(Q38145001)

29 August 2017

title

Epigenetics in rheumatoid arthritis: a primer for rheumatologists (English)

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29 August 2017

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Nunzio Bottini

1

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29 August 2017

Gary S Firestein

series ordinal

2

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29 August 2017

publication date

1 November 2013

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Current Rheumatology Reports

29 August 2017

published in

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29 August 2017

volume

15

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29 August 2017

issue

11

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29 August 2017

page(s)

372

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Rheumatoid arthritis genetics: 2009 update

29 August 2017

cites work

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CD40L demethylation in CD4(+) T cells from women with rheumatoid arthritis.

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Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus

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Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis

21 January 2018

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Retrotransposable L1 elements expressed in rheumatoid arthritis synovial tissue: association with genomic DNA hypomethylation and influence on gene expression

21 January 2018

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The L1 retroelement-related p40 protein induces p38delta MAP kinase

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DNA hypomethylation in rheumatoid arthritis synovial fibroblasts.

21 January 2018

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Regulation of DNA methylation in rheumatoid arthritis synoviocytes

21 January 2018

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DNA methylation regulates the expression of CXCL12 in rheumatoid arthritis synovial fibroblasts

21 January 2018

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Hypermethylated promoter region of DR3, the death receptor 3 gene, in rheumatoid arthritis synovial cells.

21 January 2018

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Expression and function of wingless and frizzled homologs in rheumatoid arthritis.

21 January 2018

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MeCP2 modulates the canonical Wnt pathway activation by targeting SFRP4 in rheumatoid arthritis fibroblast-like synoviocytes in rats

21 January 2018

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DNA methylome signature in rheumatoid arthritis

21 January 2018

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An imprinted rheumatoid arthritis methylome signature reflects pathogenic phenotype

21 January 2018

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Identification of novel markers in rheumatoid arthritis through integrated analysis of DNA methylation and microRNA expression

21 January 2018

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Histone acetyltransferase mediated regulation of FOXP3 acetylation and Treg function

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21 January 2018

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21 January 2018

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Histone deacetylase inhibitors suppress rheumatoid arthritis fibroblast-like synoviocyte and macrophage IL-6 production by accelerating mRNA decay

21 January 2018

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Histone deacetylases are dysregulated in rheumatoid arthritis and a novel histone deacetylase 3-selective inhibitor reduces interleukin-6 production by peripheral blood mononuclear cells from rheumatoid arthritis patients

21 January 2018

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Deacetylase inhibition increases regulatory T cell function and decreases incidence and severity of collagen-induced arthritis

21 January 2018

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Histone deacetylase/acetylase activity in total synovial tissue derived from rheumatoid arthritis and osteoarthritis patients

21 January 2018

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Epigenetics and rheumatoid arthritis: the role of SENP1 in the regulation of MMP-1 expression

21 January 2018

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Expression and function of histone deacetylases in rheumatoid arthritis synovial fibroblasts.

21 January 2018

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21 January 2018

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Anti-arthritic effects of combined treatment with histone deacetylase inhibitor and low-intensity ultrasound in the presence of microbubbles in human rheumatoid synovial cells

21 January 2018

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Histone deacetylase inhibitors MS-275 and SAHA induced growth arrest and suppressed lipopolysaccharide-stimulated NF-kappaB p65 nuclear accumulation in human rheumatoid arthritis synovial fibroblastic E11 cells

21 January 2018

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A therapeutic strategy uses histone deacetylase inhibitors to modulate the expression of genes involved in the pathogenesis of rheumatoid arthritis

21 January 2018

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Anti-rheumatic activities of histone deacetylase (HDAC) inhibitors in vivo in collagen-induced arthritis in rodents.

21 January 2018

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Inhibition of HDAC activity by ITF2357 ameliorates joint inflammation and prevents cartilage and bone destruction in experimental arthritis

21 January 2018

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MicroRNA-124a is a key regulator of proliferation and monocyte chemoattractant protein 1 secretion in fibroblast-like synoviocytes from patients with rheumatoid arthritis

21 January 2018

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Upregulated miR-146a expression in peripheral blood mononuclear cells from rheumatoid arthritis patients

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11926-013-0372-9

microRNAs in rheumatoid arthritis: midget RNAs with a giant impact

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11926-013-0372-9

What do microRNAs mean for rheumatoid arthritis?

21 January 2018

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Novel regulatory mechanisms in inflammatory arthritis: a role for microRNA.

