(Q38123063)

29 August 2017

Androgen receptor (AR) differential roles in hormone-related tumors including prostate, bladder, kidney, lung, breast and liver (English)

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29 August 2017

C Chang

1

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29 August 2017

S O Lee

series ordinal

2

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29 August 2017

S Yeh

series ordinal

3

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29 August 2017

T M Chang

series ordinal

4

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29 August 2017

language of work or name

English

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publication date

22 July 2013

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29 August 2017

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29 August 2017

33

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29 August 2017

25

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29 August 2017

3225-3234

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https://scigraph.springernature.com/pub.10.1038/onc.2013.274

29 August 2017

0 references

cites work

Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells

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Androgen receptor (AR) coregulators: an overview

31 March 2020

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Androgen receptor (AR) coregulators: a diversity of functions converging on and regulating the AR transcriptional complex

31 March 2020

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The roles of androgen receptors and androgen-binding proteins in nongenomic androgen actions

31 March 2020

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Androgens are powerful non-genomic inducers of calcium sensitization in visceral smooth muscle

31 March 2020

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Generation and characterization of androgen receptor knockout (ARKO) mice: an in vivo model for the study of androgen functions in selective tissues

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Differential androgen receptor signals in different cells explain why androgen-deprivation therapy of prostate cancer fails

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Mutation of the androgen receptor causes oncogenic transformation of the prostate

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Conditional expression of the androgen receptor induces oncogenic transformation of the mouse prostate

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Androgen receptor is a tumor suppressor and proliferator in prostate cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Androgen receptor modifications in prostate cancer cells upon long-termandrogen ablation and antiandrogen treatment.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Androgen-insensitive prostate cancer cells transiently respond to castration treatment when growing in an androgen-dependent prostate environment

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Loss of stromal androgen receptor leads to suppressed prostate tumourigenesis via modulation of pro-inflammatory cytokines/chemokines

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Simultaneous haploinsufficiency of Pten and Trp53 tumor suppressor genes accelerates tumorigenesis in a mouse model of prostate cancer.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Androgen hormone action in prostatic carcinogenesis: stromal androgen receptors mediate prostate cancer progression, malignant transformation and metastasis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Steroid hormones stimulate human prostate cancer progression and metastasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Decrease in stromal androgen receptor associates with androgen-independent disease and promotes prostate cancer cell proliferation and invasion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Generation of a prostate epithelial cell-specific Cre transgenic mouse model for tissue-specific gene ablation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Targeting the stromal androgen receptor in primary prostate tumors at earlier stages

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Dissociation of epithelial and neuroendocrine carcinoma lineages in the transgenic adenocarcinoma of mouse prostate model of prostate cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Is the Achilles' heel for prostate cancer therapy a gain of function in androgen receptor signaling?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Stem/progenitor and intermediate cell types and the origin of human prostate cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Subfertile female androgen receptor knockout mice exhibit defects in neuroendocrine signaling, intraovarian function, and uterine development but not uterine function.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Androgen receptor expression of proliferating basal and luminal cells in adult murine ventral prostate

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Increased prostate cell proliferation and loss of cell differentiation in mice lacking prostate epithelial androgen receptor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Highly purified CD44+ prostate cancer cells from xenograft human tumors are enriched in tumorigenic and metastatic progenitor cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

The role of androgen in determining differentiation and regulation of androgen receptor expression in the human prostatic epithelium transient amplifying population

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Demonstration of intermediate cells during human prostate epithelial differentiation in situ and in vitro using triple-staining confocal scanning microscopy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

New therapy targeting differential androgen receptor signaling in prostate cancer stem/progenitor vs. non-stem/progenitor cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Targeting the unique methylation pattern of androgen receptor (AR) promoter in prostate stem/progenitor cells with 5-aza-2'-deoxycytidine (5-AZA) leads to suppressed prostate tumorigenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Inducible gene targeting in mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Notch signaling is required for normal prostatic epithelial cell proliferation and differentiation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Expression of basal cell keratins in human prostate cancer metastases and cell lines

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Intermediate cells in normal and malignant prostate epithelium express c-MET: implications for prostate cancer invasion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

New therapeutic approach to suppress castration-resistant prostate cancer using ASC-J9 via targeting androgen receptor in selective prostate cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

ASC-J9 ameliorates spinal and bulbar muscular atrophy phenotype via degradation of androgen receptor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

31 March 2020

Cancer statistics, 2010

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Unexplained excess risk of bladder cancer in men.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Specific induction of bladder cancer in mice by butyl-(4-hydroxybutyl)-nitrosamine and the effects of hormonal modifications on the sex difference in response

