(Q40164058)

18 September 2017

ASC-J9 ameliorates spinal and bulbar muscular atrophy phenotype via degradation of androgen receptor (English)

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18 September 2017

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6

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18 September 2017

8

Gen Sobue

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18 September 2017

Zhiming Yang

1

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18 September 2017

Yu-Jia Chang

2

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18 September 2017

I-Chen Yu

3

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18 September 2017

Shuyuan Yeh

4

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18 September 2017

Cheng-Chia Wu

5

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18 September 2017

Diane E Merry

7

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18 September 2017

Lu-Min Chen

9

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18 September 2017

Shu-Shi Chang

10

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18 September 2017

Chawnshang Chang

11

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18 September 2017

language of work or name

English

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publication date

4 March 2007

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18 September 2017

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18 September 2017

13

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18 September 2017

348-353

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18 September 2017

3

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https://scigraph.springernature.com/pub.10.1038/nm1547

18 September 2017

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cites work

Progressive proximal spinal and bulbar muscular atrophy of late onset: a sex-linked recessive trait.

1 reference

7 January 2021

Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy

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7 January 2021

Late-onset X-linked recessive spinal and bulbar muscular atrophy

1 reference

7 January 2021

X-linked recessive bulbospinal neuronopathy. A clinicopathological study

1 reference

7 January 2021

Testosterone reduction prevents phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy

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7 January 2021

Nuclear inclusions of the androgen receptor protein in spinal and bulbar muscular atrophy.

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7 January 2021

Molecular Cloning of Human and Rat Complementary DNA Encoding Androgen Receptors

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7 January 2021

Androgen receptor in prostate cancer

1 reference

7 January 2021

Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells

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7 January 2021

Androgen receptor (AR) coregulators: an overview

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7 January 2021

Polyglutamine and CBP: fatal attraction?

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7 January 2021

Cellular defenses against unfolded proteins: a cell biologist thinks about neurodegenerative diseases

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7 January 2021

Polyglutamine pathogenesis: emergence of unifying mechanisms for Huntington's disease and related disorders

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7 January 2021

Cleavage, aggregation and toxicity of the expanded androgen receptor in spinal and bulbar muscular atrophy

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7 January 2021

Role of proteolysis in polyglutamine disorders

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7 January 2021

Transglutaminase potentiates ligand-dependent proteasome dysfunction induced by polyglutamine-expanded androgen receptor

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7 January 2021

Cytochrome c oxidase subunit Vb interacts with human androgen receptor: a potential mechanism for neurotoxicity in spinobulbar muscular atrophy

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7 January 2021

Polyglutamine diminishes VEGF; passage to motor neuron death?

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7 January 2021

Leuprorelin rescues polyglutamine-dependent phenotypes in a transgenic mouse model of spinal and bulbar muscular atrophy

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7 January 2021

Sodium butyrate ameliorates phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy

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7 January 2021

Castration restores function and neurofilament alterations of aged symptomatic males in a transgenic mouse model of spinal and bulbar muscular atrophy.

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7 January 2021

Antitumor agents. 217. Curcumin analogues as novel androgen receptor antagonists with potential as anti-prostate cancer agents

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7 January 2021

Ligand promotes intranuclear inclusions in a novel cell model of spinal and bulbar muscular atrophy

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7 January 2021

Androgen receptor YAC transgenic mice recapitulate SBMA motor neuronopathy and implicate VEGF164 in the motor neuron degeneration

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7 January 2021

17-AAG, an Hsp90 inhibitor, ameliorates polyglutamine-mediated motor neuron degeneration

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7 January 2021

The Hsp90 chaperone complex as a novel target for cancer therapy

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7 January 2021

Analysis of FKBP51/FKBP52 chimeras and mutants for Hsp90 binding and association with progesterone receptor complexes

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7 January 2021

Progesterone receptor structure and function altered by geldanamycin, an hsp90-binding agent

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7 January 2021

Phase I pharmacokinetic and pharmacodynamic study of 17-allylamino, 17-demethoxygeldanamycin in patients with advanced malignancies

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7 January 2021

The heat shock protein 90 inhibitor, 17-allylamino-17-demethoxygeldanamycin, enhances osteoclast formation and potentiates bone metastasis of a human breast cancer cell line

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7 January 2021

Mutations in the helix 3 region of the androgen receptor abrogate ARA70 promotion of 17beta-estradiol-induced androgen receptor transactivation.

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7 January 2021

Suppression of androgen receptor-mediated transactivation and cell growth by the glycogen synthase kinase 3 beta in prostate cells

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7 January 2021

Polyglutamine-expanded ataxin-7 promotes non-cell-autonomous purkinje cell degeneration and displays proteolytic cleavage in ataxic transgenic mice.

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7 January 2021

Transgenic mice with an expanded CAG repeat controlled by the human AR promoter show polyglutamine nuclear inclusions and neuronal dysfunction without neuronal cell death

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7 January 2021

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7 January 2021

Identifiers

DOI

10.1038/NM1547

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18 September 2017

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