(Q38130112)

29 August 2017

Cardiovascular autophagy: concepts, controversies, and perspectives (English)

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29 August 2017

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Sergio Lavandero

1

1 reference

29 August 2017

Rodrigo Troncoso

2

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29 August 2017

Beverly A Rothermel

3

1 reference

29 August 2017

Wim Martinet

4

1 reference

29 August 2017

Junichi Sadoshima

5

1 reference

29 August 2017

Joseph A Hill

6

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29 August 2017

14 August 2013

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29 August 2017

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29 August 2017

9

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29 August 2017

10

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29 August 2017

1455-1466

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Heart Disease and Stroke Statistics--2013 Update: A Report From the American Heart Association

29 August 2017

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Executive Summary: Heart Disease and Stroke Statistics—2010 Update

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Energy metabolic phenotype of the cardiomyocyte during development, differentiation, and postnatal maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Phenotypic plasticity of adult myocardium: molecular mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Remodeling and reparation of the cardiovascular system

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Subcellular remodeling as a viable target for the treatment of congestive heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Energy metabolism in heart failure and remodelling

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Vascular remodeling in hypertension: roles of apoptosis, inflammation, and fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Cardiac hypertrophy: the good, the bad, and the ugly

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Pathological ventricular remodeling: mechanisms: part 1 of 2

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Cardiac autophagy is a maladaptive response to hemodynamic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Intracellular protein aggregation is a proximal trigger of cardiomyocyte autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Autophagy is an adaptive response in desmin-related cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Accumulation of autophagic vacuoles and cardiomyopathy in LAMP-2-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Myocytes die by multiple mechanisms in failing human hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

21 January 2018

The lysosome turns fifty

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Autophagy: from phenomenology to molecular understanding in less than a decade

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Autophagy fights disease through cellular self-digestion

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Autophagic cell death: the story of a misnomer

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Self-eating and self-killing: crosstalk between autophagy and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

21 January 2018

How shall I eat thee?

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Autophagy: many paths to the same end.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Cardiomyocyte ryanodine receptor degradation by chaperone-mediated autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Dynamics and diversity in autophagy mechanisms: lessons from yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Regulation mechanisms and signaling pathways of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

The role of the Atg1/ULK1 complex in autophagy regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Tor-mediated induction of autophagy via an Apg1 protein kinase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

DAP1, a novel substrate of mTOR, negatively regulates autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

p62 at the crossroads of autophagy, apoptosis, and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

The elimination of accumulated and aggregated proteins: a role for aggrephagy in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

The regulation of autophagy - unanswered questions

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

mTOR signaling in growth control and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Mammalian target of rapamycin complex 1: signalling inputs, substrates and feedback mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

mTOR complex 2 signaling and functions

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Distinct classes of phosphatidylinositol 3'-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

AMP-activated Protein Kinase and the Regulation of Autophagic Proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

TSC2 mediates cellular energy response to control cell growth and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

LKB1 and AMP-activated protein kinase control of mTOR signalling and growth

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

AMPK in Health and Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

The AMPK signalling pathway coordinates cell growth, autophagy and metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Energy-preserving effects of IGF-1 antagonize starvation-induced cardiac autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

The inositol trisphosphate receptor in the control of autophagy.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Essential regulation of cell bioenergetics by constitutive InsP3 receptor Ca2+ transfer to mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

A dual role of p53 in the control of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Autophagy regulation by p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

The regulation of AMPK beta1, TSC2, and PTEN expression by p53: stress, cell and tissue specificity, and the role of these gene products in modulating the IGF-1-AKT-mTOR pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

DRAM, a p53-induced modulator of autophagy, is critical for apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Regulation of autophagy by cytoplasmic p53

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

TIGAR, a p53-inducible regulator of glycolysis and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

p53-TIGAR axis attenuates mitophagy to exacerbate cardiac damage after ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Protein kinase A is a target for aging and the aging heart

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Mitochondria regulate autophagy by conserved signalling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Novel targets for Huntington's disease in an mTOR-independent autophagy pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Suppression of class I and II histone deacetylases blunts pressure-overload cardiac hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Histone deacetylase (HDAC) inhibitors attenuate cardiac hypertrophy by suppressing autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Titrating autophagy in cardiac plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Differential roles of GSK-3β during myocardial ischemia and ischemia/reperfusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

