66 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Oligodendrocyte-myelin glycoprotein is a Nogo receptor ligand that inhibits neurite outgrowth

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Molecular dissection of the myelin-associated glycoprotein receptor complex reveals cell type-specific mechanisms for neurite outgrowth inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Nogo-66 receptor antagonist peptide promotes axonal regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Nogo and axon regeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

The neurite outgrowth inhibitor Nogo-A promotes denervation in an amyotrophic lateral sclerosis model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

NOGO is increased and binds to BACE1 in sporadic inclusion-body myositis and in A beta PP-overexpressing cultured human muscle fibers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Targeting the Nogo-A signalling pathway to promote recovery following acute CNS injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Stem cells and the ALS neurologist

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Neuroprotection for amyotrophic lateral sclerosis: role of stem cells, growth factors, and gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Adult neural stem cells in the mammalian central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Neural stem cells LewisX+ CXCR4+ modify disease progression in an amyotrophic lateral sclerosis model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Human neural stem cell grafts ameliorate motor neuron disease in SOD-1 transgenic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Human neural stem cell grafts in the spinal cord of SOD1 transgenic rats: differentiation and structural integration into the segmental motor circuitry

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Lumbar intraspinal injection of neural stem cells in patients with amyotrophic lateral sclerosis: results of a phase I trial in 12 patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

From bone to brain: human skeletal stem cell therapy for stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Dose-dependent efficacy of ALS-human mesenchymal stem cells transplantation into cisterna magna in SOD1-G93A ALS mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Chimerization of astroglial population in the lumbar spinal cord after mesenchymal stem cell transplantation prolongs survival in a rat model of amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Mesenchymal stem cell transplantation in amyotrophic lateral sclerosis: A Phase I clinical trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Safety and immunological effects of mesenchymal stem cell transplantation in patients with multiple sclerosis and amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Cellular transplants in amyotrophic lateral sclerosis patients: an observational study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Directed differentiation and transplantation of human embryonic stem cell-derived motoneurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Human motor neuron progenitor transplantation leads to endogenous neuronal sparing in 3 models of motor neuron loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Directed differentiation of human-induced pluripotent stem cells generates active motor neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Downregulation of VAPB expression in motor neurons derived from induced pluripotent stem cells of ALS8 patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Induced pluripotent stem cells: a new revolution for clinical neurology?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Wild-type bone marrow cells ameliorate the phenotype of SOD1-G93A ALS mice and contribute to CNS, heart and skeletal muscle tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Intra-bone marrow-bone marrow transplantation slows disease progression and prolongs survival in G93A mutant SOD1 transgenic mice, an animal model mouse for amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Comparative effects between bone marrow and mesenchymal stem cell transplantation in GDNF expression and motor function recovery in a motorneuron degenerative mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Treatment of amyotrophic lateral sclerosis patients by autologous bone marrow-derived hematopoietic stem cell transplantation: a 1-year follow-up.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Energy intake and amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Premorbid weight, body mass, and varsity athletics in ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Energy metabolism in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Evidence for defective energy homeostasis in amyotrophic lateral sclerosis: benefit of a high-energy diet in a transgenic mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Caloric restriction transiently improves motor performance but hastens clinical onset of disease in the Cu/Zn-superoxide dismutase mutant G93A mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Physical fitness, but not muscle strength, is a risk factor for death in amyotrophic lateral sclerosis at an early age

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Cardiovascular fitness as a risk factor for amyotrophic lateral sclerosis: indirect evidence from record linkage study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Physical fitness and amyotrophic lateral sclerosis: dangerous liaisons or common genetic pathways?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Hypermetabolism in ALS: correlations with clinical and paraclinical parameters

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Is hyperlipidemia correlated with longer survival in patients with amyotrophic lateral sclerosis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Body mass index, not dyslipidemia, is an independent predictor of survival in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Beneficial vascular risk profile is associated with amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Lower serum lipid levels are related to respiratory impairment in patients with ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Hypolipidemia in patients with amyotrophic lateral sclerosis: a possible gender difference?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Clinical genetics of amyotrophic lateral sclerosis: what do we really know?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Mutations in the profilin 1 gene cause familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Recent advances in the genetics of amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Cognitive and clinical characteristics of patients with amyotrophic lateral sclerosis carrying a C9orf72 repeat expansion: a population-based cohort study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

C9orf72 repeat expansions are a rare genetic cause of parkinsonism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Corticobasal and ataxia syndromes widen the spectrum of C9ORF72 hexanucleotide expansion disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Genetic variation in DPP6 is associated with susceptibility to amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Antisense oligonucleotide therapeutics for inherited neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

An antisense oligonucleotide against SOD1 delivered intrathecally for patients with SOD1 familial amyotrophic lateral sclerosis: a phase 1, randomised, first-in-man study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

SOD1 in cerebral spinal fluid as a pharmacodynamic marker for antisense oligonucleotide therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Amyotrophic lateral sclerosis, physical exercise, trauma and sports: results of a population-based pilot case-control study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

ALS motor phenotype heterogeneity, focality, and spread: deconstructing motor neuron degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Olfactory ensheathing glia injections in Beijing: misleading patients with ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

High metabolic level in patients with familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Abnormal SMN1 gene copy number is a susceptibility factor for amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

Safety, tolerability and pharmacodynamics of a skeletal muscle activator in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14656566.2013.819344

10.1517/14656566.2013.819344

21 January 2018

Identifiers

DOI

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29 August 2017

1 reference