(Q38121787)

29 August 2017

title

Advances in understanding the pathogenesis of primary Sjögren's syndrome (English)

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29 August 2017

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2

Xavier Mariette

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29 August 2017

Gaëtane Nocturne

1

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29 August 2017

language of work or name

English

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publication date

16 July 2013

1 reference

Nature Reviews Rheumatology

29 August 2017

published in

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29 August 2017

volume

9

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29 August 2017

issue

9

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29 August 2017

page(s)

544-556

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Epidemiology of primary Sjögren's syndrome in north-west Greece, 1982-2003.

29 August 2017

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Viruses induce high expression of BAFF by salivary gland epithelial cells through TLR- and type-I IFN-dependent and -independent pathways

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Association of an IRF5 gene functional polymorphism with Sjögren's syndrome

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The CGGGG insertion/deletion polymorphism of theIRF5promoter is a strong risk factor for primary Sjögren's syndrome

31 March 2020

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Additive effects of the major risk alleles of IRF5 and STAT4 in primary Sjögren's syndrome

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STAT4 is a confirmed genetic risk factor for Sjögren's syndrome and could be involved in type 1 interferon pathway signaling.

31 March 2020

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Variant form of STAT4 is associated with primary Sjögren's syndrome

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The critical importance of epigenetics in autoimmunity

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MicroRNA expression profiles as biomarkers of minor salivary gland inflammation and dysfunction in Sjögren's syndrome

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Immune Interferon in the Circulation of Patients with Autoimmune Disease

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Activation of IFN pathways and plasmacytoid dendritic cell recruitment in target organs of primary Sjögren's syndrome

31 March 2020

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Gene expression profiling of minor salivary glands clearly distinguishes primary Sjögren's syndrome patients from healthy control subjects.

31 March 2020

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Peripheral blood gene expression profiling in Sjögren's syndrome

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Epstein-Barr virus (EBV)-encoded small RNA is released from EBV-infected cells and activates signaling from Toll-like receptor 3.

31 March 2020

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Activation of innate immune responses through Toll-like receptor 3 causes a rapid loss of salivary gland function

31 March 2020

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Expression of Toll-like receptors 7, 8, and 9 in primary Sjögren's syndrome.

31 March 2020

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Activation of innate immunity accelerates sialoadenitis in a mouse model for Sjögren's syndrome-like disease

31 March 2020

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Retrovirus in salivary glands from patients with Sjögren's syndrome

31 March 2020

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Primary Sjögren's syndrome: pathophysiological, clinical and therapeutic advances.

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Murine cytomegalovirus induces a Sjögren's syndrome-like disease in C57Bl/6-lpr/lpr mice

31 March 2020

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A failure of TNFAIP3 negative regulation maintains sustained NF-κB activation in Sjögren’s syndrome

31 March 2020

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Defective feedback regulation of NF-kappaB underlies Sjogren's syndrome in mice with mutated kappaB enhancers of the IkappaBalpha promoter

31 March 2020

1 reference

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Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations

31 March 2020

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TNF Deficiency Fails to Protect BAFF Transgenic Mice against Autoimmunity and Reveals a Predisposition to B Cell Lymphoma

31 March 2020

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The level of BLyS (BAFF) correlates with the titre of autoantibodies in human Sjögren's syndrome

31 March 2020

1 reference

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Aberrant expression of BAFF by B lymphocytes infiltrating the salivary glands of patients with primary Sjögren's syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

B-cell activating factor of the tumour necrosis factor family expression in blood monocytes and T cells from patients with primary Sjögren's syndrome.

31 March 2020

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DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

B-cell-activating factor expressions in salivary epithelial cells after dsRNA virus infection depends on RNA-activated protein kinase activation

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Induction of B cell-activating factor by viral infection is a general phenomenon, but the types of viruses and mechanisms depend on cell type

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Prevalence of interferon type I signature in CD14 monocytes of patients with Sjogren's syndrome and association with disease activity and BAFF gene expression

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Human B lymphoma cell line producing B cell growth factor

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Development of autoimmunity in IL-14alpha-transgenic mice

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

IL-14 alpha, the nexus for primary Sjögren's disease in mice and humans

31 March 2020

1 reference

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Increased frequency of cells secreting interleukin-6 and interleukin-10 in peripheral blood of patients with primary Sjögren's syndrome

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Enhanced apoptotic cell clearance capacity and B cell survival factor production by IL-10-activated macrophages: implications for Burkitt's lymphoma.

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Regulatory B cells in autoimmunity: developments and controversies.

31 March 2020

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Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Classification criteria for Sjögren's syndrome: a revised version of the European criteria proposed by the American-European Consensus Group

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Detection of anti-Ro/SSA and anti-La/SSB autoantibody-producing cells in salivary glands from patients with Sjögren's syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Quantitative assessment of antibodies to ribonucleoproteins in primary Sjögren syndrome: correlation with B-cell biomarkers and disease activity

31 March 2020

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Intra- and intermolecular spreading of autoimmunity involving the nuclear self-antigens La (SS-B) and Ro (SS-A).

