(Q38127840)

29 August 2017

title

Genetic and genomic approaches for the discovery of parasite genes involved in antimalarial drug resistance (English)

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29 August 2017

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1

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Lisa C Ranford-Cartwright

29 August 2017

series ordinal

2

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29 August 2017

publication date

9 August 2013

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29 August 2017

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29 August 2017

volume

140

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29 August 2017

issue

12

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29 August 2017

page(s)

1455-1467

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Genetic mapping of the chloroquine-resistance locus on Plasmodium falciparum chromosome 7.

29 August 2017

cites work

1 reference

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Altered Dihydrofolate Reductase associated with a Pyrimethamine-resistant Plasmodium berghei berghei produced in a Single Step

21 January 2018

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Chloroquine-resistant Plasmodium falciparum isolates from the Sudan lack two mutations in the pfmdr1 gene thought to be associated with chloroquine resistance

21 January 2018

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A simple model of the build-up of resistance to mixtures of anti-malarial drugs.

21 January 2018

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Reversal of chloroquine resistance in Plasmodium falciparum by verapamil

21 January 2018

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pfcrt polymorphism and chloroquine resistance in Plasmodium falciparum strains isolated in Cambodia

21 January 2018

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Assessment of the association between three pfmdr1 point mutations and chloroquine resistance in vitro of Malaysian Plasmodium falciparum isolates.

21 January 2018

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Amino acid changes linked to pyrimethamine resistance in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum

21 January 2018

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Efflux of chloroquine from Plasmodium falciparum: mechanism of chloroquine resistance.

21 January 2018

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Mutations in Plasmodium falciparum cytochrome b that are associated with atovaquone resistance are located at a putative drug-binding site

21 January 2018

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Targeted inhibition of angiogenic factors in AIDS-related disorders

21 January 2018

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Different mutation patterns of atovaquone resistance to Plasmodium falciparum in vitro and in vivo: rapid detection of codon 268 polymorphisms in the cytochrome b as potential in vivo resistance marker

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

Alternative mutations at position 76 of the vacuolar transmembrane protein PfCRT are associated with chloroquine resistance and unique stereospecific quinine and quinidine responses in Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

Plasmodium yoelii: genetic analysis of crosses between two rodent malaria subspecies

21 January 2018

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The epidemiology of multiple-clone Plasmodium falciparum infections in Gambian patients

21 January 2018

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Malaria research. Inbred parasites may spur resistance

21 January 2018

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Studies on the compound 50-63.

21 January 2018

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https://api.crossref.org/works/10.1017%2FS0031182013000954

Ferriprotoporphyrin IX fulfills the criteria for identification as the chloroquine receptor of malaria parasites

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

Evaluation of atovaquone in the treatment of patients with uncomplicated Plasmodium falciparum malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

The emergence of drug-resistant malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

pfcrt Allelic types with two novel amino acid mutations in chloroquine-resistant Plasmodium falciparum isolates from the Philippines

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

Atovaquone and proguanil for Plasmodium falciparum malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

Effects of artemisinin derivatives on malaria transmissibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

Uptake of [3H]chloroquine by drug-sensitive and -resistant strains of the human malaria parasite Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

Amplification of a gene related to mammalian mdr genes in drug-resistant Plasmodium falciparum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

Antimalarial drug resistance: the pace quickens

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

The dynamics of drug resistance in Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

Mutations in Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase and epidemiologic patterns of pyrimethamine-sulfadoxine use and resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

Amino acids in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum involved in cycloguanil resistance differ from those involved in pyrimethamine resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

Epidemiology of drug-resistant malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

Malaria: even more chronic in nature than previously thought; evidence for subpatent parasitaemia detectable by the polymerase chain reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

Evidence that a point mutation in dihydrofolate reductase-thymidylate synthase confers resistance to pyrimethamine in falciparum malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

Chloroquine-resistant Plasmodium falciparum malaria in Kenya

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

Did medicated salt hasten the spread of chloroquine resistance in Plasmodium falciparum?

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

Three hundred and fifty years of the Peruvian fever bark

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

Genetic diversity and chloroquine selective sweeps in Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Increased tolerance to artemisinin in Plasmodium falciparum is mediated by a quiescence mechanism

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Malarone treatment failure not associated with previously described mutations in the cytochrome b gene

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Screening for mutations related to atovaquone/proguanil resistance in treatment failures and other imported isolates of Plasmodium falciparum in Europe

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Chloroquine resistance not linked to mdr-like genes in a Plasmodium falciparum cross

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

In vivo sensitivity monitoring of mefloquine monotherapy and artesunate-mefloquine combinations for the treatment of uncomplicated falciparum malaria in Thailand in 2003.

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Identification and functional validation of the novel antimalarial resistance locus PF10_0355 in Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

The glyoxalase system of malaria parasites--implications for cell biology and general glyoxalase research

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Mutations in the Plasmodium falciparum cytochrome b gene are associated with delayed parasite recrudescence in malaria patients treated with atovaquone-proguanil

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Genetic linkage and association analyses for trait mapping in Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Kinetic and molecular properties of dihydrofolate reductase from pyrimethamine-sensitive and pyrimethamine-resistant Plasmodium chabaudi

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Antifolate antimalarial resistance in southeast Africa: a population-based analysis

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

The pfmdr1 gene is associated with a multidrug-resistant phenotype in Plasmodium falciparum from the western border of Thailand.

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Pfmdr1 Asn1042Asp and Asp1246Tyr polymorphisms, thought to be associated with chloroquine resistance, are present in chloroquine-resistant and -sensitive Brazilian field isolates of Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Prevalence of the dihydrofolate reductase Asn-108 mutation as the basis for pyrimethamine-resistant falciparum malaria in the Brazilian Amazon.