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Co-localization of androgen receptor with estrogen receptor beta in the lower urinary tract of the male rat

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Androgen receptor expression is inversely correlated with pathologic tumor stage in bladder cancer.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Promotion of bladder cancer development and progression by androgen receptor signals.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Androgen receptor signals regulate UDP-glucuronosyltransferases in the urinary bladder: a potential mechanism of androgen-induced bladder carcinogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Decreased tumorigenesis and mortality from bladder cancer in mice lacking urothelial androgen receptor.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Gene deletion in urothelium by specific expression of Cre recombinase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

European guidelines for the diagnosis and management of upper urinary tract urothelial cell carcinomas: 2011 update

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Significant predictive factors for prognosis of primary upper urinary tract cancer after radical nephroureterectomy in Taiwanese patients.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Prognostic factors in urothelial renal pelvis and ureter tumours: a multicentre Rare Cancer Network study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Upper urinary tract transitional cell carcinoma. A 10-year experience

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

The expression and actions of androgen receptor in upper urinary tract urothelial carcinoma (UUTUC) tissues and the primary cultured cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Upper urinary tract urothelial carcinoma: what have we learned in the last 4 years?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Androgen receptor promotes the migration and invasion of upper urinary tract urothelial carcinoma cells through the upregulation of MMP-9 and COX-2.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Androgen receptor decreases the cytotoxic effects of chemotherapeutic drugs in upper urinary tract urothelial carcinoma cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

ABCG2: determining its relevance in clinical drug resistance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Epidemiology and risk factors for kidney cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Global patterns of cancer incidence and mortality rates and trends

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

A and B forms of the androgen receptor are expressed in a variety of human tissues

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Androgen receptor and androgen-dependent gene expression in lung

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Targeting androgen receptor as a new potential therapeutic approach to battle tobacco carcinogens-induced non-small cell lung cancer.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Lung tumor induction in A/J mice by the tobacco smoke carcinogens 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and benzo[a]pyrene: a potentially useful model for evaluation of chemopreventive agents.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Androgen receptor expression predicts breast cancer survival: the role of genetic and epigenetic events

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Androgen receptor as a target for the treatment of hormone receptor-negative breast cancer: an unchartered territory

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Androgen receptor in triple negative breast cancer.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Minireview: The androgen receptor in breast tissues: growth inhibitor, tumor suppressor, oncogene?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Decreased androgen receptor expression is associated with distant metastases in patients with androgen receptor-expressing triple-negative breast carcinoma.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Amplitude modulation of androgen signaling by c-MYC.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Abnormal mammary gland development and growth retardation in female mice and MCF7 breast cancer cells lacking androgen receptor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Androgen resistance in female mice increases susceptibility to DMBA-induced mammary tumors.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Interactions between androgen and estrogen receptors and the effects on their transactivational properties

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Hepatocellular carcinoma: epidemiology and molecular carcinogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Role of sex steroid receptors in pathobiology of hepatocellular carcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Androgen dependency of hepatocarcinogenesis in TGFalpha transgenic mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Hepatocellular carcinoma associated with liver-gender disruption in male mice.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Megestrol acetate in unresectable hepatocellular carcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Randomized trial of leuprorelin and flutamide in male patients with hepatocellular carcinoma treated with tamoxifen

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Updated treatment approach to hepatocellular carcinoma.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Promotion of murine hepatocarcinogenesis by testosterone is androgen receptor-dependent but not cell autonomous

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Androgen activates PEG10 to promote carcinogenesis in hepatic cancer cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Involvement of protein kinase C beta-extracellular signal-regulating kinase 1/2/p38 mitogen-activated protein kinase-heat shock protein 27 activation in hepatocellular carcinoma cell motility and invasion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Cytokine activation of p38 mitogen-activated protein kinase and apoptosis is opposed by alpha-4 targeting of protein phosphatase 2A for site-specific dephosphorylation of MEK3.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Illuminating the metastatic process

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Enhancement of gene transactivation activity of androgen receptor by hepatitis B virus X protein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Hepatitis B virus X protein enhances the transcriptional activity of the androgen receptor through c-Src and glycogen synthase kinase-3beta kinase pathways

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Transgenic mouse models of hepatitis B virus-associated hepatocellular carcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

Sustained activation of mitogen-activated protein kinases and activator protein 1 by the hepatitis B virus X protein in mouse hepatocytes in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.274

31 March 2020

Identifiers

DOI

10.1038/ONC.2013.274

1 reference

Dimensions Publication ID

29 August 2017

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1 reference