31 March 2020

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Molecular signature of a public clonotypic autoantibody in primary Sjögren's syndrome: a "forbidden" clone in systemic autoimmunity.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Ectopic expression of the B cell-attracting chemokine BCA-1 (CXCL13) on endothelial cells and within lymphoid follicles contributes to the establishment of germinal center-like structures in Sjögren's syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Inducible tertiary lymphoid structures, autoimmunity, and exocrine dysfunction in a novel model of salivary gland inflammation in C57BL/6 mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Cellular basis of ectopic germinal center formation and autoantibody production in the target organ of patients with Sjögren's syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

The chemokine receptor CXCR5 is pivotal for ectopic mucosa-associated lymphoid tissue neogenesis in chronic Helicobacter pylori-induced inflammation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Selective localization of T helper subsets in labial salivary glands from primary Sjögren's syndrome patients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Follicular helper T cells in systemic lupus erythematosus: a potential therapeutic target

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

The risk of lymphoma development in autoimmune diseases: a meta-analysis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Lymphoma and other malignancies in primary Sjögren's syndrome: a cohort study on cancer incidence and lymphoma predictors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Autoimmune and Chronic Inflammatory Disorders and Risk of Non-Hodgkin Lymphoma by Subtype

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Incidence of cancer in a nationwide population cohort of 7852 patients with primary Sjogren's syndrome in Taiwan

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Risk of non-Hodgkin's lymphoma in primary Sjögren's syndrome: a population-based study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Prognosis and outcome of non-Hodgkin lymphoma in primary Sjögren syndrome.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Clinicopathological factors relating malignant lymphoma with Sjögren's syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Risk, Predictors, and Clinical Characteristics of Lymphoma Development in Primary Sjögren's Syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Mixed monoclonal cryoglobulinemia and monoclonal rheumatoid factor cross-reactive idiotypes as predictive factors for the development of lymphoma in primary Sjögren's syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Malignant lymphoma in primary Sjögren's syndrome: a multicenter, retrospective, clinical study by the European Concerted Action on Sjögren's Syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Salivary gland lymphomas in patients with Sjögren's syndrome may frequently develop from rheumatoid factor B cells

31 March 2020

2 references

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

31 March 2020

12 December 2020

Among B cell non-Hodgkin's lymphomas, MALT lymphomas express a unique antibody repertoire with frequent rheumatoid factor reactivity

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Lymphoid organisation in labial salivary gland biopsies is a possible predictor for the development of malignant lymphoma in primary Sjögren's syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

C-X-C chemokine receptor type 5 gene polymorphisms are associated with non-Hodgkin lymphoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Serum levels of beta2-microglobulin and free light chains of immunoglobulins are associated with systemic disease activity in primary Sjögren's syndrome. Data at enrollment in the prospective ASSESS cohort

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

BLyS upregulation in Sjogren's syndrome associated with lymphoproliferative disorders, higher ESSDAI score and B-cell clonal expansion in the salivary glands.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Lymphomas complicating Sjögren's syndrome and hepatitis C virus infection may share a common pathogenesis: chronic stimulation of rheumatoid factor B cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Sequencing of TNFAIP3 and association of variants with multiple autoimmune diseases.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

A20 inactivation in ocular adnexal MALT lymphoma.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

TNFAIP3/A20 functions as a novel tumor suppressor gene in several subtypes of non-Hodgkin lymphomas

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Frequent inactivation of A20 in B-cell lymphomas

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

The NF-{kappa}B negative regulator TNFAIP3 (A20) is inactivated by somatic mutations and genomic deletions in marginal zone lymphomas.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

HLA and Sjögren's syndrome susceptibility. A meta-analysis of worldwide studies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

A dual role for interferon-gamma in the pathogenesis of Sjogren's syndrome-like autoimmune exocrinopathy in the nonobese diabetic mouse.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Location of immunization and interferon-γ are central to induction of salivary gland dysfunction in Ro60 peptide immunized model of Sjögren's syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

IL-12 overexpression in mice as a model for Sjögren lung disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Interleukin-12 induces salivary gland dysfunction in transgenic mice, providing a new model of Sjögren's syndrome.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Precise probes of type II interferon activity define the origin of interferon signatures in target tissues in rheumatic diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Cutting edge: autoimmune disease risk variant of STAT4 confers increased sensitivity to IFN-alpha in lupus patients in vivo.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Cytokine-driven proliferation and differentiation of human naive, central memory, and effector memory CD4(+) T cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Increased expression of interleukin-7 in labial salivary glands of patients with primary Sjögren's syndrome correlates with increased inflammation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Increased interleukin (IL)-7Rα expression in salivary glands of patients with primary Sjogren's syndrome is restricted to T cells and correlates with IL-7 expression, lymphocyte numbers and activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Clinical efficacy of leflunomide in primary Sjogren's syndrome is associated with regulation of T-cell activity and upregulation of IL-7 receptor α expression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Systemic and local interleukin-17 and linked cytokines associated with Sjögren's syndrome immunopathogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Identification of IL-18 and Th17 cells in salivary glands of patients with Sjögren's syndrome, and amplification of IL-17-mediated secretion of inflammatory cytokines from salivary gland cells by IL-18.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Foxp3+ T-regulatory cells in Sjogren's syndrome: correlation with the grade of the autoimmune lesion and certain adverse prognostic factors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