The NAD World: a new systemic regulatory network for metabolism and aging--Sirt1, systemic NAD biosynthesis, and their importance

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Nicotinamide phosphoribosyltransferase regulates cell survival through autophagy in cardiomyocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Deacetylation of FoxO by Sirt1 Plays an Essential Role in Mediating Starvation-Induced Autophagy in Cardiac Myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Exogenous NAD blocks cardiac hypertrophic response via activation of the SIRT3-LKB1-AMP-activated kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

MicroRNAs: target recognition and regulatory functions

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Therapeutic use of microRNAs in myocardial diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

The miRNA-212/132 family regulates both cardiac hypertrophy and cardiomyocyte autophagy.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Clinical outcome and phenotypic expression in LAMP2 cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Functional significance and morphological characterization of starvation-induced autophagy in the adult heart

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Autophagy in hypertensive heart disease

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Autophagy plays an essential role in mediating regression of hypertrophy during unloading of the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Mechanical unloading activates FoxO3 to trigger Bnip3-dependent cardiomyocyte atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Urocortin inhibits Beclin1-mediated autophagic cell death in cardiac myocytes exposed to ischaemia/reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Enhancing macroautophagy protects against ischemia/reperfusion injury in cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Autophagy in chronically ischemic myocardium.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Autophagy induced by ischemic preconditioning is essential for cardioprotection.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Impaired autophagosome clearance contributes to cardiomyocyte death in ischemia/reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Autophagy is impaired in cardiac ischemia-reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Doxorubicin-induced cardiomyopathy: from molecular mechanisms to therapeutic strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Adriamycin-induced autophagic cardiomyocyte death plays a pathogenic role in a rat model of heart failure.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Transcription factor GATA4 inhibits doxorubicin-induced autophagy and cardiomyocyte death

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Caloric restriction mimetic 2-deoxyglucose antagonizes doxorubicin-induced cardiomyocyte death by multiple mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Resveratrol attenuates doxorubicin-induced cardiomyocyte death via inhibition of p70 S6 kinase 1-mediated autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Prior starvation mitigates acute doxorubicin cardiotoxicity through restoration of autophagy in affected cardiomyocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Autophagy signaling through reactive oxygen species.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Unsaturated lipid peroxidation-derived aldehydes activate autophagy in vascular smooth-muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

7-ketocholesterol induces protein ubiquitination, myelin figure formation, and light chain 3 processing in vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

HDLs inhibit endoplasmic reticulum stress and autophagic response induced by oxidized LDLs

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

The autophagy-lysosome pathway: a novel mechanism involved in the processing of oxidized LDL in human vascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Endoplasmic reticulum stress triggers autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Increased expression of the DNA-binding cytokine HMGB1 in human atherosclerotic lesions: role of activated macrophages and cytokines.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Autophagy plays a protective role in free cholesterol overload-induced death of smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

No upregulation of lectin-like oxidized low-density lipoprotein receptor-1 in serum-deprived EA.hy926 endothelial cells under oxLDL exposure, but increase in autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Macrophage autophagy plays a protective role in advanced atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Autophagy links inflammasomes to atherosclerotic progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Autophagy in atherosclerosis: a potential drug target for plaque stabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Drug-induced macrophage autophagy in atherosclerosis: for better or worse?

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Everolimus inhibits monocyte/macrophage migration in vitro and their accumulation in carotid lesions of cholesterol-fed rabbits.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Sirolimus inhibits endogenous cholesterol synthesis induced by inflammatory stress in human vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Everolimus-induced mTOR inhibition selectively depletes macrophages in atherosclerotic plaques by autophagy.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Selective clearance of macrophages in atherosclerotic plaques by autophagy.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Toll-like receptors control autophagy.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

MyD88 and Trif target Beclin 1 to trigger autophagy in macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Pharmacological modulation of autophagy during cardiac stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Regulation of mammalian autophagy in physiology and pathophysiology.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

Increased myocardial cathepsin D activity during regression of thyrotoxic cardiac hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.25969

21 January 2018

Identifiers

DOI

10.4161/AUTO.25969

1 reference

29 August 2017

1 reference