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

The problem of drug resistance in malaria

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

The global portfolio of new antimalarial medicines under development.

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

In vitro activities of quinine and other antimalarials and pfnhe polymorphisms in Plasmodium isolates from Kenya

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Kenyan Plasmodium falciparum field isolates: correlation between pyrimethamine and chlorcycloguanil activity in vitro and point mutations in the dihydrofolate reductase domain.

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Phenotypic and genotypic characteristics of recently adapted isolates of Plasmodium falciparum from Thailand

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Clinical studies of atovaquone, alone or in combination with other antimalarial drugs, for treatment of acute uncomplicated malaria in Thailand

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Point mutations and pyrimethamine resistance in Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Plasmodium falciparum Na+/H+ exchanger 1 transporter is involved in reduced susceptibility to quinine

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

The origins of antimalarial drug resistance

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Accumulation of artemisinin trioxane derivatives within neutral lipids of Plasmodium falciparum malaria parasites is endoperoxide-dependent

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Amplification of the multidrug resistance gene in some chloroquine-resistant isolates of P. falciparum

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Several alleles of the multidrug-resistance gene are closely linked to chloroquine resistance in Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Dissecting the loci of low-level quinine resistance in malaria parasites

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

PLASMODIUM FALCIPARUM RESISTANT TO CHLOROQUINE IN CAMBODIA.

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

An assessment of drug-haematin binding as a mechanism for inhibition of haematin polymerisation by quinoline antimalarials

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Fake antimalarials in Southeast Asia are a major impediment to malaria control: multinational cross-sectional survey on the prevalence of fake antimalarials

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

A molecular marker for chloroquine-resistant falciparum malaria

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

pfcrt is more than the Plasmodium falciparum chloroquine resistance gene: a functional and evolutionary perspective

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

A genetic map and recombination parameters of the human malaria parasite Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Artemisinin-induced parasite dormancy: a plausible mechanism for treatment failure

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

A major genome region underlying artemisinin resistance in malaria

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

In vitro susceptibility to quinine and microsatellite variations of the Plasmodium falciparum Na+/H+ exchanger (Pfnhe-1) gene: the absence of association in clinical isolates from the Republic of Congo

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Access to hematin: the basis of chloroquine resistance.

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Kinetic characterization of Na+/H+ antiport of Plasmodium falciparum membrane

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Selection strength and hitchhiking around two anti-malarial resistance genes.

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Mass treatment with pyrimethamine; a study of resistance and cross resistance resulting from a field trial in the hyperendemic malarious area of Makueni, Kenya. September 1952-September 1953

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

The inhibitory action of naphthoquinones on respiratory process; the inhibition of cleavage and respiration in the eggs of Arbacia punctulata

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

High heritability of malaria parasite clearance rate indicates a genetic basis for artemisinin resistance in western Cambodia

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Plasmodium falciparum: molecular characterization of multidrug-resistant Cambodian isolates

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

The development and spread of drug-resistant malaria

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Resistance mutations reveal the atovaquone-binding domain of cytochrome b in malaria parasites

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Chloroquine-resistant malaria

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Some 7-substituted 4-aminoquinoline derivatives

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Role for the plasmodium falciparum digestive vacuole in chloroquine resistance

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

The origins and spread of antimalarial drug resistance: lessons for policy makers

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Evidence of Artemisinin-Resistant Malaria in Western Cambodia

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Fatal cardiotoxicity related to halofantrine: a review based on a worldwide safety data base

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Chloroquine resistance in Plasmodium falciparum malaria parasites conferred by pfcrt mutations

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Chloroquine-resistant Plasmodium falciparum from East Africa: cultivation and drug sensitivity of the Tanzanian I/CDC strain from an American tourist

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Artemisinin activity against Plasmodium falciparum requires hemoglobin uptake and digestion

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Sustained clinical efficacy of sulfadoxine-pyrimethamine for uncomplicated falciparum malaria in Malawi after 10 years as first line treatment: five year prospective study

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

A genetic investigation of virulence in a rodent malaria parasite

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

New medicines to improve control and contribute to the eradication of malaria

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Artemisinin Resistance in Plasmodium falciparum Malaria

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Analysis of malaria parasite phenotypes using experimental genetic crosses of Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Analysis of pfmdr1 and drug susceptibility in fresh isolates of Plasmodium falciparum from subsaharan Africa

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Trans stimulation provides evidence for a drug efflux carrier as the mechanism of chloroquine resistance in Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Drug resistance-associated pfCRT mutations confer decreased Plasmodium falciparum digestive vacuolar pH.

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Site of action of the antimalarial hydroxynaphthoquinone, 2-[trans-4-(4'-chlorophenyl) cyclohexyl]-3- hydroxy-1,4-naphthoquinone (566C80)

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

The tyrosine-86 allele of the pfmdr1 gene of Plasmodium falciparum is associated with increased sensitivity to the anti-malarials mefloquine and artemisinin

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Complex polymorphisms in an approximately 330 kDa protein are linked to chloroquine-resistant P. falciparum in Southeast Asia and Africa

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

High-level chloroquine resistance in Sudanese isolates of Plasmodium falciparum is associated with mutations in the chloroquine resistance transporter gene pfcrt and the multidrug resistance Gene pfmdr1.

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Molecular assays for surveillance of antifolate-resistant malaria

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

Antimalarial drug resistance

1 reference

https://api.crossref.org/works/10.1017%2FS0031182013000954

7 January 2021

10.1017/S0031182013000954

Identifiers

DOI

1 reference

29 August 2017

1 reference