(Q38128200)

29 August 2017

title

Myosin II in mechanotransduction: master and commander of cell migration, morphogenesis, and cancer (English)

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Miguel Vicente-Manzanares

29 August 2017

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1 reference

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object named as

Miguel Vicente-Manzanares

series ordinal

3

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author name string

Rocío Aguilar-Cuenca

series ordinal

1

1 reference

29 August 2017

Alba Juanes-García

series ordinal

2

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29 August 2017

publication date

11 August 2013

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Cellular and Molecular Life Sciences

29 August 2017

published in

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29 August 2017

volume

71

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29 August 2017

issue

3

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29 August 2017

page(s)

479-492

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https://scigraph.springernature.com/pub.10.1007/s00018-013-1439-5

29 August 2017

exact match

0 references

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Rho kinase differentially regulates phosphorylation of nonmuscle myosin II isoforms A and B during cell rounding and migration

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TRPM7 regulates myosin IIA filament stability and protein localization by heavy chain phosphorylation

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Mitosis-specific mechanosensing and contractile-protein redistribution control cell shape

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Actin and alpha-actinin orchestrate the assembly and maturation of nascent adhesions in a myosin II motor-independent manner

21 January 2018

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During multicellular migration, myosin ii serves a structural role independent of its motor function

21 January 2018

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Non-muscle myosin II takes centre stage in cell adhesion and migration

21 January 2018

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Nonmuscle myosin II moves in new directions

21 January 2018

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21 January 2018

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Phosphorylation of platelet myosin increases actin-activated myosin ATPase activity

21 January 2018

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A role for the Rho-p160 Rho coiled-coil kinase axis in the chemokine stromal cell-derived factor-1alpha-induced lymphocyte actomyosin and microtubular organization and chemotaxis

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Disease-associated mutations and alternative splicing alter the enzymatic and motile activity of nonmuscle myosins II-B and II-C

21 January 2018

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Morphogenesis in Drosophila requires nonmuscle myosin heavy chain function.

21 January 2018

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Nonmuscle myosin II generates forces that transmit tension and drive contraction in multiple tissues during dorsal closure

21 January 2018

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Mechanical signals trigger Myosin II redistribution and mesoderm invagination in Drosophila embryos

21 January 2018

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Focal contacts as mechanosensors: externally applied local mechanical force induces growth of focal contacts by an mDia1-dependent and ROCK-independent mechanism

21 January 2018

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21 January 2018

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21 January 2018

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Integrins: bidirectional, allosteric signaling machines

21 January 2018

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Rho-mediated contractility exposes a cryptic site in fibronectin and induces fibronectin matrix assembly.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Rho-stimulated contractility drives the formation of stress fibers and focal adhesions

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Nascent focal adhesions are responsible for the generation of strong propulsive forces in migrating fibroblasts

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Mechanically activated integrin switch controls alpha5beta1 function

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Regulation of integrin affinity on cell surfaces

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Integrin avidity regulation: are changes in affinity and conformation underemphasized?

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Functional atlas of the integrin adhesome

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Interaction of plasma membrane fibronectin receptor with talin--a transmembrane linkage

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Biochemical and structural properties of the integrin-associated cytoskeletal protein talin

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Two-piconewton slip bond between fibronectin and the cytoskeleton depends on talin

21 January 2018

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Stretching single talin rod molecules activates vinculin binding

21 January 2018

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The phosphotyrosine binding-like domain of talin activates integrins

21 January 2018

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Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Visualizing the mechanical activation of Src.

21 January 2018

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Integrin-ligand binding properties govern cell migration speed through cell-substratum adhesiveness

21 January 2018

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Cytoskeletal dynamics and nerve growth

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Probing the integrin-actin linkage using high-resolution protein velocity mapping

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Differential transmission of actin motion within focal adhesions

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Slipping or gripping? Fluorescent speckle microscopy in fish keratocytes reveals two different mechanisms for generating a retrograde flow of actin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Traction stress in focal adhesions correlates biphasically with actin retrograde flow speed