21 January 2018

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MicroRNA-155 promotes autoimmune inflammation by enhancing inflammatory T cell development

21 January 2018

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Pre-B cell proliferation and lymphoblastic leukemia/high-grade lymphoma in E(mu)-miR155 transgenic mice

21 January 2018

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MicroRNA-146a expresses in interleukin-17 producing T cells in rheumatoid arthritis patients

21 January 2018

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Altered expression of MicroRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis

21 January 2018

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Identification of microRNA-221/222 and microRNA-323-3p association with rheumatoid arthritis via predictions using the human tumour necrosis factor transgenic mouse model

21 January 2018

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MicroRNA-155 as a proinflammatory regulator in clinical and experimental arthritis

21 January 2018

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NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11926-013-0372-9

Expression of microRNA-146 in rheumatoid arthritis synovial tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11926-013-0372-9

Altered microRNA expression profile with miR-146a upregulation in CD4+ T cells from patients with rheumatoid arthritis

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11926-013-0372-9

Association of polymorphisms in pre-miRNA with inflammatory biomarkers in rheumatoid arthritis in the Chinese Han population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11926-013-0372-9

TLR2 expression is regulated by microRNA miR-19 in rheumatoid fibroblast-like synoviocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11926-013-0372-9

A miR-19 regulon that controls NF-κB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11926-013-0372-9

miR-223 is overexpressed in T-lymphocytes of patients affected by rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11926-013-0372-9

Plasma and synovial fluid microRNAs as potential biomarkers of rheumatoid arthritis and osteoarthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11926-013-0372-9

Altered expression of microRNA-203 in rheumatoid arthritis synovial fibroblasts and its role in fibroblast activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11926-013-0372-9

Down-regulation of microRNA-34a* in rheumatoid arthritis synovial fibroblasts promotes apoptosis resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11926-013-0372-9

Bruton's tyrosine kinase is involved in miR-346-related regulation of IL-18 release by lipopolysaccharide-activated rheumatoid fibroblast-like synoviocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11926-013-0372-9

miR-346 controls release of TNF-α protein and stability of its mRNA in rheumatoid arthritis via tristetraprolin stabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11926-013-0372-9

Induction of apoptosis in the synovium of mice with autoantibody-mediated arthritis by the intraarticular injection of double-stranded MicroRNA-15a.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11926-013-0372-9

Tumor Necrosis Factor α-Induced MicroRNA-18a Activates Rheumatoid Arthritis Synovial Fibroblasts Through a Feedback Loop in NF-κB Signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11926-013-0372-9

Essential role of microRNA-155 in the pathogenesis of autoimmune arthritis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11926-013-0372-9

The inhibitory effect of microRNA-146a expression on bone destruction in collagen-induced arthritis

21 January 2018

1 reference

12 December 2020

The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-α

1 reference

12 December 2020

Evidence for impaired T cell DNA methylation in systemic lupus erythematosus and rheumatoid arthritis

1 reference

12 December 2020

Increased recycling of polyamines is associated with global DNA hypomethylation in rheumatoid arthritis synovial fibroblasts

1 reference

12 December 2020

A polymorphism in the 3’-UTR of interleukin-1 receptor-associated kinase (IRAK1), a target gene of miR-146a, is associated with rheumatoid arthritis susceptibility

1 reference

12 December 2020

MiR-146a polymorphism is associated with asthma but not with systemic lupus erythematosus and juvenile rheumatoid arthritis in Mexican patients

1 reference

12 December 2020

Safety and efficacy of an oral histone deacetylase inhibitor in systemic-onset juvenile idiopathic arthritis

1 reference

12 December 2020

Expression and function of EZH2 in synovial fibroblasts: epigenetic repression of the Wnt inhibitor SFRP1 in rheumatoid arthritis

1 reference

12 December 2020

5-Methylcytosine content of DNA in blood, synovial mononuclear cells and synovial tissue from patients affected by autoimmune rheumatic diseases

1 reference

12 December 2020

SIRT1 overexpression in the rheumatoid arthritis synovium contributes to proinflammatory cytokine production and apoptosis resistance

1 reference

12 December 2020

Brief report: amelioration of collagen-induced arthritis in mice by lentivirus-mediated silencing of microRNA-223

1 reference

12 December 2020

The ascent of acetylation in the epigenetics of rheumatoid arthritis

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12 December 2020

cAMP signalling inhibits p53 acetylation and apoptosis via HDAC and SIRT deacetylases

1 reference

12 December 2020

Global DNA methylation, DNMT1, and MBD2 in patients with rheumatoid arthritis

1 reference

12 December 2020

10.1007/S11926-013-0372-9

Identifiers

DOI

1 reference

Dimensions Publication ID

29 August 2017

1047989019

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