(Q38144839)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24072169%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

title

Mutation rate and the emergence of drug resistance in Mycobacterium tuberculosis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24072169%20AND%20SRC:MED&resulttype=core&format=json

Mycobacterium tuberculosis

23 February 2020

main subject

0 references

author

Nicolaas C Gey van Pittius

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24072169%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Robin M. Warren

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24072169%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Digby F Warner

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24072169%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

author name string

M McGrath

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24072169%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

P D van Helden

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24072169%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

language of work or name

English

0 references

publication date

26 September 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24072169%20AND%20SRC:MED&resulttype=core&format=json

Journal of Antimicrobial Chemotherapy

23 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24072169%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

volume

69

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24072169%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24072169%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

page(s)

292-302

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24072169%20AND%20SRC:MED&resulttype=core&format=json

Rates and mechanisms of resistance development in Mycobacterium tuberculosis to a novel diarylquinoline ATP synthase inhibitor

23 February 2020

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Error-prone replication for better or worse

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Resistant mutants of Mycobacterium tuberculosis selected in vitro do not reflect the in vivo mechanism of isoniazid resistance

21 January 2018

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Drug-susceptible Mycobacterium tuberculosis Beijing genotype does not develop mutation-conferred resistance to rifampin at an elevated rate

21 January 2018

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Role of the DinB homologs Rv1537 and Rv3056 in Mycobacterium tuberculosis

21 January 2018

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Use of whole genome sequencing to estimate the mutation rate of Mycobacterium tuberculosis during latent infection

21 January 2018

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Pre-existing isoniazid resistance, but not the genotype of Mycobacterium tuberculosis drives rifampicin resistance codon preference in vitro

21 January 2018

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Effect of subinhibitory concentrations of ciprofloxacin on Mycobacterium fortuitum mutation rates

21 January 2018

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Systematic analysis of pyrazinamide-resistant spontaneous mutants and clinical isolates of Mycobacterium tuberculosis

21 January 2018

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How antibiotics kill bacteria: from targets to networks

21 January 2018

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Host-directed drug targeting of factors hijacked by pathogens

21 January 2018

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DNA repair in Mycobacterium tuberculosis. What have we learnt from the genome sequence?

21 January 2018

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Spontaneous mutators in bacteria: insights into pathways of mutagenesis and repair

21 January 2018

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Stabilization of the genome of the mismatch repair deficient Mycobacterium tuberculosis by context-dependent codon choice

21 January 2018

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A study on mutational dynamics of simple sequence repeats in relation to mismatch repair system in prokaryotic genomes.

21 January 2018

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In vitro analysis of rates and spectra of mutations in a polymorphic region of the Rv0746 PE_PGRS gene of Mycobacterium tuberculosis

21 January 2018

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Characterization of the mycobacterial NER system reveals novel functions of the uvrD1 helicase

21 January 2018

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Lack of mismatch correction facilitates genome evolution in mycobacteria.

21 January 2018

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Modeling the emergence of the 'hot zones': tuberculosis and the amplification dynamics of drug resistance

21 January 2018

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Modeling epidemics of multidrug-resistant M. tuberculosis of heterogeneous fitness

21 January 2018

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Multidrug-resistant tuberculosis not due to noncompliance but to between-patient pharmacokinetic variability

21 January 2018

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On the rapidity of antibiotic resistance evolution facilitated by a concentration gradient.

21 January 2018

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Spontaneous emergence of multiple drug resistance in tuberculosis before and during therapy

21 January 2018

1 reference

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Deep resequencing of serial sputum isolates of Mycobacterium tuberculosis during therapeutic failure due to poor compliance reveals stepwise mutation of key resistance genes on an otherwise stable genetic background.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Dynamic population changes in Mycobacterium tuberculosis during acquisition and fixation of drug resistance in patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Drug resistance evolution of a Mycobacterium tuberculosis strain from a noncompliant patient.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Dynamics of antibiotic resistant Mycobacterium tuberculosis during long-term infection and antibiotic treatment

21 January 2018

1 reference

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Mycobacterium tuberculosis growth at the cavity surface: a microenvironment with failed immunity

21 January 2018

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Doomsday postponed? Preventing and reversing epidemics of drug-resistant tuberculosis

21 January 2018

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Mutation frequencies and antibiotic resistance

21 January 2018

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Linking the transcriptional profiles and the physiological states of Mycobacterium tuberculosis during an extended intracellular infection

21 January 2018

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A replication clock for Mycobacterium tuberculosis

21 January 2018

1 reference

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Defining the requirements for immunological control of mycobacterial infections

21 January 2018

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Replication dynamics of Mycobacterium tuberculosis in chronically infected mice

21 January 2018

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The spectrum of latent tuberculosis: rethinking the biology and intervention strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Oxygen status of lung granulomas in Mycobacterium tuberculosis-infected mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Tuberculous granulomas are hypoxic in guinea pigs, rabbits, and nonhuman primates

21 January 2018

1 reference

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The Mycobacterium tuberculosis stress response factor SigH is required for bacterial burden as well as immunopathology in primate lungs.