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Localized zones of Rho and Rac activities drive initiation and expansion of epithelial cell-cell adhesion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Myosin 2 is a key Rho kinase target necessary for the local concentration of E-cadherin at cell-cell contacts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Defects in cell adhesion and the visceral endoderm following ablation of nonmuscle myosin heavy chain II-A in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Myosin II dynamics are regulated by tension in intercalating cells

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

How we are shaped: the biomechanics of gastrulation

21 January 2018

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21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Force generation, transmission, and integration during cell and tissue morphogenesis

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

folded gastrulation, cell shape change and the control of myosin localization.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Tissue elongation requires oscillating contractions of a basal actomyosin network

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Compartmentalisation of Rho regulators directs cell invagination during tissue morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Drosophila Rho-associated kinase (Drok) links Frizzled-mediated planar cell polarity signaling to the actin cytoskeleton.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Coordination of Rho GTPase activities during cell protrusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Redox-dependent downregulation of Rho by Rac.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Rac activation and inactivation control plasticity of tumor cell movement

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Myosin-dependent junction remodelling controls planar cell intercalation and axis elongation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Patterned gene expression directs bipolar planar polarity in Drosophila

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Nature and anisotropy of cortical forces orienting Drosophila tissue morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

A tension-induced mechanotransduction pathway promotes epithelial morphogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Paxillin phosphorylation at Ser273 localizes a GIT1-PIX-PAK complex and regulates adhesion and protrusion dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Apical constriction and invagination downstream of the canonical Wnt signaling pathway require Rho1 and Myosin II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Drosophila Myosin II, Zipper, is essential for ommatidial rotation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Polarity reveals intrinsic cell chirality

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Regulation of protrusion, adhesion dynamics, and polarity by myosins IIA and IIB in migrating cells

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Cortical forces in cell shape changes and tissue morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Cortical flows powered by asymmetrical contraction transport PAR proteins to establish and maintain anterior-posterior polarity in the early C. elegans embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Anisotropies in cortical tension reveal the physical basis of polarizing cortical flows

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Forces driving epithelial spreading in zebrafish gastrulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Mechanical integration of actin and adhesion dynamics in cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

A tense situation: forcing tumour progression

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Tumour-cell invasion and migration: diversity and escape mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Requirement of Nck adaptors for actin dynamics and cell migration stimulated by platelet-derived growth factor B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Drug resistance and the solid tumor microenvironment

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Matrix metalloproteinases and tumor metastasis

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Lysyl oxidase: an oxidative enzyme and effector of cell function

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Basic mechanism of three-dimensional collagen fibre transport by fibroblasts.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Tensional homeostasis and the malignant phenotype

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Actomyosin-mediated cellular tension drives increased tissue stiffness and β-catenin activation to induce epidermal hyperplasia and tumor growth

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Integrin-dependent actomyosin contraction regulates epithelial cell scattering.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Epithelial morphogenesis in embryos: asymmetries, motors and brakes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Plasticity of cell migration: a multiscale tuning model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Dynamic interplay between the collagen scaffold and tumor evolution

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

The epithelial-mesenchymal transition under control: global programs to regulate epithelial plasticity.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

RETRACTED: Lysyl oxidase is essential for hypoxia-induced metastasis

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Lysyl oxidase-like 2 (LOXL2), a new regulator of cell polarity required for metastatic dissemination of basal-like breast carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Simultaneous imaging of GFP, CFP and collagen in tumors in vivo using multiphoton microscopy

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Non-equilibration of hydrostatic pressure in blebbing cells.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Rapid leukocyte migration by integrin-independent flowing and squeezing

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Cell mechanics control rapid transitions between blebs and lamellipodia during migration

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

The secret life of α-catenin: moonlighting in morphogenesis

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

A Rho GTPase signaling pathway is used reiteratively in epithelial folding and potentially selects the outcome of Rho activation.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

The nanomechanical signature of breast cancer

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00018-013-1439-5

Identification, phosphorylation, and dephosphorylation of a second site for myosin light chain kinase on the 20,000-dalton light chain of smooth muscle myosin

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23934154

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Attachment, spreading and locomotion of avian neural crest cells are mediated by multiple adhesion sites on fibronectin molecules

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23934154

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S00018-013-1439-5

1 reference

29 August 2017

1 reference