(Q47215316)

11 January 2018

title

The transcriptional responses of Mycobacterium tuberculosis to inhibitors of metabolism: novel insights into drug mechanisms of action (English)

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11 January 2018

Mycobacterium tuberculosis

main subject

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author

Brent R Copp

3

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Clifton E Barry

object named as

Clifton E Barry

6

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author name string

Helena I M Boshoff

1

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11 January 2018

Timothy G Myers

2

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11 January 2018

Michael R McNeil

4

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Michael A Wilson

5

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language of work or name

English

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publication date

9 July 2004

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11 January 2018

Journal of Biological Chemistry

published in

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volume

279

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issue

38

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page(s)

40174-40184

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11 January 2018

Genome-wide expression profiling of the response to polyene, pyrimidine, azole, and echinocandin antifungal agents in Saccharomyces cerevisiae

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406796200

Signature gene expression profiles discriminate between isoniazid-, thiolactomycin-, and triclosan-treated Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406796200

Exploring drug-induced alterations in gene expression in Mycobacterium tuberculosis by microarray hybridization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406796200

Inhibition of respiration by nitric oxide induces a Mycobacterium tuberculosis dormancy program

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406796200

The role of RelMtb-mediated adaptation to stationary phase in long-term persistence of Mycobacterium tuberculosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406796200

Use of gene networks from full genome microarray libraries to identify functionally relevant drug-affected genes and gene regulation cascades

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406796200

Transcriptional Adaptation of Mycobacterium tuberculosis within Macrophages: Insights into the Phagosomal Environment

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406796200

DnaE2 polymerase contributes to in vivo survival and the emergence of drug resistance in Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406796200

Expression of Mycobacterium smegmatis pyrazinamidase in Mycobacterium tuberculosis confers hypersensitivity to pyrazinamide and related amides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406796200

Combinatorial lead optimization of [1,2]-diamines based on ethambutol as potential antituberculosis preclinical candidates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406796200

The salicylate-derived mycobactin siderophores of Mycobacterium tuberculosis are essential for growth in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406796200

Recognition of multiple effects of ethambutol on metabolism of mycobacterial cell envelope

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406796200

Metabolic engineering through cofactor manipulation and its effects on metabolic flux redistribution in Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406796200

Isoniazid affects multiple components of the type II fatty acid synthase system of Mycobacterium tuberculosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406796200

Analysis of large-scale gene expression data

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406796200

Definition of the mycobacterial SOS box and use to identify LexA-regulated genes in Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406796200

The stringent response of Mycobacterium tuberculosis is required for long-term survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406796200

Role of inorganic polyphosphate in promoting ribosomal protein degradation by the Lon protease in E. coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406796200

A polyphosphate kinase (PPK2) widely conserved in bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406796200

A homodimeric sporamin-type trypsin inhibitor with antiproliferative, HIV reverse transcriptase-inhibitory and antifungal activities from wampee (Clausena lansium) seeds

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406796200

Mechanism of fluoroquinolone action

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406796200

Ribonucleotide reductase: regulation, regulation, regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406796200

Ribonucleotide Reduction in Mycobacterium tuberculosis : Function and Expression of Genes Encoding Class Ib and Class II Ribonucleotide Reductases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406796200

Characterization of the Mycobacterium tuberculosis iniBAC promoter, a promoter that responds to cell wall biosynthesis inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406796200

Evolution and spread of antibiotic resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406796200

The embAB genes of Mycobacterium avium encode an arabinosyl transferase involved in cell wall arabinan biosynthesis that is the target for the antimycobacterial drug ethambutol

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406796200

Truncated structural variants of lipoarabinomannan in ethambutol drug-resistant strains of Mycobacterium smegmatis. Inhibition of arabinan biosynthesis by ethambutol

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406796200

A polyketide synthase catalyzes the last condensation step of mycolic acid biosynthesis in mycobacteria and related organisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406796200

Lipid biosynthesis as a target for antibacterial agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406796200

Azole antifungals are potent inhibitors of cytochrome P450 mono-oxygenases and bacterial growth in mycobacteria and streptomycetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406796200

Inhibition of mitochondrial complex I by haloperidol: the role of thiol oxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406796200

Activity of phenothiazines against antibiotic-resistant Mycobacterium tuberculosis: a review supporting further studies that may elucidate the potential use of thioridazine as anti-tuberculosis therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406796200

Cytochromes P450: novel drug targets in the war against multidrug-resistant Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406796200

Characterization of the cydAB-encoded cytochrome bd oxidase from Mycobacterium smegmatis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406796200

The unorthodox histidine kinases BvgS and EvgS are responsive to the oxidation status of a quinone electron carrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406796200

Oxygen control of nif gene expression in Klebsiella pneumoniae depends on NifL reduction at the cytoplasmic membrane by electrons derived from the reduced quinone pool

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406796200

A novel sensor of NADH/NAD+ redox poise in Streptomyces coelicolor A3(2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406796200

Mechanism of ascididemin-induced cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406796200

Genes required for mycobacterial growth defined by high density mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406796200

Regulation of the Mycobacterium tuberculosis hypoxic response gene encoding α-crystallin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406796200

Redundancy of aerobic respiratory chains in bacteria? Routes, reasons and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406796200

Superoxide dismutase as a target for the selective killing of cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M406796200

21 January 2018

Identifiers

DOI

10.1074/JBC.M406796200

1 reference

11 January 2018

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11 January 2018