21 January 2018

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Evolution and diversity of clonal bacteria: the paradigm of Mycobacterium tuberculosis

21 January 2018

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Evolution of mutation rates in bacteria

21 January 2018

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Mutational spectrum drives the rise of mutator bacteria

21 January 2018

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Mutations in putative mutator genes of Mycobacterium tuberculosis strains of the W-Beijing family

21 January 2018

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Mycobacterium tuberculosis Beijing strains favor transmission but not drug resistance in China

21 January 2018

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The non-clonality of drug resistance in Beijing-genotype isolates of Mycobacterium tuberculosis from the Western Cape of South Africa

21 January 2018

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Making sense of a missense mutation: characterization of MutT2, a Nudix hydrolase from Mycobacterium tuberculosis, and the G58R mutant encoded in W-Beijing strains of M. tuberculosis.

21 January 2018

1 reference

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Identification of Nudix hydrolase family members with an antimutator role in Mycobacterium tuberculosis and Mycobacterium smegmatis.

21 January 2018

1 reference

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Biochemical properties of MutT2 proteins from Mycobacterium tuberculosis and M. smegmatis and their contrasting antimutator roles in Escherichia coli

21 January 2018

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Drug susceptibility of Mycobacterium tuberculosis Beijing genotype and association with MDR TB.

21 January 2018

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Consequences of noncompliance for therapy efficacy and emergence of resistance in murine tuberculosis caused by the Beijing genotype of Mycobacterium tuberculosis

21 January 2018

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DNA repair in Mycobacterium tuberculosis revisited

21 January 2018

1 reference

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Effect of mutation and genetic background on drug resistance in Mycobacterium tuberculosis

21 January 2018

1 reference

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Mycobacterium tuberculosis mutation rate estimates from different lineages predict substantial differences in the emergence of drug-resistant tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Acquisition of rifabutin resistance by a rifampicin resistant mutant of Mycobacterium tuberculosis involves an unusual spectrum of mutations and elevated frequency

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Specific mutations in the Mycobacterium tuberculosis rpoB gene are associated with increased dnaE2 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Essential roles for imuA'- and imuB-encoded accessory factors in DnaE2-dependent mutagenesis in Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Stress-induced mutagenesis in bacteria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Novel role of mfd: effects on stationary-phase mutagenesis in Bacillus subtilis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Key role of Mfd in the development of fluoroquinolone resistance in Campylobacter jejuni

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Abasic sites and strand breaks in DNA cause transcriptional mutagenesis in Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

RNA polymerase encounters with DNA damage: transcription-coupled repair or transcriptional mutagenesis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Transcriptional mutagenesis induced by 8-oxoguanine in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

DnaE2 polymerase contributes to in vivo survival and the emergence of drug resistance in Mycobacterium tuberculosis

21 January 2018

1 reference

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Too many mutants with multiple mutations

21 January 2018

1 reference

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Distinct properties of hexameric but functionally conserved Mycobacterium tuberculosis transcription-repair coupling factor

21 January 2018

1 reference

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Cellular mechanisms that control mistranslation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

An editing-defective aminoacyl-tRNA synthetase is mutagenic in aging bacteria via the SOS response

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Mutator tRNAs are encoded by the Escherichia coli mutator genes mutA and mutC: a novel pathway for mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Global analysis of the regulon of the transcriptional repressor LexA, a key component of SOS response in Mycobacterium tuberculosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

ClpR protein-like regulator specifically recognizes RecA protein-independent promoter motif and broadly regulates expression of DNA damage-inducible genes in mycobacteria

21 January 2018

1 reference

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Mechanism of nonhomologous end-joining in mycobacteria: a low-fidelity repair system driven by Ku, ligase D and ligase C

21 January 2018

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Mycobacterial nonhomologous end joining mediates mutagenic repair of chromosomal double-strand DNA breaks

