(Q37615897)

21 August 2017

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title

New medicines to improve control and contribute to the eradication of malaria (English)

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21 August 2017

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Timothy N C Wells

1

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Pedro L. Alonso

series ordinal

2

object named as

Pedro L Alonso

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21 August 2017

Winston E Gutteridge

3

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21 August 2017

16 October 2009

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Nature Reviews Drug Discovery

21 August 2017

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21 August 2017

8

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21 August 2017

879-891

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21 August 2017

11

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https://scigraph.springernature.com/pub.10.1038/nrd2972

21 August 2017

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Plasmodium knowlesi malaria in humans is widely distributed and potentially life threatening

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A systematic review and meta-analysis of the effectiveness and safety of atovaquone proguanil (Malarone) for chemoprophylaxis against malaria

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Selection of a trioxaquine as an antimalarial drug candidate

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Two-step synthesis of achiral dispiro-1,2,4,5-tetraoxanes with outstanding antimalarial activity, low toxicity, and high-stability profiles

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Identification of an antimalarial synthetic trioxolane drug development candidate

31 March 2020

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Assessment of azithromycin in combination with other antimalarial drugs against Plasmodium falciparum in vitro

31 March 2020

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A multicenter study of azithromycin, alone and in combination with chloroquine, for the treatment of acute uncomplicated Plasmodium falciparum malaria in India

31 March 2020

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31 March 2020

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Evidence-based annotation of the malaria parasite's genome using comparative expression profiling

31 March 2020

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Genomic-scale prioritization of drug targets: the TDR Targets database

31 March 2020

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Structural Basis for Selective Inhibition of Mycobacterium tuberculosis Protein Tyrosine Phosphatase PtpB

31 March 2020

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In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen

31 March 2020

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Rationale and plans for developing a non-replicating, metabolically active, radiation-attenuatedPlasmodium falciparumsporozoite vaccine

31 March 2020

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Cultivation of Plasmodium vivax

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31 March 2020

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Synthesis and structure-activity relationships of 4-pyridones as potential antimalarials

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High-throughput screening for potent and selective inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase

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Identification of a metabolically stable triazolopyrimidine-based dihydroorotate dehydrogenase inhibitor with antimalarial activity in mice

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Structures of Substrate- and Inhibitor-Bound Adenosine Deaminase from a Human Malaria Parasite Show a Dramatic Conformational Change and Shed Light on Drug Selectivity

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X-ray structural analysis of Plasmodium falciparum enoyl acyl carrier protein reductase as a pathway toward the optimization of triclosan antimalarial efficacy

31 March 2020

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Protein kinases of malaria parasites: an update

31 March 2020

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Identification and characterization of small molecule inhibitors of a class I histone deacetylase from Plasmodium falciparum

31 March 2020

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Structures of Falcipain-2 and Falcipain-3 Bound to Small Molecule Inhibitors: Implications for Substrate Specificity ‡

31 March 2020

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Subcellular discharge of a serine protease mediates release of invasive malaria parasites from host erythrocytes

31 March 2020

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A class of potent antimalarials and their specific accumulation in infected erythrocytes

31 March 2020

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Pre-referral rectal artesunate to prevent death and disability in severe malaria: a placebo-controlled trial

31 March 2020

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12 December 2020

Artemisinin and the antimalarial endoperoxides: from herbal remedy to targeted chemotherapy.

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12 December 2020

The apicoplast: a review of the derived plastid of apicomplexan parasites.

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12 December 2020

Antimalarial drug resistance and the importance of drug quality monitoring.

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12 December 2020

Editorial: Global Health Fund or Global Fund to fight AIDS, Tuberculosis, and Malaria?

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12 December 2020

A pre-emptive strike against malaria's stealthy hepatic forms

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12 December 2020

Identifiers

DOI

10.1038/NRD2972

1 reference

21 August 2017

1 reference

PubMed ID

19834482