The numbers of Foxp3 + Treg cells are positively correlated with higher grade of infiltration at the salivary glands in primary Sjogren's syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

CD4 CD25high regulatory T cells are not impaired in patients with primary Sjögren's syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Potential involvement of IL-22 and IL-22-producing cells in the inflamed salivary glands of patients with Sjogren's syndrome.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Expansion of human NK-22 cells with IL-7, IL-2, and IL-1beta reveals intrinsic functional plasticity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Hypothalamic-pituitary-adrenal axis function in Sjögren's syndrome: mechanisms of neuroendocrine and immune system homeostasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Neuroendocrine dysfunction in Sjogren's syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Development of Autoimmune Exocrinopathy Resembling Sjögren's Syndrome in Estrogen-Deficient Mice of Healthy Background

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Expression of the retinoblastoma protein RbAp48 in exocrine glands leads to Sjögren's syndrome-like autoimmune exocrinopathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Functional estrogen receptors alpha and beta are expressed in normal human salivary gland epithelium and apparently mediate immunomodulatory effects

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Sjögren's syndrome: autoimmune epithelitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Genetically programmed development of salivary gland abnormalities in the NOD (nonobese diabetic)-scid mouse in the absence of detectable lymphocytic infiltration: a potential trigger for sialoadenitis of NOD mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Functional expression of a costimulatory B7.2 (CD86) protein on human salivary gland epithelial cells that interacts with the CD28 receptor, but has reduced binding to CTLA4.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Expression of B7 costimulatory molecules by salivary gland epithelial cells in patients with Sjögren's syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

B cell-activating factor of the tumor necrosis factor family (BAFF) is expressed under stimulation by interferon in salivary gland epithelial cells in primary Sjögren's syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Ribonucleoprotein complexes as autoantigens

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Salivary gland epithelial cell exosomes: A source of autoantigenic ribonucleoproteins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Reduction of fatigue in Sjögren syndrome with rituximab: results of a randomised, double-blind, placebo-controlled pilot study.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Effectiveness of rituximab treatment in primary Sjögren's syndrome: a randomized, double-blind, placebo-controlled trial.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Tolerance and efficacy of rituximab and changes in serum B cell biomarkers in patients with systemic complications of primary Sjögren's syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Dendritic cells directly trigger NK cell functions: cross-talk relevant in innate anti-tumor immune responses in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Reciprocal activating interaction between natural killer cells and dendritic cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Natural-killer cells and dendritic cells: "l'union fait la force".

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Low copy number of the Fc-γ receptor 3B gene FCGR3B is a risk factor for primary Sjogren's syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Association between genetic variants in the tumour necrosis factor/lymphotoxin α/lymphotoxin β locus and primary Sjogren's syndrome in Scandinavian samples

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Polymorphisms of the mannose binding lectin gene in patients with Sjögren's syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

IkappaBalpha promoter polymorphisms in patients with primary Sjögren's syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

TAP, HLA-DQB1, and HLA-DRB1 polymorphism in Colombian patients with primary Sjögren's syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Association of EBF1, FAM167A(C8orf13)-BLK and TNFSF4 gene variants with primary Sjögren's syndrome.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

PTPN22 C1858T polymorphism in Colombian patients with autoimmune diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Genetic association between interleukin-10 promoter region polymorphisms and primary Sjögren's syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Increased Risk of Lymphoma in Sicca Syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Elevated incidence of hematologic malignancies in patients with Sjögren's syndrome compared with patients with rheumatoid arthritis (Finland).

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

A longitudinal cohort study of Finnish patients with primary Sjögren's syndrome: clinical, immunological, and epidemiological aspects

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRRHEUM.2013.110

Lymphomas in patients with Sjogren's syndrome are marginal zone B-cell neoplasms, arise in diverse extranodal and nodal sites, and are not associated with viruses

31 March 2020

1 reference

12 December 2020

CC chemokine receptor 5 and interleukin-1 receptor antagonist gene polymorphisms in patients with primary Sjögren's syndrome

1 reference

12 December 2020

Differential risk of non-Hodgkin's lymphoma in Italian patients with primary Sjögren's syndrome.

1 reference

12 December 2020

Hypofunction of the stress axis in Sjögren's syndrome.

1 reference

12 December 2020

Altered frequency of type 1 cytokine secreting cells in the peripheral blood of patients with primary Sjögren's syndrome

1 reference

12 December 2020

Impaired clearance of apoptotic cardiocytes is linked to anti-SSA/Ro and -SSB/La antibodies in the pathogenesis of congenital heart block.

1 reference

12 December 2020

Increased serum levels of interleukin 10 in Sjögren's syndrome; correlation with increased IgG1

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRRHEUM.2013.110

1 reference

Dimensions Publication ID

29 August 2017

1005899350

0 references

1 reference