21 January 2018

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DNA repair systems and the pathogenesis of Mycobacterium tuberculosis: varying activities at different stages of infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

NHEJ protects mycobacteria in stationary phase against the harmful effects of desiccation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Vibrio cholerae triggers SOS and mutagenesis in response to a wide range of antibiotics: a route towards multiresistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

The transcription elongation factor NusA is required for stress-induced mutagenesis in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

β-Lactam antibiotics promote bacterial mutagenesis via an RpoS-mediated reduction in replication fidelity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Sublethal antibiotic treatment leads to multidrug resistance via radical-induced mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Effect of recA inactivation on mutagenesis of Escherichia coli exposed to sublethal concentrations of antimicrobials.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Pharmacokinetic evaluation of the penetration of antituberculosis agents in rabbit pulmonary lesions

21 January 2018

1 reference

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Pharmacogenomic Research in South Africa: Lessons Learned and Future Opportunities in the Rainbow Nation.

21 January 2018

1 reference

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Empirical treatment of community-acquired pneumonia and the development of fluoroquinolone-resistant tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Mycobacterium tuberculosis DNA repair in response to subinhibitory concentrations of ciprofloxacin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Induction of mycobacterial resistance to quinolone class antimicrobials

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Oxidation of the guanine nucleotide pool underlies cell death by bactericidal antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Eradication of bacterial persisters with antibiotic-generated hydroxyl radicals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Cell death from antibiotics without the involvement of reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Inhibition of mutation and combating the evolution of antibiotic resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

The transcriptional responses of Mycobacterium tuberculosis to inhibitors of metabolism: novel insights into drug mechanisms of action

21 January 2018

1 reference

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Mechanisms of action of isoniazid

21 January 2018

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Identifying co-targets to fight drug resistance based on a random walk model

21 January 2018

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The use of microarray analysis to determine the gene expression profiles of Mycobacterium tuberculosis in response to anti-bacterial compounds.

21 January 2018

1 reference

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The changing epidemiology of acquired drug-resistant tuberculosis in San Francisco, USA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Modeling the dynamic relationship between HIV and the risk of drug-resistant tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

WR1065 mitigates AZT-ddI-induced mutagenesis and inhibits viral replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Genetic risks of antiviral nucleoside analogues--a survey

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Induction of the SOS response in Escherichia coli by azidothymidine and dideoxynucleosides

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Nucleoside reverse transcriptase inhibitors and HIV mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Unique transcriptome signature of Mycobacterium tuberculosis in pulmonary tuberculosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Transcriptional responses of Mycobacterium tuberculosis to lung surfactant

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

A distinct role of formamidopyrimidine DNA glycosylase (MutM) in down-regulation of accumulation of G, C mutations and protection against oxidative stress in mycobacteria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Mycobacterial survival strategies in the phagosome: defence against host stresses

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

A distinct physiological role of MutY in mutation prevention in mycobacteria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Detrimental effects of hypoxia-specific expression of uracil DNA glycosylase (Ung) in Mycobacterium smegmatis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Synergistic effects of UdgB and Ung in mutation prevention and protection against commonly encountered DNA damaging agents in Mycobacterium smegmatis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Base excision and nucleotide excision repair pathways in mycobacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Analysis of rpoB and pncA mutations in the published literature: an insight into the role of oxidative stress in Mycobacterium tuberculosis evolution?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Use of site-directed mutagenesis to probe the structure, function and isoniazid activation of the catalase/peroxidase, KatG, from Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Exploring the structure and function of the mycobacterial KatG protein using trans-dominant mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Enhanced heterogeneity of rpoB in Mycobacterium tuberculosis found at low pH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Rates of drug resistance and risk factor analysis in civilian and prison patients with tuberculosis in Samara Region, Russia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Prevalence of and risk factors for resistance to second-line drugs in people with multidrug-resistant tuberculosis in eight countries: a prospective cohort study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Predicting the mutagenicity of tobacco-related N-nitrosamines in humans using 11 strains of Salmonella typhimurium YG7108, each coexpressing a form of human cytochrome P450 along with NADPH-cytochrome P450 reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Bacterial mutagenicity of some tobacco aromatic nitrogen bases and their mixtures

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Redox homeostasis in mycobacteria: the key to tuberculosis control?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Detection and treatment of subclinical tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

Mutations in mutT genes of Mycobacterium tuberculosis isolates of Beijing genotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT364

21 January 2018

Identifiers

DOI

10.1093/JAC/DKT364

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24072169%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

1 reference